Analysis of the role of the interleukins in colon cancer
The role of interleukin family in colon cancer remained controversial. The purpose of this study was to investigate the association between interleukin family and colon cancer progression through bioinformatic... (Source: Biological Research)
Source: Biological Research - May 7, 2020 Category: Biomedical Science Authors: Xiyi Wei, Yuan Zhang, Zhou Yang, Yeqin Sha, Yitong Pan, Yusheng Chen and Lei Cai Tags: Research article Source Type: research

miR-185-5p response to usnic acid suppresses proliferation and regulating apoptosis in breast cancer cell by targeting Bcl2
Breast cancer is the most common cancer types among women. Recent researches have focused on determining the efficiency of alternative molecules and miRNAs in breast cancer treatment. The aim of this study was... (Source: Biological Research)
Source: Biological Research - May 4, 2020 Category: Biomedical Science Authors: Elif De ğerli, Vildan Torun and Demet Cansaran-Duman Tags: Research article Source Type: research

Knockdown of long non-coding RNA HOTAIR reverses cisplatin resistance of ovarian cancer cells through inhibiting miR-138-5p-regulated EZH2 and SIRT1
Cisplatin resistance (DDP-resistance) remains one of the major causes of poor prognosis in females with ovarian cancer. Long non-coding RNAs (lncRNAs) have been shown to participate in the regulation of cellul... (Source: Biological Research)
Source: Biological Research - April 29, 2020 Category: Biomedical Science Authors: Yun Zhang, Hao Ai, Xue Fan, Suxian Chen, Yadi Wang and Lili Liu Tags: Research article Source Type: research

Inhibition of miR-19a-3p decreases cerebral ischemia/reperfusion injury by targeting IGFBP3 in vivo and in vitro
Inflammation and apoptosis are considered to be two main factors affecting ischemic brain injury and the subsequent reperfusion damage. MiR-19a-3p has been reported to be a possible novel biomarker in ischemic... (Source: Biological Research)
Source: Biological Research - April 20, 2020 Category: Biomedical Science Authors: Zhaohui Chai, Jiangbiao Gong, Peidong Zheng and Jiesheng Zheng Tags: Research article Source Type: research

Correction to: Identification of the targets of hematoporphyrin derivative in lung adenocarcinoma using integrated network analysis
The Fig. 1b is wrongly published in the original publication of the article. The correct version of Fig. 1b is presented in this Correction. (Source: Biological Research)
Source: Biological Research - April 19, 2020 Category: Biomedical Science Authors: Hongtao Yin and Yan Yu Tags: Correction Source Type: research

Development of a small panel of SNPs to infer ancestry in Chileans that distinguishes Aymara and Mapuche components
Current South American populations trace their origins mainly to three continental ancestries, i.e. European, Amerindian and African. Individual variation in relative proportions of each of these ancestries ma... (Source: Biological Research)
Source: Biological Research - April 16, 2020 Category: Biomedical Science Authors: Ricardo A. Verdugo, Alex Di Genova, Luisa Herrera, Mauricio Moraga, M ónica Acuña, Soledad Berríos, Elena Llop, Carlos Y. Valenzuela, M. Leonor Bustamante, Dayhana Digman, Adriana Symon, Soledad Asenjo, Pamela López, Alejandro Blanco, José Suazo, Emm Tags: Research article Source Type: research

Functional and genomic characterization of three novel cell lines derived from a metastatic gallbladder cancer tumor
Gallbladder cancer (GBC) is the most common tumor of the biliary tract. The incidence of GBC shows a large geographic variability, being particularly frequent in Native American populations. In Chile, GBC repr... (Source: Biological Research)
Source: Biological Research - April 15, 2020 Category: Biomedical Science Authors: Patricia Garc ía, Carolina Bizama, Lorena Rosa, Jaime A. Espinoza, Helga Weber, Javier Cerda-Infante, Marianela Sánchez, Viviana P. Montecinos, Justo Lorenzo-Bermejo, Felix Boekstegers, Marcela Dávila-López, Francisca Alfaro, Claudia Leiva-Acevedo, Za Tags: Research article Source Type: research

LncRNA LINC00483  promotes gastric cancer development through regulating MAPK1 expression by sponging miR-490-3p
Previous studies have shown that long noncoding RNA (lncRNA) LINC00483 was aberrantly expressed in human cancers, including gastric cancer. However, the regulatory mechanism of this lncRNA in gastric cancer re... (Source: Biological Research)
Source: Biological Research - April 15, 2020 Category: Biomedical Science Authors: Min Luo and Chengbai Liang Tags: Research article Source Type: research

Mast cells-derived MiR-223 destroys intestinal barrier function by inhibition of CLDN8 expression in intestinal epithelial cells
Mast cells (MCs) have been found to play a critical role during development of inflammatory bowel disease (IBD) that characterized by dysregulation of inflammation and impaired intestinal barrier function. How... (Source: Biological Research)
Source: Biological Research - March 24, 2020 Category: Biomedical Science Authors: Musheng Li, Junhong Zhao, Meiwan Cao, Ruitao Liu, Guanhua Chen, Songyu Li, Yuanwen Xie, Jing Xie, Yang Cheng, Ling Huang, Mingmin Su, Yuxin Xu, Mingyue Zheng, Kejian Zou, Lanlan Geng, Wanfu Xu & hellip; Tags: Research article Source Type: research

MicroRNA-107 is a novel tumor suppressor targeting POU3F2 in melanoma
Melanoma is one of the major types of skin cancer. The metastatic melanoma is among the most lethal forms of malignant skin tumors. We hereby aimed to characterize a novel microRNA (miR) in the metastatic mela... (Source: Biological Research)
Source: Biological Research - March 14, 2020 Category: Biomedical Science Authors: Guizhi Zhao, Zhili Wei and Yang Guo Tags: Research article Source Type: research

Mir-30b-3p affects the migration and invasion function of ovarian cancer cells by targeting the CTHRC1 gene
The aim of this study was to investigate the effect role and mechanism of miR-30b-3p on ovarian cancer cells biological function. (Source: Biological Research)
Source: Biological Research - March 10, 2020 Category: Biomedical Science Authors: Yan Li, Jinhua Zhou, Juan Wang, Xiaoping Chen, Yan Zhu and Youguo Chen Tags: Research article Source Type: research

Studies on the cold tolerance of ratoon ‘Chaling’ common wild rice
Rice is the staple food of many people around the world. However, most rice varieties, especially widely grown indica varieties and hybrids, are sensitive to cold stress. In order to provide a basis for the utili... (Source: Biological Research)
Source: Biological Research - February 18, 2020 Category: Biomedical Science Authors: Mengliang Xu, Xiangzhen Li, Xiang Mo, Siyu Tu, Yanchun Cui and Daichang Yang Tags: Research article Source Type: research

LncRNA SNHG7/miR-34a-5p/SYVN1 axis plays a vital role in proliferation, apoptosis and autophagy in osteoarthritis
Osteoarthritis (OA) is one of the most common rheumatic diseases of which clinical symptoms includes swelling, synovitis and inflammatory pain, affect patients ’ daily life. It was reported that non-coding RNAs... (Source: Biological Research)
Source: Biological Research - February 17, 2020 Category: Biomedical Science Authors: Feng Tian, Junhu Wang, Zhanhua Zhang and Jie Yang Tags: Research article Source Type: research

CtpB is a plasma membrane copper (I) transporting P-type ATPase of Mycobacterium tuberculosis
The intracellular concentration of heavy-metal cations, such as copper, nickel, and zinc is pivotal for the mycobacterial response to the hostile environment inside macrophages. To date, copper transport media... (Source: Biological Research)
Source: Biological Research - February 13, 2020 Category: Biomedical Science Authors: Andr és León-Torres, Epifania Arango, Eliana Castillo and Carlos Y. Soto Tags: Research article Source Type: research

Linc-OIP5 in the breast cancer cells regulates angiogenesis of human umbilical vein endothelial cells through YAP1/Notch/NRP1 signaling circuit at a tumor microenvironment
LincRNAs have been revealed to be tightly associated with various tumorigeneses and cancer development, but the roles of specific lincRNA on tumor-related angiogenesis was hardly studied. Here, we aimed to inv... (Source: Biological Research)
Source: Biological Research - February 11, 2020 Category: Biomedical Science Authors: Qing Zhu, Jingchao Li, Qi Wu, Yongxia Cheng, Huizhe Zheng, Tao Zhan, Hongwei Wang, Yue Yang, Hongyan Wang, Ye Liu and Sufen Guo Tags: Research article Source Type: research