The comprehensive detection of miRNA, lncRNA, and circRNA in regulation of mouse melanocyte and skin development
Pigmentation development, is a complex process regulated by many transcription factors during development. With the development of the RNA sequencing (RNA-seq), non-coding RNAs, such as miRNAs, lncRNAs, and ci... (Source: Biological Research)
Source: Biological Research - February 3, 2020 Category: Biomedical Science Authors: Zhiwei Zhu, Yueyue Ma, Yuan Li, Pengfei Li, Zhixue Cheng, Huifeng Li, Lihuan Zhang and Zhongwei Tang Tags: Research article Source Type: research
Comparison of protein profiles of the pellicle, gingival crevicular fluid, and saliva: possible origin of pellicle proteins
In this study, protein compositions of the pellicle, gingival crevicular fluid... (Source: Biological Research)
Source: Biological Research - January 15, 2020 Category: Biomedical Science Authors: Hibiki Odanaka, Takashi Obama, Naoko Sawada, Marika Sugano, Hiroyuki Itabe and Matsuo Yamamoto Tags: Research article Source Type: research
Disentangling the genetic bases of Saccharomyces cerevisiae nitrogen consumption and adaptation to low nitrogen environments in wine fermentation
The budding yeast Saccharomyces cerevisiae has been considered for more than 20 years as a premier model organism for biological sciences, also being the main microorganism used in wide industrial applications, l... (Source: Biological Research)
Source: Biological Research - January 9, 2020 Category: Biomedical Science Authors: Eduardo I. Kessi-P érez, Jennifer Molinet and Claudio Martínez Tags: Review Source Type: research
SNHG1 promotes MPP+-induced cytotoxicity by regulating PTEN/AKT/mTOR signaling pathway in SH-SY5Y cells via sponging miR-153-3p
Long non-coding RNA small molecule RNA host gene 1 (SNHG1) was previously identified to be relevant with Parkinson ’s disease (PD) pathogenesis. This work aims to further elucidate the regulatory networks of SN... (Source: Biological Research)
Source: Biological Research - January 6, 2020 Category: Biomedical Science Authors: Jun Zhao, Lijiao Geng, Yong Chen and Chunfang Wu Tags: Research article Source Type: research
LncRNA LINC00460 promotes the papillary thyroid cancer progression by regulating the LINC00460/miR-485-5p/Raf1 axis
Papillary thyroid cancer (PTC) is the most common malignancy of all thyroid cancers. LncRNA LINC00460 has been proved to play roles in the oncogenesis and progression of various tumors, including papillary thy... (Source: Biological Research)
Source: Biological Research - December 23, 2019 Category: Biomedical Science Authors: Guangjun Li and Qingli Kong Tags: Research article Source Type: research
RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXR α/SREBP1c pathway
Recent studies have confirmed that RASAL1 has an antitumor effect in many cancers, but its functional role and the molecular mechanism underlying in colon cancer has not been investigated. (Source: Biological Research)
Source: Biological Research - December 17, 2019 Category: Biomedical Science Authors: Guangchuan Wang, Zhen Li, Xiao Li, Chunqing Zhang and Lipan Peng Tags: Research article Source Type: research
FOXC2-AS1 regulates phenotypic transition, proliferation and migration of human great saphenous vein smooth muscle cells
In varicose veins, vascular smooth muscle cells (VSMCs) often shows phenotypic transition and abnormal proliferation and migration. Evidence suggests the FOXC2 –Notch pathway may be involved in the pathogenesis... (Source: Biological Research)
Source: Biological Research - December 4, 2019 Category: Biomedical Science Authors: Chuang Zhang, Huixiang Li and Xueli Guo Tags: Research article Source Type: research
Long non-coding RNA MALAT1 enhances the apoptosis of cardiomyocytes through autophagy inhibition by regulating TSC2-mTOR signaling
Our previous study showed that knockdown of long noncoding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) attenuated myocardial apoptosis in mouse acute myocardial infarction (AMI... (Source: Biological Research)
Source: Biological Research - November 29, 2019 Category: Biomedical Science Authors: Hao Hu, Jiawei Wu, Xiaofan Yu, Junling Zhou, Hua Yu and Likun Ma Tags: Research article Source Type: research
Gramicidin inhibits human gastric cancer cell proliferation, cell cycle and induced apoptosis
Gastric cancer is a common malignant tumor with high morbidity and mortality worldwide, which seriously affects human health. Gramicidin is a short peptide antibiotic which could be used for treating infection... (Source: Biological Research)
Source: Biological Research - November 25, 2019 Category: Biomedical Science Authors: Tingting Chen, Yong Wang, Yang Yang, Kaikai Yu, Xiangliao Cao, Fang Su, Huanbai Xu, Yongde Peng, Yudong Hu, Feng Qian and Zishu Wang Tags: Research article Source Type: research
PDIL1-2 can indirectly and negatively regulate expression of the AGPL1 gene in bread wheat
ADP-glucose pyrophosphorylase (AGPase), the key enzyme in plant starch biosynthesis, is a heterotetramer composed of two identical large subunits and two identical small subunits. AGPase has plastidial and cyt... (Source: Biological Research)
Source: Biological Research - November 7, 2019 Category: Biomedical Science Authors: Jie Dong, Yongxing Zheng, Yihan Fu, Jinxi Wang, Shasha Yuan, Yonghua Wang, Qidi Zhu, Xingqi Ou, Gezi Li and Guozhang Kang Tags: Research article Source Type: research
Epanorin, a lichen secondary metabolite, inhibits proliferation of MCF-7 breast cancer cells
Epanorin (EP) is a secondary metabolite of the Acarospora lichenic species. EP has been found in lichenic extracts with antimicrobial activity, and UV-absorption properties have been described for closely related... (Source: Biological Research)
Source: Biological Research - October 10, 2019 Category: Biomedical Science Authors: Juan Palacios-Moreno, Cecilia Rubio, Wanda Quilhot, M. Fernanda Cavieres, Eduardo de la Pe ña, Natalia V. Quiñones, Hugo Díaz, Flavio Carrión, Carlos F. Henríquez-Roldán and Caroline R. Weinstein-Oppenheimer Tags: Research article Source Type: research
IcarisideII facilitates the differentiation of ADSCs to SCs via let-7i/STAT3 axis to preserve erectile function
IcarisideII (ICAII) could promote the differentiation of adipose tissue-derived stem cells (ADSCs) to Schwann cells (SCs), leading to improvement of erectile function (EF) and providing a realistic therapeutic... (Source: Biological Research)
Source: Biological Research - October 3, 2019 Category: Biomedical Science Authors: Pingyu Ge, Yinxue Guo and Jun Shen Tags: Research article Source Type: research
Neuroprotective effects of an Nrf2 agonist on high glucose-induced damage in HT22 cells
Oxidative stress is the hallmark of diabetic encephalopathy, which may be caused by hyperglycaemic toxicity. We aimed to discover pharmacologic targets to restore redox homeostasis. We identified the transcrip... (Source: Biological Research)
Source: Biological Research - September 21, 2019 Category: Biomedical Science Authors: Jiangpei Zhao, Lerong Liu, Xia Li, Lingxiao Zhang, Jing Lv, Xueli Guo, Hui Chen and Tongfeng Zhao Tags: Research article Source Type: research
LncRNA XIST promotes extracellular matrix synthesis, proliferation and migration by targeting miR-29b-3p/COL1A1 in human skin fibroblasts after thermal injury
This study aimed to investigate the role of lncRNA X-inactive specific transcript (XIST) in huma... (Source: Biological Research)
Source: Biological Research - September 20, 2019 Category: Biomedical Science Authors: Wei Cao and Youping Feng Tags: Research article Source Type: research
Spores of Beauveria bassiana and Trichoderma lignorum as a bioinsecticide for the control of Atta cephalotes
The leafcutter ant (Atta cephalotes) is associated with losses in the agricultural sector, due to its defoliating activity; for its control, biological, mechanical and chemical methods have been developed, the la... (Source: Biological Research)
Source: Biological Research - September 17, 2019 Category: Biomedical Science Authors: Fabian Felipe Fernandez Daza, Ginna Rodriguez Roman, Marino Valencia Rodriguez, Ivan Andres Gonzalez Vargas, Heiber Cardenas Heano, Marney Pascoli Cereda and Raul Alberto Cuervo Mulet Tags: Research article Source Type: research
