Palmitic acid-induced lipotoxicity promotes a novel interplay between Akt-mTOR, IRS-1, and FFAR1 signaling in pancreatic β-cells

Free fatty acid receptor 1 (FFAR1) is G-protein coupled receptor predominantly expressed in pancreatic β-cells that is activated by a variety of free fatty acids (FFAs). Once activated, it promotes glucose-sti...

Source: Biological Research - August 19, 2019 Category: Biomedical Science Authors: Sulaiman K. Marafie, Eman M. Al-Shawaf, Jehad Abubaker and Hossein Arefanian Tags: Research article Source Type: research