Clinical characteristics and survival of pulmonary arterial hypertension with or without interstitial lung disease in systemic sclerosis
To describe the clinical phenotype and prognosis of people in the Australian Scleroderma (SSc) Cohort Study with pulmonary arterial hypertension (PAH) with or without interstitial lung disease (ILD). (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - May 12, 2023 Category: Rheumatology Authors: Jessica L. Fairley, Dylan Hansen, Laura Ross, Susanna Proudman, Joanne Sahhar, Gene-Siew Ngian, Jennifer Walker, Lauren V. Host, Kathleen Morrisroe, Diane Apostolopoulous, Nava Ferdowsi, Michelle Wilson, Maryam Tabesh, Wendy Stevens and Mandana Nikpour Tags: Research Source Type: research
Risk factors for avascular necrosis in patients with systemic lupus erythematosus: a multi-center cohort study of Chinese SLE Treatment and Research Group (CSTAR) Registry XXII
Avascular necrosis is a common organ damage in SLE patients, which can influence patients ’ life quality. Conflicting results exist in risk factors of AVN in SLE patients. The aim of this study was to illustrat... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - May 12, 2023 Category: Rheumatology Authors: Cheng Cheng, Can Huang, Zhen Chen, Feng Zhan, Xinwang Duan, Yongfu Wang, Cheng Zhao, Zhenbiao Wu, Jian Xu, Hongbin Li, Min Yang, Rui Wu, Jiuliang Zhao, Shangzhu Zhang, Qian Wang, Xiaomei Leng & hellip; Tags: Research Source Type: research
Expression of S100A8 protein on B cells is associated with disease activity in patients with systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an intractable disease characterized by autoantibody production and autoreactive B and T cell proliferation. Although several studies have revealed multiple genetic and en... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - May 10, 2023 Category: Rheumatology Authors: Koji Kitagori, Takuma Oku, Masaki Wakabayashi, Tomoya Nakajima, Ran Nakashima, Kosaku Murakami, Yoshitaka Hirayama, Yasushi Ishihama, Koichiro Ohmura, Akio Morinobu, Tsuneyo Mimori and Hajime Yoshifuji Tags: Research Source Type: research
Association between air pollutants and initiation of biological therapy in patients with ankylosing spondylitis: a nationwide, population-based, nested case –control study
Outdoor air pollution has been found to trigger systemic inflammatory responses and aggravate the activity of certain rheumatic diseases. However, few studies have explored the influence of air pollution on th... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - May 5, 2023 Category: Rheumatology Authors: Chung-Mao Kao, Yi-Ming Chen, Wen-Nan Huang, Yi-Hsing Chen and Hsin-Hua Chen Tags: Research Source Type: research
Multi-omics profiling reveals potential alterations in rheumatoid arthritis with different disease activity levels
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune inflammatory disease, the pathogenesis of which is not clear. Clinical remission, or decreased disease activity, is the aim of treatment for RA. Howe... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - May 3, 2023 Category: Rheumatology Authors: Jianghua Chen, Shilin Li, Jing Zhu, Wei Su, Congcong Jian, Jie Zhang, Jianhong Wu, Tingting Wang, Weihua Zhang, Fanwei Zeng, Shengjia Chang, Lihua Jia, Jiang Su, Yi Zhao, Jing Wang and Fanxin Zeng Tags: Research Source Type: research
Cutaneous lesions in psoriatic arthritis are enriched in chemokine transcriptomic pathways
Skin from people with psoriasis has been extensively studied and is assumed to be identical to skin from those with psoriatic arthritis (PsA). Chemokines and the CC chemokine scavenger receptor ACKR2 are upreg... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - May 2, 2023 Category: Rheumatology Authors: Hanna Johnsson, John Cole, Stefan Siebert, Iain B. McInnes and Gerard Graham Tags: Research Source Type: research
Correction: The influence of intrathecal injection of methotrexate and dexamethasone on neuropsychiatric systemic lupus erythematosus (NPSLE): a retrospective cohort study of 386 patients with NPSLE
(Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 29, 2023 Category: Rheumatology Authors: Yuxue Nie, Boyuan Sun, Xin He, Minmin Zheng, Di Wu, Yunjiao Yang, Li Zhang, Wei Bai, Nan Jiang, Lin Qiao, Can Huang, Shuang Zhou, Jiaxin Zhou, Linyi Peng, Jingwen Niu, Mengtao Li & hellip; Tags: Correction Source Type: research
Stiffness and axial pain are associated with the progression of calcification in a mouse model of diffuse idiopathic skeletal hyperostosis
This study exami... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 29, 2023 Category: Rheumatology Authors: Dale E. Fournier, Matthew A. Veras, Courtney R. Brooks, Diana Quinonez, Magali Millecamps, Laura S. Stone and Cheryle A. S éguin Tags: Research Source Type: research
Identification of key biomarkers associated with immune cells infiltration for myocardial injury in dermatomyositis by integrated bioinformatics analysis
Dermatomyositis (DM) is an acquired autoimmune disease that can cause damage to various organs, including the heart muscle. However, the mechanisms underlying myocardial injury in DM are not yet fully understood. (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 28, 2023 Category: Rheumatology Authors: Yue Zhang, Linwei Shan, Dongyu Li, Yinghong Tang, Wei Qian, Jiayi Dai, Mengdi Du, Xiaoxuan Sun, Yinsu Zhu, Qiang Wang and Lei Zhou Tags: Research Source Type: research
Sustained low functional impairment in axial spondyloarthritis (axSpA): which are the primary outcomes that should be targeted to achieve this?
To (i) determine whether sustained disease activity states, as measured by Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Ankylosing Spondylitis Disease Activity Score (ASDAS), impact function... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 28, 2023 Category: Rheumatology Authors: Walter P. Maksymowych, Robert D. Inman, Louis Bessette, Proton Rahman, Emmanouil Rampakakis, Odalis Asin-Milan, Meagan Rachich, Anne Marilise Marrache and Allen J. Lehman Tags: Research Source Type: research
Comparisons of treatment satisfaction and health-related quality of life in patients with rheumatoid arthritis treated with tofacitinib and adalimumab
As significant advances in the field of treatment for rheumatoid arthritis (RA), there is a great need to identify the healthcare outcomes such as treatment satisfaction and health-related quality of life (HRQ... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 27, 2023 Category: Rheumatology Authors: Seong-Kyu Kim, Sang-Heon Lee, Jiyu Sun, Soo Hyun Lee, Ja-Young Jeon, Hyun-Jeong Yoo and Jung-Yoon Choe Tags: Research Source Type: research
Glutathione peroxidase 3 is a novel clinical diagnostic biomarker and potential therapeutic target for neutrophils in rheumatoid arthritis
Neutrophils have a critical role in the pathogenesis of rheumatoid arthritis (RA) with immune system dysfunction. However, the molecular mechanisms of this process mediated by neutrophils still remain elusive.... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 22, 2023 Category: Rheumatology Authors: Tao Chen, Zhen Zhou, Minge Peng, Huifang Hu, Rui Sun, Jiayi Xu, Chenxi Zhu, Yanhong Li, Qiuping Zhang, Yubin Luo, Bin Yang, Lunzhi Dai, Yi Liu, Luis E. Mu ñoz, Liesu Meng, Martin Herrmann & hellip; Tags: Research Source Type: research
The trajectory of clinical responses in patients with early rheumatoid arthritis who achieve sustained remission in response to abatacept: subanalysis of AVERT-2, a randomized phase IIIb study
AVERT-2 (a phase IIIb, two-stage study) evaluated abatacept + methotrexate versus methotrexate alone, in methotrexate-naive, anti-citrullinated protein antibody-positive patients with early (≤ 6 months), activ... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 22, 2023 Category: Rheumatology Authors: Paul Emery, Yoshiya Tanaka, Vivian P. Bykerk, Clifton O. Bingham, Thomas W. J. Huizinga, Gustavo Citera, Kuan-Hsiang Gary Huang, Chun Wu, Sean E. Connolly, Yedid Elbez, Robert Wong, Karissa Lozenski and Roy Fleischmann Tags: Research Source Type: research
Quantitative prediction of radiographic progression in patients with axial spondyloarthritis using neural network model in a real-world setting
Predicting radiographic progression in axial spondyloarthritis (axSpA) remains limited because of the complex interaction between multiple associated factors and individual variability in real-world settings. ... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 20, 2023 Category: Rheumatology Authors: In-Woon Baek, Seung Min Jung, Yune-Jung Park, Kyung-Su Park and Ki-Jo Kim Tags: Research Source Type: research
Transforming growth factor beta 1 is associated with subclinical carotid atherosclerosis in patients with systemic lupus erythematosus
Transforming growth factor beta (TGF- β1) is a multifunctional cytokine that has anti-inflammatory and immunosuppressive effects. TGF-β1 has been linked to cardiovascular disease in the general population. The ... (Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 17, 2023 Category: Rheumatology Authors: Fuensanta G ómez-Bernal, Juan Carlos Quevedo-Abeledo, María García-González, Yolanda Fernández-Cladera, Agustín F. González-Rivero, Candelaria Martín-González, Miguel Á. González-Gay and Iván Ferraz-Amaro Tags: Research Source Type: research
