Potential role of microRNAs in personalized medicine against hepatitis: a futuristic approach
AbstractMicroRNAs (miRNAs) have been the subject of extensive research for many years, primarily in the context of diseases such as cancer. However, our appreciation of their significance in viral infections, particularly in hepatitis, has increased due to the discovery of their association with both the host and the virus. Hepatitis is a major global health concern and can be caused by various viruses,  including hepatitis A to E. This review highlights the key factors associated with miRNAs and their involvement in infections with various viruses that cause hepatitis. The review not only emphasizes the expression profil...
Source: Archives of Virology - January 21, 2024 Category: Virology Source Type: research

Atypical Presentation of Hepatitis A Infection in an Infant
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - January 18, 2024 Category: Pediatrics Source Type: research

Drug induced autoimmune hepatitis: An unfortunate case of herbal toxicity from Skullcap supplement: A case report
CONCLUSION: This scenario highlights an uncommon instance of DILI caused by Skullcap supplements. It's crucial for hepatologists to recognize this connection due to the increasing prevalence of herbal supplements.PMID:38223420 | PMC:PMC10784811 | DOI:10.4254/wjh.v15.i12.1333 (Source: World Journal of Hepatology)
Source: World Journal of Hepatology - January 15, 2024 Category: Gastroenterology Authors: Nimish Thakral Venkata Rajesh Konjeti Fady William Salama Source Type: research

In-house RT-PCR detection of hepatitis A virus in human plasma pools used for the manufacture of medicinal products
Hepatitis A virus (HAV) is the most frequent cause of viral hepatitis worldwide and is transmitted through the fecal-oral route. However, HAV can also be transmitted by blood-derived products. This is due to the fact that viremia occurs during the asymptomatic phase of HAV infection, enabling infected blood or plasma donations to occur. Viral inactivation/removal steps are included during manufacturing of plasmaderived products. However, HAV is a small non-enveloped virus very difficult to remove with traditional viral inactivation procedures. (Source: Transfusion and Apheresis Science)
Source: Transfusion and Apheresis Science - January 12, 2024 Category: Hematology Authors: Luciana Sampieri, Gonzalo Rodr íguez-Lombardi, María Eugenia Bernardi Source Type: research

Foodborne Viruses and Somatic Coliphages Occurrence in Fresh Produce at Retail from Northern Mexico
This study aimed to establish the occurrence and correlation of foodborne viruses and somatic coliphages in leafy greens in northern Mexico. A total of 320 vegetable samples were collected, resulting in 80 composite rinses, 40 of lettuce and 40 of parsley. Somatic coliphages were determined using the EPA 1602 method, while foodborne viruses (HAV, RoV, NoV GI, and GII) were determined by qPCR. The occurrence of RoV was 22.5% (9/40, mean 2.11 log gc/g) in lettuce and 20% (8/40, mean 1.91 log gc/g) in parsley. NoV and HAV were not detected in any samples. Somatic coliphages were present in all lettuce and parsley samples, wit...
Source: Food and Environmental Virology - January 10, 2024 Category: Virology Source Type: research

Real-World Safety and Effectiveness of an 8-Week Regimen of Glecaprevir/Pibrentasvir in Patients with Hepatitis  C and Cirrhosis
CONCLUSION: An 8-week regimen of GLE/PIB is well tolerated and highly effective among US patients with HCV and cirrhosis receiving routine clinical care.PMID:38169058 | DOI:10.1007/s12325-023-02748-y (Source: Adv Data)
Source: Adv Data - January 3, 2024 Category: Epidemiology Authors: Mei Lu Loralee B Rupp Christina Melkonian Sheri Trudeau Yihe G Daida Mark A Schmidt Stuart C Gordon Source Type: research

Real-World Safety and Effectiveness of an 8-Week Regimen of Glecaprevir/Pibrentasvir in Patients with Hepatitis  C and Cirrhosis
CONCLUSION: An 8-week regimen of GLE/PIB is well tolerated and highly effective among US patients with HCV and cirrhosis receiving routine clinical care.PMID:38169058 | DOI:10.1007/s12325-023-02748-y (Source: Adv Data)
Source: Adv Data - January 3, 2024 Category: Epidemiology Authors: Mei Lu Loralee B Rupp Christina Melkonian Sheri Trudeau Yihe G Daida Mark A Schmidt Stuart C Gordon Source Type: research

Real-World Safety and Effectiveness of an 8-Week Regimen of Glecaprevir/Pibrentasvir in Patients with Hepatitis  C and Cirrhosis
ConclusionAn 8-week regimen of GLE/PIB is well tolerated and highly effective among US patients with HCV and cirrhosis receiving routine clinical care. (Source: Advances in Therapy)
Source: Advances in Therapy - January 2, 2024 Category: Drugs & Pharmacology Source Type: research

Hepatitis  C in prisons : Treatment and barriers to the elimination goals of the United Nations
CONCLUSIONS: Comprehensive education and counselling on HCV treatment, consistent HCV testing and treatment, and preventive measures to avoid (re-)infection are important for successful HCV elimination in prisons.PMID:38155308 | DOI:10.1007/s00103-023-03808-y (Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz)
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - December 28, 2023 Category: International Medicine & Public Health Authors: Anna Dichtl Daniela Jamin Heino St över Meryem Grabski B ärbel Knorr Source Type: research

Hepatitis  C in prisons : Treatment and barriers to the elimination goals of the United Nations
CONCLUSIONS: Comprehensive education and counselling on HCV treatment, consistent HCV testing and treatment, and preventive measures to avoid (re-)infection are important for successful HCV elimination in prisons.PMID:38155308 | DOI:10.1007/s00103-023-03808-y (Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz)
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - December 28, 2023 Category: International Medicine & Public Health Authors: Anna Dichtl Daniela Jamin Heino St över Meryem Grabski B ärbel Knorr Source Type: research

Hepatitis  C in prisons : Treatment and barriers to the elimination goals of the United Nations
CONCLUSIONS: Comprehensive education and counselling on HCV treatment, consistent HCV testing and treatment, and preventive measures to avoid (re-)infection are important for successful HCV elimination in prisons.PMID:38155308 | DOI:10.1007/s00103-023-03808-y (Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz)
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - December 28, 2023 Category: International Medicine & Public Health Authors: Anna Dichtl Daniela Jamin Heino St över Meryem Grabski B ärbel Knorr Source Type: research

Hepatitis  C in prisons : Treatment and barriers to the elimination goals of the United Nations
CONCLUSIONS: Comprehensive education and counselling on HCV treatment, consistent HCV testing and treatment, and preventive measures to avoid (re-)infection are important for successful HCV elimination in prisons.PMID:38155308 | DOI:10.1007/s00103-023-03808-y (Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz)
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - December 28, 2023 Category: International Medicine & Public Health Authors: Anna Dichtl Daniela Jamin Heino St över Meryem Grabski B ärbel Knorr Source Type: research

Hepatitis  C in prisons : Treatment and barriers to the elimination goals of the United Nations
CONCLUSIONS: Comprehensive education and counselling on HCV treatment, consistent HCV testing and treatment, and preventive measures to avoid (re-)infection are important for successful HCV elimination in prisons.PMID:38155308 | DOI:10.1007/s00103-023-03808-y (Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz)
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - December 28, 2023 Category: International Medicine & Public Health Authors: Anna Dichtl Daniela Jamin Heino St över Meryem Grabski B ärbel Knorr Source Type: research

Hepatitis  C in prisons : Treatment and barriers to the elimination goals of the United Nations
CONCLUSIONS: Comprehensive education and counselling on HCV treatment, consistent HCV testing and treatment, and preventive measures to avoid (re-)infection are important for successful HCV elimination in prisons.PMID:38155308 | DOI:10.1007/s00103-023-03808-y (Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz)
Source: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz - December 28, 2023 Category: International Medicine & Public Health Authors: Anna Dichtl Daniela Jamin Heino St över Meryem Grabski B ärbel Knorr Source Type: research

Community burden of hepatitis A infection and risk of transmission in Hong Kong
Hong Kong Med J. 2023 Dec;29 Suppl 7(6):41-46.NO ABSTRACTPMID:38148657 (Source: Hong Kong Med J)
Source: Hong Kong Med J - December 27, 2023 Category: General Medicine Authors: N S Wong D P C Chan C P Chan C M Poon S S Lee Source Type: research