Effects of low-intensity exercise on spontaneously developed knee osteoarthritis in male senescence-accelerated mouse prone 8
Osteoarthritis (OA) is a degenerative joint disease associated with aging, which often leads to joint stiffness and disability. Exercise is one of the most important non-pharmacological treatments and is presc... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - September 14, 2023 Category: Rheumatology Authors: Kosuke Norimatsu, Kazuki Nakanishi, Toshiro Ijuin, Shotaro Otsuka, Seiya Takada, Akira Tani, Ryoma Matsuzaki, Teruki Matsuoka and Harutoshi Sakakima Tags: Research Source Type: research
Arsenic trioxide demonstrates efficacy in a mouse model of preclinical systemic sclerosis
In this study, we assesse... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - September 12, 2023 Category: Rheumatology Authors: Anne Cauvet, Arthur Decellas, Christophe Guignabert, Dominique Rongvaux-Ga ïda, Raphaël Thuillet, Mina Ottaviani, Ly Tu, François Rieger, Jérôme Avouac and Yannick Allanore Tags: Research Source Type: research
Treatment patterns and clinical outcomes in patients with rheumatoid arthritis initiating etanercept, adalimumab, or Janus kinase inhibitor as first-line therapy: results from the real-world CorEvitas RA Registry
Real-world studies assessing the comparative effectiveness of biologic or targeted synthetic disease-modifying antirheumatic drugs (b/tsDMARDs) as first-line targeted therapy are scarce. We analyzed the real-w... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - September 9, 2023 Category: Rheumatology Authors: Dimitrios A. Pappas, Jacqueline O ’Brien, Lin Guo, Ying Shan, Joshua F. Baker, Gregory Kricorian, Scott Stryker and David H. Collier Tags: Research Source Type: research
Novel CSF biomarkers for diagnosis and integrated analysis of neuropsychiatric systemic lupus erythematosus: based on antibody profiling
Neuropsychiatric systemic lupus erythematosus (NPSLE), with various morbidities and multiple manifestations in the central nervous system, remains a limited standard for diagnosis. Our study was to discover no... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - September 8, 2023 Category: Rheumatology Authors: Jiali Ni, Chen Chen, Shuangan Wang, Xuan Liu, Liping Tan, Li Lu, Yu Fan, Yayi Hou, Huan Dou and Jun Liang Tags: Research Source Type: research
Efficacy and safety of tart cherry supplementary citrate mixture on gout patients: a prospective, randomized, controlled study
Low urine pH, which may be mediated by metabolic syndrome (MetS), is common in gout. Tart cherries are shown to improve MetS symptoms and possess anti-inflammatory properties. However, the efficacy of tart che... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - September 7, 2023 Category: Rheumatology Authors: Can Wang, Wenyan Sun, Nicola Dalbeth, Zhongjun Wang, Xuefeng Wang, Xiaopeng Ji, Xiaomei Xue, Lin Han, Lingling Cui, Xinde Li, Zhen Liu, Aichang Ji, Yuwei He, Mingshu Sun and Changgui Li Tags: Research Source Type: research
Differential sensitivity of the 2020 revised comprehensive diagnostic criteria and the 2019 ACR/EULAR classification criteria across IgG4-related disease phenotypes: results from a Norwegian cohort
We investigated sensitivity of the 2020 Revised Comprehensive Diagnostic Criteria (RCD) and the 2019 ACR/EULAR classification criteria across the four identified IgG4-related disease (IgG4-RD) phenotypes: “Pan... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - September 5, 2023 Category: Rheumatology Authors: Jens Vikse, Øyvind Midtvedt, Bjørg-Tilde Svanes Fevang, Torhild Garen, Øyvind Palm, Marianne Wallenius, Gunnstein Bakland, Katrine Brække Norheim, Øyvind Molberg and Anna-Maria Hoffmann-Vold Tags: Research Source Type: research
Correction: Deconvolution of whole blood transcriptomics identifies changes in immune cell composition in patients with systemic lupus erythematosus (SLE) treated with mycophenolate mofetil
(Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - September 4, 2023 Category: Rheumatology Authors: Mumina Akthar, Nisha Nair, Lucy M. Carter, Edward M. Vital, Emily Sutton, Neil McHugh, Ian N. Bruce and John A. Reynolds Tags: Correction Source Type: research
A bioavailable form of curcumin suppresses cationic host defence peptides cathelicidin and calprotectin in a murine model of collagen-induced arthritis
Curcumin, a component of the South-Asian spice turmeric, elicits anti-inflammatory functions. We have previously demonstrated that a highly bioavailable formulation of cucurmin, Cureit/Acumin ™ (CUR), can suppr... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - September 4, 2023 Category: Rheumatology Authors: Mahadevappa Hemshekhar, Dylan Lloyd, Hani El-Gabalawy and Neeloffer Mookherjee Tags: Correspondence Source Type: research
Anti-Ro52 positivity is associated with progressive interstitial lung disease in systemic sclerosis —an exploratory study
Interstitial lung disease (ILD) is the most common cause of death in patients with systemic sclerosis (SSc). Prognostic biomarkers are needed to identify SSc-ILD patients at risk for progressive pulmonary fibr... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - September 4, 2023 Category: Rheumatology Authors: Viggo Hamberg, Azita Sohrabian, Elizabeth R. Volkmann, Marie Wildt, Anna L öfdahl, Dirk M. Wuttge, Roger Hesselstrand, Göran Dellgren, Gunilla Westergren-Thorsson, Johan Rönnelid and Kristofer Andréasson Tags: Research Source Type: research
Clinical prediction models of rheumatoid arthritis and its complications: focus on cardiovascular disease and interstitial lung disease
Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune disease of unknown etiology with erosive, symmetric polyarthritis as the main clinical manifestations. Its basic pathological changes are the format... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - September 1, 2023 Category: Rheumatology Authors: Yubo Shao, Hong Zhang, Qi Shi, Yongjun Wang and Qianqian Liang Tags: Review Source Type: research
CD64 as novel molecular imaging marker for the characterization of synovitis in rheumatoid arthritis
Rheumatoid arthritis (RA) is one of the most prevalent and debilitating joint diseases worldwide. RA is characterized by synovial inflammation (synovitis), which is linked to the development of joint destructi... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - August 31, 2023 Category: Rheumatology Authors: Wessel F. Theeuwes, Irene Di Ceglie, Daphne N. Dorst, Arjen B. Blom, Desiree L. Bos, Thomas Vogl, Sander W. Tas, Pilar Jimenez-Royo, Mats Bergstrom, Matthew Cleveland, Peter M. van der Kraan, Peter Laverman, Marije I. Koenders, Peter L. van Lent and Marti Tags: Research Source Type: research
A cysteine proteinase inhibitor ALLN alleviates bleomycin-induced skin and lung fibrosis
Systemic sclerosis (SSc) is a connective tissue disease that is characterized by fibrosis in the skin and internal organs, such as the lungs. Activated differentiation of progenitor cells, which are mainly res... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - August 25, 2023 Category: Rheumatology Authors: Hiroshi Kasamatsu, Takenao Chino, Takumi Hasegawa, Natsuko Utsunomiya, Akira Utsunomiya, Masami Yamada, Noritaka Oyama and Minoru Hasegawa Tags: Research Source Type: research
Extracellular matrix turnover biomarkers reflect pharmacodynamic effects and treatment response of adalimumab in patients with axial spondyloarthritis —results from two randomized controlled trials
To investigate if extracellular matrix (ECM) blood-based biomarkers reflect the pharmacodynamic effect and response to TNF- α inhibitor therapy (adalimumab, ADA), in patients with axial spondyloarthritis (axSpA). (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - August 25, 2023 Category: Rheumatology Authors: Helena Port, Signe Holm Nielsen, Peder Frederiksen, Sofie Falkenl øve Madsen, Anne-Christine Bay-Jensen, Inge Juul Sørensen, Bente Jensen, Anne Gitte Loft, Ole Rintek Madsen, Mikkel Østergaard and Susanne Juhl Pedersen Tags: Research Source Type: research
Cellular characterisation of advanced osteoarthritis knee synovium
Osteoarthritis (OA) is increasingly recognised as a whole joint disease, with an important role for synovium. However, the repertoire of immune cells and fibroblasts that constitute OA synovium remains underst... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - August 23, 2023 Category: Rheumatology Authors: Jolet Y. Mimpen, Robert Hedley, Anna Ridley, Mathew J. Baldwin, Dylan Windell, Ananya Bhalla, Lorenzo Ramos-Mucci, Christopher D. Buckley, Mark C. Coles, Abtin Alvand, Andrew J. Price, Andrew J. Carr, Stephanie G. Dakin and Sarah J. B. Snelling Tags: Research Source Type: research
Clinical characteristics and prognosis in systemic lupus erythematosus-associated pulmonary arterial hypertension based on consensus clustering and risk prediction model
This study aims to explore the clinical characteristics and prognosis in SLE-PAH based on consensus cluster... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - August 23, 2023 Category: Rheumatology Authors: Mengmeng Dai, Chunyi Zhang, Chaoying Li, Qianqian Wang, Congcong Gao, Runzhi Yue, Menghui Yao, Zhaohui Su and Zhaohui Zheng Tags: Research Source Type: research
