Chemotherapy Followed by Response-Based Reduced Radiation Therapy for Patients With Central Nervous System Germinomas
Conditions: Intracranial Germ Cell Tumor; Childhood Central Nervous System Germinoma Interventions: Radiation: 3-Dimensional Conformal Radiation Therapy; Drug: Carboplatin; Drug: Etoposide; Radiation: Intensity-Modulated Radiation Therapy Sponsors: Children ' s Oncology Group Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 16, 2024 Category: Research Source Type: clinical trials

Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours
Conditions: Advanced Cancer; Advanced Solid Tumor; Lymphoma, Hodgkin; Central Nervous System Tumor; Sarcoma; Germ Cell Tumor; Pediatric Cancer Interventions: Dietary Supplement: Ocoxin Oral solution Sponsors: Catalysis SL Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Clinical Study of Chemotherapy in the Treatment of Recurrent/Refractory Yolk Sac Tumor in Children
Conditions: Germ Cell Tumor; Yolk Sac Tumor Interventions: Drug: sirolimus combined with chemotherapy in the treatment of recurrent/refractory yolk sac tumor in children Sponsors: Shandong First Medical University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 2, 2024 Category: Research Source Type: clinical trials

SerUm and Plasma MicroRNAs in Malignant Ovarian gERm Cell Tumours
Conditions: Germ Cell Ovarian Cancer; Germ Cell Tumor; Germ Cell Cancer; Germ Cell Neoplasia; Ovary Cancer; Ovary Neoplasm; Ovarian Cancer; Ovarian Neoplasms Interventions: Diagnostic Test: Blood test; Diagnostic Test: Pathology specimen miRNA expression Sponsors: Imperial College London Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials

Phase 1, Safety and Tolerability Study of XmAb ®541 in Advanced Solid Tumors
Conditions: Ovarian Cancer; Endometrial Cancer; Germ Cell Tumor; Testicular Germ Cell Tumor; Ovarian Germ Cell Tumor Interventions: Biological: XmAb541 Sponsors: Xencor, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials

7 Tesla MRI Neuroimaging in Testicular Cancer Patients With Hypogonadism and on Androgen Replacement Therapy
Conditions: Hypogonadism; Malignant Testicular Germ Cell Tumor Interventions: Procedure: 7 Tesla Magnetic Resonance Imaging; Procedure: Biospecimen Collection; Procedure: Cognitive Assessment Sponsors: University of Southern California; National Cancer Institute (NCI) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 4, 2024 Category: Research Source Type: clinical trials

A Prospective, Single-center, Clinical Trial to Evaluate the Efficacy of Sentinel Lymph Node Biopsy in Stage AI-IIA Germ Cell Tumors (Seminoma/Nonseminoma)(PITERLAND).
Conditions: Testicular Germ Cell Tumor Interventions: Procedure: Orchofuniculectomy with simultaneous laparoscopic biopsy of the sentinel lymph node using indocyanine green dye with/without methylene blue dye.; Diagnostic Test: Radiopharmaceutical administration (Technetium/methylene blue) Sponsors: N.N. Petrov National Medical Research Center of Oncology Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 15, 2023 Category: Research Source Type: clinical trials

Robot-assisted ICG-guided Sentinel Node Biopsy in Testicular Cancer
Conditions: Germ Cell Tumor; Seminoma; Nonseminomatous Germ Cell Tumor Interventions: Procedure: Robot-assisted ICG-guided sentinel lymph node biopsy Sponsors: Heinrich-Heine University, Duesseldorf; Intuitive Foundation Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 15, 2023 Category: Research Source Type: clinical trials

MAGESTIC Trial: MiRNA in Detecting Active Germ Cell Tumors in Early Suspected and MetastaTIC Disease Trial
Conditions: Malignant Testicular Germ Cell Tumor Interventions: Other: Non-Interventional Study Sponsors: University of Southern California; National Cancer Institute (NCI) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 29, 2023 Category: Research Source Type: clinical trials

Survival and Reproductive Outcomes of Malignant Ovarian Germ Cell Tumors
Condition:   Fertility Issues Intervention:   Other: observational study Sponsor:   Cairo University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 15, 2023 Category: Research Source Type: clinical trials