Health Disparities in Kidney Transplantation for African Americans
Background: The persistent challenges of bridging healthcare disparities for African Americans (AAs) in need of kidney transplantation continue to be unresolved at the national level. This healthcare disparity is multifactorial: stemming from limited kidney donors suitable for AAs; inconsistent care coordination and suboptimal risk factor control; social determinants, low socioeconomic status, reduced access to care; and mistrust of clinicians and the healthcare system.Summary: There are numerous opportunities to significantly lessen the disparities in kidney transplantation for AAs through the following measures: the adop...
Source: American Journal of Nephrology - August 4, 2017 Category: Neurology Source Type: research

Current State and Future Trends to Optimize the Care of African Americans with End-Stage Renal Disease
Background: Chronic kidney disease is a progressive disease, which terminates in end-stage renal diseases (ESRD) that requires either dialysis or kidney transplantation for the patient to survive. There is an alarming trend in the disparities of ESRD in African Americans (AAs). Currently, AAs represent more than 30% of incident ESRD cases, yet they constitute 15% of the overall US population. Despite the reductions in mortality, increases in access to patient-centered home dialysis and preemptive kidney transplantation for the overall US ESRD population over the last decade, disparities in the care of AAs with ESRD remain ...
Source: American Journal of Nephrology - August 4, 2017 Category: Neurology Source Type: research

Impact of Renin-Angiotensin Aldosterone System Inhibition on Serum Potassium Levels among Peritoneal Dialysis Patients
Conclusion: The use of ACEi and ARB was not associated with a greater risk for hyperkalemia in stable peritoneal dialysis patients independently of residual renal function.Am J Nephrol 2017;46:150-155 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 24, 2017 Category: Neurology Source Type: research

Review of Extracorporeal Membrane Oxygenation and Dialysis-Based Liver Support Devices for the Use of Nephrologists.
This article provides a simplified review of the technical aspects of extracorporeal cardiopulmonary and liver support devices used in the adult ICU patient, as well as a summary of the most relevant and up-to-date clinical evidence that supports their use. PMID: 28738354 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 22, 2017 Category: Urology & Nephrology Authors: Hamdi T, Palmer BF Tags: Am J Nephrol Source Type: research

Impact of Renin-Angiotensin Aldosterone System Inhibition on Serum Potassium Levels among Peritoneal Dialysis Patients.
CONCLUSION: The use of ACEi and ARB was not associated with a greater risk for hyperkalemia in stable peritoneal dialysis patients independently of residual renal function. PMID: 28738355 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 22, 2017 Category: Urology & Nephrology Authors: Ribeiro SC, Figueiredo AE, Barretti P, Pecoits-Filho R, de Moraes TP, BRAZPD Investigators Tags: Am J Nephrol Source Type: research

Review of Extracorporeal Membrane Oxygenation and Dialysis-Based Liver Support Devices for the Use of Nephrologists
This article provides a simplified review of the technical aspects of extracorporeal cardiopulmonary and liver support devices used in the adult ICU patient, as well as a summary of the most relevant and up-to-date clinical evidence that supports their use.Am J Nephrol 2017;46:139-149 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 21, 2017 Category: Neurology Source Type: research

Inhibition of Necroptosis Attenuates Kidney Inflammation and Interstitial Fibrosis Induced By Unilateral Ureteral Obstruction.
CONCLUSION: These findings suggest that the participation of necroptosis in UUO is partly demonstrated. And necroptosis inhibition may have a potential role in the treatment of diseases with increased inflammatory response and interstitial fibrosis in renal. PMID: 28723681 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 20, 2017 Category: Urology & Nephrology Authors: Xiao X, Du C, Yan Z, Shi Y, Duan H, Ren Y Tags: Am J Nephrol Source Type: research

Inhibition of Necroptosis Attenuates Kidney Inflammation and Interstitial Fibrosis Induced By Unilateral Ureteral Obstruction
Conclusion: These findings suggest that the participation of necroptosis in UUO is partly demonstrated. And necroptosis inhibition may have a potential role in the treatment of diseases with increased inflammatory response and interstitial fibrosis in renal.Am J Nephrol 2017;46:131-138 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 19, 2017 Category: Neurology Source Type: research

Myeloperoxidase Activity and Oxidized Amino Acids as Biomarkers in Chronic Kidney Disease and Coronary Artery Disease.
PMID: 28715823 [PubMed - in process] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 19, 2017 Category: Urology & Nephrology Authors: Sharma K Tags: Am J Nephrol Source Type: research

Serum Ferritin Variations and Mortality in Incident Hemodialysis Patients.
Abstract BACKGROUND: Higher serum ferritin levels may be influenced by iron use and inflammation, and are associated with higher mortality in hemodialysis (HD) patients. We hypothesized that a major rise in serum ferritin is associated with a higher risk of mortality, irrespective of baseline serum ferritin in incident HD patients. METHODS: In a cohort of 93,979 incident HD patients between 2007 and 2011, we examined the association of change in serum ferritin from the baseline patient quarter (first 91 days from dialysis start) to the subsequent quarter with mortality. Multivariable adjustments were done for...
Source: American Journal of Nephrology - July 14, 2017 Category: Urology & Nephrology Authors: Kim T, Streja E, Soohoo M, Rhee CM, Eriguchi R, Kim TW, Chang TI, Obi Y, Kovesdy CP, Kalantar-Zadeh K Tags: Am J Nephrol Source Type: research

Dialysis in the Elderly and Impact of Institutionalization in the United States Renal Data System.
CONCLUSION: There was increased mortality in institutionalized elderly patients as compared to noninstutionalized elderly patients in the same age group. In accordance with the increased frailty and decreased benefits of therapies in the very elderly, especially in those with additional co-morbidities besides age, palliative and end-of-life care should be considered. PMID: 28704826 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 14, 2017 Category: Urology & Nephrology Authors: Brar A, Mallappallil M, Stefanov DG, Kau D, Salifu MO Tags: Am J Nephrol Source Type: research

Serum Ferritin Variations and Mortality in Incident Hemodialysis Patients
Background: Higher serum ferritin levels may be influenced by iron use and inflammation, and are associated with higher mortality in hemodialysis (HD) patients. We hypothesized that a major rise in serum ferritin is associated with a higher risk of mortality, irrespective of baseline serum ferritin in incident HD patients.Methods: In a cohort of 93,979 incident HD patients between 2007 and 2011, we examined the association of change in serum ferritin from the baseline patient quarter (first 91 days from dialysis start) to the subsequent quarter with mortality. Multivariable adjustments were done for case-mix and markers of...
Source: American Journal of Nephrology - July 13, 2017 Category: Neurology Source Type: research

Dialysis in the Elderly and Impact of Institutionalization in the United States Renal Data System
Conclusion: There was increased mortality in institutionalized elderly patients as compared to noninstutionalized elderly patients in the same age group. In accordance with the increased frailty and decreased benefits of therapies in the very elderly, especially in those with additional co-morbidities besides age, palliative and end-of-life care should be considered.Am J Nephrol 2017;46:114-119 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 13, 2017 Category: Neurology Source Type: research

Immunosuppressive Treatment in C3 Glomerulopathy: Is it Really Effective
Conclusion: Although patients receiving immunosuppressive treatments had higher proteinuria and lower serum albumin at baseline, there were no differences between these patients and those receiving conservative care alone in proteinuria remission or in the decline of renal function. Younger age, higher proteinuria, lower eGFR, and the presence of crescentic and sclerotic glomeruli, severity of interstitial fibrosis, and no remission of proteinuria predicted the progression of kidney disease.Am J Nephrol 2017;46:96-107 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 13, 2017 Category: Neurology Source Type: research

Immunosuppressive Treatment in C3 Glomerulopathy: Time to Reconsider Our Approach.
PMID: 28700984 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 13, 2017 Category: Urology & Nephrology Authors: Tesar V, Hruskova Z Tags: Am J Nephrol Source Type: research

High-Dose Rituximab Ineffective for Focal Segmental Glomerulosclerosis: A Long-Term Observation Study.
CONCLUSIONS: Only a minority (1 of 8) in our series of adult patients with FSGS showed positive effects of high doses of RTX. Future studies are warranted to investigate more promising therapeutic options in the management of FSGS. PMID: 28700988 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 13, 2017 Category: Urology & Nephrology Authors: Roccatello D, Sciascia S, Rossi D, Alpa M, Naretto C, Radin M, Barreca A, Fenoglio R, Baldovino S, Menegatti E Tags: Am J Nephrol Source Type: research

Immunosuppressive Treatment in C3 Glomerulopathy: Is it Really Effective?
CONCLUSION: Although patients receiving immunosuppressive treatments had higher proteinuria and lower serum albumin at baseline, there were no differences between these patients and those receiving conservative care alone in proteinuria remission or in the decline of renal function. Younger age, higher proteinuria, lower eGFR, and the presence of crescentic and sclerotic glomeruli, severity of interstitial fibrosis, and no remission of proteinuria predicted the progression of kidney disease. PMID: 28700996 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 13, 2017 Category: Urology & Nephrology Authors: Caliskan Y, Torun ES, Tiryaki TO, Oruc A, Ozluk Y, Akgul SU, Temurhan S, Oztop N, Kilicaslan I, Sever MS Tags: Am J Nephrol Source Type: research

High-Dose Rituximab Ineffective for Focal Segmental Glomerulosclerosis: A Long-Term Observation Study
Conclusions: Only a minority (1 of 8) in our series of adult patients with FSGS showed positive effects of high doses of RTX. Future studies are warranted to investigate more promising therapeutic options in the management of FSGS.Am J Nephrol 2017;46:108-113 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 12, 2017 Category: Neurology Source Type: research

Immunosuppressive Treatment in C3 Glomerulopathy: Is it Really Effective?
Conclusion: Although patients receiving immunosuppressive treatments had higher proteinuria and lower serum albumin at baseline, there were no differences between these patients and those receiving conservative care alone in proteinuria remission or in the decline of renal function. Younger age, higher proteinuria, lower eGFR, and the presence of crescentic and sclerotic glomeruli, severity of interstitial fibrosis, and no remission of proteinuria predicted the progression of kidney disease.Am J Nephrol 2017;46:96-107 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 12, 2017 Category: Neurology Source Type: research

Immunosuppressive Treatment in C3 Glomerulopathy: Time to Reconsider Our Approach
Am J Nephrol 2017;46:93-95 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 12, 2017 Category: Neurology Source Type: research

High-Performance Membrane Dialyzers and Mortality in Hemodialysis Patients: A 2-Year Cohort Study from the Annual Survey of the Japanese Renal Data Registry
Conclusions: The use of different membrane types may affect mortality. Further long-term prospective studies are needed to clarify whether the PES and PMMA membranes can improve prognosis.Am J Nephrol 2017;46:82-92 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 4, 2017 Category: Neurology Source Type: research

High-Performance Membrane Dialyzers and Mortality in Hemodialysis Patients: A 2-Year Cohort Study from the Annual Survey of the Japanese Renal Data Registry.
CONCLUSIONS: The use of different membrane types may affect mortality. Further long-term prospective studies are needed to clarify whether the PES and PMMA membranes can improve prognosis. PMID: 28675885 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - July 4, 2017 Category: Urology & Nephrology Authors: Abe M, Hamano T, Wada A, Nakai S, Masakane I Tags: Am J Nephrol Source Type: research

Myeloperoxidase Levels and Its Product 3-Chlorotyrosine Predict Chronic Kidney Disease Severity and Associated Coronary Artery Disease.
In this study, we compared myeloperoxidase and protein-bound 3-chlorotyrosine (ClY) levels in subjects with varying degrees of CKD and tested their associations with CAD. METHODS: From Clinical Phenotyping Resource and Biobank Core, 111 patients were selected from CKD stages 1 to 5. Plasma myeloperoxidase level was measured using enzyme-linked-immunosorbent assay. Plasma protein-bound 3-ClY, a specific product of hypochlorous acid generated by myeloperoxidase was measured by liquid chromatography mass spectrometry. RESULTS: We selected 29, 20, 24, 22, and 16 patients from stages 1 to 5 CKD, respectively. In a sex...
Source: American Journal of Nephrology - July 1, 2017 Category: Urology & Nephrology Authors: Afshinnia F, Zeng L, Byun J, Gadegbeku CA, Magnone MC, Whatling C, Valastro B, Kretzler M, Pennathur S, Michigan Kidney Translational Core CPROBE Investigator Group Tags: Am J Nephrol Source Type: research

Myeloperoxidase Activity and Oxidized Amino Acids as Biomarkers in Chronic Kidney Disease and Coronary Artery Disease
Am J Nephrol 2017;46:71-72 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - June 30, 2017 Category: Neurology Source Type: research

Myeloperoxidase Levels and Its Product 3-Chlorotyrosine Predict Chronic Kidney Disease Severity and Associated Coronary Artery Disease
In this study, we compared myeloperoxidase and protein-bound 3-chlorotyrosine (ClY) levels in subjects with varying degrees of CKD and tested their associations with CAD. Methods: From Clinical Phenotyping Resource and Biobank Core, 111 patients were selected from CKD stages 1 to 5. Plasma myeloperoxidase level was measured using enzyme-linked-immunosorbent assay. Plasma protein-bound 3-ClY, a specific product of hypochlorous acid generated by myeloperoxidase was measured by liquid chromatography mass spectrometry.Results: We selected 29, 20, 24, 22, and 16 patients from stages 1 to 5 CKD, respectively. In a sex-adjusted g...
Source: American Journal of Nephrology - June 30, 2017 Category: Neurology Source Type: research

Peritoneal Water Transport Characteristics of Diabetic Patients Undergoing Peritoneal Dialysis: A Longitudinal Study.
CONCLUSIONS: Diabetic patients undergoing PD present lower capacities of ultrafiltration and sodium removal than their nondiabetic counterparts. Longitudinal analyses disclose an essential stability of water transport capacities, both in diabetics and nondiabetics. The clinical significance of these differences deserves further analysis. PMID: 28633134 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - June 21, 2017 Category: Urology & Nephrology Authors: Fernandes A, Ribera-Sanchez R, Rodríguez-Carmona A, López-Iglesias A, Leite-Costa N, Pérez Fontán M Tags: Am J Nephrol Source Type: research

Interaction of Soluble CXC Ligand 16 and Cardiac Injury Markers in Hemodialysis Patients.
Abstract BACKGROUND: Recent data suggest that there is a pathogenic role for CXC ligand 16 (CXCL16) in cardiovascular diseases. Little is known about circulating CXCL16 in patients with kidney dysfunction. We explored the relationships of plasma CXCL16 with cardiac injury markers in a group of dialysis patients. METHODS: Plasma CXCL16 and C-reactive protein (CRP) were measured in 366 patients who were on maintenance hemodialysis. Cardiac injury was evaluated via measurements of the circulating B-type natriuretic peptide (BNP), N-terminal prohormone of brain natriuretic peptide (NT proBNP), Troponin I (TnI), a...
Source: American Journal of Nephrology - June 21, 2017 Category: Urology & Nephrology Authors: Liu W, Wang L, Wei Y, Li X, Gao C, Zhou J, Wang L, Sun Z, Chu H, Bai Y, Yang J Tags: Am J Nephrol Source Type: research

Contents Vol. 45, 2017
Am J Nephrol 2017;45:I-VI (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - June 20, 2017 Category: Neurology Source Type: research

Interaction of Soluble CXC Ligand 16 and Cardiac Injury Markers in Hemodialysis Patients
Background: Recent data suggest that there is a pathogenic role for CXC ligand 16 (CXCL16) in cardiovascular diseases. Little is known about circulating CXCL16 in patients with kidney dysfunction. We explored the relationships of plasma CXCL16 with cardiac injury markers in a group of dialysis patients.Methods: Plasma CXCL16 and C-reactive protein (CRP) were measured in 366 patients who were on maintenance hemodialysis. Cardiac injury was evaluated via measurements of the circulating B-type natriuretic peptide (BNP), N-terminal prohormone of brain natriuretic peptide (NT proBNP), Troponin I (TnI), and Troponin T (TnT). Six...
Source: American Journal of Nephrology - June 20, 2017 Category: Neurology Source Type: research

Peritoneal Water Transport Characteristics of Diabetic Patients Undergoing Peritoneal Dialysis: A Longitudinal Study
Conclusions: Diabetic patients undergoing PD present lower capacities of ultrafiltration and sodium removal than their nondiabetic counterparts. Longitudinal analyses disclose an essential stability of water transport capacities, both in diabetics and nondiabetics. The clinical significance of these differences deserves further analysis.Am J Nephrol 2017;46:47-54 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - June 20, 2017 Category: Neurology Source Type: research

Identification of 8 Novel Mutations in Nephrogenesis-Related Genes in Chinese Han Patients with Unilateral Renal Agenesis.
Abstract BACKGROUND: Few genetic studies have focused on unilateral renal agenesis (URA), which is a disorder with insidious clinical manifestations and a tendency to result in renal failure. We aimed to detect pathogenic mutations in nephrogenesis-related genes, which were identified by a literature review conducted among a large cohort of Chinese Han patients with URA. METHODS: Totally, 86 unrelated URA patients were included. All URA patients were diagnosed by employing radiological methods. Patients with a solitary kidney owing to nephrectomy or renal atrophy due to secondary factors were excluded. Nine (...
Source: American Journal of Nephrology - June 16, 2017 Category: Urology & Nephrology Authors: Wu H, Xu Q, Xie J, Ma J, Qiao P, Zhang W, Yu H, Wang W, Qian Y, Zhang Q, Guo Y, Tang Y, Chen XN, Wang Z, Chen N Tags: Am J Nephrol Source Type: research

Identification of 8 Novel Mutations in Nephrogenesis-Related Genes in Chinese Han Patients with Unilateral Renal Agenesis
Background: Few genetic studies have focused on unilateral renal agenesis (URA), which is a disorder with insidious clinical manifestations and a tendency to result in renal failure. We aimed to detect pathogenic mutations in nephrogenesis-related genes, which were identified by a literature review conducted among a large cohort of Chinese Han patients with URA.Methods: Totally, 86 unrelated URA patients were included. All URA patients were diagnosed by employing radiological methods. Patients with a solitary kidney owing to nephrectomy or renal atrophy due to secondary factors were excluded. Nine (10.5%) patients had a fa...
Source: American Journal of Nephrology - June 15, 2017 Category: Neurology Source Type: research

Vascular Calcification and Osteoprotegrin in Chronic Kidney Disease.
PMID: 28614808 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - June 15, 2017 Category: Urology & Nephrology Authors: Lenhard MJ, Maser RE Tags: Am J Nephrol Source Type: research

Osteoprotegerin Is the Strongest Predictor for Progression of Arterial Calcification in Peritoneal Dialysis Patients.
Abstract BACKGROUND: Arterial calcification (AC) is frequent in patients with end stage renal disease and is also considered a risk factor for later morbidity and mortality. However, long-term factors associated with the process are not well known. We analyzed the trends over time of biomarkers related with development and progression of AC in incident patients on peritoneal dialysis (PD). METHODS: We performed a prospective study with 186 patients on PD followed up for 1 year. We analyzed the progression of AC in the abdominal aorta and pelvic vessels by calcification score (CaSc), using16-cut computerized m...
Source: American Journal of Nephrology - June 15, 2017 Category: Urology & Nephrology Authors: Avila M, Mora C, Prado MDC, Zavala M, Paniagua R, Mexican Collaborative Group Tags: Am J Nephrol Source Type: research

Osteoprotegerin Is the Strongest Predictor for Progression of Arterial Calcification in Peritoneal Dialysis Patients
Background: Arterial calcification (AC) is frequent in patients with end stage renal disease and is also considered a risk factor for later morbidity and mortality. However, long-term factors associated with the process are not well known. We analyzed the trends over time of biomarkers related with development and progression of AC in incident patients on peritoneal dialysis (PD).Methods: We performed a prospective study with 186 patients on PD followed up for 1 year. We analyzed the progression of AC in the abdominal aorta and pelvic vessels by calcification score (CaSc), using16-cut computerized multidetector tomography ...
Source: American Journal of Nephrology - June 14, 2017 Category: Neurology Source Type: research

Vascular Calcification and Osteoprotegrin in Chronic Kidney Disease
Am J Nephrol 2017;46:37-38 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - June 14, 2017 Category: Neurology Source Type: research

Validation of Surrogates of Urine Osmolality in Population Studies.
CONCLUSION: The eUosm is a valid marker of urine concentration in population-based and CKD cohorts. The UCI can provide an estimate of urine concentration when no other measurement is available, but should be used only in subjects with normal renal function. PMID: 28586769 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - June 7, 2017 Category: Urology & Nephrology Authors: Youhanna S, Bankir L, Jungers P, Porteous D, Polasek O, Bochud M, Hayward C, Devuyst O Tags: Am J Nephrol Source Type: research

Validation of Surrogates of Urine Osmolality in Population Studies
Conclusion: The eUosm is a valid marker of urine concentration in population-based and CKD cohorts. The UCI can provide an estimate of urine concentration when no other measurement is available, but should be used only in subjects with normal renal function.Am J Nephrol 2017;46:26-36 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - June 6, 2017 Category: Neurology Source Type: research

Impact of Diabetes on Extracellular Volume Status in Patients Initiating Peritoneal Dialysis
Background: Recent reports have highlighted that diabetic patients with kidney failure are at increased risk of technique failure and transfer to haemodialysis within 90 days of initiating peritoneal dialysis (PD). We wished to determine whether there were differences between diabetic and non-diabetic patients within the first 3 months of starting PD.Methods: We reviewed results of corresponding bioimpedance and the 1st test of peritoneal membrane function (PET) in consecutive patients, 6-10 weeks after initiating PD electively.Results: Adult patients numbering 386 - 230 males (59.6%), 152 (39.4%) diabetic, 188 (48.7%) whi...
Source: American Journal of Nephrology - June 1, 2017 Category: Neurology Source Type: research

Erythropoietin Hyporesponsiveness in Dialysis Patients: Possible Role of Statins
Conclusions: Our results suggest that statins may slightly reduce ESA hyporesponsiveness in HD patients. However, any causal inference is limited by the observational study design and unmeasured compliance with statin Rx.Am J Nephrol 2017;46:11-17 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - June 1, 2017 Category: Neurology Source Type: research

Impact of Diabetes on Extracellular Volume Status in Patients Initiating Peritoneal Dialysis.
Abstract BACKGROUND: Recent reports have highlighted that diabetic patients with kidney failure are at increased risk of technique failure and transfer to haemodialysis within 90 days of initiating peritoneal dialysis (PD). We wished to determine whether there were differences between diabetic and non-diabetic patients within the first 3 months of starting PD. METHODS: We reviewed results of corresponding bioimpedance and the 1st test of peritoneal membrane function (PET) in consecutive patients, 6-10 weeks after initiating PD electively. RESULTS: Adult patients numbering 386 - 230 males (59.6%), 152 (39...
Source: American Journal of Nephrology - June 1, 2017 Category: Urology & Nephrology Authors: Udo A, Goodlad C, Davenport A Tags: Am J Nephrol Source Type: research

Erythropoietin Hyporesponsiveness in Dialysis Patients: Possible Role of Statins.
CONCLUSIONS: Our results suggest that statins may slightly reduce ESA hyporesponsiveness in HD patients. However, any causal inference is limited by the observational study design and unmeasured compliance with statin Rx. PMID: 28564644 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - June 1, 2017 Category: Urology & Nephrology Authors: Hasegawa T, Zhao J, Fuller DS, Bieber B, Zee J, Morgenstern H, Hanafusa N, Nangaku M Tags: Am J Nephrol Source Type: research

How Do We Improve the Quality of Life of Haemodialysis Patients Now That's a Good Question
Am J Nephrol 2017;46:1-2 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - May 30, 2017 Category: Neurology Source Type: research

How Do We Improve the Quality of Life of Haemodialysis Patients? Now That's a Good Question.
PMID: 28554170 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - May 30, 2017 Category: Urology & Nephrology Authors: Rayner HC Tags: Am J Nephrol Source Type: research

Modification of Potassium-Mortality Relationship by Ethnicity and Race: Solving the Puzzle.
PMID: 28554175 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - May 30, 2017 Category: Urology & Nephrology Authors: Agarwal R Tags: Am J Nephrol Source Type: research

Higher Ultrafiltration Rate Is Associated with Longer Dialysis Recovery Time in Patients Undergoing Conventional Hemodialysis.
We examined the association of 30-day average UFR with recovery time. RESULTS: The total number of patients included in this study was 2,689. DRT in categories of immediate recovery,>0-≤2,>2-≤6,>6-≤12, and>12 h, were reported in 27, 28, 17, 9, and 20% of the patients respectively. In multivariable analysis, longer DRT was associated with female gender, non-black race, higher body weight, lower serum albumin, chronic heart failure, cerebrovascular disease, missed dialysis sessions, higher pre-dialysis systolic blood pressure, and larger UF volume. Compared to UFR of
Source: American Journal of Nephrology - May 30, 2017 Category: Urology & Nephrology Authors: Hussein WF, Arramreddy R, Sun SJ, Reiterman M, Schiller B Tags: Am J Nephrol Source Type: research

Higher Ultrafiltration Rate Is Associated with Longer Dialysis Recovery Time in Patients Undergoing Conventional Hemodialysis
We examined the association of 30-day average UFR with recovery time.Results: The total number of patients included in this study was 2,689. DRT in categories of immediate recovery,>0- ≤2,>2- ≤6,>6- ≤12, and>12 h, were reported in 27, 28, 17, 9, and 20% of the patients respectively. In multivariable analysis, longer DRT was associated with female gender, non-black race, higher body weight, lower serum albumin, chronic heart failure, cerebrovascular disease, missed dialysis sessions, higher pre-dialysis systolic blood pressure, and larger UF volume. Compared to UFR of (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - May 29, 2017 Category: Neurology Source Type: research

How Do We Improve the Quality of Life of Haemodialysis Patients? Now That's a Good Question
Am J Nephrol 2017;46:1-2 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - May 29, 2017 Category: Neurology Source Type: research

Modification of Potassium-Mortality Relationship by Ethnicity and Race: Solving the Puzzle
Am J Nephrol 2017;45:552-554 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - May 29, 2017 Category: Neurology Source Type: research

On the Right Track: Implementing Interventions to Reduce Readmissions in Dialysis Patients.
PMID: 28538222 [PubMed - as supplied by publisher] (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - May 25, 2017 Category: Urology & Nephrology Authors: Plantinga LC, Jaar BG Tags: Am J Nephrol Source Type: research