Mild poikilocapnic hypoxia increases very low frequency haemoglobin oxygenation oscillations in prefrontal cortex
The aim of the study was to investigate the effect of mild cerebral hypoxia on haemoglobin oxygenation (HbO2), cerebrospinal fluid dynamics and cardiovascular physiology. To achieve this goal, four signals were r... (Source: Biological Research)
Source: Biological Research - December 14, 2021 Category: Biomedical Science Authors: Agnieszka Gruszecka, Monika Waskow, Marta A. Malkiewicz, J. Patrick Neary, Jyotpal Singh, Taylor Teckchandani, Gregory P. Kratzig, Magdalena Wszedybyl-Winklewska, Andrzej F. Frydrychowski, Jacek Rumi ński, Natalia Głowacka, Piotr Lass, Pawel J. Winklews Tags: Research article Source Type: research
Increased susceptibility of cystic fibrosis airway epithelial cells to ferroptosis
Defective chloride transport in airway epithelial cells (AECs) and the associated lung disease are the main causes of morbidity and early mortality in cystic fibrosis (CF). Abnormal airway iron homeostasis and... (Source: Biological Research)
Source: Biological Research - December 13, 2021 Category: Biomedical Science Authors: Pramila Maniam, Ama-Tawiah Essilfie, Murugan Kalimutho, Dora Ling, David M. Frazer, Simon Phipps, Gregory J. Anderson and David W. Reid Tags: Research article Source Type: research
The role of vulpinic acid as a natural compound in the regulation of breast cancer-associated miRNAs
Breast cancer is the most frequently diagnosed cancer, and no effective treatment solution has yet been found. The number of studies based on the research of novel natural compounds in the treatment of breast ... (Source: Biological Research)
Source: Biological Research - November 7, 2021 Category: Biomedical Science Authors: Demet Cansaran-Duman, Sevcan Yang ın and Betül Çolak Tags: Research article Source Type: research
Genome-wide identification and characteristic analysis of the downstream melatonin metabolism gene GhM2H in Gossypium hirsutum L.
Melatonin 2-hydroxylase (M2H) is the first enzyme in the catabolism pathway of melatonin, which catalyzes the production of 2-hydroxymelatonin (2-OHM) from melatonin. The content of 2-hydroxymelatonin in plant... (Source: Biological Research)
Source: Biological Research - November 4, 2021 Category: Biomedical Science Authors: Yuexin Zhang, Jing Wang, Xiugui Chen, Xuke Lu, Delong Wang, Junjuan Wang, Shuai Wang, Chao Chen, Lixue Guo, Waqar Afzal Malik, Yapeng Fan, Cun Rui, Ruifeng Cui, Qinqin Wang, Yuqian Lei and Wuwei Ye Tags: Research article Source Type: research
Allergens of the urushiol family promote mitochondrial dysfunction by inhibiting the electron transport at the level of cytochromes b and chemically modify cytochrome c1
Urushiols are pro-electrophilic haptens that cause severe contact dermatitis mediated by CD8+ effector T-cells and downregulated by CD4+ T-cells. However, the molecular mechanism by which urushiols stimulate inna... (Source: Biological Research)
Source: Biological Research - October 28, 2021 Category: Biomedical Science Authors: Rodrigo Pacheco, Sergio A. Quezada, Alexis M. Kalergis, Mar ía Inés Becker, Jorge Ferreira and Alfredo E. De Ioannes Tags: Research article Source Type: research
The SREBP (Sterol Regulatory Element-Binding Protein) pathway: a regulatory bridge between carotenogenesis and sterol biosynthesis in the carotenogenic yeast Xanthophyllomyces dendrorhous
Xanthophyllomyces dendrorhous is a basidiomycete yeast that naturally produces the red –orange carotenoid astaxanthin, which has remarkable antioxidant properties. The biosynthesis of carotenoids and sterols share... (Source: Biological Research)
Source: Biological Research - October 26, 2021 Category: Biomedical Science Authors: Melissa G ómez, Marcelo Baeza, Víctor Cifuentes and Jennifer Alcaíno Tags: Review Source Type: research
Antisense noncoding mitochondrial RNA-2 gives rise to miR-4485-3p by Dicer processing in vitro
The antisense noncoding mitochondrial RNAs (ASncmtRNAs) derive from the mitochondrial 16S gene. Knockdown of these transcripts with chemically-modified antisense oligonucleotides induces proliferative arrest, ... (Source: Biological Research)
Source: Biological Research - October 19, 2021 Category: Biomedical Science Authors: Nicole Farf án, Nicole Sanhueza, Macarena Briones, Luis O. Burzio and Verónica A. Burzio Tags: Short report Source Type: research
Heart rate and cardiac autonomic responses to concomitant deep breathing, hand grip exercise, and circulatory occlusion in healthy young adult men and women
Deep breathing (DB) and handgrip (HG) exercise -with and without circulatory occlusion (OC) in muscle-, have been shown to have beneficial effects on cardiovascular function; however, the combination of these ... (Source: Biological Research)
Source: Biological Research - September 26, 2021 Category: Biomedical Science Authors: David C. Andrade, Claudia Melipillan, Camilo Toledo, Ang élica Rios-Gallardo, Noah J. Marcus, Fernando C. Ortiz, Gonzalo Martinez, Paula Muñoz Venturelli and Rodrigo Del Rio Tags: Research article Source Type: research
Structural and functional alterations in heart and skeletal muscle following severe TAC in mice: impact of moderate exercise training
Heart failure (HF) is the leading cause of death in western countries. Cardiac dysfunction is accompanied by skeletal alterations resulting in muscle weakness and fatigue. Exercise is an accepted interventiona... (Source: Biological Research)
Source: Biological Research - September 19, 2021 Category: Biomedical Science Authors: Julia B öttner, Sarah Werner, Volker Adams, Sarah Knauth, Angela Kricke, Holger Thiele and Petra Büttner Tags: Research article Source Type: research
miR-146a-5p-mediated suppression on trophoblast cell progression and epithelial-mesenchymal transition in preeclampsia
This study aims to identify the effect of miR-146a-5p on trophoblast cell invasion as well as the mechanism in preeclampsia (PE). (Source: Biological Research)
Source: Biological Research - September 13, 2021 Category: Biomedical Science Authors: Pingping Peng, Huamei Song, Chenghong Xie, Wenfei Zheng, Huigai Ma, Dandan Xin, Jingqiong Zhan, Xiaoqing Yuan, Aihua Chen, Jing Tao and Jufang Qin Tags: Research article Source Type: research
Retraction Note to: LncRNA HCG11 regulates proliferation and apoptosis of vascular smooth muscle cell through targeting miR ‑144‑3p/FOXF1 axis in atherosclerosis
(Source: Biological Research)
Source: Biological Research - September 9, 2021 Category: Biomedical Science Authors: Yi Liu, Xiyun Cui, Cong Wang and Sihai Zhao Tags: Retraction Note Source Type: research
Effects of foliar spray of agricultural grade mineral oil in springtime, in combination with potassium and calcium sulfates on the phenological and biophysical indices of clusters, and foliar nutritional levels in grapevine (Vitis vinifera L.) cv. Sultana (Id. Thompson seedless, Sultanina)
Improving the nutritional condition of grapevine in spring to regulate bloom, fruit set, and yield is among the management goals of vineyards. (Source: Biological Research)
Source: Biological Research - September 8, 2021 Category: Biomedical Science Authors: Rouhollah Karimi, Abbas Saberi and Ali Khadivi Tags: Research article Source Type: research
Demethylzeylasteral (T-96) initiates extrinsic apoptosis against prostate cancer cells by inducing ROS-mediated ER stress and suppressing autophagic flux
Demethylzeylasteral (T-96) is a pharmacologically active triterpenoid monomer extracted from Tripterygium wilfordii Hook F (TWHF) that has been reported to exhibit anti-neoplastic effects against several types of... (Source: Biological Research)
Source: Biological Research - September 6, 2021 Category: Biomedical Science Authors: Dong-lin Yang, Ya-jun Zhang, Liu-jun He, Chun-sheng Hu, Li-xia Gao, Jiu-hong Huang, Yan Tang, Jie Luo, Dian-yong Tang and Zhong-zhu Chen Tags: Research article Source Type: research
Association between single-nucleotide polymorphisms in miRNA and breast cancer risk: an updated review
Breast cancer (BC), a heterogeneous, aggressive illness with high mortality, is essentially a genomic disease. While the high-penetrance genes BRCA1 and BRCA2 play important roles in tumorigenesis, moderate- and ... (Source: Biological Research)
Source: Biological Research - August 28, 2021 Category: Biomedical Science Authors: Trinidad Arancibia, Sebastian Morales-Pison, Edio Maldonado and Lilian Jara Tags: Review Source Type: research
Electroacupuncture suppresses glucose metabolism and GLUT-3 expression in medial prefrontal cortical in rats with neuropathic pain
Accumulating evidence has demonstrated that the electroacupuncture (EA) stimulation could effectively alleviate neuropathic pain. The medial prefrontal cortex (mPFC) is a vital part of the cortical representat... (Source: Biological Research)
Source: Biological Research - August 6, 2021 Category: Biomedical Science Authors: Menghong Jiang, Xiaomei Chen, Liangping Zhang, Weiting Liu, Xiangmei Yu, Zhifu Wang and Meifeng Zheng Tags: Review Source Type: research
