Left ventricular remodeling in rheumatoid arthritis patients without clinical heart failure
Rheumatoid arthritis (RA) patients have a 1.5- to twofold higher risk of developing heart failure (HF) and a twofold increased risk of HF-associated mortality compared to those without RA. HF is preceded subcl... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - July 21, 2023 Category: Rheumatology Authors: Elizabeth Park, Kazato Ito, Christopher Depender, Jon T. Giles and Joan Bathon Tags: Correspondence Source Type: research
Chronic neck pain is associated with increased mortality in individuals with osteoarthritis: results from the NHANES database prospective cohort study
Neck pain (NP) is a common symptom reported in the elderly. However, no study has examined the relationship between NP and osteoarthritis (OA) so far, and this study aimed to investigate the association of nec... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - July 19, 2023 Category: Rheumatology Authors: Xi Chen, Lihua Gong, Cheng Li, Siyuan Wang and Yixin Zhou Tags: Research Source Type: research
Sirt3 improves monosodium urate crystal-induced inflammation by suppressing Acod1 expression
Previous studies have revealed that Sirt3 deficiency is associated with several inflammatory responses. The purpose of this study is to investigate the role and potential molecular mechanisms of Sirt3 in the i... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - July 19, 2023 Category: Rheumatology Authors: Linxi Lv, Hui Jiang, Dianze Song, Xiaoqin Zhou, Feng Chen, Long Ren, Yongen Xie and Mei Zeng Tags: Research Source Type: research
A Mendelian randomization study of serum uric acid with the risk of venous thromboembolism
Observational studies have linked hyperuricemia with venous thromboembolism (VTE). We aimed to investigate whether there are causal relationships between uric acid levels and VTE and its subtypes, including de... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - July 19, 2023 Category: Rheumatology Authors: Lixian Ji and Peng Shu Tags: Research Source Type: research
Learnings from clinical trials in patients with connective tissue disease-associated interstitial lung disease
Many clinical trial results are available to inform best practices in the treatment of patients with connective tissue disease-associated interstitial lung disease (CTD-ILD). (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - July 8, 2023 Category: Rheumatology Authors: Jean Paul Higuero Sevilla, Areeka Memon and Monique Hinchcliff Tags: Review Source Type: research
The access route through the anatomical snuffbox in ultrasound-guided synovial biopsy of the wrist allows for a safe and effective collection of tissue samples in inflammatory arthritis
A proof-of-concept study to evaluate the feasibility and safety of minimally invasive ultrasound (US)-guided synovial biopsy of the radiocarpal (RC) joint using the anatomical snuffbox as an access route. (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - July 8, 2023 Category: Rheumatology Authors: Ludovico De Stefano, Serena Bugatti, Veronica Piccin, Gioacchino D ’Ambrosio, Terenzj Luvaro, Blerina Xoxi, Carlomaurizio Montecucco and Antonio Manzo Tags: Research Source Type: research
Giant cell arteritis-related cerebrovascular ischemic events: a French retrospective study of 271 patients, systematic review of the literature and meta-analysis
Cerebrovascular ischemic events (CIE) are among the most severe complications of giant cell arteritis (GCA). Heterogeneity between different studies in the definition of GCA-related CIE leads to uncertainty re... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - July 7, 2023 Category: Rheumatology Authors: Thomas Penet, Marc Lambert, Clio Baillet, Olivier Outteryck, Hilde H énon, Sandrine Morell-Dubois, Eric Hachulla, David Launay and Mohammad Ryadh Pokeerbux Tags: Research Source Type: research
Aberrant mechanical loading induces annulus fibrosus cells apoptosis in intervertebral disc degeneration via mechanosensitive ion channel Piezo1
Intervertebral disc degeneration (IVDD) is closely associated with the structural damage in the annulus fibrosus (AF). Aberrant mechanical loading is an important inducement of annulus fibrosus cells (AFCs) ap... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - July 7, 2023 Category: Rheumatology Authors: Chenhao Liu, Xiaoxin Gao, Jinhui Lou, Haiyin Li, Yuxuan Chen, Molong Chen, Yuyao Zhang, Zhilei Hu, Xian Chang, Menglin Luo, Yu Zhai and Changqing Li Tags: Research Source Type: research
Comorbidity in incident osteoarthritis cases and matched controls using electronic health record data
This study aimed to determine the association of a wide range of previously diagnosed comorbidities in adults with newly diagnosed OA compared wit... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - July 4, 2023 Category: Rheumatology Authors: Anne Kamps, Jos Runhaar, Maria A. J. de Ridder, Marcel de Wilde, Johan van der Lei, Weiya Zhang, Daniel Prieto-Alhambra, Martin Englund, Evelien I. T. de Schepper and Sita M. A. Bierma-Zeinstra Tags: Research Source Type: research
Correction: More than skin ‑deep: visceral fat is strongly associated with disease activity, function and metabolic indices in psoriatic disease
(Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - July 4, 2023 Category: Rheumatology Authors: Tim Blake, Nicola J. Gullick, Charles E. Hutchinson, Abhir Bhalerao, Sarah Wayte, Andrew Weedall and Thomas M. Barber Tags: Correction Source Type: research
CC chemokines and receptors in osteoarthritis: new insights and potential targets
Osteoarthritis (OA) is a prevalent degenerative disease accompanied by the activation of innate and adaptive immune systems-associated inflammatory responses. Due to the local inflammation, the expression of v... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - July 3, 2023 Category: Rheumatology Authors: Yuchen Zhang, Di Liu, Djandan Tadum Arthur Vithran, Bosomtwe Richmond Kwabena, Wenfeng Xiao and Yusheng Li Tags: Review Source Type: research
Renal interferon-inducible protein 16 expression is associated with disease activity and prognosis in lupus nephritis
Lupus nephritis (LN) is one of the most severe complications of systemic lupus erythematosus (SLE). However, the current management of LN remains unsatisfactory due to sneaky symptoms during early stages and l... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - July 1, 2023 Category: Rheumatology Authors: Xueyao Wang, Shaojie Fu, Jinyu Yu, Fuzhe Ma, Lihong Zhang, Jiahui Wang, Luyu Wang, Yue Tan, Huanfa Yi, Hao Wu and Zhonggao Xu Tags: Research Source Type: research
Deconvolution of whole blood transcriptomics identifies changes in immune cell composition in patients with systemic lupus erythematosus (SLE) treated with mycophenolate mofetil
Systemic lupus erythematosus (SLE) is a clinically and biologically heterogeneous autoimmune disease. We explored whether the deconvolution of whole blood transcriptomic data could identify differences in pred... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - June 30, 2023 Category: Rheumatology Authors: Mumina Akhtar, Nisha Nair, Lucy M. Carter, Edward M. Vital, Emily Sutton, Neil McHugh, Ian N. Bruce and John A. Reynolds Tags: Research Source Type: research
Mepolizumab exerts crucial effects on glucocorticoid discontinuation in patients with eosinophilic granulomatosis with polyangiitis: a retrospective study of 27 cases at a single center in Japan
To investigate the efficacy of mepolizumab in patients with eosinophilic granulomatosis with polyangiitis (EGPA) and factors contributing to glucocorticoid (GC) discontinuation. (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - June 26, 2023 Category: Rheumatology Authors: Takashi Yamane and Akira Hashiramoto Tags: Research Source Type: research
More than skin-deep: visceral fat is strongly associated with disease activity, function and metabolic indices in psoriatic disease
To compare body composition between patients with psoriatic disease (PsD), including cutaneous psoriasis (PsO) and psoriatic arthritis (PsA), and controls, and to explore associations between disease activity ... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - June 23, 2023 Category: Rheumatology Authors: T. Blake, N. Gullick, C. E. Hutchinson, A. Bhalerao, S. Wayte, A. Weedall and T. M. Barber Tags: Research Source Type: research
