Preventable Deaths During Widespread Community Hepatitis A Outbreaks - United States, 2016-2022
MMWR Morb Mortal Wkly Rep. 2023 Oct 20;72(42):1128-1133. doi: 10.15585/mmwr.mm7242a1.ABSTRACTHepatitis A is acquired through the fecal-oral route and is preventable by a safe and effective vaccine. Although hepatitis A is generally mild and self-limited, serious complications, including death, can occur. Since 2016, widespread hepatitis A outbreaks have been reported in 37 U.S. states, primarily among persons who use drugs and those experiencing homelessness. Nearly twice as many hepatitis A-related deaths were reported during 2016-2022 compared with 2009-2015. CDC analyzed data from 27 hepatitis A outbreak-affected states...
Source: MMWR Morb Mortal Wkl... - October 19, 2023 Category: Epidemiology Authors: Megan G Hofmeister Neil Gupta Hepatitis A Mortality Investigators Source Type: research
Preventable Deaths During Widespread Community Hepatitis A Outbreaks - United States, 2016-2022
MMWR Morb Mortal Wkly Rep. 2023 Oct 20;72(42):1128-1133. doi: 10.15585/mmwr.mm7242a1.ABSTRACTHepatitis A is acquired through the fecal-oral route and is preventable by a safe and effective vaccine. Although hepatitis A is generally mild and self-limited, serious complications, including death, can occur. Since 2016, widespread hepatitis A outbreaks have been reported in 37 U.S. states, primarily among persons who use drugs and those experiencing homelessness. Nearly twice as many hepatitis A-related deaths were reported during 2016-2022 compared with 2009-2015. CDC analyzed data from 27 hepatitis A outbreak-affected states...
Source: MMWR Morb Mortal Wkl... - October 19, 2023 Category: Epidemiology Authors: Megan G Hofmeister Neil Gupta Hepatitis A Mortality Investigators Source Type: research
Microbiological and physicochemical quality enhancement of treated wastewater using raw and chemically modified clays from Sidi Bouzid region, Tunisia
This study firstly evaluates the microbiological and physicochemical quality of treated wastewaters collected from two wastewater treatment plants (WWTPs) located in two different Tunisian cities namely Sidi Bouzid (SB) and Gafsa (G). Then, the capacity of three raw and acid/base-activated local clays to enhance the quality of wastewaters was assessed. The results indicate that the quantities of enteric bacteria (oscillating from 1.381 × 103 to 1.4 × 108 CFU/100 mL), fungi (between 1.331 × 103 and 1.781 × 104 CFU/100 mL), as well as SARS-CoV-2 (between 4.25 × 103 and 5.05 × 105 CFU/100 mL) and Hepatitis A virus RNA (...
Source: Environmental Research - October 18, 2023 Category: Environmental Health Authors: Hakima Gharbi-Khelifi Habib Jmii Mohamed Mosbahi Samiha Hamdi Rawand Hamdi Jihen Brahmi Slim Loukil Mohamed Chamkha Sami Sayadi Mahjoub Aouni Ana Barreiro Maria J Fern ández-Sanjurjo Avelino N úñez-Delgado Esperanza Álvarez Rodríguez Source Type: research
Microbiological and physicochemical quality enhancement of treated wastewater using raw and chemically modified clays from Sidi Bouzid region, Tunisia
This study firstly evaluates the microbiological and physicochemical quality of treated wastewaters collected from two wastewater treatment plants (WWTPs) located in two different Tunisian cities namely Sidi Bouzid (SB) and Gafsa (G). Then, the capacity of three raw and acid/base-activated local clays to enhance the quality of wastewaters was assessed. The results indicate that the quantities of enteric bacteria (oscillating from 1.381 × 103 to 1.4 × 108 CFU/100 mL), fungi (between 1.331 × 103 and 1.781 × 104 CFU/100 mL), as well as SARS-CoV-2 (between 4.25 × 103 and 5.05 × 105 CFU/100 mL) and Hepatitis A virus RNA (...
Source: Environmental Research - October 18, 2023 Category: Environmental Health Authors: Hakima Gharbi-Khelifi Habib Jmii Mohamed Mosbahi Samiha Hamdi Rawand Hamdi Jihen Brahmi Slim Loukil Mohamed Chamkha Sami Sayadi Mahjoub Aouni Ana Barreiro Maria J Fern ández-Sanjurjo Avelino N úñez-Delgado Esperanza Álvarez Rodríguez Source Type: research
The Ill Returning Traveler
Am Fam Physician. 2023 Oct;108(4):396-403.ABSTRACTApproximately 1.8 billion people will cross an international border by 2030, and 66% of travelers will develop a travel-related illness. Most travel-related illnesses are self-limiting and do not require significant intervention; others could cause significant morbidity or mortality. Physicians should begin with a thorough history and clinical examination to have the highest probability of making the correct diagnosis. Targeted questioning should focus on the type of trip taken, the travel itinerary, and a list of all geographic locations visited. Inquiries should also be m...
Source: American Family Physician - October 16, 2023 Category: Primary Care Authors: Nicholas A Rathjen S David Shahbodaghi Source Type: research
The Ill Returning Traveler
Am Fam Physician. 2023 Oct;108(4):396-403.ABSTRACTApproximately 1.8 billion people will cross an international border by 2030, and 66% of travelers will develop a travel-related illness. Most travel-related illnesses are self-limiting and do not require significant intervention; others could cause significant morbidity or mortality. Physicians should begin with a thorough history and clinical examination to have the highest probability of making the correct diagnosis. Targeted questioning should focus on the type of trip taken, the travel itinerary, and a list of all geographic locations visited. Inquiries should also be m...
Source: American Family Physician - October 16, 2023 Category: Primary Care Authors: Nicholas A Rathjen S David Shahbodaghi Source Type: research
The Ill Returning Traveler
Am Fam Physician. 2023 Oct;108(4):396-403.ABSTRACTApproximately 1.8 billion people will cross an international border by 2030, and 66% of travelers will develop a travel-related illness. Most travel-related illnesses are self-limiting and do not require significant intervention; others could cause significant morbidity or mortality. Physicians should begin with a thorough history and clinical examination to have the highest probability of making the correct diagnosis. Targeted questioning should focus on the type of trip taken, the travel itinerary, and a list of all geographic locations visited. Inquiries should also be m...
Source: American Family Physician - October 16, 2023 Category: Primary Care Authors: Nicholas A Rathjen S David Shahbodaghi Source Type: research
The Ill Returning Traveler
Am Fam Physician. 2023 Oct;108(4):396-403.ABSTRACTApproximately 1.8 billion people will cross an international border by 2030, and 66% of travelers will develop a travel-related illness. Most travel-related illnesses are self-limiting and do not require significant intervention; others could cause significant morbidity or mortality. Physicians should begin with a thorough history and clinical examination to have the highest probability of making the correct diagnosis. Targeted questioning should focus on the type of trip taken, the travel itinerary, and a list of all geographic locations visited. Inquiries should also be m...
Source: American Family Physician - October 16, 2023 Category: Primary Care Authors: Nicholas A Rathjen S David Shahbodaghi Source Type: research
Antiviral activity of zinc against hepatitis viruses: current status and future prospects
This article provides a comprehensive overview of the findings on antiviral activity of zinc against hepatitis viruses, discusses the mechanisms underlying the antiviral properties of zinc and summarizes the prospects of harnessing the therapeutic benefit of zinc supplementation therapy in reducing the disease burden due to viral hepatitis. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - October 16, 2023 Category: Microbiology Source Type: research
Immune checkpoint inhibitor-induced neurotoxicity is not associated with seroprevalence of neurotropic infections
ConclusionPrevious viral, bacterial and protozoal neurotropic infections appear not to be associated with the development of neurological irAEs in melanoma patients who underwent therapy with ICI across 3 countries. Further efforts are needed to unravel the factors underlying neurological irAEs in order to identify risk factors for these toxicities, especially with the increasing use of ICI in earlier stage disease. (Source: Cancer Immunology, Immunotherapy)
Source: Cancer Immunology, Immunotherapy - October 14, 2023 Category: Cancer & Oncology Source Type: research
Local and systemic autoimmune manifestations linked to hepatitis A infection
Acta Gastroenterol Belg. 2023 Jul-Sep;86(3):429-436. doi: 10.51821/86.3.11299.ABSTRACTHepatitis A virus (HAV) represents a global burdening infectious agent causing in the majority of cases a self-limiting acute icteric syndrome, the outcome is related to the hepatic substrate and the potential pre-existing damage, whereas a plethora of extra-hepatic manifestations has also been reported. Despite the absence of post- HAV chronicity it has been associated with an additional burden on existing chronic liver diseases. Moreover, the induced immune response and the antigenic molecular mimicry are considered as triggering factor...
Source: Acta Gastro-Enterologica Belgica - October 10, 2023 Category: Gastroenterology Authors: M Doulberis A Papaefthymiou S A Polyzos E Vardaka M Tzitiridou-Chatzopoulou D Chatzopoulos A Koffas V Papadopoulos F Kyrailidi J Kountouras Source Type: research
