Clinico ‐pathological correlation of hepatic angiomyolipoma: a series of 23 resection cases
ConclusionsHepatic angiomyolipoma is a rare form of primary liver tumour and is often misdiagnosed as other hypervascular tumours. Although angiomyolipoma is benign in nature, it also has malignant potential; hence, resection is indicated if the tumour grows or malignancy cannot be excluded. Surgical resection is a definitive curative treatment of hepatic angiomyolipoma. (Source: ANZ Journal of Surgery)
Source: ANZ Journal of Surgery - January 24, 2017 Category: Surgery Authors: Dong Hwan Jung, Shin Hwang, Seung Mo Hong, Ki Hun Kim, Chul Soo Ahn, Deok Bog Moon, Abdulwahab A Alshahrani, Sung Gyu Lee Tags: Original Article Source Type: research
Hepatocellular adenoma: imaging review of the various molecular subtypes
This educational review focuses on the epidemiology and radiological evaluation of the various subtypes of hepatic adenomas (HCAs). It includes detailed discussion of the imaging appearances of each HCA subtype and the clinical relevance of the new classification system. Each HCA subtype has a unique biological behaviour. Imaging plays a central role in diagnosis, subtype characterisation, identification of complications, and follow-up assessment. Management of patients should vary according to the specific HCA subtype. (Source: Clinical Radiology)
Source: Clinical Radiology - January 22, 2017 Category: Radiology Authors: H. Dharmana, S. Saravana-Bawan, S. Girgis, G. Low Tags: Review Source Type: research
Identification of biomarkers of intrahepatic cholangiocarcinoma via integrated analysis of mRNA and miRNA microarray data.
Authors: Chen Y, Liu D, Liu P, Chen Y, Yu H, Zhang Q
Abstract
The present study aimed to identify potential therapeutic targets of intrahepatic cholangiocarcinoma (ICC) via integrated analysis of gene (transcript version) and microRNA (miRNA/miR) expression. The miRNA microarray dataset GSE32957 contained miRNA expression data from 16 ICC, 7 mixed type of combined hepatocellular‑cholangiocarcinoma (CHC), 2 hepatic adenoma, 3 focal nodular hyperplasia (FNH) and 5 healthy liver tissue samples, and 2 cholangiocarcinoma cell lines. In addition, the mRNA microarray dataset GSE32879 contained mRNA expression ...
Source: Molecular Medicine Reports - January 19, 2017 Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Hepatic adenomas in adolescents and young women with endometriosis treated with norethindrone acetate
Endometriosis —ectopic implantation of endometrial-like tissue—affects 10% of female adolescents and adults. First-line treatment includes progesterone-only (such as norethindrone acetate, NET-A) or combined estrogen/progestin oral contraceptive pills. Estrogen-containing contraceptives confer increased risk of hepatic adenomas, while the association with NET-A is very rarely reported. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - December 22, 2016 Category: OBGYN Authors: P.C. Brady, S.A. Missmer, M.R. Laufer Source Type: research
Complete spontaneous regression of giant focal nodular hyperplasia of the liver: Magnetic resonance imaging evaluation with hepatobiliary contrast media.
We present a patient with FNH of the liver who was followed up for 7 years. A 26-year-old woman with a 5-year history of oral contraceptive use was referred to our hospital in February 2005 for further examination of a liver tumour. The diagnosis of FNH was made using magnetic resonance (MR) imaging with hepatospecific contrast media; this technique allows a correct diagnosis, in particular distinguishing FNH from hepatic adenoma, avoiding an invasive procedure such as the lesion biopsy. After 7-year from the diagnosis, we observed the complete spontaneous regression of the lesion by enhanced MR scanning. In this patient, ...
Source: World Journal of Gastroenterology : WJG - December 20, 2016 Category: Gastroenterology Authors: Mamone G, Caruso S, Cortis K, Miraglia R Tags: World J Gastroenterol Source Type: research
Spontaneous rupture of hepatic metastasis from a thymoma: A case report.
Abstract
Bleeding resulting from spontaneous rupture of the liver is an infrequent but potentially life threatening complication that may be associated with an underlying liver disease. A hepatocellular carcinoma or hepatic adenoma is frequently reported is such cases. However, hemoperitoneum resulting from a hepatic metastatic thymoma is extremely rare. Here, we present a case of a 62-year-old man with hypovolemic shock induced by ruptured hepatic metastasis from a thymoma. At the first hospital admission, the patient had a 45-mm anterior mediastinal mass that was eventually diagnosed as a type A thymoma....
Source: World Journal of Gastroenterology : WJG - November 27, 2016 Category: Gastroenterology Authors: Kim HJ, Park YE, Ki MS, Lee SJ, Beom SH, Han DH, Park YN, Park JY Tags: World J Gastroenterol Source Type: research
Laparoscopic hepatectomy for segments I, IV, V and VIII
ConclusionLH for segments I, IV, V and VIII can be safely performed in selected patient in experienced center. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - November 6, 2016 Category: Surgery Source Type: research
Spontaneous Hepatic Hemorrhage: A Single Institution's 16-Year Experience.
We report our 16-year experience in managing spontaneous hemorrhage from liver tumors. Twenty-six consecutive patients were diagnosed with spontaneous liver hemorrhage between 1995 and 2011. Initial management was operative in eight, IR in six, and supportive in 12 patients. Of those managed operatively, five were segmentectomies; one hemihepatectomy; one wedge resection; and one packing who later died from coagulopathy. In the IR patients, seven had an angiographic embolization; two required reembolization; one underwent resection of a hepatic adenoma 21 days after angiographic embolization. The malignant lesions included...
Source: The American Surgeon - October 31, 2016 Category: Surgery Authors: Rosales A, Que FG Tags: Am Surg Source Type: research
Use of a Machine-learning Method for Predicting Highly Cited Articles Within General Radiology Journals
Conclusions Machine learning can be successfully applied to create specific feature-based models for predicting articles likely to achieve high influence within the radiological literature. (Source: Academic Radiology)
Source: Academic Radiology - September 27, 2016 Category: Radiology Source Type: research
Immunostains Used to Subtype Hepatic Adenomas Do Not Distinguish Hepatic Adenomas From Hepatocellular Carcinomas
Immunostains are used to subtype hepatic adenomas to stratify for the risk of malignant transformation. The most common panel of immunostains used for this purpose includes liver fatty acid–binding protein (LFABP), serum amyloid A (SAA) protein, C-reactive protein (CRP), and glutamine synthetase (GS). Importantly, some pathologists use these stains in an attempt to distinguish hepatocellular carcinomas (HCC) from hepatic adenomas. However, there are limited data on the performance of these stains in HCCs. To investigate the staining characteristics of HCCs, we studied 159 HCCs (92 well-differentiated, 67 moderately diffe...
Source: The American Journal of Surgical Pathology - July 13, 2016 Category: Pathology Tags: Original Articles Source Type: research
Validation of a Preclinical Model of Diethylnitrosamine-Induced Hepatic Neoplasia in Yucatan Miniature Pigs.
CONCLUSION: To our knowledge, we are the first to demonstrate an accelerated development of hepatic neoplasia in Yucatan miniature pigs. Our HCC swine model closely mimics the human condition (i.e., progressive disease stages and expression of relevant molecular markers) and is a viable translational model.
PMID: 27305144 [PubMed - as supplied by publisher] (Source: Oncology)
Source: Oncology - June 15, 2016 Category: Cancer & Oncology Authors: Mitchell J, Tinkey PT, Avritscher R, Van Pelt C, Eskandari G, Konnath George S, Xiao L, Cressman E, Morris JS, Rashid A, Kaseb AO, Amin HM, Uthamanthil R Tags: Oncology Source Type: research
Validation of a Preclinical Model of Diethylnitrosamine-Induced Hepatic Neoplasia in Yucatan Miniature Pigs
Conclusion: To our knowledge, we are the first to demonstrate an accelerated development of hepatic neoplasia in Yucatan miniature pigs. Our HCC swine model closely mimics the human condition (i.e., progressive disease stages and expression of relevant molecular markers) and is a viable translational model.Oncology (Source: Oncology)
Source: Oncology - June 15, 2016 Category: Cancer & Oncology Source Type: research
Reply to: "Indication of Percutaneous Microwave Ablation for the Treatment of Hepatic Adenomas: Squaring the Circle"
Publication date: June 2016 Source:Journal of Vascular and Interventional Radiology, Volume 27, Issue 6 Author(s): Maxime Ronot, Valérie Vilgrain (Source: Journal of Vascular and Interventional Radiology)
Source: Journal of Vascular and Interventional Radiology - June 6, 2016 Category: Radiology Source Type: research
Indication of Percutaneous Microwave Ablation for the Treatment of Hepatic Adenomas: Squaring the Circle
Publication date: June 2016 Source:Journal of Vascular and Interventional Radiology, Volume 27, Issue 6 Author(s): Maxime Ronot, Valérie Vilgrain (Source: Journal of Vascular and Interventional Radiology)
Source: Journal of Vascular and Interventional Radiology - June 2, 2016 Category: Radiology Source Type: research
Reply to: "Indication of Percutaneous Microwave Ablation for the Treatment of Hepatic Adenomas: Squaring the Circle"
We read with great interest the letter by Ronot and Vilgrain concerning our study of microwave ablation for the treatment of hepatocellular adenomas (HCAs) (1). The authors made several contentions that warrant closer scrutiny in an evolving era of management of patients with HCAs. (Source: Journal of Vascular and Interventional Radiology : JVIR)
Source: Journal of Vascular and Interventional Radiology : JVIR - May 31, 2016 Category: Radiology Authors: Timothy J Ziemlewicz, Amanda R. Smolock, Christopher L Brace Tags: Letter to the Editor Source Type: research
