Multicentre study on hepatic adenomas.
DISCUSSION: Patients with resected HA are normally women with large lesions and oestrogen consumption was lower than expected. Its correct preoperative diagnosis is acceptable (70%). The major hepatectomy rate is 25% and the laparoscopy rate is 20%. There was a low morbidity rate and no mortality. PMID: 23827931 [PubMed - as supplied by publisher] (Source: Cirugia eEspanola)
Source: Cirugia eEspanola - July 1, 2013 Category: Surgery Authors: Ramia JM, Bernardo C, Valdivieso A, Dopazo C, Jover JM, Albiol MT, Pardo F, Fernandez Aguilar JL, Gutierrez Calvo A, Serrablo A, Diez Valladares L, Pereira F, Sabater L, Muffak K, Figueras J Tags: Cir Esp Source Type: research

Radiofrequency ablation of a large hepatic adenoma in a child
We present a case of large hepatic adenoma successfully treated with RFA in a child with chronic liver disease secondary to alpha-1-antitrypsin deficiency. RFA may be an attractive option in pediatric liver tumor management in selected cases because of its less invasive characteristics. (Source: Journal of Pediatric Surgery)
Source: Journal of Pediatric Surgery - June 1, 2013 Category: Surgery Authors: Janice D. McDaniel, Kamlesh Kukreja, Ross L. Ristagno, Nada Yazigi, Jaimie D. Nathan, Gregory Tiao Tags: Journal of Pediatric Surgery Electronic Pages (Available only online at www.jpedsurg.org) Source Type: research

Two cases of hepatic adenomas in patients with wolf‐hirschhorn syndrome: A new rare complication?
We report on two patients with WHS patients in whom hepatic adenoma (HA) were diagnosed during adolescence. The clinical evolution of liver involvement was different between the two. We discuss the possibility of considering HA as a rare medical problem in the follow‐up of WHS patients. © 2013 Wiley Periodicals, Inc. (Source: American Journal of Medical Genetics Part A)
Source: American Journal of Medical Genetics Part A - May 21, 2013 Category: Genetics & Stem Cells Authors: Giulia Prunotto, Paola Cianci, Anna Cereda, Agnese Scatigno, Chiara Fossati, Silvia Maitz, Andrea Biondi, Angelo Selicorni Tags: Clinical Report Source Type: research

Current MR Imaging Lipid Detection Techniques for Diagnosis of Lesions in the Abdomen and Pelvis [Gastrointestinal Imaging]
This article reviews MR imaging fat detection techniques and discusses lesions in the abdomen and pelvis that can be readily diagnosed by using these techniques. Traditional fat detection methods include inversion-recovery and chemically selective fat-suppression pulse sequences, with the former being less sensitive to field heterogeneity and less tissue specific than the latter. Chemical shift–based sequences, which exploit the inherent resonance frequency difference between lipid and water to depict intracytoplasmic fat, have great utility for evaluating hepatic steatosis and lesions such as adrenal and hepatic ade...
Source: Radiographics recent issues - May 14, 2013 Category: Radiology Authors: Pokharel, S. S., Macura, K. J., Kamel, I. R., Zaheer, A. Tags: Magnetic Resonance Imaging, Gastrointestinal Radiology Gastrointestinal Imaging Source Type: research

Diagnostic Approach to Hepatic Mass Lesions and Role of Immunohistochemistry
Abstract: This review provides an overview of various hepatic mass lesions and a practical diagnostic approach, including most recent immunohistochemical stains used in clinical practice. A wide variety of benign and malignant lesions present as hepatic masses, and the differential diagnosis varies. In cirrhotic liver, the commonest malignant tumor is hepatocellular carcinoma (HCC), which needs to be differentiated from macroregenerative nodules, dysplastic nodules, and other tumors. The differential diagnosis of lesions in noncirrhotic liver in younger patients includes hepatic adenoma (HA), focal nodular hyperplasia (FNH...
Source: Surgical Pathology Clinics - May 7, 2013 Category: Pathology Authors: Esmeralda Celia Marginean, Allen M. Gown, Dhanpat Jain Source Type: research

High mobility group AT-hook 2 is overexpressed in hepatoblastoma
In conclusion, high mobility group AT-hook 2 is expressed in all hepatoblastomas and could be used as a sensitive marker in their diagnosis. High mobility group AT-hook 2 was also expressed in a subset of hepatocellular carcinomas in association with β-catenin expression; this might represent a subtype of hepatocellular carcinoma with hepatic progenitor cell differentiation. (Source: Human Pathology)
Source: Human Pathology - November 7, 2012 Category: Pathology Authors: Chung-Ta Lee, Lizhi Zhang, Taofic Mounajjed, Tsung-Teh Wu Tags: Original Contributions Source Type: research

Pigmented hepatocellular adenoma with complete CD34 immunostaining pattern: a diagnostic dilemma.
Abstract WHO defines hepatocellular adenoma (HCA) as a benign tumor composed of cells closely resembling normal hepatocytes, which are arranged in plates separated by sinusoids. It is more common in women. The present concerns a 41 years female who was found to have a mass lesion in liver on ultrasound while undergoing routine evaluation for dyspepsia. Computed tomography scan of abdomen showed 10×8 cm lesion in liver. Extended left hepatectomy was performed. Grossly hepatic cut surface showed circumscribed tumor with dark gray or black color. Microscopy revealed hepatocellular adenoma with abundant Dubin...
Source: Indian Journal of Pathology and Microbiology - October 1, 2012 Category: Pathology Authors: Vij M, Patra S, Rela M Tags: Indian J Pathol Microbiol Source Type: research