Biomarker Enrichment in Sepsis Associated Acute Kidney Injury: Finding High-Risk Patients in the ICU
Am J Nephrol. 2023 Oct 16. doi: 10.1159/000534608. Online ahead of print.ABSTRACT Abstract: Background: Sepsis associated Acute kidney injury (AKI) is a leading comorbidity in admissions to the intensive care unit. While a gold standard definition exists, it remains imperfect and does not allow for the timely identification of patients in the setting of critical illness. This review will discuss the use of biochemical and electronic biomarkers to allow for prognostic and predictive enrichment of patients with sepsis associated AKI over and above the use of serum creatinine and urine output. Summary: Current data suggest th...
Source: American Journal of Nephrology - October 16, 2023 Category: Urology & Nephrology Authors: Louis Baeseman Samantha Gunning Jay L Koyner Source Type: research
Biomarker Enrichment in Sepsis Associated Acute Kidney Injury: Finding High-Risk Patients in the ICU
Am J Nephrol. 2023 Oct 16. doi: 10.1159/000534608. Online ahead of print.ABSTRACT Abstract: Background: Sepsis associated Acute kidney injury (AKI) is a leading comorbidity in admissions to the intensive care unit. While a gold standard definition exists, it remains imperfect and does not allow for the timely identification of patients in the setting of critical illness. This review will discuss the use of biochemical and electronic biomarkers to allow for prognostic and predictive enrichment of patients with sepsis associated AKI over and above the use of serum creatinine and urine output. Summary: Current data suggest th...
Source: American Journal of Nephrology - October 16, 2023 Category: Urology & Nephrology Authors: Louis Baeseman Samantha Gunning Jay L Koyner Source Type: research
Biomarker Enrichment in Sepsis Associated Acute Kidney Injury: Finding High-Risk Patients in the ICU
Am J Nephrol. 2023 Oct 16. doi: 10.1159/000534608. Online ahead of print.ABSTRACT Abstract: Background: Sepsis associated Acute kidney injury (AKI) is a leading comorbidity in admissions to the intensive care unit. While a gold standard definition exists, it remains imperfect and does not allow for the timely identification of patients in the setting of critical illness. This review will discuss the use of biochemical and electronic biomarkers to allow for prognostic and predictive enrichment of patients with sepsis associated AKI over and above the use of serum creatinine and urine output. Summary: Current data suggest th...
Source: American Journal of Nephrology - October 16, 2023 Category: Urology & Nephrology Authors: Louis Baeseman Samantha Gunning Jay L Koyner Source Type: research
Biomarker Enrichment in Sepsis Associated Acute Kidney Injury: Finding High-Risk Patients in the ICU
Am J Nephrol. 2023 Oct 16. doi: 10.1159/000534608. Online ahead of print.ABSTRACT Abstract: Background: Sepsis associated Acute kidney injury (AKI) is a leading comorbidity in admissions to the intensive care unit. While a gold standard definition exists, it remains imperfect and does not allow for the timely identification of patients in the setting of critical illness. This review will discuss the use of biochemical and electronic biomarkers to allow for prognostic and predictive enrichment of patients with sepsis associated AKI over and above the use of serum creatinine and urine output. Summary: Current data suggest th...
Source: American Journal of Nephrology - October 16, 2023 Category: Urology & Nephrology Authors: Louis Baeseman Samantha Gunning Jay L Koyner Source Type: research
Biomarker Enrichment in Sepsis Associated Acute Kidney Injury: Finding High-Risk Patients in the ICU
Am J Nephrol. 2023 Oct 16. doi: 10.1159/000534608. Online ahead of print.ABSTRACT Abstract: Background: Sepsis associated Acute kidney injury (AKI) is a leading comorbidity in admissions to the intensive care unit. While a gold standard definition exists, it remains imperfect and does not allow for the timely identification of patients in the setting of critical illness. This review will discuss the use of biochemical and electronic biomarkers to allow for prognostic and predictive enrichment of patients with sepsis associated AKI over and above the use of serum creatinine and urine output. Summary: Current data suggest th...
Source: American Journal of Nephrology - October 16, 2023 Category: Urology & Nephrology Authors: Louis Baeseman Samantha Gunning Jay L Koyner Source Type: research
Biomarker Enrichment in Sepsis Associated Acute Kidney Injury: Finding High-Risk Patients in the ICU
Am J Nephrol. 2023 Oct 16. doi: 10.1159/000534608. Online ahead of print.ABSTRACT Abstract: Background: Sepsis associated Acute kidney injury (AKI) is a leading comorbidity in admissions to the intensive care unit. While a gold standard definition exists, it remains imperfect and does not allow for the timely identification of patients in the setting of critical illness. This review will discuss the use of biochemical and electronic biomarkers to allow for prognostic and predictive enrichment of patients with sepsis associated AKI over and above the use of serum creatinine and urine output. Summary: Current data suggest th...
Source: American Journal of Nephrology - October 16, 2023 Category: Urology & Nephrology Authors: Louis Baeseman Samantha Gunning Jay L Koyner Source Type: research
Biomarker Enrichment in Sepsis Associated Acute Kidney Injury: Finding High-Risk Patients in the ICU
Am J Nephrol. 2023 Oct 16. doi: 10.1159/000534608. Online ahead of print.ABSTRACT Abstract: Background: Sepsis associated Acute kidney injury (AKI) is a leading comorbidity in admissions to the intensive care unit. While a gold standard definition exists, it remains imperfect and does not allow for the timely identification of patients in the setting of critical illness. This review will discuss the use of biochemical and electronic biomarkers to allow for prognostic and predictive enrichment of patients with sepsis associated AKI over and above the use of serum creatinine and urine output. Summary: Current data suggest th...
Source: American Journal of Nephrology - October 16, 2023 Category: Urology & Nephrology Authors: Louis Baeseman Samantha Gunning Jay L Koyner Source Type: research
Efficacy and safety of ferric citrate on hyperphosphatemia among Chinese patients with chronic kidney disease undergoing hemodialysis: a phase III multicenter randomized open-label active-drug controlled study
CONCLUSION: Ferric citrate capsules have good efficacy and safety in the control of hyperphosphatemia in adult patients with CKD undergoing hemodialysis. Efficacy is not inferior to sevelamer carbonate. The TEAEs were mostly mild and tolerated by the patients.PMID:37812931 | DOI:10.1159/000534484 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - October 9, 2023 Category: Urology & Nephrology Authors: Yong Wang Xiangmei Chen Hanyu Zhu Zhiyong Guo Yibin Yang Ping Luo Yani He Yan Xu Daxi Ji Xinlu Gao Xiuli Sun Changying Xing Yu Wang Xiaohui Wang Shuping Zhao Yan Guan Hongli Lin Aimin Zhong Hua Shui Fengmin Shao Lu Lv Yuehong Yan Xiaokun Sun Lei Zhang Source Type: research
Urinary Fetuin-A Fragments Predict Progressive eGFR Decline in Two Independent Type 2 Diabetes Cohorts of Different Ethnicities
Conclusion uPTM-FetA was independently associated with kidney function decline in patients with type 2 diabetes validated in a 2-cohort study. The significant additive predictive power of this biomarker from conventional risk factors suggests its clinical use for renal function progression in patients with type 2 diabetes.PMID:37812932 | DOI:10.1159/000534514 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - October 9, 2023 Category: Urology & Nephrology Authors: Gwo-Tsann Chuang Daan Kremer Chi-Hsuan Huang Firas F Alkaff Chih-Hung Lin Tzu-Ling Tseng Gozewijn D Laverman Stephan J L Bakker Lee-Ming Chuang Source Type: research
Efficacy and safety of ferric citrate on hyperphosphatemia among Chinese patients with chronic kidney disease undergoing hemodialysis: a phase III multicenter randomized open-label active-drug controlled study
CONCLUSION: Ferric citrate capsules have good efficacy and safety in the control of hyperphosphatemia in adult patients with CKD undergoing hemodialysis. Efficacy is not inferior to sevelamer carbonate. The TEAEs were mostly mild and tolerated by the patients.PMID:37812931 | DOI:10.1159/000534484 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - October 9, 2023 Category: Urology & Nephrology Authors: Yong Wang Xiangmei Chen Hanyu Zhu Zhiyong Guo Yibin Yang Ping Luo Yani He Yan Xu Daxi Ji Xinlu Gao Xiuli Sun Changying Xing Yu Wang Xiaohui Wang Shuping Zhao Yan Guan Hongli Lin Aimin Zhong Hua Shui Fengmin Shao Lu Lv Yuehong Yan Xiaokun Sun Lei Zhang Source Type: research
Urinary Fetuin-A Fragments Predict Progressive eGFR Decline in Two Independent Type 2 Diabetes Cohorts of Different Ethnicities
Conclusion uPTM-FetA was independently associated with kidney function decline in patients with type 2 diabetes validated in a 2-cohort study. The significant additive predictive power of this biomarker from conventional risk factors suggests its clinical use for renal function progression in patients with type 2 diabetes.PMID:37812932 | DOI:10.1159/000534514 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - October 9, 2023 Category: Urology & Nephrology Authors: Gwo-Tsann Chuang Daan Kremer Chi-Hsuan Huang Firas F Alkaff Chih-Hung Lin Tzu-Ling Tseng Gozewijn D Laverman Stephan J L Bakker Lee-Ming Chuang Source Type: research
Efficacy and safety of ferric citrate on hyperphosphatemia among Chinese patients with chronic kidney disease undergoing hemodialysis: a phase III multicenter randomized open-label active-drug controlled study
CONCLUSION: Ferric citrate capsules have good efficacy and safety in the control of hyperphosphatemia in adult patients with CKD undergoing hemodialysis. Efficacy is not inferior to sevelamer carbonate. The TEAEs were mostly mild and tolerated by the patients.PMID:37812931 | DOI:10.1159/000534484 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - October 9, 2023 Category: Urology & Nephrology Authors: Yong Wang Xiangmei Chen Hanyu Zhu Zhiyong Guo Yibin Yang Ping Luo Yani He Yan Xu Daxi Ji Xinlu Gao Xiuli Sun Changying Xing Yu Wang Xiaohui Wang Shuping Zhao Yan Guan Hongli Lin Aimin Zhong Hua Shui Fengmin Shao Lu Lv Yuehong Yan Xiaokun Sun Lei Zhang Source Type: research
Urinary Fetuin-A Fragments Predict Progressive eGFR Decline in Two Independent Type 2 Diabetes Cohorts of Different Ethnicities
Conclusion uPTM-FetA was independently associated with kidney function decline in patients with type 2 diabetes validated in a 2-cohort study. The significant additive predictive power of this biomarker from conventional risk factors suggests its clinical use for renal function progression in patients with type 2 diabetes.PMID:37812932 | DOI:10.1159/000534514 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - October 9, 2023 Category: Urology & Nephrology Authors: Gwo-Tsann Chuang Daan Kremer Chi-Hsuan Huang Firas F Alkaff Chih-Hung Lin Tzu-Ling Tseng Gozewijn D Laverman Stephan J L Bakker Lee-Ming Chuang Source Type: research
Efficacy and safety of ferric citrate on hyperphosphatemia among Chinese patients with chronic kidney disease undergoing hemodialysis: a phase III multicenter randomized open-label active-drug controlled study
CONCLUSION: Ferric citrate capsules have good efficacy and safety in the control of hyperphosphatemia in adult patients with CKD undergoing hemodialysis. Efficacy is not inferior to sevelamer carbonate. The TEAEs were mostly mild and tolerated by the patients.PMID:37812931 | DOI:10.1159/000534484 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - October 9, 2023 Category: Urology & Nephrology Authors: Yong Wang Xiangmei Chen Hanyu Zhu Zhiyong Guo Yibin Yang Ping Luo Yani He Yan Xu Daxi Ji Xinlu Gao Xiuli Sun Changying Xing Yu Wang Xiaohui Wang Shuping Zhao Yan Guan Hongli Lin Aimin Zhong Hua Shui Fengmin Shao Lu Lv Yuehong Yan Xiaokun Sun Lei Zhang Source Type: research
Urinary Fetuin-A Fragments Predict Progressive eGFR Decline in Two Independent Type 2 Diabetes Cohorts of Different Ethnicities
Conclusion uPTM-FetA was independently associated with kidney function decline in patients with type 2 diabetes validated in a 2-cohort study. The significant additive predictive power of this biomarker from conventional risk factors suggests its clinical use for renal function progression in patients with type 2 diabetes.PMID:37812932 | DOI:10.1159/000534514 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - October 9, 2023 Category: Urology & Nephrology Authors: Gwo-Tsann Chuang Daan Kremer Chi-Hsuan Huang Firas F Alkaff Chih-Hung Lin Tzu-Ling Tseng Gozewijn D Laverman Stephan J L Bakker Lee-Ming Chuang Source Type: research
