CXCL9 may serve as a potential biomarker for primary Sj ögren’s syndrome with extra-glandular manifestations
Primary Sj ögren's syndrome (pSS) is an autoimmune condition that causes harm to exocrine glands and also has extra-glandular manifestations (EGM). pSS patients with EGM have a worse prognosis than those with o... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 17, 2024 Category: Rheumatology Authors: Jingwei Hong, Hui Cheng, Ping Wang, Yanzhi Wu, Saisai Lu, Yan Zhou, Xiao bing Wang and Xiaofang Zhu Tags: Research Source Type: research
Safety and tolerability of intravenous immunoglobulin in patients with active dermatomyositis: results from the randomised, placebo-controlled ProDERM study
Dermatomyositis is an idiopathic inflammatory myopathy characterised by rashes and progressive muscle weakness. The recent ProDERM (Progress in DERMatomyositis) study is the first large randomised, placebo-con... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 17, 2024 Category: Rheumatology Authors: Rohit Aggarwal, Joachim Schessl, Christina Charles-Schoeman, Zsuzsanna Bata-Cs örgő, Mazen M. Dimachkie, Zoltan Griger, Sergey Moiseev, Chester V. Oddis, Elena Schiopu, Jiri Vencovský, Irene Beckmann, Elisabeth Clodi and Todd Levine Tags: Research Source Type: research
Children systemic lupus erythematosus-associated pancreatitis
To early recognise and improve the prognosis of children systemic lupus erythematosus (cSLE)-associated pancreatitis by summarising and analysing clinical features and prognosis data from 12 cases. (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 17, 2024 Category: Rheumatology Authors: Dan Zhang, Jianming Lai, Gaixiu Su, Jia Zhu, Min, Kang, Ming Li, Yingjie Xu and Li Meng Tags: Research Source Type: research
Protein profiling in systemic sclerosis patients with different pulmonary complications using proteomic antibody microarray
In this study, we aimed to identify biomarkers for detecting SSc pulmonar... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 17, 2024 Category: Rheumatology Authors: Jing Huang, Honglin Zhu, Sijia Liu, Mengtao Li, Yisha Li, Hui Luo and Xiaoxia Zuo Tags: Research Source Type: research
The causal relationship between immune cells and ankylosing spondylitis: a bidirectional Mendelian randomization study
Ankylosing spondylitis (AS) is one of several disorders known as seronegative spinal arthritis (SpA), the origin of which is unknown. Existing epidemiological data show that inflammatory and immunological fact... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 16, 2024 Category: Rheumatology Authors: Yuchang Fei, Huan Yu, Yulun Wu and Shanshan Gong Tags: Research Source Type: research
Molecular imaging for evaluation of synovitis associated with osteoarthritis: a narrative review
Recent evidence highlights the role of low-grade synovial inflammation in the progression of osteoarthritis (OA). Inflamed synovium of OA joints detected by imaging modalities are associated with subsequent pr... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 16, 2024 Category: Rheumatology Authors: Kwanghoon Lee, Soheil Niku, Sonya J. Koo, Ernest Belezzuoli and Monica Guma Tags: Review Source Type: research
Cartilage destruction in early rheumatoid arthritis patients correlates with CD21 −/low double-negative B cells
Involvement of B cells in the pathogenesis of rheumatoid arthritis (RA) is supported by the presence of disease-specific autoantibodies and the efficacy of treatment directed against B cells. B cells that expr... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 15, 2024 Category: Rheumatology Authors: Katrin Thorarinsdottir, Sarah McGrath, Kristina Forslind, Monica Leu Agelii, Anna-Karin Hultg ård Ekwall, Lennart T. H. Jacobsson, Anna Rudin, Inga-Lill Mårtensson and Inger Gjertsson Tags: Research Source Type: research
ADAM8 silencing suppresses the migration and invasion of fibroblast-like synoviocytes via FSCN1/MAPK cascade in osteoarthritis
Osteoarthritis (OA) is a degenerative joint disease that affects elderly populations worldwide, causing pain and disability. Alteration of the fibroblast-like synoviocytes (FLSs) phenotype leads to an imbalanc... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 13, 2024 Category: Rheumatology Authors: Kai Chen, Huaqiang Tao, Pengfei Zhu, Miao Chu, Xueyan Li, Yi Shi, Liyuan Zhang, Yaozeng Xu, Shujun Lv, Lixin Huang, Wei Huang and Dechun Geng Tags: Research Source Type: research
Impaired immune tolerance mediated by reduced Tfr cells in rheumatoid arthritis linked to gut microbiota dysbiosis and altered metabolites
Patients with rheumatoid arthritis (RA) showed impaired immune tolerance characterized by reduced follicular regulatory T (Tfr) cells, and they also exhibited altered gut microbiotas and their metabolites in R... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 13, 2024 Category: Rheumatology Authors: Ruihe Wu, Dongming Wang, Liyun Cheng, Rui Su, Baochen Li, Chunxue Fan, Chong Gao and Caihong Wang Tags: Research Source Type: research
Correction: NOD2 attenuates osteoarthritis via reprogramming the activation of synovial macrophages
(Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 13, 2024 Category: Rheumatology Authors: Changchuan Li, Zhuji Ouyang, Yuhsi Huang, Sipeng Lin, Shixun Li, Jing Xu, Taihe Liu, Jionglin Wu, Peidong Guo, Zhong Chen, Haoyu Wu and Yue Ding Tags: Correction Source Type: research
Specific-cytokine associations with outcomes in knee osteoarthritis subgroups: breaking down disease heterogeneity with phenotyping
In this study, we aimed to further characterize four knee... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 11, 2024 Category: Rheumatology Authors: Joan Calvet, Antoni Berenguer-Llergo, Crist óbal Orellana, María García-Manrique, Menna Rusiñol, Silvia Garcia-Cirera, Maria Llop, Marta Arévalo, Alba Garcia-Pinilla, Carlos Galisteo, Cristina Aymerich, Rafael Gómez, Alejandra Serrano, Anna Carreras Tags: Research Source Type: research
Synovial tissue features associated with poor prognosis in inflammatory arthritis
Inflammatory arthritis encompasses a group of immune-mediated diseases characterized by chronic joint inflammation. Despite having pathogenic mechanisms in common, the prognosis of rheumatoid arthritis (RA), p... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 10, 2024 Category: Rheumatology Authors: Ana Bel én Azuaga, Andrea Cuervo, Raquel Celis, Beatriz Frade-Sosa, Juan C. Sarmiento-Monroy, Virginia Ruiz-Esquide, José A. Gómez-Puerta, Raimon Sanmartí and Julio Ramírez Tags: Research Source Type: research
Characteristics of the synovial microenvironment and synovial mesenchymal stem cells with hip osteoarthritis of different bone morphologies
Variations in bone morphology in patients with hip osteoarthritis (HOA) can be broadly categorized into three types: atrophic, normotrophic, and hypertrophic. Despite the investigations examining clinical elem... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 10, 2024 Category: Rheumatology Authors: Yang Yang, Hideyuki Koga, Yusuke Nakagawa, Tomomasa Nakamura, Hiroki Katagiri, Ryohei Takada, Mai Katakura, Kunikazu Tsuji, Ichiro Sekiya and Kazumasa Miyatake Tags: Research Source Type: research
Management and treatment outcomes of rheumatoid arthritis in the era of biologic and targeted synthetic therapies: evaluation of 10-year data from the KURAMA cohort
Advances in rheumatoid arthritis (RA) treatment, highlighted by biological disease-modifying antirheumatic drugs (bDMARDs) and targeted synthetic DMARDs (tsDMARDs), have altered the paradigm of RA treatment in... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 9, 2024 Category: Rheumatology Authors: Takayuki Fujii, Koichi Murata, Hideo Onizawa, Akira Onishi, Masao Tanaka, Kosaku Murakami, Kohei Nishitani, Moritoshi Furu, Ryu Watanabe, Motomu Hashimoto, Hiromu Ito, Takao Fujii, Tsuneyo Mimori, Akio Morinobu and Shuichi Matsuda Tags: Research Source Type: research
Usefulness of 18F-FDG PET-CT for assessing large-vessel involvement in patients with suspected giant cell arteritis and negative temporal artery biopsy
To investigate the usefulness of 18F-FDG PET-CT for assessing large-vessel (LV) involvement in patients with suspected giant cell arteritis (GCA) and a negative temporal artery biopsy (TAB). (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - January 4, 2024 Category: Rheumatology Authors: Javier Narv áez, Paula Estrada, Paola Vidal-Montal, Iván Sánchez-Rodríguez, Aida Sabaté-Llobera, Joan Miquel Nolla and Montserrat Cortés-Romera Tags: Research Source Type: research
