Sperm DNA integrity does play a crucial role for embryo development after ICSI, notably when good-quality oocytes from young donors are used
Based on the inconsistent literature published thus far involving infertile patients, whether intracytoplasmic sperm injection (ICSI) allows overcoming total fertilization failure due to sperm DNA fragmentatio... (Source: Biological Research)
Source: Biological Research - December 26, 2022 Category: Biomedical Science Authors: Jordi Ribas-Maynou, Sergi Novo, Marc Torres, Albert Salas-Huetos, Sergi Rovira, Marta Antich and Marc Yeste Tags: Research Article Source Type: research

Inflammation context in Alzheimer ’s disease, a relationship intricate to define
Alzheimer ’s disease (AD), the most common form of dementia, is characterized by the accumulation of amyloid β (Aβ) and hyperphosphorylated tau protein aggregates. Importantly, Aβ and tau species are able to ac... (Source: Biological Research)
Source: Biological Research - December 23, 2022 Category: Biomedical Science Authors: Catalina Novoa, Paulina Salazar, Pedro Cisternas, Camila Gherardelli, Roberto Vera-Salazar, Juan M. Zolezzi and Nibaldo C. Inestrosa Tags: Review Source Type: research

Protocol paper: kainic acid excitotoxicity-induced spinal cord injury paraplegia in Sprague –Dawley rats
Excitotoxicity-induced in vivo injury models are vital to reflect the pathophysiological features of acute spinal cord injury (SCI) in humans. The duration and concentration of chemical treatment controls the ... (Source: Biological Research)
Source: Biological Research - December 9, 2022 Category: Biomedical Science Authors: Anam Anjum, Yt Jun Cheah, Muhammad Da ’in Yazid, Muhammad Fauzi Daud, Jalilah Idris, Min Hwei Ng, Amaramalar Selvi Naicker, Ohnmar Htwe Ismail, Ramesh Kumar Athi Kumar, Geok Chin Tan, Yin Ping Wong, Mohd Kaisan Mahadi and Yogeswaran Lokanathan Tags: Research Article Source Type: research

Dynamic circadian fluctuations of glycemia in patients with type 2 diabetes mellitus
Diabetes mellitus (DM) has glucose variability that is of such relevance that the appearance of vascular complications in patients with DM has been attributed to hyperglycemic and dysglycemic events. It is kno... (Source: Biological Research)
Source: Biological Research - December 2, 2022 Category: Biomedical Science Authors: Manuel V ásquez-Muñoz, Alexis Arce-Álvarez, Cristian Álvarez, Rodrigo Ramírez-Campillo, Fernando A. Crespo, Dayana Arias, Camila Salazar-Ardiles, Mikel Izquierdo and David C. Andrade Tags: Research Article Source Type: research

Extracellular signals regulate the biogenesis of extracellular vesicles
Extracellular vesicles (EVs) are naturally released membrane vesicles that act as carriers of proteins and RNAs for intercellular communication. With various biomolecules and specific ligands, EV has represent... (Source: Biological Research)
Source: Biological Research - November 26, 2022 Category: Biomedical Science Authors: Yong Jin, Lele Ma, Wanying Zhang, Wen Yang, Qiyu Feng and Hongyang Wang Tags: Review Source Type: research

Correction: Acupuncture attenuates comorbid anxiety- and depressive-like behaviors of atopic dermatitis through modulating neuroadaptation in the brain reward circuit in mice
(Source: Biological Research)
Source: Biological Research - November 26, 2022 Category: Biomedical Science Authors: Mijung Yeom, Sora Ahn, Sun-Young Jang, Jae-Hwan Jang, Youngrye Lee, Dae-Hyun Hahm and Hi-Joon Park Tags: Correction Source Type: research

Oocyte quality assessment in marine invertebrates: a novel approach by fluorescence spectroscopy
The assessment of oocyte quality is, nowadays, a major challenge in aquaculture, oocyte cryopreservation, and environmental science. Oocyte quality is a determining factor in fertilization and embryo developme... (Source: Biological Research)
Source: Biological Research - November 12, 2022 Category: Biomedical Science Authors: Alessandra Gallo, Maria Consiglia Esposito, Raffaele Boni and Elisabetta Tosti Tags: Research article Source Type: research

Utility of melatonin in mitigating ionizing radiation-induced testis injury through synergistic interdependence of its biological properties
Ionizing radiations (IR) have widespread useful applications in our daily life; however, they have unfavorable effects on reproductive health. Maintaining testicular health following IR exposure is an importan... (Source: Biological Research)
Source: Biological Research - November 4, 2022 Category: Biomedical Science Authors: Maggie E. Amer, Azza I. Othman, Hajer Mohammed Abozaid and Mohamed A. El-Missiry Tags: Research article Source Type: research

The production of the first functional antibody mimetic in higher plants: the chloroplast makes the DARPin G3 for HER2 imaging in oncology
Designed mimetic molecules are attractive tools in biopharmaceuticals and synthetic biology. They require mass and functional production for the assessment of upcoming challenges in the near future. The DARPin... (Source: Biological Research)
Source: Biological Research - October 23, 2022 Category: Biomedical Science Authors: Maryam Ehsasatvatan, Bahram Baghban Kohnehrouz, Ashraf Gholizadeh, Hamideh Ofoghi and Dariush Shanehbandi Tags: Research article Source Type: research

Genetically modified organisms: adapting regulatory frameworks for evolving genome editing technologies
Genetic modification of living organisms has been a prosperous activity for research and development of agricultural, industrial and biomedical applications. Three decades have passed since the first genetical... (Source: Biological Research)
Source: Biological Research - October 20, 2022 Category: Biomedical Science Authors: Pablo Rozas, Eduardo I. Kessi-P érez and Claudio Martínez Tags: Review Source Type: research

Immature rat testis sustained long-term development using an integrative model
In this study... (Source: Biological Research)
Source: Biological Research - October 4, 2022 Category: Biomedical Science Authors: Yubo Ma, Juan Chen, Hecheng Li, Fangshi Xu, Tie Chong, Ziming Wang and Liandong Zhang Tags: Research article Source Type: research

Melanoma stem cells promote metastasis via exosomal miR-1268a inactivation of autophagy
Metastatic melanoma has a high mortality rate and poor survival. This is associated with efficient metastatic colonization, but the underlying mechanisms remain elusive. Communication between cancer stem cells... (Source: Biological Research)
Source: Biological Research - October 1, 2022 Category: Biomedical Science Authors: Xiaoshuang Li, Doudou Liu, Hao Chen, Bin Zeng, Qiting Zhao, Yuhan Zhang, Yuting Chen, Jianyu Wang and H. Rosie Xing Tags: Research article Source Type: research

Acupuncture attenuates comorbid anxiety- and depressive-like behaviors of atopic dermatitis through modulating neuroadaptation in the brain reward circuit in mice
Atopic dermatitis (AD) is highly comorbid with negative emotions such as anxiety and depression. Although acupuncture has demonstrated efficacy in AD, its influence on comorbid anxiety and depression remains u... (Source: Biological Research)
Source: Biological Research - September 10, 2022 Category: Biomedical Science Authors: Mijung Yeom, Sora Ahn, Sun-Young Jang, Jae-Hwan Jang, Youngrye Lee, Dae-Hyun Hahm and Hi-Joon Park Tags: Research article Source Type: research

Structure and character analysis of cotton response regulator genes family reveals that GhRR7 responses to draught stress
Cytokinin signal transduction is mediated by a two-component system (TCS). Two-component systems are utilized in plant responses to hormones as well as to biotic and abiotic environmental stimuli. In plants, resp... (Source: Biological Research)
Source: Biological Research - August 16, 2022 Category: Biomedical Science Authors: Lanjie Zhao, Lixue Guo, Xuke Lu, Waqar Afzal Malik, Yuexin Zhang, Jing Wang, Xiugui Chen, Shuai Wang, Junjuan Wang, Delong Wang and Wuwei Ye Tags: Research article Source Type: research

Impact of inactivated SARS-CoV-2 vaccination on embryo ploidy: a retrospective cohort study of 133 PGT-A cycles in China
Unsubstantiated concerns have been raised on the potential correlation between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination and infertility, leading to vaccine hesitancy in reproduc... (Source: Biological Research)
Source: Biological Research - August 12, 2022 Category: Biomedical Science Authors: Jialyu Huang, Leizhen Xia, Lifeng Tian, Hancheng Fan, Dingfei Xu, Xiaoyan Ai, Xingwu Wu, Jia Chen, Genbao Xing, Lingling Huang, Huijun Zuo, Jia Chen, Mengxi Li, Ke Zhang, Peipei Liu, Jiaying Lin & hellip; Tags: Research article Source Type: research