Comparison of Three Different Stents for EUS ‐guided Drainage of Pancreatic Fluid Collection: A Large Retrospective Study
ConclusionsThere are no significant differences in the clinical outcomes of PFC patients treated with PS, FCSEMS or LAMS. Nonetheless, severe (or even fatal) bleeding may occur at the early stage after metal stent placement, which should be paid particular attention to. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 26, 2018 Category: Gastroenterology Authors: Zhijie Wang, Shengbing Zhao, Qianqian Meng, Shuling Wang, Yan Chen, Fuming Wang, Qiang Li, Jun Yao, Yiqi Du, Zhendong Jin, Yu Bai, Zhaoshen Li, Dong Wang Tags: Biliary and Pancreatic Source Type: research

Ginsenoside Rb1 promotes intestinal epithelial wound healing through extracellular signal ‐regulated kinase and Rho signaling
ConclusionsDaikenchuto and its constituent, ginsenoside Rb1, promoted wound healing. Because mucosal healing is one of the most important therapeutic targets in patients with inflammatory bowel disease, ginsenoside Rb1 may be a novel therapeutic agent against intestinal mucosal damage such as that occurring in intestinal bowel disease. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: Yuki Toyokawa, Tomohisa Takagi, Kazuhiko Uchiyama, Katsura Mizushima, Ken Inoue, Chihiro Ushiroda, Saori Kashiwagi, Takahiro Nakano, Yuma Hotta, Makoto Tanaka, Osamu Dohi, Tetsuya Okayama, Naohisa Yoshida, Kazuhiro Katada, Kazuhiro Kamada, Tags: Gastroenterology Source Type: research

Clinical Practice of Chinese Medicine Navel Therapy for Chronic Diarrhea: A Literature Review
ConclusionsThe application of Chinese medicine navel therapy could be one of the ideal treatments for chronic diarrhea in the future, especially for children. However, high ‐quality studies are very needed to provide clear evidence. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: Meng ‐rui Chen, Jiang Zhao, Shu‐fei Fu, Jia‐qi Yu, Xuan Zhang, Qi‐yang Zhang, Zhi‐huan Zhou Tags: Review Source Type: research

Lactulose Hydrogen Breath Test with Test Meal allows discrimination between Functional Gastrointestinal Disorder and Healthy Volunteer
ConclusionsIn this study we demonstrated significant differences in postprandial symptom generation in FD and IBS compared to HV after LHBT. This does not only allow us to discriminate FD/IBS from HV but may also represent a diagnostic and monitoring tool for FD/IBS in the future, including monitoring of treatment effects. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: Valeria Schindler, St éphanie Giezendanner, Simon Bütikofer, Fritz Murray, Daniel Runggaldier, Larissa Schnurre, Annina Zweig, Michael Fried, Daniel Pohl Tags: Gastroenterology Source Type: research

Incidence and clinical impact of perianal disease in patients with ulcerative colitis: A nationwide population ‐based study
ConclusionsThe risk of PAD is higher in UC patients than in the general population. UC patients with PAD have distinct clinical features and poor outcomes, as indicated by the greater need for UC ‐related medications and colectomy. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: Eun Mi Song, Ho ‐Su Lee, Ye‐Jee Kim, Eun Hye Oh, Nam Seok Ham, Jeongseok Kim, Sung Wook Hwang, Sang Hyoung Park, Dong‐Hoon Yang, Byong Duk Ye, Jeong‐Sik Byeon, Seung‐Jae Myung, Suk‐Kyun Yang Tags: Gastroenterology Source Type: research

Risk of skin cancers in thiopurines ‐treated and thiopurines‐untreated patients with inflammatory bowel disease: A systematic review and meta‐analysis
AbstractBackground and AimThe thiopurines are effective in the management of patients with inflammatory bowel disease (IBD), but the association between thiopurines use and the risk of skin cancer (including nonmelanoma skin cancer [NMSC] and melanoma skin cancer) has already been sufficiently reported. However, the results of these studies are inconsistent, and thus, the objective of our analysis was to explore whether thiopurines can lead to an excess risk of skin cancer in IBD patients.MethodsMEDLINE, EMBASE, and the Cochrane Library were searched to identify relevant studies that evaluated the risk of skin cancer in IB...
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: Shao ‐Zhuo Huang, Zhi‐Cheng Liu, Wei‐Xin Liao, Jun‐Xiao Wei, Xiao‐Wen Huang, Chen Yang, Yu‐Han Xia, Lu Li, Chao Ye, Shi‐Xue Dai Tags: Meta Analysis and Systematic Review Source Type: research

Hepatobiliary and Pancreatic: Pyoderma gangrenosum of the pancreas successfully treated with infliximab
Journal of Gastroenterology and Hepatology, EarlyView. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: N Deprez, F Dedeurwaerdere, L Desomer, D De Wulf Tags: Education and Imaging Source Type: research

Unique patterns of glycosylation in immunoglobulin subclass G4 ‐related disease and primary sclerosing cholangitis
AbstractBackground and AimImmunoglobulin subclass G4 ‐related disease (IgG4‐RD) is characterized by an abundance of IgG4 antibodies in the serum and tissue. Glycosylation status of antibodies can impact on immune effector functions and disease pathophysiology. We sought to establish glycosylation patterns in a prospective cohort of patients with I gG4‐RD and the relationship with disease activity and response to treatment.MethodsWe assessed IgG Fc ‐tail and Fab‐arm glycosylation status in patients with IgG4‐RD (n = 22), disease controls with primary sclerosing cholangitis (PSC) (n = 22), and...
Source: Journal of Gastroenterology and Hepatology - November 22, 2018 Category: Gastroenterology Authors: Emma L Culver, Fleur S Bovenkamp, Ninotska I L Derksen, Jana Koers, Tamsin Cargill, Eleanor Barnes, Louise A Neef, Carolien A M Koeleman, Rob C Aalberse, Manfred Wuhrer, Theo Rispens Tags: Biliary and Pancreatic Source Type: research

Clinical validation of the ‘7x7’ questionnaire for patients with functional gastrointestinal disorders
Conclusionsthe ‘7x7’ questionnaire is a convenient, sensitive, and reliable tool for assessing the severity of symptoms and treatment efficacy in people with functional gastrointestinal disorders. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 21, 2018 Category: Gastroenterology Authors: Vladimir Ivashkin, Arkady Sheptulin, Oleg Shifrin, Elena Poluektova, Chavdar Pavlov, Konstantin Ivashkin, Alexandra Drozdova, Olga Lyashenko, Alexandr Korolev Tags: Gastroenterology Source Type: research

Clinical and pathological features of combined hepatocellular ‐cholangiocarcinoma compared with other liver cancers
This study aimed to clarify these aspects of CHC .Methods: We enrolled 28 patients with CHC, 1050 with HCC, and 100 with ICC and compared the clinicopathological characteristics and prognosis of CHC with HCC and ICC. We also analyzed prognostic factors, recurrence patterns, and management in CHC patients.ResultsThe incidences of hepatitis B virus (HBV), and high alpha ‐fetoprotein (AFP) and protein induced by vitamin K absence or antagonists‐II (PIVKAII) levels were significantly higher among CHC compared with ICC patients. Multiple tumors were more frequent in CHC compared with the other groups, while vascular invasio...
Source: Journal of Gastroenterology and Hepatology - November 21, 2018 Category: Gastroenterology Authors: Kazuki Wakizaka, Hideki Yokoo, Toshiya Kamiyama, Masafumi Ohira, Koichi Kato, Yuki Fujii, Ko Sugiyama, Naoki Okada, Takanori Ohata, Akihisa Nagatsu, Shingo Shimada, Tatsuya Orimo, Hirofumi Kamachi, Akinobu Taketomi Tags: Hepatology Source Type: research

Analysis of risk factors and development of scoring system to predict severity of upper gastrointestinal bleeding in children
AbstractBackground and AimUpper gastrointestinal bleeding is a rare and potentially life ‐threatening condition in children. Herein, clinical features and risk factors in children with upper gastrointestinal bleeding were analyzed and a clinical scoring system was constructed to assess severity.MethodsThis retrospective cohort study involved 224 children hospitalized with upper gastrointestinal bleeding between January 2012 and April 2018. Demographic data, clinical information and laboratory test results on admission were statistically examined.ResultsOut of 224 upper gastrointestinal bleeding cases, 76 were diagnosed a...
Source: Journal of Gastroenterology and Hepatology - November 21, 2018 Category: Gastroenterology Authors: Wei Zheng, Linmei Jiang, Xinyi Jia, Gao Long, Xiaoli Shu, Mizu Jiang Tags: Gastroenterology Source Type: research

Clinical Features of Idiopathic Portal Hypertension in China: A Retrospective Study of 338 Patients and Literature Review
ConclusionsHigh ‐quality liver biopsy, detailed clinical information, and expert pathologist are necessary for diagnosis of IPH. IPH can occur concurrently with other liver disease such as hepatitis and drug‐induced liver injury. Medication appears to be an important etiological factor for IPH in China. Managem ent approach was largely focused on treatment of portal hypertension and its complications. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 21, 2018 Category: Gastroenterology Authors: Yongliang Sun, Xu Lan, Chen Shao, Tailing Wang, Zhiying Yang Tags: Hepatology Source Type: research

Impact of family history of colorectal cancer on age ‐specific prevalence of colorectal neoplasia
ConclusionAlthough a family history of CRC is a risk factor for NAA, it may affect NAA development from the mid ‐50s and ACRN development from the early 60s. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 21, 2018 Category: Gastroenterology Authors: Chan Hyuk Park, Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Yoon Suk Jung Tags: Gastroenterology Source Type: research

Cost ‐effectiveness of sofosbuvir plus ribavirin therapy for hepatitis C virus genotype 2 infection in South Korea
ConclusionsThe SOF+RBV is a cost ‐effective option for genotype 2 treatment‐naïve CHC patients, especially for the patients with liver cirrhosis in Korea. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 21, 2018 Category: Gastroenterology Authors: Wankyo Chung, Kyung ‐Ah Kim, Eun Sun Jang, Moran Ki, Hwa Young Choi, Sook‐Hyang Jeong Tags: Hepatology Source Type: research

Natural history of gastrointestinal manifestations in vascular Ehlers –Danlos syndrome: A 17‐year retrospective review
ConclusionsVascular Ehlers –Danlos syndrome is characterized not only by bowel perforation but also by a wide variety of GI complications that occur in close to half (41%) of patients. The pattern of GI fragility seems more severe in males and splice‐site variants. Complications of GI surgery are common and are related wi th tissue fragility/friability. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 20, 2018 Category: Gastroenterology Authors: Michael Frank, Salma Adham, Franck Zinzindohou é, Xavier Jeunemaitre Tags: Gastroenterology Source Type: research

Gastrointestinal: An oral clue to an unusual cause of pain abdomen: Burton's line
Journal of Gastroenterology and Hepatology, EarlyView. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 18, 2018 Category: Gastroenterology Authors: S Verma, AP Santhosh, S Shukla, P Gupta, HS Mandavdhare, U Dutta, V Sharma Tags: Education and Imaging Source Type: research

Emerging trends of inflammatory bowel disease in South Korea: a nationwide population ‐based study
AbstractBackground and AimsLittle is known regarding the exact burden of inflammatory bowel disease (IBD) in Asian countries because previous epidemiologic studies were hospital ‐based. We aimed to develop and validate an operational definition of IBD cases from health insurance claims data and to examine the epidemiological features of IBD in Korea.MethodsWe analyzed stratified sample data from the Korean Health Insurance Review and Assessment (2010 –2016) database using 12 different definitions and applied the best definition to the entire (2007–2016) dataset.ResultsThe definition that combined the ICD ‐1...
Source: Journal of Gastroenterology and Hepatology - November 16, 2018 Category: Gastroenterology Authors: Min Seob Kwak, Jae Myung Cha, Hun Hee Lee, Yong Sung Choi, Seung In Seo, Kyung Jin Ko, Dong Il Park, Sung Hun Kim, Tae Jun Kim Tags: Gastroenterology Source Type: research

Issue Information
No abstract is available for this article. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Issue Information Source Type: research

Author Index
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 566-588, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Author Index Source Type: research

APDW 2018 E ‐poster Exhibitions – Pancreas
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 532-545, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

APDW 2018 E ‐poster Exhibitions – Lower GI
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 447-531, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

APDW 2018 E ‐poster Exhibitions – Liver
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 394-446, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

APDW 2018 E ‐poster Exhibitions – Gastric and Duodenal
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 337-393, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

APDW 2018 E ‐poster Exhibitions – Esophagus
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 318-336, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

APDW 2018 E ‐poster Exhibitions – Endoscopy
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 240-317, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

APDW 2018 E ‐poster Exhibitions – Biliary
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 222-239, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

APDW 2018 E ‐poster Presentations
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 54-221, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

APDWF Posters of Distinction Awards Presentations
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 43-53, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

List of Contents
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 6-30, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

APDW 2018 E ‐poster Exhibitions – Surgery
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 557-565, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

APDW 2018 E ‐poster Exhibitions – Small Intestine
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 549-556, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

APDW 2018 Plenary Oral Presentations
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 31-39, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

APDWF/JGHF Young Investigator's Awards Presentations
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 40-42, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

APDW 2018 E ‐poster Exhibitions – Pediatric
Journal of Gastroenterology and Hepatology, Volume 33, Issue S4, Page 546-548, November 2018. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Tags: Supplement Article Source Type: research

Hepatobiliary and Pancreatic: Glycogenic hepatopathy in a patient with poorly controlled diabetes mellitus mimics a hepatic neoplasm
Journal of Gastroenterology and Hepatology, EarlyView. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 15, 2018 Category: Gastroenterology Authors: Z ‐y Chen, Y‐p Liu, D‐j Zhou Tags: Education and Imaging Source Type: research

Circulating tumor cells detected using fluid ‐assisted separation technique in esophageal squamous cell carcinoma
AbstractBackground and AimsEsophageal squamous cell carcinoma (ESCC) is one of the aggressive gastrointestinal tract cancers. Detection of circulating tumor cells (CTCs) in peripheral blood from patients with various malignancies has been reported to have diagnostic, prognostic, and therapeutic implications. We aimed to evaluate CTCs in patients with ESCC and assess the clinical significance of CTCs in the early diagnosis of ESCC.MethodsPeripheral blood samples for CTCs analyses were prospectively obtained from 73 patients with ESCC prior to treatment between March 2015 and June 2018. CTCs were detected using a centrifugal...
Source: Journal of Gastroenterology and Hepatology - November 13, 2018 Category: Gastroenterology Authors: Mun Ki Choi, Gwang Ha Kim, Hoseok I, Su Jin Park, Moon Won Lee, Bong Eun Lee, Do Youn Park, Yoon ‐Kyoung Cho Tags: Gastroenterology Source Type: research

Comparison of Endoscopic Ultrasound Tissue Acquisition Methods for Genomic Analysis of Pancreatic Cancer
AbstractBackground and AimTumor genotyping may allow for improved prognostication and targeted therapy for pancreatic adenocarcinoma (PDAC). We aimed to compare endoscopic ultrasonography (EUS) with fine needle aspiration (FNA) to fine needle biopsy (FNB) for obtaining sufficient tissue for genomic analysis and theranostic potential.MethodsA retrospective cohort study of patients undergoing EUS ‐FNA and EUS‐FNB with either positive or suspicious cytology for PDAC between March 2016 and December 2017. Demographic, procedural, and cytology data were recorded. Genetic alterations were recorded and Kaplan‐Meier survival ...
Source: Journal of Gastroenterology and Hepatology - November 13, 2018 Category: Gastroenterology Authors: Sherif Elhanafi, Nadim Mahmud, Norge Vergara, Michael L Kochman, Koushik K Das, Gregory G Ginsberg, Michael Rajala, Vinay Chandrasekhara Tags: Endoscopy Source Type: research

Serrated Protein Acidic And Rich In Cysteine (SPARC) Gene Variants: Impact On Susceptibility & Survival Of HCC Patients
AbstractBackgroundSecreted protein acidic and rich in cysteine (SPARC) is a glycoprotein involved in extracellular matrix (ECM) remodeling which regulates cell growth. It could be involved in hepatic fibrogenesis related to chronic inflammations, hepatocellular carcinoma (HCC) angiogenesis, and tumor progression.AimWe aimed to study the expressions of single nucleotide polymorphisms (SNPs) in the SPARC gene and their impact on susceptibility and survival of HCC patients.Patients and methods: We conducted a case ‐control study on 200 HCC patients and 50‐matched healthy controls. All patients were subjected to laboratory...
Source: Journal of Gastroenterology and Hepatology - November 13, 2018 Category: Gastroenterology Authors: Samar Kamal Darweesh, Rasha Ahmed Abd Alziz, Heba Omar, Dina Sabry, Wael Fathy Tags: Hepatology Source Type: research

Hepatobiliary and Pancreatic: Sclerosing extramedullary hematopoietic tumor involving hepatic hilum
Journal of Gastroenterology and Hepatology, EarlyView. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 12, 2018 Category: Gastroenterology Authors: G Can Sezgin, K Deniz, Öİ Karahan, Ş Gürsoy Tags: Education and Imaging Source Type: research

Significance of hypovascular lesions on dynamic computed tomography and/or gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid ‐enhanced magnetic resonance imaging in patients with hepatocellular carcinoma
ConclusionsIt remains uncertain whether these hypovascular lesions should be resected together with the main tumors at the time of hepatectomy. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 9, 2018 Category: Gastroenterology Authors: Yu Gyoda, Hiroshi Imamura, Hirofumi Ichida, Jiro Yoshimoto, Yoichi Ishizaki, Ryohei Kuwatsuru, Seiji Kawasaki Tags: Hepatology Source Type: research

Helicobacter pylori increases the risk of low ‐dose aspirin ulcers: A meta‐analysis
ConclusionThis analysis suggestsHelicobacter pylori increases the risk of LDA ulcers by almost 70% in a population where some were taking proton pump inhibitors and/or other acid suppressants. Without antisecretory drugs, the risk almost doubles. Clinically, these findings may support the use of a test ‐and‐treat approach toHelicobacter pylori in LDA users, particularly those at higher risk of developing for peptic ulcers. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 8, 2018 Category: Gastroenterology Authors: Gino L Sarri, Sam E Grigg, Neville D Yeomans Tags: Meta Analysis and Systematic Review Source Type: research

Declining in liver stiffness cannot indicate fibrosis regression in patients with chronic hepatitis B: A 78 ‐week prospective study
ConclusionsIn CHB patients receiving 78 ‐week antiviral treatment, LSM could diagnosis different liver fibrosis stages, decrease in absolute LSM value could reflect the remission of liver inflammation, and baseline Ishak fibrosis score was the only predictor for 78‐week fibrosis reversion. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 8, 2018 Category: Gastroenterology Authors: Xiao ‐Qin Dong, Zhao Wu, Jun Li, Gui‐Qiang Wang, Hong Zhao, China HepB‐Related Fibrosis Assessment Research Group Tags: Hepatology Source Type: research

Thrombocytopenia: a prognostic factor for hepatocellular carcinoma patients with portal vein tumor thrombus after hepatectomy
This study aimed to evaluate the value of PLT counts in the prognosis of HCC patients with PVTT after hepatectomy.MethodsFrom January 2002 to December 2012, 694 HCC patients with PVTT after hepatectomy were evaluated. The patients were divided into the thrombocytopenia group (PLT 300 ×10^9/L) based on the preoperative PLT level. A propensity score matching (PSM) analysis was used.ResultsBefore the PSM, PVTT patients with thrombocytopenia exhibited longer recurrence ‐free survival (RFS) and overall survival (OS) compared to those with normal PLT counts (both p
Source: Journal of Gastroenterology and Hepatology - November 7, 2018 Category: Gastroenterology Authors: Yu ‐Qiang Cheng, Kang Wang, Xiu‐Ping Zhang, Xu‐Biao Wei, Ya‐Bo Jiang, Yi‐Ren Hu, Fei‐Fei Mao, Wei‐Xing Guo, Jie Shi, Shu‐Qun Cheng Tags: Hepatology Source Type: research

Effects of In ‐Hospital Exercise on Sarcopenia in Hepatoma Patients Who Underwent Transcatheter Arterial Chemoembolization
ConclusionsIn ‐hospital exercises increased muscle mass in HCC patients who underwent TACE. In addition, exercise was an independent factor for muscle hypertrophy. Thus, in‐hospital exercise may prevent sarcopenia in HCC patients who underwent TACE. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 7, 2018 Category: Gastroenterology Authors: Shunji Koya, Takumi Kawaguchi, Ryuki Hashida, Keisuke Hirota, Masafumi Bekki, Emiko Goto, Maiko Yamada, Masako Sugimoto, Saki Hayashi, Norihiro Goshima, Teruhito Yoshiyama, Takashi Otsuka, Ryosuke Nozoe, Ayu Nagamatsu, Dan Nakano, Tomotake Tags: Hepatology Source Type: research

Okuda Lecture: Challenges of Hepatitis B in the Era of Antiviral Therapy
AbstractNucleos(t) ide analogues (NA) are effective, safe, and convenient antiviral therapy to suppress replication of hepatitis B virus (HBV), which can be translated into improved long ‐term outcome of chronic hepatitis B patients. The current recommended first‐line NA, namely entecavir and tenofovir, are largely free from problems of drug resistance. Nonetheless, there are still a few challenges in the era of NA. First, the risk of hepatocellular carcinoma (HCC) can only be r educed but not eliminated, particularly among cirrhotic patients. For cirrhotic patients who have persistent low level viremia on NA, i.e. par...
Source: Journal of Gastroenterology and Hepatology - November 6, 2018 Category: Gastroenterology Authors: Henry Lik Yuen Chan Tags: Solicited Review Source Type: research

Monitoring serum proangiogenic cytokines from hepatocellular carcinoma patients treated with sorafenib
Conclusions: Predictions of overall survival and post ‐progression survival were possible by periodically measuring serum proangiogenic cytokines, especially angiopoietin‐2, in patients with HCC treated with sorafenib. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 6, 2018 Category: Gastroenterology Authors: Takuya Adachi, Kazuhiro Nouso, Koji Miyahara, Atsushi Oyama, Nozomu Wada, Chihiro Dohi, Yasuto Takeuchi, Tetsuya Yasunaka, Hideki Onishi, Fusao Ikeda, Shinichiro Nakamura, Hidenori Shiraha, Akinobu Takaki, Hiroyuki Takabatake, Shin ‐ichi F Tags: Hepatology Source Type: research

Reduction in butyrate ‐producing Lachnospiraceae contributes to stress‐induced visceral hypersensitivity in rats
Conclusions: Reduction in the abundance of butyrate ‐producing Lachnospiraceae, which is beneficial for the intestinal barrier, was involved in the formation of visceral hypersensitivity.R. hominis is a potential probiotic for treating stress ‐induced visceral hypersensitivity. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 6, 2018 Category: Gastroenterology Authors: Jindong Zhang, Lijin Song, Yujing Wang, Chang Liu, Lu Zhang, Shiwei Zhu, Shuangjiang Liu, Liping Duan Tags: Gastroenterology Source Type: research

Identification of genes with universally up ‐ or down‐regulated expressions in colorectal cancer
Journal of Gastroenterology and Hepatology,Volume 0, Issue ja, -Not available-. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 5, 2018 Category: Gastroenterology Authors: Kai Song, Wei Su, Yanlong Liu, Jiahui Zhang, Qirui Liang, Na Li, Qingzhou Guan, Jun He, Xuefeng Bai, Wenyuan Zhao, Zheng Guo Source Type: research

The relationship between a cirrhosis ‐specific comorbidity scoring system and healthcare utilization patterns
Journal of Gastroenterology and Hepatology,Volume 0, Issue ja, -Not available-. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 5, 2018 Category: Gastroenterology Authors: Ankur A Dashputre, Branden D Nemecek, Khalid M Kamal, Jordan R Covvey Source Type: research

Ginsenoside Rb1 promotes intestinal epithelial wound healing through ERK and Rho signaling
Journal of Gastroenterology and Hepatology,Volume 0, Issue ja, -Not available-. (Source: Journal of Gastroenterology and Hepatology)
Source: Journal of Gastroenterology and Hepatology - November 5, 2018 Category: Gastroenterology Authors: Yuki Toyokawa, Tomohisa Takagi, Kazuhiko Uchiyama, Katsura Mizushima, Ken Inoue, Chihiro Ushiroda, Saori Kashiwagi, Takahiro Nakano, Yuma Hotta, Makoto Tanaka, Osamu Dohi, Tetsuya Okayama, Naohisa Yoshida, Kazuhiro Katada, Kazuhiro Kamada, Source Type: research