The risk factors and clinical outcomes in hepatitis B seropositive and seronegative renal transplant patients
Conclusion: Individuals, independent of HBsAg status, had similar prognosis in terms of patient and graft survival, acute rejection rate, and cancer development. The absence of either pre-transplant anti-HBV medication or lifelong antiviral therapy was significantly associated with an increased risk of HBV reactivation.PMID:38498992 | DOI:10.1159/000538231 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 18, 2024 Category: Urology & Nephrology Authors: Yu-Lien Tsai Meng-Hsuan Chung Niang-Cheng Lin Cheng-Yen Chen Yao-Ping Lin Ming-Tsun Tsai Hsin-Lin Tsai Yee-An Chen Shuo-Ming Ou Chi-Jen Chu Tsai-Hung Wu Chang-Youh Tsai Source Type: research
Acute and chronic kidney dysfunction and prognosis following thrombectomy for ischemic stroke
CONCLUSION: AKI is independently associated with poorer functional outcome and increased mortality at 3 months. CKD was not an independent risk factor for 3-month mortality or poor functional prognosis.PMID:38499002 | DOI:10.1159/000536493 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 18, 2024 Category: Urology & Nephrology Authors: Micka ël Bobot Jean-Fran çois Hak Barbara Casolla Jean-Daniel Dehondt St éphane Burtey Emilie Doche Laurent Suissa Source Type: research
The risk factors and clinical outcomes in hepatitis B seropositive and seronegative renal transplant patients
Conclusion: Individuals, independent of HBsAg status, had similar prognosis in terms of patient and graft survival, acute rejection rate, and cancer development. The absence of either pre-transplant anti-HBV medication or lifelong antiviral therapy was significantly associated with an increased risk of HBV reactivation.PMID:38498992 | DOI:10.1159/000538231 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 18, 2024 Category: Urology & Nephrology Authors: Yu-Lien Tsai Meng-Hsuan Chung Niang-Cheng Lin Cheng-Yen Chen Yao-Ping Lin Ming-Tsun Tsai Hsin-Lin Tsai Yee-An Chen Shuo-Ming Ou Chi-Jen Chu Tsai-Hung Wu Chang-Youh Tsai Source Type: research
Acute and chronic kidney dysfunction and prognosis following thrombectomy for ischemic stroke
CONCLUSION: AKI is independently associated with poorer functional outcome and increased mortality at 3 months. CKD was not an independent risk factor for 3-month mortality or poor functional prognosis.PMID:38499002 | DOI:10.1159/000536493 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 18, 2024 Category: Urology & Nephrology Authors: Micka ël Bobot Jean-Fran çois Hak Barbara Casolla Jean-Daniel Dehondt St éphane Burtey Emilie Doche Laurent Suissa Source Type: research
Onco-Hypertension in Patients with Kidney Disease
This article reviews available literature and proposes a step-by-step approach to manage cancer patients with concurrent hypertension and kidney disease.KEY MESSAGES: For antineoplastic medications with known hypertensive effect, blood pressure should be checked at baseline and serially during cancer treatment. Hypertensive crisis with end-organ damage, significant proteinuria, microscopic hematuria, or unexplained acute kidney injury necessitates drug cessation until further evaluation and resolution. In patients with chronic kidney disease and cancer therapy-related hypertension, angiotensin-converting enzyme inhibitor o...
Source: American Journal of Nephrology - March 17, 2024 Category: Urology & Nephrology Authors: Shubhi Pandey Simon Kashfi Susana Hong Amar Kalaria Agnes S Kim Source Type: research
Diagnostic yield of exome sequencing in early onset hypertensive nephropathy in adults
CONCLUSIONS: The high diagnostic yield of ES (15%) in a population of patients thought to have HN casts further doubts on the validity of the existing diagnosis criteria, including histological criteria, supposed to characterize the condition. This was especially true in patients with no African ancestry where ES positivity reached 30%.PMID:38471460 | DOI:10.1159/000538173 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 12, 2024 Category: Urology & Nephrology Authors: Justine Serre Alice Doreille Laure Raymond Gaspard Suc Micka ël Bobot Marine Dancer C édric Rafat Laurent Mesnard Source Type: research
Association of Proton Pump Inhibitor Use and Immune Checkpoint Inhibitor Mediated Acute Kidney Injury: A Meta-Analysis and a Review of Related Outcomes
CONCLUSION: This meta-analysis highlights the importance of cautious PPI prescription in cancer patients undergoing ICI therapy. Clinicians are advised to evaluate the risks and benefits of PPI use and consider alternative therapies when feasible.PMID:38471492 | DOI:10.1159/000538274 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 12, 2024 Category: Urology & Nephrology Authors: Arjunmohan Mohan Pajaree Krisanapan Supawit Tangpanithandee Charat Thongprayoon Swetha Rani Kanduri Wisit Cheungpasitporn Sandra M Herrmann Source Type: research
Diagnostic yield of exome sequencing in early onset hypertensive nephropathy in adults
CONCLUSIONS: The high diagnostic yield of ES (15%) in a population of patients thought to have HN casts further doubts on the validity of the existing diagnosis criteria, including histological criteria, supposed to characterize the condition. This was especially true in patients with no African ancestry where ES positivity reached 30%.PMID:38471460 | DOI:10.1159/000538173 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 12, 2024 Category: Urology & Nephrology Authors: Justine Serre Alice Doreille Laure Raymond Gaspard Suc Micka ël Bobot Marine Dancer C édric Rafat Laurent Mesnard Source Type: research
Association of Proton Pump Inhibitor Use and Immune Checkpoint Inhibitor Mediated Acute Kidney Injury: A Meta-Analysis and a Review of Related Outcomes
CONCLUSION: This meta-analysis highlights the importance of cautious PPI prescription in cancer patients undergoing ICI therapy. Clinicians are advised to evaluate the risks and benefits of PPI use and consider alternative therapies when feasible.PMID:38471492 | DOI:10.1159/000538274 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 12, 2024 Category: Urology & Nephrology Authors: Arjunmohan Mohan Pajaree Krisanapan Supawit Tangpanithandee Charat Thongprayoon Swetha Rani Kanduri Wisit Cheungpasitporn Sandra M Herrmann Source Type: research
Diagnostic yield of exome sequencing in early onset hypertensive nephropathy in adults
CONCLUSIONS: The high diagnostic yield of ES (15%) in a population of patients thought to have HN casts further doubts on the validity of the existing diagnosis criteria, including histological criteria, supposed to characterize the condition. This was especially true in patients with no African ancestry where ES positivity reached 30%.PMID:38471460 | DOI:10.1159/000538173 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 12, 2024 Category: Urology & Nephrology Authors: Justine Serre Alice Doreille Laure Raymond Gaspard Suc Micka ël Bobot Marine Dancer C édric Rafat Laurent Mesnard Source Type: research
Association of Proton Pump Inhibitor Use and Immune Checkpoint Inhibitor Mediated Acute Kidney Injury: A Meta-Analysis and a Review of Related Outcomes
CONCLUSION: This meta-analysis highlights the importance of cautious PPI prescription in cancer patients undergoing ICI therapy. Clinicians are advised to evaluate the risks and benefits of PPI use and consider alternative therapies when feasible.PMID:38471492 | DOI:10.1159/000538274 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 12, 2024 Category: Urology & Nephrology Authors: Arjunmohan Mohan Pajaree Krisanapan Supawit Tangpanithandee Charat Thongprayoon Swetha Rani Kanduri Wisit Cheungpasitporn Sandra M Herrmann Source Type: research
Diagnostic yield of exome sequencing in early onset hypertensive nephropathy in adults
CONCLUSIONS: The high diagnostic yield of ES (15%) in a population of patients thought to have HN casts further doubts on the validity of the existing diagnosis criteria, including histological criteria, supposed to characterize the condition. This was especially true in patients with no African ancestry where ES positivity reached 30%.PMID:38471460 | DOI:10.1159/000538173 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 12, 2024 Category: Urology & Nephrology Authors: Justine Serre Alice Doreille Laure Raymond Gaspard Suc Micka ël Bobot Marine Dancer C édric Rafat Laurent Mesnard Source Type: research
Association of Proton Pump Inhibitor Use and Immune Checkpoint Inhibitor Mediated Acute Kidney Injury: A Meta-Analysis and a Review of Related Outcomes
CONCLUSION: This meta-analysis highlights the importance of cautious PPI prescription in cancer patients undergoing ICI therapy. Clinicians are advised to evaluate the risks and benefits of PPI use and consider alternative therapies when feasible.PMID:38471492 | DOI:10.1159/000538274 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - March 12, 2024 Category: Urology & Nephrology Authors: Arjunmohan Mohan Pajaree Krisanapan Supawit Tangpanithandee Charat Thongprayoon Swetha Rani Kanduri Wisit Cheungpasitporn Sandra M Herrmann Source Type: research
Deliverables from Metabolomics in Kidney Disease: Adenine, New Insights and Implication for Clinical Decision Making
Am J Nephrol. 2024 Mar 3. doi: 10.1159/000538051. Online ahead of print.ABSTRACTBACKGROUND: Chronic kidney disease (CKD) presents a persistent global health challenge, characterized by complex pathophysiology and diverse progression patterns. Metabolomics has emerged as a valuable tool in unraveling the intricate molecular mechanisms driving CKD progression.SUMMARY: This comprehensive review provides a summary of recent progress in the field of metabolomics in kidney disease with a focus on spatial metabolomics to shed important insights to enhancing our understanding of CKD progression, emphasizing its transformative pote...
Source: American Journal of Nephrology - March 3, 2024 Category: Urology & Nephrology Authors: Nagarjunachary Ragi Kumar Sharma Source Type: research
Deliverables from Metabolomics in Kidney Disease: Adenine, New Insights and Implication for Clinical Decision Making
Am J Nephrol. 2024 Mar 3. doi: 10.1159/000538051. Online ahead of print.ABSTRACTBACKGROUND: Chronic kidney disease (CKD) presents a persistent global health challenge, characterized by complex pathophysiology and diverse progression patterns. Metabolomics has emerged as a valuable tool in unraveling the intricate molecular mechanisms driving CKD progression.SUMMARY: This comprehensive review provides a summary of recent progress in the field of metabolomics in kidney disease with a focus on spatial metabolomics to shed important insights to enhancing our understanding of CKD progression, emphasizing its transformative pote...
Source: American Journal of Nephrology - March 3, 2024 Category: Urology & Nephrology Authors: Nagarjunachary Ragi Kumar Sharma Source Type: research
