Astilbin reduces ROS accumulation and VEGF expression through Nrf2 in psoriasis-like skin disease
Psoriasis is a common and intractable skin disease affecting the physical and mental health of patients. The accumulation of ROS is involved in the pathogenesis of psoriasis and antioxidants are believed to be... (Source: Biological Research)
Source: Biological Research - September 6, 2019 Category: Biomedical Science Authors: Wuyuntana Wang, Yuhai, Huan Wang, Chasuna and Bagenna Tags: Research article Source Type: research
Rhein alleviates renal interstitial fibrosis by inhibiting tubular cell apoptosis in rats
Ureteral obstruction causes injury of the renal tissues and can irreversibly progress to renal fibrosis, with atrophy and apoptosis of tubular cells. The goal of the current study was to examine the effects of... (Source: Biological Research)
Source: Biological Research - September 6, 2019 Category: Biomedical Science Authors: Yakun Chen, Lin Mu, Lingling Xing, Shaomei Li and Shuxia Fu Tags: Research article Source Type: research
Light-induced injury in mouse embryos revealed by single-cell RNA sequencing
Light exposure is a common stress factor in in vitro manipulation of embryos in the reproductive center. Many studies have shown the deleterious effects of high-intensity light exposure in different animal emb... (Source: Biological Research)
Source: Biological Research - August 29, 2019 Category: Biomedical Science Authors: Bo Lv, Chaojie Liu, Yu Chen, Lingbin Qi, Lu Wang, Yazhong Ji and Zhigang Xue Tags: Research article Source Type: research
Molecular aspects of the teratogenesis of rubella virus
Rubella or German measles is an infection caused by rubella virus (RV). Infection of children and adults is usually characterized by a mild exanthematous febrile illness. However, RV is a major cause of birth ... (Source: Biological Research)
Source: Biological Research - August 28, 2019 Category: Biomedical Science Authors: Suji George, Rajlakshmi Viswanathan and Gajanan N. Sapkal Tags: Review Source Type: research
Desiccation tolerance in the Antarctic moss Sanionia uncinata
One of the most extreme environments on our planet is the Maritime Antarctic territory, due to its low-water availability, which restricts the development of plants. Sanionia uncinata Hedw. (Amblystegiaceae), the... (Source: Biological Research)
Source: Biological Research - August 21, 2019 Category: Biomedical Science Authors: Marisol Pizarro, Rodrigo A. Contreras, Hans K öhler and Gustavo E. Zúñiga Tags: Research article Source Type: research
Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells
Free fatty acid receptor 1 (FFAR1) is G-protein coupled receptor predominantly expressed in pancreatic β-cells that is activated by a variety of free fatty acids (FFAs). Once activated, it promotes glucose-sti... (Source: Biological Research)
Source: Biological Research - August 19, 2019 Category: Biomedical Science Authors: Sulaiman K. Marafie, Eman M. Al-Shawaf, Jehad Abubaker and Hossein Arefanian Tags: Research article Source Type: research
Resveratrol reduces store-operated Ca2+ entry and enhances the apoptosis of fibroblast-like synoviocytes in adjuvant arthritis rats model via targeting ORAI1 –STIM1 complex
Resveratrol was reported to trigger the apoptosis of fibroblast-like synoviocytes in adjuvant arthritis rats but the subcellular mechanism remains unclear. Since ER stress, mitochondrial dysfunction and oxidat... (Source: Biological Research)
Source: Biological Research - August 19, 2019 Category: Biomedical Science Authors: Jinsen Lu, Jiazhao Yang, Yongshun Zheng, Shiyuan Fang and Xiaoyu Chen Tags: Research article Source Type: research
Effects of deficit irrigation and kaolin application on vegetative growth and fruit traits of two early ripening apple cultivars
Drought is one of the main serious problems for agriculture production which its intensity is increasing in many parts of the world, hence, improving water use efficiency is a main goal for sustainable agricul... (Source: Biological Research)
Source: Biological Research - August 12, 2019 Category: Biomedical Science Authors: Somayeh Faghih, Zabihollah Zamani, Reza Fatahi and Abdolmajid Liaghat Tags: Research article Source Type: research
Protein expression profiles and clinicopathologic characteristics associate with gastric cancer survival
Prognosis remains one of most crucial determinants of gastric cancer (GC) treatment, but current methods do not predict prognosis accurately. Identification of additional biomarkers is urgently required to ide... (Source: Biological Research)
Source: Biological Research - August 9, 2019 Category: Biomedical Science Authors: Wei Li, Yan Chen, Xuan Sun, Jupeng Yang, David Y. Zhang, Daguang Wang and Jian Suo Tags: Research article Source Type: research
A novel hydrazide compound exerts anti-metastatic effect against breast cancer
There are currently a number of barriers hindering the successful treatment of breast cancer, including the metastatic spread of cancer cells. In looking for new anticancer agents, we reported two novel hydraz... (Source: Biological Research)
Source: Biological Research - August 6, 2019 Category: Biomedical Science Authors: Soudeh Dehghani, Zahra Kooshafar, Ali Almasirad, Raheleh Tahmasvand, Fariborz Moayer, Ahad Muhammadnejad, Samira Shafiee and Mona Salimi Tags: Research article Source Type: research
Role of JNK and ERK1/2 MAPK signaling pathway in testicular injury of rats induced by di-N-butyl-phthalate (DBP)
Di-N-butyl-phthalate (DBP) is an endocrine disrupting substance. We investigated the adverse effect of DBP on testis of male rat and reveal its potential mechanism of MAPK signaling pathway involved this effect i... (Source: Biological Research)
Source: Biological Research - August 6, 2019 Category: Biomedical Science Authors: Hongyan Wang, Weipeng Zhou, Jing Zhang and Huan Li Tags: Research article Source Type: research
Stress and defense responses in plant secondary metabolites production
In the growth condition(s) of plants, numerous secondary metabolites (SMs) are produced by them to serve variety of cellular functions essential for physiological processes, and recent increasing evidences hav... (Source: Biological Research)
Source: Biological Research - July 29, 2019 Category: Biomedical Science Authors: Tasiu Isah Tags: Review Source Type: research
miR-29b-3p promotes progression of MDA-MB-231 triple-negative breast cancer cells through downregulating TRAF3
Breast cancer is the second common malignant cancer among females worldwide. Accumulating studies have indicated that deregulation of miRNA expression in breast cancer will contribute to tumorigenesis and form... (Source: Biological Research)
Source: Biological Research - July 26, 2019 Category: Biomedical Science Authors: Bao Zhang, Dattatrya Shetti, Conghui Fan and Kun Wei Tags: Research article Source Type: research
Berberine in combination with cisplatin induces necroptosis and apoptosis in ovarian cancer cells
Berberine (BBR), a compound extracted from a variety of medicinal herbs, has been shown multiple pharmacological effects against cancer cells of different origins. Cisplatin (DDP) is known as an effective chem... (Source: Biological Research)
Source: Biological Research - July 18, 2019 Category: Biomedical Science Authors: Li Liu, Jingyan Fan, Guihai Ai, Jie Liu, Ning Luo, Caixia Li and Zhongping Cheng Tags: Research article Source Type: research
Ropivacaine promotes apoptosis of hepatocellular carcinoma cells through damaging mitochondria and activating caspase-3 activity
Recent evidences indicated that some local anaesthetic agents played a role in inhibiting the proliferation of cancer cells; Whether ropivacaine is able to promote apoptosis of hepatocellular carcinoma (HCC) c... (Source: Biological Research)
Source: Biological Research - July 12, 2019 Category: Biomedical Science Authors: Wenting Wang, Mingyue Zhu, Zhixin Xu, Wei Li, Xu Dong, Yi Chen, Bo Lin and Mengsen Li Tags: Research article Source Type: research
