Associations between COVID-19 and Glucose-6-Phosphate Dehydrogenase Activity in Brazil
In conclusion, this study does not demonstrate an association of G6PDd with severity of COVID-19. Limitations of the test for detecting enzyme levels during COVID-19 illness were demonstrated by genotyping and retesting after the disease period. Care must be taken when screening for G6PDd in patients with acute COVID-19.PMID:38593787 | DOI:10.4269/ajtmh.23-0148 (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - April 9, 2024 Category: Infectious Diseases Authors: Maria Gabriela de Almeida Rodrigues Wuelton Marcelo Monteiro Gisely Cardoso de Melo Ádila Liliane Barros Dias Marco Aur élio Sartim Mariana Sim ão Xavier Rebeca Linhares Abreu Netto Fernando Fonseca Almeida Djane Clarys Ba ía-da-Silva Jos é Diego Bri Source Type: research
Associations between COVID-19 and Glucose-6-Phosphate Dehydrogenase Activity in Brazil
In conclusion, this study does not demonstrate an association of G6PDd with severity of COVID-19. Limitations of the test for detecting enzyme levels during COVID-19 illness were demonstrated by genotyping and retesting after the disease period. Care must be taken when screening for G6PDd in patients with acute COVID-19.PMID:38593787 | DOI:10.4269/ajtmh.23-0148 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 9, 2024 Category: Tropical Medicine Authors: Maria Gabriela de Almeida Rodrigues Wuelton Marcelo Monteiro Gisely Cardoso de Melo Ádila Liliane Barros Dias Marco Aur élio Sartim Mariana Sim ão Xavier Rebeca Linhares Abreu Netto Fernando Fonseca Almeida Djane Clarys Ba ía-da-Silva Jos é Diego Bri Source Type: research
Associations between COVID-19 and Glucose-6-Phosphate Dehydrogenase Activity in Brazil
In conclusion, this study does not demonstrate an association of G6PDd with severity of COVID-19. Limitations of the test for detecting enzyme levels during COVID-19 illness were demonstrated by genotyping and retesting after the disease period. Care must be taken when screening for G6PDd in patients with acute COVID-19.PMID:38593787 | DOI:10.4269/ajtmh.23-0148 (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - April 9, 2024 Category: Infectious Diseases Authors: Maria Gabriela de Almeida Rodrigues Wuelton Marcelo Monteiro Gisely Cardoso de Melo Ádila Liliane Barros Dias Marco Aur élio Sartim Mariana Sim ão Xavier Rebeca Linhares Abreu Netto Fernando Fonseca Almeida Djane Clarys Ba ía-da-Silva Jos é Diego Bri Source Type: research
Associations between COVID-19 and Glucose-6-Phosphate Dehydrogenase Activity in Brazil
In conclusion, this study does not demonstrate an association of G6PDd with severity of COVID-19. Limitations of the test for detecting enzyme levels during COVID-19 illness were demonstrated by genotyping and retesting after the disease period. Care must be taken when screening for G6PDd in patients with acute COVID-19.PMID:38593787 | DOI:10.4269/ajtmh.23-0148 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 9, 2024 Category: Tropical Medicine Authors: Maria Gabriela de Almeida Rodrigues Wuelton Marcelo Monteiro Gisely Cardoso de Melo Ádila Liliane Barros Dias Marco Aur élio Sartim Mariana Sim ão Xavier Rebeca Linhares Abreu Netto Fernando Fonseca Almeida Djane Clarys Ba ía-da-Silva Jos é Diego Bri Source Type: research
Associations between COVID-19 and Glucose-6-Phosphate Dehydrogenase Activity in Brazil
In conclusion, this study does not demonstrate an association of G6PDd with severity of COVID-19. Limitations of the test for detecting enzyme levels during COVID-19 illness were demonstrated by genotyping and retesting after the disease period. Care must be taken when screening for G6PDd in patients with acute COVID-19.PMID:38593787 | DOI:10.4269/ajtmh.23-0148 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 9, 2024 Category: Tropical Medicine Authors: Maria Gabriela de Almeida Rodrigues Wuelton Marcelo Monteiro Gisely Cardoso de Melo Ádila Liliane Barros Dias Marco Aur élio Sartim Mariana Sim ão Xavier Rebeca Linhares Abreu Netto Fernando Fonseca Almeida Djane Clarys Ba ía-da-Silva Jos é Diego Bri Source Type: research
Associations between COVID-19 and Glucose-6-Phosphate Dehydrogenase Activity in Brazil
In conclusion, this study does not demonstrate an association of G6PDd with severity of COVID-19. Limitations of the test for detecting enzyme levels during COVID-19 illness were demonstrated by genotyping and retesting after the disease period. Care must be taken when screening for G6PDd in patients with acute COVID-19.PMID:38593787 | DOI:10.4269/ajtmh.23-0148 (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - April 9, 2024 Category: Infectious Diseases Authors: Maria Gabriela de Almeida Rodrigues Wuelton Marcelo Monteiro Gisely Cardoso de Melo Ádila Liliane Barros Dias Marco Aur élio Sartim Mariana Sim ão Xavier Rebeca Linhares Abreu Netto Fernando Fonseca Almeida Djane Clarys Ba ía-da-Silva Jos é Diego Bri Source Type: research
Associations between COVID-19 and Glucose-6-Phosphate Dehydrogenase Activity in Brazil
In conclusion, this study does not demonstrate an association of G6PDd with severity of COVID-19. Limitations of the test for detecting enzyme levels during COVID-19 illness were demonstrated by genotyping and retesting after the disease period. Care must be taken when screening for G6PDd in patients with acute COVID-19.PMID:38593787 | DOI:10.4269/ajtmh.23-0148 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 9, 2024 Category: Tropical Medicine Authors: Maria Gabriela de Almeida Rodrigues Wuelton Marcelo Monteiro Gisely Cardoso de Melo Ádila Liliane Barros Dias Marco Aur élio Sartim Mariana Sim ão Xavier Rebeca Linhares Abreu Netto Fernando Fonseca Almeida Djane Clarys Ba ía-da-Silva Jos é Diego Bri Source Type: research
Associations between COVID-19 and Glucose-6-Phosphate Dehydrogenase Activity in Brazil
In conclusion, this study does not demonstrate an association of G6PDd with severity of COVID-19. Limitations of the test for detecting enzyme levels during COVID-19 illness were demonstrated by genotyping and retesting after the disease period. Care must be taken when screening for G6PDd in patients with acute COVID-19.PMID:38593787 | DOI:10.4269/ajtmh.23-0148 (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - April 9, 2024 Category: Infectious Diseases Authors: Maria Gabriela de Almeida Rodrigues Wuelton Marcelo Monteiro Gisely Cardoso de Melo Ádila Liliane Barros Dias Marco Aur élio Sartim Mariana Sim ão Xavier Rebeca Linhares Abreu Netto Fernando Fonseca Almeida Djane Clarys Ba ía-da-Silva Jos é Diego Bri Source Type: research
G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1-Bax-mediated mitochondrial apoptosis pathway
CONCLUSION: Our study showed that the G6PD-VDAC1-Bax axis is a vital switch in VSMC apoptosis and is essential for VSMC phenotypic switching and neointimal hyperplasia, providing mechanistic insight into early VRDs.PMID:38589823 | DOI:10.1186/s11658-024-00566-w (Source: Mol Biol Cell)
Source: Mol Biol Cell - April 8, 2024 Category: Molecular Biology Authors: Ting Zhang Rui-Jie Cao Jiang-Ling Niu Zhi-Huan Chen Shi-Qing Mu Tong Cao Jie-Xin Pang Li-Hua Dong Source Type: research
G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1-Bax-mediated mitochondrial apoptosis pathway
CONCLUSION: Our study showed that the G6PD-VDAC1-Bax axis is a vital switch in VSMC apoptosis and is essential for VSMC phenotypic switching and neointimal hyperplasia, providing mechanistic insight into early VRDs.PMID:38589823 | DOI:10.1186/s11658-024-00566-w (Source: Cellular and Molecular Biology Letters)
Source: Cellular and Molecular Biology Letters - April 8, 2024 Category: Biochemistry Authors: Ting Zhang Rui-Jie Cao Jiang-Ling Niu Zhi-Huan Chen Shi-Qing Mu Tong Cao Jie-Xin Pang Li-Hua Dong Source Type: research
G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1-Bax-mediated mitochondrial apoptosis pathway
CONCLUSION: Our study showed that the G6PD-VDAC1-Bax axis is a vital switch in VSMC apoptosis and is essential for VSMC phenotypic switching and neointimal hyperplasia, providing mechanistic insight into early VRDs.PMID:38589823 | PMC:PMC11003121 | DOI:10.1186/s11658-024-00566-w (Source: Mol Biol Cell)
Source: Mol Biol Cell - April 8, 2024 Category: Molecular Biology Authors: Ting Zhang Rui-Jie Cao Jiang-Ling Niu Zhi-Huan Chen Shi-Qing Mu Tong Cao Jie-Xin Pang Li-Hua Dong Source Type: research
G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1-Bax-mediated mitochondrial apoptosis pathway
CONCLUSION: Our study showed that the G6PD-VDAC1-Bax axis is a vital switch in VSMC apoptosis and is essential for VSMC phenotypic switching and neointimal hyperplasia, providing mechanistic insight into early VRDs.PMID:38589823 | PMC:PMC11003121 | DOI:10.1186/s11658-024-00566-w (Source: Cellular and Molecular Biology Letters)
Source: Cellular and Molecular Biology Letters - April 8, 2024 Category: Biochemistry Authors: Ting Zhang Rui-Jie Cao Jiang-Ling Niu Zhi-Huan Chen Shi-Qing Mu Tong Cao Jie-Xin Pang Li-Hua Dong Source Type: research
Nobiletin alleviates methotrexate-induced hepatorenal toxicity in rats
Biotech Histochem. 2024 Apr 2:1-13. doi: 10.1080/10520295.2024.2335168. Online ahead of print.ABSTRACTWe investigated the possible ameliorative effects of nobiletin (NBL) against methotrexate (MTX)-induced hepatorenal toxicity in rats. Twenty-eight Wistar albino rats were randomly divided into four groups, namely: Control; MTX (administered 20 mg/kg MTX); MTX+NBL (administered 20 mg/kg MTX and 10 mg/kg NBL per day); and NBL (administered 10 mg/kg/day NBL). Histopathological, immunohistochemical and biochemical analyses were performed on the kidney and liver tissues of rats at the end of the study. MTX caused renal toxicity...
Source: Biotechnic and Histochemistry - April 2, 2024 Category: Research Authors: Filiz Kazak Ahmet Uyar Pinar Coskun Turan Yaman Source Type: research
Nobiletin alleviates methotrexate-induced hepatorenal toxicity in rats
Biotech Histochem. 2024 Apr 2:1-13. doi: 10.1080/10520295.2024.2335168. Online ahead of print.ABSTRACTWe investigated the possible ameliorative effects of nobiletin (NBL) against methotrexate (MTX)-induced hepatorenal toxicity in rats. Twenty-eight Wistar albino rats were randomly divided into four groups, namely: Control; MTX (administered 20 mg/kg MTX); MTX+NBL (administered 20 mg/kg MTX and 10 mg/kg NBL per day); and NBL (administered 10 mg/kg/day NBL). Histopathological, immunohistochemical and biochemical analyses were performed on the kidney and liver tissues of rats at the end of the study. MTX caused renal toxicity...
Source: Biotechnic and Histochemistry - April 2, 2024 Category: Research Authors: Filiz Kazak Ahmet Uyar Pinar Coskun Turan Yaman Source Type: research
Nobiletin alleviates methotrexate-induced hepatorenal toxicity in rats
Biotech Histochem. 2024 Apr 2:1-13. doi: 10.1080/10520295.2024.2335168. Online ahead of print.ABSTRACTWe investigated the possible ameliorative effects of nobiletin (NBL) against methotrexate (MTX)-induced hepatorenal toxicity in rats. Twenty-eight Wistar albino rats were randomly divided into four groups, namely: Control; MTX (administered 20 mg/kg MTX); MTX+NBL (administered 20 mg/kg MTX and 10 mg/kg NBL per day); and NBL (administered 10 mg/kg/day NBL). Histopathological, immunohistochemical and biochemical analyses were performed on the kidney and liver tissues of rats at the end of the study. MTX caused renal toxicity...
Source: Biotechnic and Histochemistry - April 2, 2024 Category: Research Authors: Filiz Kazak Ahmet Uyar Pinar Coskun Turan Yaman Source Type: research
