Remodeling of Gut Microbiota by Probiotics Alleviated Heat Stroke ‐Induced Necroptosis in Male Germ Cells
ConclusionProbiotics-based remodeling of gut microbiota (GM) reduces the proliferation of abnormal bacteria and decreases the spread of gut-derived inflammatory mediators into the blood circulation under long-term systemic heat stress, which relieves inflammation on germ cells. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - July 17, 2023 Category: Food Science Authors: Hui Cai,
Dezhe Qin,
Yundie Liu,
Xinrui Guo,
Yang Liu,
Baohua Ma,
Jinlian Hua,
Sha Peng Tags: Research Article Source Type: research
Remodeling of Gut Microbiota by Probiotics Alleviated Heat Stroke-Induced Necroptosis in Male Germ Cells
CONCLUSION: Probiotics-based remodeling of gut microbiota (GM) reduces the proliferation of abnormal bacteria and decreases the spread of gut-derived inflammatory mediators into the blood circulation under long-term systemic heat stress, which relieves inflammation on germ cells.PMID:37454346 | DOI:10.1002/mnfr.202300291 (Source: Cell Research)
Source: Cell Research - July 16, 2023 Category: Cytology Authors: Hui Cai Dezhe Qin Yundie Liu Xinrui Guo Yang Liu Baohua Ma Jinlian Hua Sha Peng Source Type: research
Calcitonin gene-related peptide inhibits neuronal apoptosis in heatstroke rats via PKA/p-CREB pathway
CONCLUSIONS: CGRP can protect against HS-induced neuron apoptosis via PKA/p-CREB pathway and reduce activation of caspase-3 by regulating Bcl-2. Thus CGRP may be a new target for the treatment of brain injury in HS.PMID:37423838 | DOI:10.1016/j.cjtee.2023.06.002 (Source: Chinese Journal of Traumatology)
Source: Chinese Journal of Traumatology - July 9, 2023 Category: Orthopaedics Authors: Jie Zhu Ya-Hong Chen Jing-Jing Ji Cheng-Xiang Lu Zhi-Feng Liu Source Type: research
Calcitonin gene-related peptide inhibits neuronal apoptosis in heatstroke rats via PKA/p-CREB pathway
CONCLUSIONS: CGRP can protect against HS-induced neuron apoptosis via PKA/p-CREB pathway and reduce activation of caspase-3 by regulating Bcl-2. Thus CGRP may be a new target for the treatment of brain injury in HS.PMID:37423838 | DOI:10.1016/j.cjtee.2023.06.002 (Source: Chinese Journal of Traumatology)
Source: Chinese Journal of Traumatology - July 9, 2023 Category: Orthopaedics Authors: Jie Zhu Ya-Hong Chen Jing-Jing Ji Cheng-Xiang Lu Zhi-Feng Liu Source Type: research
Calcitonin gene-related peptide inhibits neuronal apoptosis in heatstroke rats via PKA/p-CREB pathway
CONCLUSIONS: CGRP can protect against HS-induced neuron apoptosis via PKA/p-CREB pathway and reduce activation of caspase-3 by regulating Bcl-2. Thus CGRP may be a new target for the treatment of brain injury in HS.PMID:37423838 | DOI:10.1016/j.cjtee.2023.06.002 (Source: Chinese Journal of Traumatology)
Source: Chinese Journal of Traumatology - July 9, 2023 Category: Orthopaedics Authors: Jie Zhu Ya-Hong Chen Jing-Jing Ji Cheng-Xiang Lu Zhi-Feng Liu Source Type: research
Calcitonin gene-related peptide inhibits neuronal apoptosis in heatstroke rats via PKA/p-CREB pathway
CONCLUSIONS: CGRP can protect against HS-induced neuron apoptosis via PKA/p-CREB pathway and reduce activation of caspase-3 by regulating Bcl-2. Thus CGRP may be a new target for the treatment of brain injury in HS.PMID:37423838 | DOI:10.1016/j.cjtee.2023.06.002 (Source: Chinese Journal of Traumatology)
Source: Chinese Journal of Traumatology - July 9, 2023 Category: Orthopaedics Authors: Jie Zhu Ya-Hong Chen Jing-Jing Ji Cheng-Xiang Lu Zhi-Feng Liu Source Type: research
Calcitonin gene-related peptide inhibits neuronal apoptosis in heatstroke rats via PKA/p-CREB pathway
CONCLUSIONS: CGRP can protect against HS-induced neuron apoptosis via PKA/p-CREB pathway and reduce activation of caspase-3 by regulating Bcl-2. Thus CGRP may be a new target for the treatment of brain injury in HS.PMID:37423838 | DOI:10.1016/j.cjtee.2023.06.002 (Source: Chinese Journal of Traumatology)
Source: Chinese Journal of Traumatology - July 9, 2023 Category: Orthopaedics Authors: Jie Zhu Ya-Hong Chen Jing-Jing Ji Cheng-Xiang Lu Zhi-Feng Liu Source Type: research
Calcitonin gene-related peptide inhibits neuronal apoptosis in heatstroke rats via PKA/p-CREB pathway
CONCLUSIONS: CGRP can protect against HS-induced neuron apoptosis via PKA/p-CREB pathway and reduce activation of caspase-3 by regulating Bcl-2. Thus CGRP may be a new target for the treatment of brain injury in HS.PMID:37423838 | DOI:10.1016/j.cjtee.2023.06.002 (Source: Chinese Journal of Traumatology)
Source: Chinese Journal of Traumatology - July 9, 2023 Category: Orthopaedics Authors: Jie Zhu Ya-Hong Chen Jing-Jing Ji Cheng-Xiang Lu Zhi-Feng Liu Source Type: research
Heat stress-induced intestinal epithelial cells necroptosis via TLR3-TRIF-RIP3 pathway was dependent on p53
CONCLUSION: Heat stress promoted p53 phosphorylation, then upregulated TLR3 and enhanced the interaction of TRIF-RIP3, which would activate the RIP3-MLKL signaling pathway to mediate necroptosis in intestinal epithelial cells.PMID:37421775 | DOI:10.1016/j.intimp.2023.110574 (Source: International Immunopharmacology)
Source: International Immunopharmacology - July 8, 2023 Category: Allergy & Immunology Authors: Junjie Zhou Xihe Qin Li Li Dan Tian Zhimin Zou Zhengtao Gu Lei Su Source Type: research
Heat stress-induced intestinal epithelial cells necroptosis via TLR3-TRIF-RIP3 pathway was dependent on p53
CONCLUSION: Heat stress promoted p53 phosphorylation, then upregulated TLR3 and enhanced the interaction of TRIF-RIP3, which would activate the RIP3-MLKL signaling pathway to mediate necroptosis in intestinal epithelial cells.PMID:37421775 | DOI:10.1016/j.intimp.2023.110574 (Source: International Immunopharmacology)
Source: International Immunopharmacology - July 8, 2023 Category: Allergy & Immunology Authors: Junjie Zhou Xihe Qin Li Li Dan Tian Zhimin Zou Zhengtao Gu Lei Su Source Type: research
Glasgow Coma Scale as an Indicator of Patient Prognosis: A Retrospective Study of 257 Patients with Heatstroke from 3 Medical Centers in Guangdong, China
CONCLUSIONS GCS ≤8 at admission predicted worse outcomes in heatstroke patients, which possibly enhanced the risks of death for other factors, including age, RR, and HCT.PMID:37357421 | DOI:10.12659/MSM.939118 (Source: Medical Science Monitor)
Source: Medical Science Monitor - June 26, 2023 Category: Research Authors: HuaiSheng Chen Ronglin Chen Xinghui Wu Jing Qian Xuezhi Shi Lulu Wan Wang Fanfan Huasheng Tong Source Type: research
US caregivers' attitudes and risk perceptions towards pediatric vehicular heatstroke: A national survey
The objective of this study was to characterize caregivers' beliefs, behaviors, and attitudes related to PVH risk factors and potential mitigating technologies.METHODS/DATA SOURCES: We conducted a national survey of US caregivers to: (1) determine caregivers' perceptions of PVH risk for children in their care, as well as their thoughts about adopting risk mitigating technologies, (2) characterize scenarios in which caregivers intentionally leave children unattended in vehicles, and (3) assess caregiver awareness of national PVH campaigns. We used a variety of question formats (select all that apply, multiple choice, free r...
Source: Accident; Analysis and Prevention. - June 23, 2023 Category: Accident Prevention Authors: Emma Sartin Kristina B Metzger Jalaj Maheshwari Source Type: research
US caregivers' attitudes and risk perceptions towards pediatric vehicular heatstroke: A national survey
The objective of this study was to characterize caregivers' beliefs, behaviors, and attitudes related to PVH risk factors and potential mitigating technologies.METHODS/DATA SOURCES: We conducted a national survey of US caregivers to: (1) determine caregivers' perceptions of PVH risk for children in their care, as well as their thoughts about adopting risk mitigating technologies, (2) characterize scenarios in which caregivers intentionally leave children unattended in vehicles, and (3) assess caregiver awareness of national PVH campaigns. We used a variety of question formats (select all that apply, multiple choice, free r...
Source: Accident; Analysis and Prevention. - June 23, 2023 Category: Accident Prevention Authors: Emma Sartin Kristina B Metzger Jalaj Maheshwari Source Type: research
A comprehensive review of vine tea: Origin, research on Materia Medica, phytochemistry and pharmacology
CONCLUSIONS: This review systematically summarized and discussed vine tea from the following five aspects, history, genetic relationship, phytochemistry, research trend and ethnopharmacology. Vine tea has a long historical usage in Chinese ethnic medicine. Its outstanding therapeutic efficacies have attracted extensive attention in other places in the world at present. Nekemias cantonensis and Nekemias megalophylla are quite similar to Nekemias grossedentata in terms of many aspects. However, the current research has a narrow focus on mainly Nekemias grossedentata and DHM. We propose that future studies could be carried ou...
Source: Atherosclerosis - June 21, 2023 Category: Cardiology Authors: Tiexin Zeng Yanjun Song Shunyao Qi Ruyue Zhang Lijia Xu Peigen Xiao Source Type: research
