Pyogenic liver abscess as a late complication after embolization of a hepatic adenoma
Abstract Acute penile conditions, which typically have a traumatic, vascular, or infectious etiology, are rather uncommon and often require prompt medical evaluation. Penile emergencies can be treated conservatively or surgically, and their management often relies on the results of imaging examinations. Because of its high spatial resolution and wide availability, as well as the fact that it does not involve the use of ionizing radiation, ultrasound is the imaging modality of choice in the initial evaluation of penile emergencies. Inconclusive cases can be further evaluated with magnetic resonance imaging. The main purpose...
Source: Radiologia Brasileira - April 18, 2019 Category: Radiology Source Type: research

Hepatic disorders associated with exogenous sex steroids: MR imaging findings
AbstractObjectiveTo describe the MRI findings of the effects of exogenous sex steroids on the liver.FindingsEstrogens, progesterone and synthetic testosterone are exogenous sex steroids that may result in a variety of liver diseases, including tumour formation and vascular disorders. These hormones are mainly administered in the form of the oral contraceptive pill (OCP) and anabolic steroids. Both are implicated in hepatic adenoma formation. The HNF-1 α-mutated and inflammatory adenoma subgroups are more commonly seen in association with the OCP whereas there is an increased incidence of the β-catenin positive subtype wi...
Source: Abdominal Imaging - April 5, 2019 Category: Radiology Source Type: research

A case of hepatocellular carcinoma mimicking hepatic adenoma.
Authors: Goret CC, Goret NE, Ozkan OF Abstract Hepatocellular adenomas (HA) are benign naturally occurring masses that are rarely reported, and rarely reaching tumor size up to 30 cm. Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and usually caused by cirrhosis and more commonly reported tumors in males. It has been reported that presentations may occur with masses that are often less than 5 cm or rarely more than 10 cm. We aimed to present a case of hepatocellular carcinoma 72-years old man with fatigue and pain spread on the right upper quadrant; a histopathologic imag...
Source: Annali Italiani di Chirurgia - March 8, 2019 Category: Surgery Tags: Ann Ital Chir Source Type: research

Two-stage liver transplant for ruptured hepatic adenoma: A case report.
CONCLUSION: When toxic liver syndrome is recognized, liver transplantation with or without hepatectomy should be considered before the patient becomes unstable. PMID: 30820274 [PubMed] (Source: World Journal of Hepatology)
Source: World Journal of Hepatology - March 5, 2019 Category: Gastroenterology Tags: World J Hepatol Source Type: research

Hepatic adenoma during pregnancy and anesthetic management
Hepatic adenomas in pregnancy are described in the literature in small retrospective reviews, with 26 cases reported in pregnancy but none published in the anesthesia literature. Sixteen patients presented with hepatic rupture, frequently with a delay in diagnosis: maternal and fetal mortality were 44% and 38% respectively.[1] An aggressive approach, with hepatic resection of lesions greater than 5 cm, has been recommended.[2] In 2011, the multicenter prospective Pregnancy And Liver Adenoma Management (PALM) study was performed to generate diagnostic and management algorithms, the results of which are pending. (Source: Int...
Source: International Journal of Obstetric Anesthesia - January 11, 2019 Category: Anesthesiology Authors: J. Bernstein, Y. Spitzer, S. Reddy, A. Mazur Tags: Case report Source Type: research

Contrast-enhanced ultrasound in the diagnosis of pediatric focal nodular hyperplasia and hepatic adenoma: interobserver reliability
ConclusionThere is a good interobserver kappa for separating focal nodular hyperplasia from hepatic adenoma in children using established adult contrast-enhanced US features. (Source: Pediatric Radiology)
Source: Pediatric Radiology - January 1, 2019 Category: Radiology Source Type: research

Hepatobiliary and Pancreatic: Tumor to tumor metastasis from a primary insulinoma to a hepatic adenoma
Journal of Gastroenterology and Hepatology, EarlyView. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - September 7, 2018 Category: Gastroenterology Authors: XXu , LCong , YZhao Source Type: research

Benign Hepatic Lesions Arising in Accessory Hepatic Lobes
We report the histologic and immunohistochemical features of 3 cases of resected accessory hepatic lobes, all of which contained benign hepatic lesions (2 hepatic adenomas [HAs] and 1 focal nodular hyperplasia). All accessory lobes were connected to the liver by a pedicle. Histologically, all lesions demonstrated no cytologic or architectural atypia. Based on immunohistochemical analysis, 1 HA was classified as inflammatory type (positive for C-reactive protein and serum amyloid A), and 1 was unclassified type (negative for C-reactive protein, serum amyloid A, glutamine synthetase, and β-catenin and positive for liver fat...
Source: Pathology Case Reviews - August 29, 2018 Category: Pathology Tags: Review Source Type: research

Current Approaches in the Management of Hepatic Adenomas
ConclusionFuture genomic-based multicenter studies are required to provide a strong basis for formulating an evidence-based risk-adapted model that guides individualized management strategies for patients with HA. (Source: Journal of Gastrointestinal Surgery)
Source: Journal of Gastrointestinal Surgery - August 14, 2018 Category: Surgery Source Type: research

Long-term follow-up of hepatic adenoma and adenomatosis: analysis of size change on imaging with histopathological correlation
To analyse the change in size on follow-up of hepatic adenomas (HAs) and adenomatosis, and to investigate the relationship of imaging features with size change. (Source: Clinical Radiology)
Source: Clinical Radiology - July 18, 2018 Category: Radiology Authors: N. Shao, A. Pandey, M.A. Ghasabeh, P. Khoshpouri, P. Pandey, F.N. Varzaneh, M. Zarghampour, D. Fouladi, T.M. Pawlik, R.A. Anders, I.R. Kamel Source Type: research

False-positive 18F fluorodeoxyglucose positron emission tomography-avid benign hepatic tumor: Previously unreported in a male patient
We report a case of 18F fluorodeoxyglucose (FDG) positron emission tomography (PET)–computed tomography-avid histologically confirmed inflammatory hepatic adenoma in a 77-year-old male patient without any history of steroid, alcohol use. This is the first case report of inflammatory hepatic adenoma in a male patient documented in the published literature showing uptake on 18F-FDG PET. Previous single case report of 18F-FDG PET-avid hepatic adenoma in a male patient was of hepatocyte nuclear factor-1-α subtype. (Source: Indian Journal of Radiology and Imaging)
Source: Indian Journal of Radiology and Imaging - June 28, 2018 Category: Radiology Authors: Binit Sureka Archana Rastogi Amar Mukund Shiv Kumar Sarin Source Type: research

Triple-phase multidetector computed tomography:an evaluation of hepatic space occupying lesion in cirrhotic patients
Hepatocellular carcinoma (HCC) is a common tumor with an incidence of 1 - 6 % among cirrhotic patients. Dysplastic nodule often occurs within regenerative cirrhotic nodules. They can show low or high grade dysplasia. MRI best differentiates this iso-or hypo intense lesion from hyper intense HCC. The current study was designed to assess the usefulness of Triple-phase multiphasic multidetector computed tomography (MDCT) in evaluation of hepatic space occupying lesion in cirrhotic patients.This cross sectional study was carried out in Radiology and Imaging department in collaboration with Hepatology and Hepatobiliary surgery ...
Source: Bangladesh Medical Research Council Bulletin - June 6, 2018 Category: International Medicine & Public Health Source Type: research

Molecular Diagnostics in the Neoplasms of the Pancreas, Liver, Gallbladder, and Extrahepatic Biliary Tract
Pancreatic neoplasms, including ductal adenocarcinoma, solid pseudopapillary neoplasm, pancreatic endocrine neoplasms, acinar cell carcinoma, and pancreatoblastoma, are associated with different genetic abnormalities. Hepatic adenomas with beta-catenin exon 3 mutation are associated with a high risk of malignancy. Hepatic adenoma with arginosuccinate synthetase 1 expression or sonic hedgehog mutations are associated with a risk of bleeding. Hepatocellular carcinoma and choangiocarcinoma display heterogeneity at both morphologic and molecular levels Cholangiocellular carcinoma is most commonly associated with IDH 1/2 mutati...
Source: Clinics in Laboratory Medicine - May 16, 2018 Category: Laboratory Medicine Authors: Lei Zhang, Martin H. Bluth, Amarpreet Bhalla Source Type: research

Splenosis: a great mimicker of neoplastic disease
AbstractSplenosis is a benign condition that can occur after splenic trauma or after surgery involving the spleen. These splenic implants are most often seen within the abdominal and pelvic cavities. On imaging, splenosis can be confused with multiple additional entities including metastatic disease, peritoneal carcinomatosis, peritoneal mesothelioma, abdominal lymphoma, renal cancer, hepatic adenomas, or endometriosis depending on its distribution. In all patients with history of splenic surgery or trauma, splenosis should be on the differential diagnosis of soft tissue nodules in the abdomen and pelvis, especially in the...
Source: Abdominal Imaging - April 12, 2018 Category: Radiology Source Type: research

Clostridium paraputrificum septicemia and liver abscess.
We report the first case of a healthy 23-year-old female who underwent an interventional radiology-guided embolization of a hepatic adenoma, which resulted in a gas forming hepatic liver abscess and septicemia by Clostridium paraputrificum. A retrospective review of Clostridial liver abscesses was performed using a PubMed literature search, and we found 57 clostridial hepatic abscess cases. The two most commonly reported clostridial species are C. perfringens and C. septicum (64.9% and 17.5% respectively). C. perfringens cases carried a mortality of 67.6% with median survival of 11 h, and 70.2% of the C. perfringens cases ...
Source: World Journal of Hepatology - March 31, 2018 Category: Gastroenterology Tags: World J Hepatol Source Type: research