TFAP2C increases cell proliferation by downregulating GADD45B and PMAIP1 in non-small cell lung cancer cells
Non-small cell lung cancer (NSCLC) is one of the leading causes of death in the world. NSCLC diagnosed at an early stage can be highly curable with a positive prognosis, but biomarker limitations make it diffi... (Source: Biological Research)
Source: Biological Research - July 11, 2019 Category: Biomedical Science Authors: Hyunhee Do, Dain Kim, JiHoon Kang, Beomseok Son, Danbi Seo, HyeSook Youn, BuHyun Youn and Wanyeon Kim Tags: Research article Source Type: research
Psoralen inhibits malignant proliferation and induces apoptosis through triggering endoplasmic reticulum stress in human SMMC7721 hepatoma cells
Psoralen is a coumarin-like and coumarin-related benzofuran glycoside, which is a commonly used traditional Chinese medicine to treat patients with kidney and spleen-yang deficiency symptom. Psoralen has been ... (Source: Biological Research)
Source: Biological Research - July 5, 2019 Category: Biomedical Science Authors: Xiaomin Wang, Peike Peng, Zhiqiang Pan, Zhaoqin Fang, Wenli Lu and Xiaomei Liu Tags: Research article Source Type: research
LncRNA CASC11 promotes the cervical cancer progression by activating Wnt/beta-catenin signaling pathway
Studies have shown that cancer susceptibility candidate 11 (CASC11), a newly discovered long non-coding RNA (lncRNA), was aberrantly overexpressed in hepatic carcinoma, gastric cancer and colorectal cancer. Howev... (Source: Biological Research)
Source: Biological Research - June 29, 2019 Category: Biomedical Science Authors: Wenchan Hsu, Lifen Liu, Xin Chen, Ying Zhang and Weipei Zhu Tags: Research article Source Type: research
The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells
Long non-coding RNA H19 (H19) plays an important role by regulating protein expression in different tissues and organs of the body. However, whether H19 induces hypoxia/reoxygenation (h/R) injury via increase ... (Source: Biological Research)
Source: Biological Research - June 13, 2019 Category: Biomedical Science Authors: Chao Cui, Zhiyu Li and Dequan Wu Tags: Short report Source Type: research
Effects of DACT1 methylation status on invasion and metastasis of nasopharyngeal carcinoma
The purpose of the present study was to investigate the role of the methylation status of the DACT1 gene on the invasion and metastasis of nasopharyngeal carcinoma cells. (Source: Biological Research)
Source: Biological Research - June 10, 2019 Category: Biomedical Science Authors: Ju-Hong Yang, Lie-Kun Lin and Song Zhang Tags: Research article Source Type: research
Chronic prostatitis alters the prostatic microenvironment and accelerates preneoplastic lesions in C57BL/6 mice
The objective of this study was to examine how chronic inflammation results in a prostatic microenviron... (Source: Biological Research)
Source: Biological Research - May 14, 2019 Category: Biomedical Science Authors: Yong Gao, Lijuan Wei, Chenbang Wang, Yuanjie Huang, Weidong Li, Tianyu Li, Chaohua Mo, Huali Qin, Xiaoge Zhong, Yun Wang, Aihua Tan, Zengnan Mo, Yonghua Jiang and Yanling Hu Tags: Research article Source Type: research
Effect of carbamylated erythropoietin on neuronal apoptosis in fetal rats during intrauterine hypoxic-ischemic encephalopathy
Hypoxic-ischemic encephalopathy (HIE) is a common disease that occurs during the perinatal period. The primary cause of neonatal HIE is related to fetal intrauterine anoxia. Carbamylated erythropoietin (CEPO),... (Source: Biological Research)
Source: Biological Research - May 13, 2019 Category: Biomedical Science Authors: Min Diao, Yi Qu, Hui Liu, Yushan Ma and Xuemei Lin Tags: Research article Source Type: research
CXCL8(3 –72) K11R/G31P protects against sepsis-induced acute kidney injury via NF-κB and JAK2/STAT3 pathway
Acute kidney injury (AKI), which is mainly caused by sepsis, has high morbidity and mortality rates. CXCL8(3 –72) K11R/G31P (G31P) can exert therapeutic effect on inflammatory diseases and malignancies. We aimed t... (Source: Biological Research)
Source: Biological Research - May 13, 2019 Category: Biomedical Science Authors: Yunfeng Zhou, Wenda Xu and Hong Zhu Tags: Research article Source Type: research
Abnormal expression of TBX4 during anorectal development in rat embryos with ethylenethiourea-induced anorectal malformations
To assess the expression of T-box transcription factor 4 (TBX4) during the anorectal development in normal and ethylenethiourea (ETU)-induced anorectal malformations (ARM) rat embryos. (Source: Biological Research)
Source: Biological Research - May 4, 2019 Category: Biomedical Science Authors: Meng Li, Hailan Zhang, Huiying Liu, Hongzhong Tian, Xiaobing Tang, Yuzuo Bai and Weilin Wang Tags: Research article Source Type: research
ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway
Acute myeloid leukemia (AML) is an aggressive and mostly incurable hematological malignancy with frequent relapses after an initial response to standard chemotherapy. Therefore, novel therapies are urgently re... (Source: Biological Research)
Source: Biological Research - May 3, 2019 Category: Biomedical Science Authors: Yubin Feng, Xiaoxiao Hua, Ruowen Niu, Yan Du, Congjian Shi, Renpeng Zhou and Fei-Hu Chen Tags: Research article Source Type: research
Origination and selection of ABCDE and AGL6 subfamily MADS-box genes in gymnosperms and angiosperms
The morphological diversity of flower organs is closely related to functional divergence within the MADS-box gene family. Bryophytes and seedless vascular plants have MADS-box genes but do not have ABCDE or AGAMO... (Source: Biological Research)
Source: Biological Research - April 24, 2019 Category: Biomedical Science Authors: Gangxu Shen, Chih-Hui Yang, Chi-Yen Shen and Keng-Shiang Huang Tags: Research article Source Type: research
PELI3 mediates pro-tumor actions of down-regulated miR-365a-5p in non-small cell lung cancer
To analyze the relative expression of PELI3 and its mechanistic involvement in the non-small cell lung cancer (NSCLC). (Source: Biological Research)
Source: Biological Research - April 17, 2019 Category: Biomedical Science Authors: Yuzheng He, Yantao Shi, Ruilin Liu, Zhichao Wang, Baohua Wang, Shujun Li and Helin Zhang Tags: Research article Source Type: research
Involvement of endothelial CK2 in the radiation induced perivascular resistant niche (PVRN) and the induction of radioresistance for non-small cell lung cancer (NSCLC) cells
Tumor microenvironment (TME) plays a vital role in determining the outcomes of radiotherapy. As an important component of TME, vascular endothelial cells are involved in the perivascular resistance niche (PVRN... (Source: Biological Research)
Source: Biological Research - April 16, 2019 Category: Biomedical Science Authors: Qianwen Li, Yan Zong, Ke Li, Xiaohua Jie, Jiaxin Hong, Xiaoshu Zhou, Bian Wu, Zhenyu Li, Sheng Zhang, Gang Wu and Rui Meng Tags: Research article Source Type: research
Effect of cytoglobin overexpression on extracellular matrix component synthesis in human tenon fibroblasts
Conjunctival filtering bleb scar formation is the main reason for the failure of glaucoma filtration surgery. Cytoglobin (Cygb) has been reported to play an important role in extracellular matrix (ECM) remodel... (Source: Biological Research)
Source: Biological Research - April 16, 2019 Category: Biomedical Science Authors: Haiying Wei, Lili Lin, Xiaomei Zhang, Zhuolei Feng, Yeqing Wang, Yan You, Xiaodan Wang and Yongsheng Hou Tags: Research article Source Type: research
Molecular cloning and subcellular localization of six HDACs and their roles in response to salt and drought stress in kenaf (Hibiscus cannabinus L.)
Histone acetylation is an important epigenetic modification that regulates gene activity in response to stress. Histone acetylation levels are reversibly regulated by histone acetyltransferases (HATs) and histone... (Source: Biological Research)
Source: Biological Research - April 6, 2019 Category: Biomedical Science Authors: Fan Wei, Danfeng Tang, Zengqiang Li, Muhammad Haneef Kashif, Aziz Khan, Hai Lu, Ruixing Jia and Peng Chen Tags: Research article Source Type: research
