A β promotes CD38 expression in senescent microglia in Alzheimer’s disease
In Alzheimer ’s disease (AD), the neuroinflammatory response mediated by the activation of senescent microglia is closely related to energy dysmetabolism. However, the mechanism underlying the interaction betwe... (Source: Biological Research)
Source: Biological Research - March 3, 2022 Category: Biomedical Science Authors: Yiran Hu, Yan Huang, Sanli Xing, Chuan Chen, Dingzhu Shen and Jiulin Chen Tags: Research article Source Type: research
Cobalamin cbiP mutant shows decreased tolerance to low temperature and copper stress in Listeria monocytogenes
Listeria monocytogenes is a foodborne pathogen that causes listeriosis in humans. This pathogen activates multiple regulatory mechanisms in response to stress, and cobalamin biosynthesis might have a potential ro... (Source: Biological Research)
Source: Biological Research - March 2, 2022 Category: Biomedical Science Authors: L. V ásquez, A. Parra, A. M. Quesille-Villalobos, G. Gálvez, P. Navarrete, M. Latorre, M. Toro, M. González and A. Reyes-Jara Tags: Research article Source Type: research
Genetic regulation of the ompX porin of Salmonella Typhimurium in response to hydrogen peroxide stress
Salmonella Typhimurium is a Gram-negative pathogen that causes a systemic disease in mice resembling typhoid fever. During its infective cycle, S. Typhimurium is phagocytized by macrophages and proliferates insid... (Source: Biological Research)
Source: Biological Research - February 22, 2022 Category: Biomedical Science Authors: A. C. Briones, D. Lorca, A. Cofre, C. E. Cabezas, G. I. Kr üger, C. Pardo-Esté, M. S. Baquedano, C. R. Salinas, M. Espinoza, J. Castro-Severyn, F. Remonsellez, A. A. Hidalgo, E. H. Morales and C. P. Saavedra Tags: Research article Source Type: research
The OxyR and SoxR transcriptional regulators are involved in a broad oxidative stress response in Paraburkholderia xenovorans LB400
Aerobic metabolism generates reactive oxygen species that may cause critical harm to the cell. The aim of this study is the characterization of the stress responses in the model aromatic-degrading bacterium Parab... (Source: Biological Research)
Source: Biological Research - February 20, 2022 Category: Biomedical Science Authors: Valentina M éndez, Laura Rodríguez-Castro, Roberto E. Durán, Gabriel Padrón and Michael Seeger Tags: Research article Source Type: research
Neuronal GRK2 regulates microglial activation and contributes to electroacupuncture analgesia on inflammatory pain in mice
In this study,... (Source: Biological Research)
Source: Biological Research - February 3, 2022 Category: Biomedical Science Authors: Yu Chen, Yang Zhou, Xiao-Chen Li, Xue Ma, Wen-Li Mi, Yu-Xia Chu, Yan-Qing Wang and Qi-Liang Mao-Ying Tags: Research article Source Type: research
Correction to: Increased glucose metabolism in Arid5b −/− skeletal muscle is associated with the down-regulation of TBC1 domain family member 1 (TBC1D1)
(Source: Biological Research)
Source: Biological Research - February 3, 2022 Category: Biomedical Science Authors: Yuri Okazaki, Jennifer Murray, Ali Ehsani, Jessica Clark, Robert H. Whitson, Lisa Hirose, Noriyuki Yanaka and Keiichi Itakura Tags: Correction Source Type: research
Correction to: Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure
(Source: Biological Research)
Source: Biological Research - January 21, 2022 Category: Biomedical Science Authors: Karla G. Schwarz, Katherin V. Pereyra, Camilo Toledo, David C. Andrade, Hugo S. D íaz, Esteban Díaz-Jara, Domiziana Ortolani, Angélica Rios-Gallardo, Paulina Arias, Alexandra Las Heras, Ignacio Vera, Fernando C. Ortiz, Nibaldo C. Inestrosa, Carlos P. V Tags: Correction Source Type: research
Molecular structures and functional exploration of NDA family genes respond tolerant to alkaline stress in Gossypium hirsutum L.
The internal NAD(P)H dehydrogenase (NDA) gene family was a member of the NAD(P)H dehydrogenase (ND) gene family, mainly involved in the non-phosphorylated respiratory pathways in mitochondria and played crucia... (Source: Biological Research)
Source: Biological Research - January 21, 2022 Category: Biomedical Science Authors: Yapeng Fan, Yuexin Zhang, Cun Rui, Hong Zhang, Nan Xu, Jing Wang, Mingge Han, Xuke Lu, Xiugui Chen, Delong Wang, Shuai Wang, Lixue Guo, Lanjie Zhao, Hui Huang, Junjuan Wang, Liangqing Sun & hellip; Tags: Research article Source Type: research
Knockout of caspase-7 gene improves the expression of recombinant protein in CHO cell line through the cell cycle arrest in G2/M phase
Chinese hamster ovary cell line has been used routinely as a bioproduction factory of numerous biopharmaceuticals. So far, various engineering strategies have been recruited to improve the production efficienc... (Source: Biological Research)
Source: Biological Research - January 11, 2022 Category: Biomedical Science Authors: Fatemeh Safari and Bahman Akbari Tags: Research article Source Type: research
Genome-wide analysis of metallothionein gene family in maize to reveal its role in development and stress resistance to heavy metal
Maize (Zea mays L.) is a widely cultivated cereal and has been used as an optimum heavy metal phytoremediation crop. Metallothionein (MT) proteins are small, cysteine-rich, proteins that play important roles in p... (Source: Biological Research)
Source: Biological Research - January 10, 2022 Category: Biomedical Science Authors: Canhong Gao, Kun Gao, Huixian Yang, Tangdan Ju, Jingyi Zhu, Zailin Tang, Liangxia Zhao and Qingquan Chen Tags: Research article Source Type: research
Dual effects of entomopathogenic fungi on control of the pest Lobesia botrana and the pathogenic fungus Eutypella microtheca on grapevine
In this study,... (Source: Biological Research)
Source: Biological Research - December 24, 2021 Category: Biomedical Science Authors: Juan Aguilera-Sammaritano, Juan Caballero, Mar ía Deymié, Melisa Rosa, Fabio Vazquez, Delia Pappano, Bernardo Lechner and Marcia González-Teuber Tags: Research article Source Type: research
Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure
Chronic heart failure (CHF) is a global health problem. Increased sympathetic outflow, cardiac arrhythmogenesis and irregular breathing patterns have all been associated with poor outcomes in CHF. Several stud... (Source: Biological Research)
Source: Biological Research - December 24, 2021 Category: Biomedical Science Authors: Karla G. Schwarz, Katherin V. Pereyra, Camilo Toledo, David C. Andrade, Hugo S. D íaz, Esteban Díaz-Jara, Domiziana Ortolani, Angélica Rios-Gallardo, Paulina Arias, Alexandra Las Heras, Ignacio Vera, Fernando C. Ortiz, Nibaldo C. Inestrosa, Carlos P. V Tags: Research article Source Type: research
Non-coding RNAs and chromatin: key epigenetic factors from spermatogenesis to transgenerational inheritance
Cellular fate and gene expression patterns are modulated by different epigenetic factors including non-coding RNAs (ncRNAs) and chromatin organization. Both factors are dynamic throughout male germ cell differ... (Source: Biological Research)
Source: Biological Research - December 20, 2021 Category: Biomedical Science Authors: Carolina Cheuquem án and Rodrigo Maldonado Tags: Review Source Type: research
The therapeutic potential of mesenchymal stem cells in treating osteoporosis
Osteoporosis (OP), a common systemic metabolic bone disease, is characterized by low bone mass, increasing bone fragility and a high risk of fracture. At present, the clinical treatment of OP mainly involves a... (Source: Biological Research)
Source: Biological Research - December 20, 2021 Category: Biomedical Science Authors: Tianning Chen, Tieyi Yang, Weiwei Zhang and Jin Shao Tags: Review Source Type: research
Diosmetin inhibits cell proliferation and promotes apoptosis through STAT3/c-Myc signaling pathway in human osteosarcoma cells
Diosmetin is a bioflavonoid compound naturally abundant in citrus fruits. It is found to perform a variety of activities, while its antitumor property in osteosarcoma, a malignant tumor with unmet clinical tre... (Source: Biological Research)
Source: Biological Research - December 18, 2021 Category: Biomedical Science Authors: Rende Ning, Guang Chen, Run Fang, Yanhui Zhang, Wenjuan Zhao and Feng Qian Tags: Research article Source Type: research
