Diagnostic yield of exome sequencing in early onset hypertensive nephropathy in adults

CONCLUSIONS: The high diagnostic yield of ES (15%) in a population of patients thought to have HN casts further doubts on the validity of the existing diagnosis criteria, including histological criteria, supposed to characterize the condition. This was especially true in patients with no African ancestry where ES positivity reached 30%.PMID:38471460 | DOI:10.1159/000538173

Source: American Journal of Nephrology - March 12, 2024 Category: Urology & Nephrology Authors: Justine Serre Alice Doreille Laure Raymond Gaspard Suc Micka ël Bobot Marine Dancer C édric Rafat Laurent Mesnard Source Type: research