Raised Blood Pressure and Arterial Stiffness Correlate with Loss of Kidney Function
In conclusion, we found that elevated central aortic stiffness is associated with a greater decline in kidney function in old age. Since aPWV and cSBP both appear to be predictors of eGFR decline, it might be of interest to identify older individuals with elevated aortic stiffness. In this specific population, intensive blood pressure reduction might be justified in order to slow down the process of vascular aging and prevent kidney function decline. Link: https://doi.org/10.3390/jcm13051334 (Source: Fight Aging!)
Source: Fight Aging! - April 30, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Coronary Diagnostic Catheters
Diagnostic coronary angiography is most often undertaken either through the femoral route or radial route. Rarely brachial or axillary access may be resorted to if the popular radial or femoral routes are not feasible. Femoral access may be preferred in an emergency when quick arterial access is needed. It is also used when more devices have to be introduced, but seldom the case for diagnostic coronary angiography. The most popular catheter for femoral route is Judkins catheter. Judkins catheter comes in left coronary and right coronary curves. They have a primary curve and a secondary curve. Primary curve engages the coro...
Source: Cardiophile MD - April 30, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

How Does Exercise Prevent Heart Disease?
Dr. Paul Dudley White, the famous physician who has taught many a luminary in the field of cardiology once wrote that heart disease before eighty is our fault and not God’s will or nature’s will. This means that he recognized long back, the role of life-style modification in preventing heart disease. Exercise in a regular pattern is one of the important life style modifications which everyone can adopt to prevent or delay cardiovascular disease. Exercise helps in various ways for prevention of cardiovascular disease. In those with established cardiovascular disease, graded exercise programs can promote the formation of...
Source: Cardiophile MD - April 30, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Presence of Cardiometabolic Disease Correlates with Accelerated Brain Aging
It is well known that metabolic dysfunction and cardiovascular disease correlate well with an accelerated onset and progression of neurodegenerative conditions. This is particularly evident when considering these conditions in the context of obesity. Age-related diseases are the late stage consequences of a progressive accumulation of cell and tissue damage, and so a lifestyle that accelerates those underlying damage processes will produce a greater incidence of all of the common age-related diseases. Suffering from one form of age-related disease thus implies greater odds of suffering other forms of age-related disease, a...
Source: Fight Aging! - April 29, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Should you take medications for high blood pressure lifelong?
The answer depends on what caused your high blood pressure. If it is a reversible cause which can be removed, then of course medications can be stopped. But if a reversible cause has not been found, you should be cautious about stopping medications. What are the reversible causes of high blood pressure? A transient drop in kidney function due to some illness (acute kidney injury) can raise the blood pressure. But when the kidney problem settles, blood pressure normalizes, and it may never recur. In this situation blood pressure medication can certainly be stopped. There are certain rare tumours which secrete hormones which...
Source: Cardiophile MD - April 29, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

11 Ways Conscious Growth Club Will Expand Your Experiential Range
Conscious Growth Club is our primo online self-development club. It’s been running for 7 years now, so we’ve had plenty of time to evolve and improve it. The new Year 8 version of CGC is especially rich, abundant, and divergent – so different and unique compared to anything I’ve seen elsewhere in the self-development world. Instead of focusing primarily on content or coaching, in CGC we prioritize crafting and guiding you through unique growth experiences. You’ll learn more through direct experience than you will by just reading and watching videos. CGC includes a strong content library too,...
Source: Steve Pavlina's Personal Development Blog - April 28, 2024 Category: Psychiatry & Psychology Authors: Steve Pavlina Tags: Abundance Creating Reality Emotions Lifestyle Productivity Relationships Values Source Type: blogs

Fight Aging! Newsletter, April 29th 2024
In conclusion, we assigned stemness scores to human samples and show evidence of a pan-tissue loss of stemness during human aging, which adds weight to the idea that stem cell deterioration may contribute to human aging. « Back to Top The Role of Immune Aging in Neurodegenerative Conditions https://www.fightaging.org/archives/2024/04/the-role-of-immune-aging-in-neurodegenerative-conditions/ The research community has come to see chronic inflammation and other age-related immune system dysfunctions as an important aspect of neurodegenerative conditions. Inflammation in the short term is n...
Source: Fight Aging! - April 28, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Ways to prevent clots in legs and lungs
Pulmonary embolism is obstruction of blood vessels of the lungs by clots carried by blood circulation, usually from the legs. It is a serious life threatening condition and hence trying to prevent it is very important. Clots can also migrate from blood vessels of the tummy, but that is not easy to prevent. Blood clots can form in the veins or blood vessels returning deoxygenated blood to the lungs for enrichment with oxygen. Though the heart pumps blood to the whole body, it has no mechanism for bringing the blood back to it. This work is usually taken care of by muscles in other parts of the body. When you move your limbs...
Source: Cardiophile MD - April 28, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Atrial dilatation in Atrial fibrillation : A query with multiple twists!
(This is supposed to be a poll. Sorry, readers, you can’t select the answer. WordPress is not kind enough and suddenly made the poll service payable extra. I am already paying nearly a $100 fee to maintain this site. I can’t afford any more.) We have been taught Bi-Atrial enlargement is the rule in AF .It is still true in most situations. But, we rarely dispute it , & ask which atrium dilates more in AF ? Let us see few factors. Both atria develop from a combination of the primitive atrium, sinus venous, and pulmonary veins.It is logical to presume there must be a hidden morpho-electrical ...
Source: Dr.S.Venkatesan MD - April 28, 2024 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized atrial cardiomyopathy atrial fibrillation biatrial enlargement in af dispropotinate atrial enlargement in af left atrial cardiomyopathy left atrial fibrillation left atrial vs right atrial fibrillation lone af non pulmonary Source Type: blogs

Day Time Sleepiness Triples Risk of Heart Failure!
Daytime sleepiness is not that uncommon. There are many who fall asleep while at work or while reading. Wait before taking it so lightly. It may mean something more sinister. The Sleep Heart Health Study found that obstructive sleep apnea with excessive daytime sleepiness triples the chance of heart failure and doubles the risk of a heart disease event. Obstructive sleep apnea known in short as OSA is transient stoppage of breathing while sleeping due to obstruction of the upper air passages. The obstruction is manifest as noisy breathing or snoring. Poor quality of sleep at night leads to daytime sleepiness. The Sleep Hea...
Source: Cardiophile MD - April 27, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Two prehospital ECGs of patients with chest pain.
Written by Pendell Meyers and Steve SmithHere are two cases of middle-aged men with chest pain who had prehospital ECGs.Patient 1, ECG 1:What do you think? Patient 2, ECG 2:What do you think?Queen of Hearts interpretation of ECG 1:Queen of Hearts interpretation for ECG 2:Interpretation of ECG 1 (OMI): Sinus rhythm, normal QRS, with easily diagnostic signs specific for inferior and posterior wall transmural ischemia, with the most likely etiology of course being acute coronary occlusion MI. Inferior T waves are hyperacute, with reciprocal negative hyperacute T waves in aVL. Posterior OMI is indicated by the inappropria...
Source: Dr. Smith's ECG Blog - April 27, 2024 Category: Cardiology Authors: Pendell Source Type: blogs

ONC Turns 20!
Tomorrow marks the 20th birthday of the Office of the National Coordinator of Health Information Technology. A few thoughts …  a) ONC’s work is uniquely bipartisan.  There is little disagreement that information technology – well applied – can (will / must) improve the health of the people of the United States.  While different administrations have managed ONC’s work differently – the common theme remains an optimism about the role of information technology in improving population health, and the need for federal oversight of the tools with which this is done.  The impact of the work...
Source: Docnotes - April 26, 2024 Category: Primary Care Authors: Jacob Tags: Uncategorized Source Type: blogs

Mitochondrial Transplantation Improves Muscle Function in Old Mice
In this study 15 female mice (24 months old) were randomized into two groups (placebo or mitochondrial transplantation). Isolated mitochondria from a donor mouse of the same sex and age were transplanted into the hindlimb muscles of recipient mice. The results indicated significant increases (ranging between ~36% and ~65%) in basal cytochrome c oxidase and citrate synthase activity as well as ATP levels in mice receiving mitochondrial transplantation relative to the placebo. Moreover, there were significant increases (approximately two-fold) in protein expression of mitochondrial markers in both glycolytic and oxidative mu...
Source: Fight Aging! - April 26, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Calorie Restriction and Fasting Benefit the Aging Heart
In conclusion, fasting-induced autophagy is beneficial for ensuring cardiac function, preventing disease, and improving longevity. However, additional studies in vivo in animal models of cardiac aging are needed to determine the specific molecular mechanisms involved in normalizing autophagy by fasting. In addition, large-scale studies on humans are needed. Importantly, further in vitro research should be directed toward human cardiac tissues to better understand the molecular mechanisms of fasting-induced autophagy and its beneficial effects on longevity pathways and prevention of cardiovascular disease. Link: ht...
Source: Fight Aging! - April 26, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

100 Good Morning Sunday Wishes, Messages and Greetings for a Happy Day
Sunday is here. A day for rest and recharging, for having fun and to spend time with the people you love. So to help you with that I’d like to share to the most inspiring Good morning Sunday wishes, messages and greetings to make sure you have a great Sunday morning and day. And if you want more motivating messages like these then be sure to check out this post with good morning Friday blessings and also this one with many good morning Saturday blessings. Good Morning, Happy Sunday Messages “Happy Sunday morning, my friend! I wish you a day filled with fun, sunshine and plenty of smiles.” “Good mo...
Source: Practical Happiness and Awesomeness Advice That Works | The Positivity Blog - April 26, 2024 Category: Consumer Health News Authors: Henrik Edberg Tags: Inspirational Quotes Personal Development Source Type: blogs