Novel mechanisms underlying anti-polycystic ovary like syndrome effects of electroacupuncture in rats: suppressing SREBP1 to mitigate insulin resistance, mitochondrial dysfunction and oxidative stress
Acupuncture, a therapy of traditional Chinese medicine, is confirmed to exert the therapeutic action on polycystic ovary syndrome (PCOS). However, the detailed therapeutic mechanisms of acupuncture in PCOS rem... (Source: Biological Research)
Source: Biological Research - October 27, 2020 Category: Biomedical Science Authors: Yan Peng, Xinming Yang, Xi Luo, Chunhong Liu, Xia Cao, Hongyan Wang and Liyuan Guo Tags: Research article Source Type: research
LncRNA OIP5-AS1 upregulates snail expression by sponging miR-34a to promote ovarian carcinoma cell invasion and migration
This study aimed to investigate the role of... (Source: Biological Research)
Source: Biological Research - October 22, 2020 Category: Biomedical Science Authors: Xingzhi Jiang, Zhongxue Ye, Yafen Jiang, Wen Yu and Qian Fang Tags: Research article Source Type: research
Daphnetin inhibits proliferation and inflammatory response in human HaCaT keratinocytes and ameliorates imiquimod-induced psoriasis-like skin lesion in mice
Psoriasis is a common chronic inflammatory skin disease. Keratinocytes hyperproliferation and excessive inflammatory response contribute to psoriasis pathogenesis. The agents able to attenuate keratinocytes hy... (Source: Biological Research)
Source: Biological Research - October 20, 2020 Category: Biomedical Science Authors: Jintao Gao, Fangru Chen, Huanan Fang, Jing Mi, Qi Qi and Mengjuan Yang Tags: Research article Source Type: research
Evaluating the clinical significance of SHMT2 and its co-expressed gene in human kidney cancer
Kidney cancer is one of the most common cancers in the world. It is necessary to clarify its underlying mechanism and find its prognostic biomarkers. Current studies showed that SHMT2 may be participated in se... (Source: Biological Research)
Source: Biological Research - October 16, 2020 Category: Biomedical Science Authors: Huan Wang, Tie Chong, Bo-Yong Li, Xiao-San Chen and Wen-Bo Zhen Tags: Original paper Source Type: research
Fate of nitrogen in agriculture and environment: agronomic, eco-physiological and molecular approaches to improve nitrogen use efficiency
Nitrogen is the main limiting nutrient after carbon, hydrogen and oxygen for photosynthetic process, phyto-hormonal, proteomic changes and growth-development of plants to complete its lifecycle. Excessive and ... (Source: Biological Research)
Source: Biological Research - October 16, 2020 Category: Biomedical Science Authors: Muhammad Anas, Fen Liao, Krishan K. Verma, Muhammad Aqeel Sarwar, Aamir Mahmood, Zhong-Liang Chen, Qiang Li, Xu-Peng Zeng, Yang Liu and Yang-Rui Li Tags: Review Source Type: research
Increased glucose metabolism in Arid5b −/− skeletal muscle is associated with the down-regulation of TBC1 domain family member 1 (TBC1D1)
Skeletal muscle has an important role in regulating whole-body energy homeostasis, and energy production depends on the efficient function of mitochondria. We demonstrated previously that AT-rich interactive d... (Source: Biological Research)
Source: Biological Research - October 6, 2020 Category: Biomedical Science Authors: Yuri Okazaki, Jennifer Murray, Ali Ehsani, Jessica Clark, Robert H. Whitson, Lisa Hirose, Noriyuki Yanaka and Keiichi Itakura Tags: Research article Source Type: research
LncRNA HCG11 regulates proliferation and apoptosis of vascular smooth muscle cell through targeting miR-144-3p/FOXF1 axis in atherosclerosis
Atherosclerosis (AS) is the main pathological basis of coronary heart disease, cerebral infarction and peripheral vascular disease, which seriously endanger people ’s life and health. In recent years, long non-... (Source: Biological Research)
Source: Biological Research - October 2, 2020 Category: Biomedical Science Authors: Yi Liu, Xiyun Cui, Cong Wang and Sihai Zhao Tags: Research article Source Type: research
Inhibition of phospholipase D2 augments histone deacetylase inhibitor-induced cell death in breast cancer cells
Histone deacetylase (HDAC) inhibitors are promising anticancer drugs but their effect on tumor treatment has been disappointing mainly due to the acquisition of HDAC inhibitor resistance. However, the mechanis... (Source: Biological Research)
Source: Biological Research - October 1, 2020 Category: Biomedical Science Authors: Won Chan Hwang, Dong Woo Kang, Youra Kang, Younghoon Jang, Jung-Ae Kim and Do Sik Min Tags: Research article Source Type: research
MiR-128 suppresses metastatic capacity by targeting metadherin in breast cancer cells
Breast cancer, the most common cancer in women worldwide, causes the vast majority of cancer-related deaths. Undoubtedly, tumor metastasis and recurrence are responsible for more than 90 percent of these death... (Source: Biological Research)
Source: Biological Research - September 29, 2020 Category: Biomedical Science Authors: Danxia Cao, Han Zhu, Qian Zhao, Jianming Huang, Cixiang Zhou, Jianrong He and Yongjun Liang Tags: Research article Source Type: research
Tumor suppressive function of Matrin 3 in the basal-like breast cancer
Basal-like breast cancer (BLBC) or triple-negative breast cancer (TNBC) is an aggressive and highly metastatic subtype of human breast cancer. The present study aimed to elucidate the potential tumor-suppressi... (Source: Biological Research)
Source: Biological Research - September 25, 2020 Category: Biomedical Science Authors: Jaehyuk Yang, Seung Jun Lee, Yongseok Kwon, Li Ma and Jongchan Kim Tags: Research article Source Type: research
REC8 suppresses tumor angiogenesis by inhibition of NF- κB-mediated vascular endothelial growth factor expression in gastric cancer cells
Tumor angiogenesis is an essential event for tumor growth and metastasis. It has been showed that REC8, a component of the meiotic cohesion complex, played a vital role in Epithelial-Mesenchymal Transition (EM... (Source: Biological Research)
Source: Biological Research - September 21, 2020 Category: Biomedical Science Authors: Miao Liu, Wanfu Xu, Mingmin Su and Pingsheng Fan Tags: Research article Source Type: research
The roles of miRNA, lncRNA and circRNA in the development of osteoporosis
Osteoporosis is a common metabolic bone disease, influenced by genetic and environmental factors, that increases bone fragility and fracture risk and, therefore, has a serious adverse effect on the quality of ... (Source: Biological Research)
Source: Biological Research - September 16, 2020 Category: Biomedical Science Authors: Yang Yang, Wang Yujiao, Wang Fang, Yuan Linhui, Guo Ziqi, Wei Zhichen, Wang Zirui and Wang Shengwang Tags: Review Source Type: research
Palmatine ameliorates high fat diet induced impaired glucose tolerance
The impaired glucose tolerance (IGT) is a representative prediabetes characterized by defective glucose homeostasis, and palmatine (PAL) is a natural isoquinoline alkaloid with multiple pharmacological effects... (Source: Biological Research)
Source: Biological Research - September 14, 2020 Category: Biomedical Science Authors: Xusheng Tian, Yukun Zhang, Han Li, Yunfeng Li, Ning Wang, Wei Zhang and Boyan Ma Tags: Research article Source Type: research
LncRNA SNHG14 promotes OGD/R-induced neuron injury by inducing excessive mitophagy via miR-182-5p/BINP3 axis in HT22 mouse hippocampal neuronal cells
Long non-coding RNA (lncRNA) small nucleolar RNA host gene 14 (SNHG14) is associated with cerebral ischemia –reperfusion (CI/R) injury. This work aims to explore the role of SNHG14 in CI/R injury. (Source: Biological Research)
Source: Biological Research - September 10, 2020 Category: Biomedical Science Authors: Zexiang Deng, Hao Ou, Fei Ren, Yujiao Guan, Ye Huan, Hongwei Cai and Bei Sun Tags: Research article Source Type: research
Altered thalamic neurotransmitters metabolism and functional connectivity during the development of chronic constriction injury induced neuropathic pain
To investigate the thalamic neurotransmitters and functional connections in the development of chronic constriction injury (CCI)-induced neuropathic pain. (Source: Biological Research)
Source: Biological Research - August 26, 2020 Category: Biomedical Science Authors: Zhifu Wang, Sheng Huang, Xiangmei Yu, Long Li, Minguang Yang, Shengxiang Liang, Weilin Liu and Jing Tao Tags: Research article Source Type: research
