Allergens of the urushiol family promote mitochondrial dysfunction by inhibiting the electron transport at the level of cytochromes b and chemically modify cytochrome c1

Urushiols are pro-electrophilic haptens that cause severe contact dermatitis mediated by CD8+ effector T-cells and downregulated by CD4+ T-cells. However, the molecular mechanism by which urushiols stimulate inna...

Source: Biological Research - October 28, 2021 Category: Biomedical Science Authors: Rodrigo Pacheco, Sergio A. Quezada, Alexis M. Kalergis, Mar ía Inés Becker, Jorge Ferreira and Alfredo E. De Ioannes Tags: Research article Source Type: research