Green tea polyphenols alleviate kidney injury induced by di(2-ethylhexyl) phthalate in mice
CONCLUSION: GTP can alleviate DEHP-induced kidney damage and regulate immune cell infiltration. We screened four important miRNA-mRNA-protein regulatory axes of GTP mitigating DEHP-induced kidney damage in mice.PMID:37734331 | DOI:10.1159/000534106 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 21, 2023 Category: Urology & Nephrology Authors: Heng Shi Xinhai Zhao Peng Qin Xianling Zhou Sisi Liu Chuanchuan Sun Qiuyu Cao Shiping Zhu Shengyun Sun Source Type: research

Green tea polyphenols alleviate kidney injury induced by di(2-ethylhexyl) phthalate in mice
CONCLUSION: GTP can alleviate DEHP-induced kidney damage and regulate immune cell infiltration. We screened four important miRNA-mRNA-protein regulatory axes of GTP mitigating DEHP-induced kidney damage in mice.PMID:37734331 | DOI:10.1159/000534106 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 21, 2023 Category: Urology & Nephrology Authors: Heng Shi Xinhai Zhao Peng Qin Xianling Zhou Sisi Liu Chuanchuan Sun Qiuyu Cao Shiping Zhu Shengyun Sun Source Type: research

Green tea polyphenols alleviate kidney injury induced by di(2-ethylhexyl) phthalate in mice
CONCLUSION: GTP can alleviate DEHP-induced kidney damage and regulate immune cell infiltration. We screened four important miRNA-mRNA-protein regulatory axes of GTP mitigating DEHP-induced kidney damage in mice.PMID:37734331 | DOI:10.1159/000534106 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 21, 2023 Category: Urology & Nephrology Authors: Heng Shi Xinhai Zhao Peng Qin Xianling Zhou Sisi Liu Chuanchuan Sun Qiuyu Cao Shiping Zhu Shengyun Sun Source Type: research

Green tea polyphenols alleviate kidney injury induced by di(2-ethylhexyl) phthalate in mice
CONCLUSION: GTP can alleviate DEHP-induced kidney damage and regulate immune cell infiltration. We screened four important miRNA-mRNA-protein regulatory axes of GTP mitigating DEHP-induced kidney damage in mice.PMID:37734331 | DOI:10.1159/000534106 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 21, 2023 Category: Urology & Nephrology Authors: Heng Shi Xinhai Zhao Peng Qin Xianling Zhou Sisi Liu Chuanchuan Sun Qiuyu Cao Shiping Zhu Shengyun Sun Source Type: research

Racial Disparities in End-Stage Kidney Disease Outcomes Among Asians and Native Hawaiians and Other Pacific Islanders Across Geographic Residence
CONCLUSION: In the Mainland, Asians and NHOPIs had lower mortality vs. White patients, whereas in Hawaii/PIs this survival benefit was diminished in Asians and mitigated in NHOPIs. NHOPIs and Asians in Hawaii/PIs had less transplantation vs. those in the Mainland. Further research is needed to uncover factors contributing to differential ESKD outcomes among Asians and NHOPIs across geographic residence.PMID:37725913 | DOI:10.1159/000534052 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 19, 2023 Category: Urology & Nephrology Authors: Amy S You Keith C Norris Merle Kataoka-Yahiro James Davis Victoria Page Glen Hayashida Yoko Narasaki Shiuh Feng Cheng Roland Ng Linda L Wong Felix Lee Kamyar Kalantar-Zadeh Connie M Rhee Source Type: research

Maintaining renin-angiotensin-aldosterone system inhibitor treatment with patiromer in hyperkalaemic chronic kidney disease patients: comparison of a propensity-matched real-world population with AMETHYST-DN
CONCLUSIONS: These results demonstrate the benefit of patiromer for sK+ management to enable RAASi use, while revealing beneficial effects on BP.PMID:37725919 | DOI:10.1159/000533753 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 19, 2023 Category: Urology & Nephrology Authors: Rajkumar Chinnadurai Sharmilee Rengarajan Jeffrey J Budden Carol Moreno Quinn Philip A Kalra Source Type: research

Clinicopathological Features and Outcomes of IgA Nephropathy with Serum Antineutrophil Cytoplasmic Autoantibody Positivity
CONCLUSION: The clinical, pathological features and prognosis of ANCA-positive IgAN patients were similar with ANCA-negative IgAN patients except for higher ANA positive rate, milder renal inflammation and less immune depositions. ANA positivity was an independent risk factor for adverse renal outcomes in ANCA-positive IgAN patients.PMID:37725925 | DOI:10.1159/000533982 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 19, 2023 Category: Urology & Nephrology Authors: Wenchao Li Ruifan Chen Wei Chen Fengxian Huang Xi Xia Source Type: research

Racial Disparities in End-Stage Kidney Disease Outcomes Among Asians and Native Hawaiians and Other Pacific Islanders Across Geographic Residence
CONCLUSION: In the Mainland, Asians and NHOPIs had lower mortality vs. White patients, whereas in Hawaii/PIs this survival benefit was diminished in Asians and mitigated in NHOPIs. NHOPIs and Asians in Hawaii/PIs had less transplantation vs. those in the Mainland. Further research is needed to uncover factors contributing to differential ESKD outcomes among Asians and NHOPIs across geographic residence.PMID:37725913 | DOI:10.1159/000534052 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 19, 2023 Category: Urology & Nephrology Authors: Amy S You Keith C Norris Merle Kataoka-Yahiro James Davis Victoria Page Glen Hayashida Yoko Narasaki Shiuh Feng Cheng Roland Ng Linda L Wong Felix Lee Kamyar Kalantar-Zadeh Connie M Rhee Source Type: research

Maintaining renin-angiotensin-aldosterone system inhibitor treatment with patiromer in hyperkalaemic chronic kidney disease patients: comparison of a propensity-matched real-world population with AMETHYST-DN
CONCLUSIONS: These results demonstrate the benefit of patiromer for sK+ management to enable RAASi use, while revealing beneficial effects on BP.PMID:37725919 | DOI:10.1159/000533753 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 19, 2023 Category: Urology & Nephrology Authors: Rajkumar Chinnadurai Sharmilee Rengarajan Jeffrey J Budden Carol Moreno Quinn Philip A Kalra Source Type: research

Clinicopathological Features and Outcomes of IgA Nephropathy with Serum Antineutrophil Cytoplasmic Autoantibody Positivity
CONCLUSION: The clinical, pathological features and prognosis of ANCA-positive IgAN patients were similar with ANCA-negative IgAN patients except for higher ANA positive rate, milder renal inflammation and less immune depositions. ANA positivity was an independent risk factor for adverse renal outcomes in ANCA-positive IgAN patients.PMID:37725925 | DOI:10.1159/000533982 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 19, 2023 Category: Urology & Nephrology Authors: Wenchao Li Ruifan Chen Wei Chen Fengxian Huang Xi Xia Source Type: research

Clinicopathological characteristics and prognosis of lupus nephritis patients with acute kidney injury
CONCLUSIONS: LN patients with AKI stage 3, but not stage 1 and 2, have poorer long-term renal outcomes and patient survival. Our study demonstrates the importance of early identification and management of AKI in LN patients.PMID:37708856 | DOI:10.1159/000533847 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 14, 2023 Category: Urology & Nephrology Authors: Suchun Li Qimei Luo Yuting Fan Chen Zhao Fengxian Huang Xi Xia Wei Chen Source Type: research

Cardiorenal Outcomes with Finerenone in Asian Patients with Chronic Kidney Disease and Type 2 Diabetes: A FIDELIO-DKD post hoc Analysis
CONCLUSION: Finerenone produces similar cardiorenal benefits in Asian and non-Asian patients.PMID:37708857 | DOI:10.1159/000532102 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 14, 2023 Category: Urology & Nephrology Authors: Daisuke Koya Stefan D Anker Luis M Ruilope Peter Rossing ZhiHong Liu Byung Wan Lee Chien-Te Lee Charlie Scott Peter Kolkhof Robert Lawatscheck Lili Wang Amer Joseph Bertram Pitt FIDELIO-DKD Investigators Source Type: research

Renal outcomes in older adults with antineutrophil cytoplasmic autoantibody-associated vasculitis: a new prediction model
CONCLUSION: We established a risk-scoring system based on baseline clinical characteristics to predict composite renal outcomes in patients with AAV. Our results suggest that more attention should be paid to older patients with severe renal impairment and active inflammation.PMID:37708862 | DOI:10.1159/000533512 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 14, 2023 Category: Urology & Nephrology Authors: Shuo Zhang Xin Chen Zuoxian Hou Peng Xia Xiaoxiao Shi Haiting Wu Yubing Wen Yan Qin Xinping Tian Limeng Chen Source Type: research

Clinicopathological characteristics and prognosis of lupus nephritis patients with acute kidney injury
CONCLUSIONS: LN patients with AKI stage 3, but not stage 1 and 2, have poorer long-term renal outcomes and patient survival. Our study demonstrates the importance of early identification and management of AKI in LN patients.PMID:37708856 | DOI:10.1159/000533847 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 14, 2023 Category: Urology & Nephrology Authors: Suchun Li Qimei Luo Yuting Fan Chen Zhao Fengxian Huang Xi Xia Wei Chen Source Type: research

Cardiorenal Outcomes with Finerenone in Asian Patients with Chronic Kidney Disease and Type 2 Diabetes: A FIDELIO-DKD post hoc Analysis
CONCLUSION: Finerenone produces similar cardiorenal benefits in Asian and non-Asian patients.PMID:37708857 | DOI:10.1159/000532102 (Source: American Journal of Nephrology)
Source: American Journal of Nephrology - September 14, 2023 Category: Urology & Nephrology Authors: Daisuke Koya Stefan D Anker Luis M Ruilope Peter Rossing ZhiHong Liu Byung Wan Lee Chien-Te Lee Charlie Scott Peter Kolkhof Robert Lawatscheck Lili Wang Amer Joseph Bertram Pitt FIDELIO-DKD Investigators Source Type: research