Fight Aging! Newsletter, April 8th 2024
In this study, we tested a stem cell secretome product, which contains extracellular vesicles and growth factors, cytoskeletal remodeling factors, and immunomodulatory factors. We examined the effects of 4 weeks of 2×/week unilateral intramuscular secretome injections (quadriceps) in ambulatory aged male C57BL/6 mice (22-24 months) compared to saline-injected aged-matched controls.
Secretome delivery substantially increased whole-body lean mass and decreased fat mass, corresponding to higher myofiber cross-sectional area and smaller adipocyte size, respectively. Secretome-treated mice also had greater whole-bod...
Source: Fight Aging! - April 7, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
How to control high blood pressure without medications
Just because you have been told that your blood pressure is above normal need not mean that you are tied up to medications lifelong. Changes in lifestyle can definitely bring down your blood pressure even without medications. In those already taking medications, the dose of medications can be brought down by important lifestyle changes. Some lucky ones may be able to stop medications as well. But you have to continue monitoring your blood pressure regularly so that any recurrence can be picked up.
One of the important ways in which to reduce elevated blood pressure is by reducing extra weight. Roughly the blood pressure mi...
Source: Cardiophile MD - April 6, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
The curse of the excellent doctor
The reward for good work is always more work. The employer becomes dependent on the quality of work that you do because he knows that you, as a person, are a workaholic and perfectionist. You put your heart and soul into everything you do. No other employers can do the kind of work that you
Read more…
The curse of the excellent doctor originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 6, 2024 Category: General Medicine Authors: Dr. Damane Zehra Tags: Physician Hospital-Based Medicine Oncology/Hematology Source Type: blogs
Echocardiogram in Mitral Valve Prolapse with Mitral Regurgitation (MVP, MR)
Transcript of the video: Now we will discuss echocardiogram in mitral valve prolapse. It is a fairly common condition. But, even though mitral valve prolapse can be detected echocardiographically in many cases, there may not be significant regurgitation and symptoms in many of them. Many of them may have just echo diagnosis without other relevances. So we will see some of the features of mitral regurgitation.
This is an echocardiogram from the apical four chamber view, you can see all the cardiac chambers, interventricular septum, and you can very well see the bowing of the anterior mitral leaflet and posterior mitral leaf...
Source: Cardiophile MD - April 6, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
A young woman with chest pain, cath lab activated
This case came from a friend whose sister was the patient. She knew I was interested in ECGs, so she took a photo of this one.A young woman presented with acute chest pain.This was her presenting ECG:What do you think?This is clearly Brugada phenotype. There is downsloping ST Elevation in V1 and V2. To an experienced interpreter, it is clearly not due to OMI. And it is clearly Brugada phenotype.The conventional algorithm did not interpret Brugada. In fact, it read: ** **ACUTE MI / STEMI ** **The physicians caring for the patient activated the cath lab for " STEMI " .The interventionalist and cath tea...
Source: Dr. Smith's ECG Blog - April 6, 2024 Category: Cardiology Authors: Steve Smith Source Type: blogs
poem
IthacaOnce I finally left the islandOf Calypso the highway became an endless Series of off-ramps and mergingsEach exit sign an indecipherable medleyOf directional words — North and south, east and westFuture and past, here or now —All mixed up in inexplicable combinations That made no geographical sense The GPS on my phone showedOnly a red dot moving alongA single black line relative to nothing elseWhich is the definition Of going nowhere fast Time lysed itself from spaceWhile space moved on to whatever comes after time Three minutes allegedly elapsedAccording to the digit...
Source: Buckeye Surgeon - April 6, 2024 Category: Surgery Authors: Jeffrey Parks MD FACS Source Type: blogs
An Urgent Call to Raise Awareness of Heart Disease in Women
By KELLY CARROLL
There is a dire need to raise awareness about heart disease in women. It is the number one killer of American women, and key data points reveal a lack of cognizance among doctors and women.
An assessment of primary care physicians published in 2019 revealed that only 22% felt extremely well prepared to evaluate cardiovascular disease risks in female patients. A 2019 survey of American women showed that just 44% recognized heart disease as the number one cause of death in women. Ten years earlier, in 2009, the same survey found that 65% of American women recognized heart disease as the leading cause o...
Source: The Health Care Blog - April 5, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Medical Practice heart disease Kelly Carroll Life Essential 8 prevention Womens health Source Type: blogs
Naked Mole Rats are Resistant to Ischemia, Such as Occurs Following a Heart Attack
On the one hand, naked mole-rats are most likely long-lived because they live underground, and thus suffer much lower rates of predation than other similarly sized mammals. Lower rates of extrinsic mortality appear to be a necessary prerequisite for the evolution of a longer species life span. On the other hand, living in a low-oxygen environment appears to have spurred the evolution of broad range of adaptations to that environment that incidentally happen to extend species longevity. Today's open access paper covers one aspect of those adaptations, a resistance to ischemia that reduces the harms resulting from the loss o...
Source: Fight Aging! - April 5, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
How microplastics harm your health
The New England Journal of Medicine recently published a paper titled “Microplastics and Nanoplastics in Atheromas and Cardiovascular Events,” which detected the presence of microplastics and nanoplastics (MNPs) in carotid artery plaque, with a higher risk of a composite of myocardial infarction, stroke, or death from any cause at 34 months follow-up than those in
Read more…
How microplastics harm your health originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 5, 2024 Category: General Medicine Authors: Neha Pidatala, MD Tags: Conditions Cardiology Source Type: blogs
Basics of Echocardiography
Transcript of the video: Echocardiography is now not restricted to the echocardiographic laboratory. It is used in the emergency department, at bedside, in the intensive care unit as well as in the operating room. Hence a basic knowledge is needed for all physicians and paramedics. During echocardiography, a transducer transmits the ultrasound beam towards the heart. Echoes received by the transducer from various structures of the heart are analysed by the echocardiograph and a graphical representation
displayed on the monitor.
Location of the transducer is at the top of the image sector. Structures nearer to the tr...
Source: Cardiophile MD - April 4, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Technobabble To English: A Buzzword Guide For Medical AI And Digital Health
Navigating AI in medicine and digital health can feel like ordering a coffee at that new hipster café downtown: exciting yet slightly overwhelming with a menu that seems to be in a different language. A while ago we published a buzzword dictionary to help you decode the most frequently repeated terms. Back then artificial intelligence and machine learning were rarely heard exotic expressions, but as quite a few years have passed, a whole new set of mambo-jambo emerged, waiting to be explained.
You’re probably sick of hearing the latest digital health buzzwords without any actual context, so let’s translat...
Source: The Medical Futurist - April 4, 2024 Category: Information Technology Authors: Andrea Koncz Tags: TMF Artificial Intelligence in Medicine buzzword AI in medicine generative AI in medicine Source Type: blogs
Wednesday Bible Study: A public health lesson
Psalm 90 is attributed to Moses. At least David might have existed, although he certainly did not write the psalms attributed to him. Moses is an entirely fictitious character. We know for a fact that the Egyptian captivity and the exodus never happened. But I ' ll give the writer this much credit -- the human lifespan of 70 years was probably pretty accurate at the time, in the sense that it was about the longest people could hope to live. You may recall that in Genesis 6:3 God says the human lifespan will be 120 years, and that many of the characters in Genesis lived for hundreds of years. However, life expectancy -...
Source: Stayin' Alive - April 3, 2024 Category: American Health Source Type: blogs
Eccentricity Index in Bicuspid Aortic Valve
Transcript of the video: Closure line of aortic valve on M-Mode echocardiogram, is seen as central line, while in bicuspid aortic valve, it is an eccentric closure, nearer to one of the walls of the aorta. This eccentricity of closure of the aortic valve leaflets, can be calculated using what is known as eccentricity index. That is an important feature of bicuspid aortic valve on M-Mode echocardiogram.
This is an M-Mode echocardiogram at the aorta-left atrium level. You can see the cursor on the 2-D echo, and this is the closure line. This is normal aortic valve, central closure as a single line. During systole, one openin...
Source: Cardiophile MD - April 2, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
Ventricular Fibrillation, ICD, LBBB, QRS of 210 ms, Positive Smith Modified Sgarbossa Criteria, and Pacemaker-Mediated Tachycardia
An elderly man collapsed. There was no bystander CPR. Medics found him in ventricular fibrillation. He was defibrillated, but they also noticed that he was being internally defibrillated and then found that he had an implantable ICD.He was unidentified and there were no records availableAfter 7 shocks, he was successfully defibrillated and brought to the ED.Bedside ED ultrasound showed exceedingly poor global LV function, and no B lines.Here is the initial ED ECG. What do you think?Rhythm: Residents asked me why it is not VT. If you use calipers (or equvalent), it is clear that the rhythm...
Source: Dr. Smith's ECG Blog - April 2, 2024 Category: Cardiology Authors: Steve Smith Source Type: blogs
Hemodynamic Vise
Transcript of the video: Hemodynamic vise is the term given to compression of a vertical vein, which ascends to the brachiocephalic vein, between a bronchus and pulmonary artery. This produces a vicious cycle and that is why it is known as hemodynamic vise in certain types of congenital heart diseases which have a vertical vein.
This is the typical location of the hemodynamic vise, between the pulmonary artery and left bronchus. When the vertical vein ascends, it is compressed by these two. When it is compressed, pulmonary venous drainage is obstructed partially, which leads to increase in the pulmonary venous pressure. Pu...
Source: Cardiophile MD - April 1, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs
