Global burden and trends of acute viral hepatitis among children and adolescents from 1990 to 2019: a systematic analysis of the Global Burden of Disease Study 2019
ConclusionEffective vaccines and treatments for hepatitis B and C offer eradication opportunities. Broadening diagnostic and therapeutic coverage is vital to address disparities in service provision for children and adolescents. (Source: Hepatology International)
Source: Hepatology International - March 26, 2024 Category: Infectious Diseases Source Type: research
Interleukin-2 enhancer binding factor 2 negatively regulates the replication of duck hepatitis A virus type 1 by disrupting the RNA-dependent RNA polymerase activity of 3D polymerase
AbstractThe interaction between viral components and cellular proteins plays a crucial role in viral replication. In a previous study, we showed that the 3 ′—untranslated region (3′—UTR) is an essential element for the replication of duck hepatitis A virus type 1 (DHAV-1). However, the underlying mechanism is still unclear. To gain a deeper understanding of this mechanism, we used an RNA pull-down and a matrix-assisted laser desorption/ionizati on time-of-flight mass spectrometry assay to identify new host factors that interact with the 3′—UTR. We selected interleukin-2 enhancer binding factor 2 (ILF2) for furt...
Source: Veterinary Research - March 26, 2024 Category: Veterinary Research Source Type: research
Concurrent Outbreaks of Hepatitis A, Invasive Meningococcal Disease, and Mpox, Florida, USA, 2021-2022
Emerg Infect Dis. 2024 Apr;30(4). doi: 10.3201/eid3004.231392.ABSTRACTIn 2022, concurrent outbreaks of hepatitis A, invasive meningococcal disease (IMD), and mpox were identified in Florida, USA, primarily among men who have sex with men. The hepatitis A outbreak (153 cases) was associated with hepatitis A virus genotype IA. The IMD outbreak (44 cases) was associated with Neisseria meningitidis serogroup C, sequence type 11, clonal complex 11. The mpox outbreak in Florida (2,845 cases) was part of a global epidemic. The hepatitis A and IMD outbreaks were concentrated in Central Florida and peaked during March--June, wherea...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Timothy J Doyle Megan Gumke Danielle Stanek Joshua Moore Brian Buck Timothy Locksmith Kelly Tomson Sarah Schmedes George Churchwell Shan Justin Hubsmith Baskar Krishnamoorthy Karalee Poschman Brandi Danforth Daniel Chacreton outbreak investigation team1 Source Type: research
Concurrent Outbreaks of Hepatitis A, Invasive Meningococcal Disease, and Mpox, Florida, USA, 2021-2022
Emerg Infect Dis. 2024 Apr;30(4). doi: 10.3201/eid3004.231392.ABSTRACTIn 2022, concurrent outbreaks of hepatitis A, invasive meningococcal disease (IMD), and mpox were identified in Florida, USA, primarily among men who have sex with men. The hepatitis A outbreak (153 cases) was associated with hepatitis A virus genotype IA. The IMD outbreak (44 cases) was associated with Neisseria meningitidis serogroup C, sequence type 11, clonal complex 11. The mpox outbreak in Florida (2,845 cases) was part of a global epidemic. The hepatitis A and IMD outbreaks were concentrated in Central Florida and peaked during March--June, wherea...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Timothy J Doyle Megan Gumke Danielle Stanek Joshua Moore Brian Buck Timothy Locksmith Kelly Tomson Sarah Schmedes George Churchwell Shan Justin Hubsmith Baskar Krishnamoorthy Karalee Poschman Brandi Danforth Daniel Chacreton outbreak investigation team1 Source Type: research
Concurrent Outbreaks of Hepatitis A, Invasive Meningococcal Disease, and Mpox, Florida, USA, 2021-2022
Emerg Infect Dis. 2024 Apr;30(4). doi: 10.3201/eid3004.231392.ABSTRACTIn 2022, concurrent outbreaks of hepatitis A, invasive meningococcal disease (IMD), and mpox were identified in Florida, USA, primarily among men who have sex with men. The hepatitis A outbreak (153 cases) was associated with hepatitis A virus genotype IA. The IMD outbreak (44 cases) was associated with Neisseria meningitidis serogroup C, sequence type 11, clonal complex 11. The mpox outbreak in Florida (2,845 cases) was part of a global epidemic. The hepatitis A and IMD outbreaks were concentrated in Central Florida and peaked during March--June, wherea...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Timothy J Doyle Megan Gumke Danielle Stanek Joshua Moore Brian Buck Timothy Locksmith Kelly Tomson Sarah Schmedes George Churchwell Shan Justin Hubsmith Baskar Krishnamoorthy Karalee Poschman Brandi Danforth Daniel Chacreton outbreak investigation team1 Source Type: research
Concurrent Outbreaks of Hepatitis A, Invasive Meningococcal Disease, and Mpox, Florida, USA, 2021-2022
Emerg Infect Dis. 2024 Apr;30(4). doi: 10.3201/eid3004.231392.ABSTRACTIn 2022, concurrent outbreaks of hepatitis A, invasive meningococcal disease (IMD), and mpox were identified in Florida, USA, primarily among men who have sex with men. The hepatitis A outbreak (153 cases) was associated with hepatitis A virus genotype IA. The IMD outbreak (44 cases) was associated with Neisseria meningitidis serogroup C, sequence type 11, clonal complex 11. The mpox outbreak in Florida (2,845 cases) was part of a global epidemic. The hepatitis A and IMD outbreaks were concentrated in Central Florida and peaked during March--June, wherea...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Timothy J Doyle Megan Gumke Danielle Stanek Joshua Moore Brian Buck Timothy Locksmith Kelly Tomson Sarah Schmedes George Churchwell Shan Justin Hubsmith Baskar Krishnamoorthy Karalee Poschman Brandi Danforth Daniel Chacreton outbreak investigation team1 Source Type: research
Concurrent Outbreaks of Hepatitis A, Invasive Meningococcal Disease, and Mpox, Florida, USA, 2021-2022
Emerg Infect Dis. 2024 Apr;30(4):633-43. doi: 10.3201/eid3004.231392.ABSTRACTIn 2022, concurrent outbreaks of hepatitis A, invasive meningococcal disease (IMD), and mpox were identified in Florida, USA, primarily among men who have sex with men. The hepatitis A outbreak (153 cases) was associated with hepatitis A virus genotype IA. The IMD outbreak (44 cases) was associated with Neisseria meningitidis serogroup C, sequence type 11, clonal complex 11. The mpox outbreak in Florida (2,845 cases) was part of a global epidemic. The hepatitis A and IMD outbreaks were concentrated in Central Florida and peaked during March--June,...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Timothy J Doyle Megan Gumke Danielle Stanek Joshua Moore Brian Buck Timothy Locksmith Kelly Tomson Sarah Schmedes George Churchwell Shan Justin Hubsmith Baskar Krishnamoorthy Karalee Poschman Brandi Danforth Daniel Chacreton outbreak investigation team1 Source Type: research
Concurrent Outbreaks of Hepatitis A, Invasive Meningococcal Disease, and Mpox, Florida, USA, 2021-2022
Emerg Infect Dis. 2024 Apr;30(4):633-43. doi: 10.3201/eid3004.231392.ABSTRACTIn 2022, concurrent outbreaks of hepatitis A, invasive meningococcal disease (IMD), and mpox were identified in Florida, USA, primarily among men who have sex with men. The hepatitis A outbreak (153 cases) was associated with hepatitis A virus genotype IA. The IMD outbreak (44 cases) was associated with Neisseria meningitidis serogroup C, sequence type 11, clonal complex 11. The mpox outbreak in Florida (2,845 cases) was part of a global epidemic. The hepatitis A and IMD outbreaks were concentrated in Central Florida and peaked during March--June,...
Source: Emerging Infectious Diseases - March 25, 2024 Category: Infectious Diseases Authors: Timothy J Doyle Megan Gumke Danielle Stanek Joshua Moore Brian Buck Timothy Locksmith Kelly Tomson Sarah Schmedes George Churchwell Shan Justin Hubsmith Baskar Krishnamoorthy Karalee Poschman Brandi Danforth Daniel Chacreton outbreak investigation team1 Source Type: research
