Childhood Extracranial Germ Cell Brain Tumors
Childhood Extracranial Germ Cell Tumors (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - May 8, 2018 Category: General Medicine Source Type: news
UCLA scientists use stem cells to study genetics of germ cell tumors
UCLA researchers have made new inroads into understanding germ cell tumors, a diverse and rare group of cancers that begin in germ cells — the cells that develop into sperm and eggs. The researchers developed a protocol to recreate germ cell tumor cells from stem cells and used the new model to study the genetics of the cancer.Their findings could point the way toward new drugs to treat germ cell tumors, which account for around 3 percent of all cases of childhood and adolescent cancer.The study, published in Stem Cell Research, was led by Amander Clark, a UCLA professor of molecular cell and developmental biology and a ...
Source: UCLA Newsroom: Health Sciences - January 29, 2018 Category: Universities & Medical Training Source Type: news
Solving the mystery of a shapeshifting neck tumor
Jaedin, 10 years old, holds the control for a remote-controlled race car, Christmas 2017.
Amanda Brown couldn’t shake an uneasy intuition that something just seemed “off” throughout her second pregnancy. During a scheduled caesarian section at her local hospital in North Carolina, her instinct proved to be true.
“I had given birth to my first son by C-section so I knew what to expect,” Amanda says. “But this time around, as the surgeons totally stalled in the middle of the delivery, I thought to myself, ‘it doesn’t take this long to pull a baby out.’”
When her son Jaedin was finally delivered, Amanda an...
Source: Thrive, Children's Hospital Boston - January 24, 2018 Category: Pediatrics Authors: Kat J. McAlpine Tags: Diseases & Conditions Our Patients’ Stories Center for Airway Disorders cervical teratoma Dr. Reza Rahbar germ cell tumor Neck and Skullbase Surgery Program at Boston Children's NICU Solid Tumors Center at Dana-Farber/Boston Children's Source Type: news
Could BEP Reduce the Risk of Brain Metastasis in Testicular Cancer?
A post-hoc analysis found that brain metastases are more frequent in patients with advanced germ cell tumors who have received dose-dense chemotherapy compared with those administered the BEP regimen. (Source: CancerNetwork)
Source: CancerNetwork - December 6, 2017 Category: Cancer & Oncology Authors: Bryant Furlow Tags: Genitourinary Cancers News Testicular Cancer Source Type: news
Pembrolizumab Not Active Against Cisplatin-Refractory Testicular Cancer
In a small phase II study of 12 men with nonseminoma germ cell tumors refractory to cisplatin, pembrolizumab did not demonstrate clinical activity. (Source: CancerNetwork)
Source: CancerNetwork - November 27, 2017 Category: Cancer & Oncology Authors: Bryant Furlow Tags: Genitourinary Cancers News Testicular Cancer Source Type: news
Study sheds new light on inherited testicular cancer risk
(University of Pennsylvania School of Medicine) An analysis of data from five major studies of testicular cancer has identified new genetic locations that could be susceptible to inherited testicular germ cell tumors. The findings, which researchers call a success story for genome mapping, could help doctors understand which men are at the highest risk of developing the disease and signal them to screen those patients. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 12, 2017 Category: Cancer & Oncology Source Type: news
Reduced, Compressed Chemotherapy Fails in Pediatric Germ Cell Tumors
Event-free survival was not maintained in children and adolescents with intermediate-risk malignant germ cell tumors when cisplatin-based chemotherapy was reduced from four to three cycles and compressed from 5 to 3 days per cycles. (Source: CancerNetwork)
Source: CancerNetwork - March 11, 2017 Category: Cancer & Oncology Authors: Leah Lawrence Tags: Genitourinary Cancers Gynecologic Cancers News Ovarian Cancer Pediatric Cancers Testicular Cancer Source Type: news
Single-Cycle of BEP Shows Promise Against Testicular Cancer Recurrence
A single cycle of adjuvant bleomycin, etoposide, and cisplatin (BEP) chemotherapy might reduce recurrence rates for nonseminomatous or combined germ cell tumors of the testis. (Source: CancerNetwork)
Source: CancerNetwork - February 18, 2017 Category: Cancer & Oncology Authors: Bryant Furlow Tags: ASCO Genitourinary Cancers Symposium News Testicular Cancer Source Type: news
High-Dose Chemo Plus Stem Cells for Relapsed Metastatic Germ Cell Cancer High-Dose Chemo Plus Stem Cells for Relapsed Metastatic Germ Cell Cancer
High-dose chemotherapy (HDCT) and autologous peripheral-blood stem-cell transplantation (PBSCT) may be able to cure men with relapsed metastatic testicular and other germ cell tumors, even when the approach is used as third-line or later therapy, new research suggests.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - November 29, 2016 Category: Pathology Tags: Hematology-Oncology News Source Type: news
Surveillance an Option for Early-Stage Ovarian Germ Cell Tumors
The use of surveillance did not affect survival among women with stage I malignant ovarian germ cell tumors, according to a new retrospective analysis. (Source: CancerNetwork)
Source: CancerNetwork - November 11, 2016 Category: Cancer & Oncology Authors: Dave Levitan Tags: Gynecologic Cancers News Ovarian Cancer Source Type: news
Researchers Identify Promising MicroRNA Biomarker for Germ Cell Tumors Researchers Identify Promising MicroRNA Biomarker for Germ Cell Tumors
The microRNA miR-371a-3p is a new and promising serum marker for germ cell tumors, researchers from Germany report.Reuters Health Information (Source: Medscape Pathology Headlines)
Source: Medscape Pathology Headlines - August 18, 2016 Category: Pathology Tags: Pathology & Lab Medicine News Source Type: news
What is Immature Tertatoma and How is it Treated?
What kind of malignant germ cell tumor are immature teratomas, how are they treated and how is prognosis determined? (Source: About.com Ovarian Cancer)
Source: About.com Ovarian Cancer - February 23, 2016 Category: Cancer & Oncology Authors: ovariancancer.guide at about.com Tags: health Source Type: news
Chemotherapy for Germ Cell Tumor May Spur CMLChemotherapy for Germ Cell Tumor May Spur CML
Findings raise the question of a causal link between etoposide and/or platinum-containing chemotherapy and the development of chronic myelogenous leukemia (CML). Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - December 4, 2015 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
New test to predict relapse of testicular cancers
Scientists have developed a new test to identify patients who are at risk of suffering a relapse from testicular cancer. Assessing just three features of a common kind of testicular cancer -- called non-seminomatous germ cell tumor -- can identify those at most at risk of relapse even where there is no evidence of tumor spread. The researchers believe the test could be used in the clinic to make decisions about which patients should be given chemotherapy. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 15, 2015 Category: Science Source Type: news
New test to predict relapse of testicular cancers
(Institute of Cancer Research) Scientists have developed a new test to identify patients who are at risk of suffering a relapse from testicular cancer. Assessing just three features of a common kind of testicular cancer -- called non-seminomatous germ cell tumor -- can identify those at most at risk of relapse even where there is no evidence of tumor spread. The researchers believe the test could be used in the clinic to make decisions about which patients should be given chemotherapy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 15, 2015 Category: Global & Universal Source Type: news
