Methylation profile of the ADRB3 gene and its association with lipid profile and nutritional status in adults
Defects in DNA methylation have been shown to be associated with metabolic diseases such as obesity, dyslipidemia, and hypercholesterolemia. To analyze the methylation profile of the ADRB3 gene and correlate it w... (Source: Biological Research)
Source: Biological Research - April 6, 2019 Category: Biomedical Science Authors: Raquel Patr ícia Ataíde Lima, Marina Ramalho Ribeiro, Keylha Querino de Farias Lima, Elisama Araújo de Sena, Diego de Oliveira Costa, Rafaella Cristhine Pordeus Luna, Rayner Anderson Ferreira do Nascimento, Maria da Conceição Rodrigues Gonçalves, Ro Tags: Research Article Source Type: research
Identification and characterization of CircRNAs involved in the regulation of wheat root length
Recent studies indicate that circular RNAs (circRNAs) may play important roles in the regulation of plant growth and development. Plant roots are the main organs of nutrient and water uptake. However, whether ... (Source: Biological Research)
Source: Biological Research - April 4, 2019 Category: Biomedical Science Authors: Yanhua Xu, Yongzhe Ren, Tongbao Lin and Dangqun Cui Tags: Research article Source Type: research
MicroRNA-663 facilitates the growth, migration and invasion of ovarian cancer cell by inhibiting TUSC2
MicroRNAs (miRNAs) have emerged as the critical modulators of the tumorigenesis and tumor progression. (Source: Biological Research)
Source: Biological Research - April 3, 2019 Category: Biomedical Science Authors: Hui Hui Xie, Wen Ting Huan, Jiang Qiong Han, Wei Ru Ren and Li Hua Yang Tags: Research article Source Type: research
Plant morphology, physiological characteristics, accumulation of secondary metabolites and antioxidant activities of Prunella vulgaris L. under UV solar exclusion
Prunella vulgaris L. has been an important medicinal plant for the treatment of thyroid gland malfunction and mastitis in China for over 2000 years. There is an urgent need to select effective wavelengths for gre... (Source: Biological Research)
Source: Biological Research - April 1, 2019 Category: Biomedical Science Authors: Yuhang Chen, Xuerong Zhang, Qiaosheng Guo, Liping Cao, Qin Qin, Chen Li, Miao Zhao and Wenming Wang Tags: Research article Source Type: research
Effects of glutamine deprivation on oxidative stress and cell survival in breast cell lines
Tumourigenic cells modify metabolic pathways in order to facilitate increased proliferation and cell survival resulting in glucose- and glutamine addiction. Previous research indicated that glutamine deprivati... (Source: Biological Research)
Source: Biological Research - March 27, 2019 Category: Biomedical Science Authors: Mokgadi Violet Gwangwa, Anna Margaretha Joubert and Michelle Helen Visagie Tags: Research article Source Type: research
In vitro transplantation of spermatogonial stem cells isolated from human frozen –thawed testis tissue can induce spermatogenesis under 3-dimensional tissue culture conditions
Sperm production is one of the most complex biological processes in the body. In vitro production of sperm is one of the most important goals of researches in the field of male infertility treatment, which is ... (Source: Biological Research)
Source: Biological Research - March 27, 2019 Category: Biomedical Science Authors: Mahdi Mohaqiq, Mansoureh Movahedin, Zohreh Mazaheri and Naser Amirjannati Tags: Research article Source Type: research
Functional and transcriptomic characterization of carboplatin-resistant A2780 ovarian cancer cell line
Ovarian cancer is a significant cancer-related cause of death in women worldwide. The most used chemotherapeutic regimen is based on carboplatin (CBDCA). However, CBDCA resistance is the main obstacle to a bet... (Source: Biological Research)
Source: Biological Research - March 21, 2019 Category: Biomedical Science Authors: Tamara Viscarra, Kurt Buchegger, Ignacio Jofre, Ismael Riquelme, Louise Zanella, Michel Abanto, Alyssa C. Parker, Stephen R. Piccolo, Juan Carlos Roa, Carmen Ili and Priscilla Brebi Tags: Research article Source Type: research
Knock-down the expression of TaH2B-7D using virus-induced gene silencing reduces wheat drought tolerance
Drought is a major abiotic stress affecting global wheat (Triticum aestivum L.) production. Exploration of drought-tolerant genes is essential for the genetic improvement of drought tolerance in wheat. Previous s... (Source: Biological Research)
Source: Biological Research - March 21, 2019 Category: Biomedical Science Authors: Xinbo Wang, Yongzhe Ren, Jingjing Li, Zhiqiang Wang, Zeyu Xin and Tongbao Lin Tags: Research article Source Type: research
IRF2 –INPP4B-mediated autophagy suppresses apoptosis in acute myeloid leukemia cells
The present study aimed to investigate the underlying role of interferon-regulatory factor 2 (IRF2) –inositol polyphosphate-4-phosphatase, type-II (INPP4B) axis in the regulation of autophagy in acute myeloid l... (Source: Biological Research)
Source: Biological Research - March 15, 2019 Category: Biomedical Science Authors: Feng Zhang, Jiajia Li, Junfeng Zhu, Lin Liu, Kai Zhu, Shuang Cheng, RuDi Lv and Pingping Zhang Tags: Research Article Source Type: research
CoCl2 simulated hypoxia induce cell proliferation and alter the expression pattern of hypoxia associated genes involved in angiogenesis and apoptosis
Hypoxia microenvironment plays a crucial role during tumor progression and it tends to exhibit poor prognosis and make resistant to various conventional therapies. HIF-1 α acts as an important transcriptional r... (Source: Biological Research)
Source: Biological Research - March 15, 2019 Category: Biomedical Science Authors: Nishant Kumar Rana, Priya Singh and Biplob Koch Tags: Research Article Source Type: research
Notum attenuates HBV-related liver fibrosis through inhibiting Wnt 5a mediated non-canonical pathways
This study was to investigate anti-fibrotic effects of Notum. (Source: Biological Research)
Source: Biological Research - March 13, 2019 Category: Biomedical Science Authors: Wenting Li, Xiaolan Yu, Chuanlong Zhu, Zheng Wang, Zonghao Zhao, Yi Li and Yonghong Zhang Tags: Research Article Source Type: research
Intestinal transcriptional profiling reveals fava bean-induced immune response in DBA/1 mice
Fava beans (FBs) have long been used as food, and their principal disadvantage is derived from their haemotoxicity. We hypothesized that FB ingestion alters the intestinal gene expression pattern, thereby indu... (Source: Biological Research)
Source: Biological Research - March 1, 2019 Category: Biomedical Science Authors: Guankui Du, Man Xiao, Qiwei Zhu, Chen Zhou, Ao Wang and Wangwei Cai Tags: Research article Source Type: research
Derlin1 functions as an oncogene in cervical cancer via AKT/mTOR signaling pathway
Cervical cancer (CC) ranks third in the morbidity and mortality of female cancer around the world. Derlin1 has been found to be overexpressed in several human cancers. However, it is still unclear about its ro... (Source: Biological Research)
Source: Biological Research - February 27, 2019 Category: Biomedical Science Authors: Ling Li, Ming Liu, Zhihu Zhang, Wei Zhang, Naifu Liu, Xiugui Sheng and Ping Wei Tags: Letter to the Editor Source Type: research
Vitexin induces apoptosis through mitochondrial pathway and PI3K/Akt/mTOR signaling in human non-small cell lung cancer A549 cells
This study aimed to evaluat... (Source: Biological Research)
Source: Biological Research - February 23, 2019 Category: Biomedical Science Authors: Xiaoli Liu, Qingfeng Jiang, Huaimin Liu and Suxia Luo Tags: Research Article Source Type: research
RNA editing analysis of ATP synthase genes in the cotton cytoplasmic male sterile line H276A
Pollen development is an energy-consuming process that particularly occurs during meiosis. Low levels of adenosine triphosphate (ATP) may cause cell death, resulting in CMS (cytoplasmic male sterility). DNA se... (Source: Biological Research)
Source: Biological Research - February 6, 2019 Category: Biomedical Science Authors: Xiangjun Kong, Dongmei Liu, Jie Zheng, Aziz Khan, Bin Li, Yong Diao and Ruiyang Zhou Tags: Research article Source Type: research
