Avian Influenza A (H5N1) Outbreak 2024 in Cambodia: Worries Over the Possible Spread of the Virus to Other Asian Nations and the Strategic Outlook for its Control
Environ Health Insights. 2024 Apr 6;18:11786302241246453. doi: 10.1177/11786302241246453. eCollection 2024.ABSTRACTAsia has been alarmed by the resurgence of avian influenza A (H5N1) in Cambodia in 2024. H5N1 could be swiftly transmitted by wild birds to poultry populations along their migration route via infection. Circulation of endemic H5N1 in Asian poultry facilitates recurrent human transmission. Cambodia's role as a reservoir heightens the potential dangers of uncoordinated containment and surveillance across Southeast Asia. This correspondence addresses the risk factors, seasonal patterns, transmission dynamics, and...
Source: Environmental Health Insights - April 8, 2024 Category: Environmental Health Authors: Farhana Yesmin Nidra Mayesha Bintey Monir Syed Masudur Rahman Dewan Source Type: research
COVID-19 critical care triage across Canada: a narrative synthesis and ethical analysis of early provincial triage protocols
CONCLUSIONS: Early provincial COVID-19 triage protocols were developed by dedicated expert committees under challenging circumstances. Nonetheless, few were publicly available, and public consultation was limited. No protocols were ever implemented, including during periods of extreme critical care surge. A national approach to pandemic triage that incorporates additional aspects of procedural justice should be considered in preparation for future pandemics.PMID:38589739 | DOI:10.1007/s12630-024-02744-y (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - April 8, 2024 Category: Anesthesiology Authors: Sarah K Andersen Nathan Gamble Oleksa Rewa Source Type: research
Exploring viral aetiology in upper respiratory tract infections: insights from metagenomic next-generation sequencing in Swiss outpatients before and during the SARS-CoV-2 pandemic
CONCLUSIONS: Viral mNGS allowed the initial diagnosis to be retrospectively re-evaluated. Assuming reduced turnaround times, mNGS has the potential to directly guide the treatment of upper respiratory tract infections. On an epidemiological level, our study highlights the utility of mNGS in respiratory infection surveillance, allowing early detection of epidemics and providing information crucial for prevention.PMID:38587784 | DOI:10.57187/s.3797 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 8, 2024 Category: General Medicine Authors: Verena Kufner Andrea C Frey Sara H Burkhard Stefan Schmutz Gabriela Ziltener Maryam Zaheri Caroline V Wiedmer Andreas Plate Alexandra Trkola Michael Huber Nicolas J Mueller Source Type: research
Exploring viral aetiology in upper respiratory tract infections: insights from metagenomic next-generation sequencing in Swiss outpatients before and during the SARS-CoV-2 pandemic
CONCLUSIONS: Viral mNGS allowed the initial diagnosis to be retrospectively re-evaluated. Assuming reduced turnaround times, mNGS has the potential to directly guide the treatment of upper respiratory tract infections. On an epidemiological level, our study highlights the utility of mNGS in respiratory infection surveillance, allowing early detection of epidemics and providing information crucial for prevention.PMID:38587784 | DOI:10.57187/s.3797 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 8, 2024 Category: General Medicine Authors: Verena Kufner Andrea C Frey Sara H Burkhard Stefan Schmutz Gabriela Ziltener Maryam Zaheri Caroline V Wiedmer Andreas Plate Alexandra Trkola Michael Huber Nicolas J Mueller Source Type: research
Exploring viral aetiology in upper respiratory tract infections: insights from metagenomic next-generation sequencing in Swiss outpatients before and during the SARS-CoV-2 pandemic
CONCLUSIONS: Viral mNGS allowed the initial diagnosis to be retrospectively re-evaluated. Assuming reduced turnaround times, mNGS has the potential to directly guide the treatment of upper respiratory tract infections. On an epidemiological level, our study highlights the utility of mNGS in respiratory infection surveillance, allowing early detection of epidemics and providing information crucial for prevention.PMID:38587784 | DOI:10.57187/s.3797 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 8, 2024 Category: General Medicine Authors: Verena Kufner Andrea C Frey Sara H Burkhard Stefan Schmutz Gabriela Ziltener Maryam Zaheri Caroline V Wiedmer Andreas Plate Alexandra Trkola Michael Huber Nicolas J Mueller Source Type: research
Exploring viral aetiology in upper respiratory tract infections: insights from metagenomic next-generation sequencing in Swiss outpatients before and during the SARS-CoV-2 pandemic
CONCLUSIONS: Viral mNGS allowed the initial diagnosis to be retrospectively re-evaluated. Assuming reduced turnaround times, mNGS has the potential to directly guide the treatment of upper respiratory tract infections. On an epidemiological level, our study highlights the utility of mNGS in respiratory infection surveillance, allowing early detection of epidemics and providing information crucial for prevention.PMID:38587784 | DOI:10.57187/s.3797 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 8, 2024 Category: General Medicine Authors: Verena Kufner Andrea C Frey Sara H Burkhard Stefan Schmutz Gabriela Ziltener Maryam Zaheri Caroline V Wiedmer Andreas Plate Alexandra Trkola Michael Huber Nicolas J Mueller Source Type: research
COVID-19 critical care triage across Canada: a narrative synthesis and ethical analysis of early provincial triage protocols
ConclusionsEarly provincial COVID-19 triage protocols were developed by dedicated expert committees under challenging circumstances. Nonetheless, few were publicly available, and public consultation was limited. No protocols were ever implemented, including during periods of extreme critical care surge. A national approach to pandemic triage that incorporates additional aspects of procedural justice should be considered in preparation for future pandemics. (Source: Canadian Journal of Anesthesia)
Source: Canadian Journal of Anesthesia - April 8, 2024 Category: Anesthesiology Source Type: research
Viruses, Vol. 16, Pages 568: Abundant Intra-Subtype Reassortment Revealed in H13N8 Influenza Viruses
This study underscores the importance of the continued surveillance and research of less-studied influenza subtypes. (Source: Viruses)
Source: Viruses - April 7, 2024 Category: Virology Authors: Sofia Feoktistova Marya Sayganova Kseniya Trutneva Olga Glazova Artem S. Blagodatski Liudmila Shevkova Anna Navoikova Yuriy Anisimov Eugene Albert Olga Mityaeva Pavel Volchkov Andrey Deviatkin Tags: Article Source Type: research
Pandemic —Proofing for the Future
For years, infectious disease experts warned that we were overdue for a pandemic. They were right. When COVID-19 struck, I recalled the Great Influenza Pandemic of 1918 (often mislabeled as the “Spanish flu”). There were four waves of recurrence through 1920, and it wasn’t until the mid-1920s that the pandemic was felt to be “over.” Naively, I assumed the COVID-19 pandemic wouldn’t last that long because we are smarter now and science has progressed! But we repeated many of the struggles faced during that historical episode, including denials about the seriousness of the situation and misinformation about cause...
Source: Pediatric Clinics of North America - April 6, 2024 Category: Pediatrics Authors: Tina L. Cheng Tags: Foreword Source Type: research
Unveiling the role of preceding seasonal influenza in the development of bacteremic pneumococcal pneumonia in older adults before the COVID-19 pandemic in Japan
Streptococcus pneumoniae asymptomatically colonizes the nasopharynx, often causes pneumococcal disease in children and adults, and can enter the bloodstream to cause invasive pneumococcal disease (IPD). The most common presentation is bacteremic pneumonia, which accounts for approximately 60% of all adult IPD cases [1]. Adult patients with bacteremic pneumococcal pneumonia have a higher in-hospital mortality rate than those without bacteremia [2]. Therefore, understanding the diverse clinical aspects of pneumococcal infection is crucial for effective management and prevention strategies especially in adult population. (Sou...
Source: International Journal of Infectious Diseases - April 4, 2024 Category: Infectious Diseases Authors: Kosuke Tamura, Reiko Shimbashi, Ayu Kasamatsu, Bin Chang, Kenji Gotoh, Yoshinari Tanabe, Koji Kuronuma, Kengo Oshima, Takaya Maruyama, Masashi Nakamatsu, Shuichi Abe, Kei Kasahara, Junichiro Nishi, Yu Arakawa, Yuki Kinjo, Motoi Suzuki, Yukihiro Akeda, Kaz Source Type: research
Preparation and characterization of curdlan-chitosan conjugate nanoparticles as mucosal adjuvants for intranasal influenza H1N1 subunit vaccine
In this study, stable nanoparticles formed by curdlan-O-HTCC conjugate (CO NP) were prepared and characterized. Furthermore, the efficacy of CO NP was evaluated as a mucosal adjuvant in an intranasal influenza H1N1 subunit vaccine. The results revealed that CO NP exhibits uniform and spherical morphology, with a size of 190.53 ± 4.22 nm, and notably, it remains stable in PBS at 4 °C for up to 6 weeks. Biological evaluation demonstrated that CO NP stimulates the activation of antigen-presenting cells (APCs), including macrophages and dendritic cells (DCs), both in vitro and in vivo. Furthermore, intranasal administration ...
Source: International Journal of Biological Macromolecules - April 3, 2024 Category: Biochemistry Authors: Honglei Jiang Shu Zhang Yipan Chen Fengshan Wang Wenjie Jiang Source Type: research
Usefulness of a pluralistic approach in sentinel surveillance: seasonal influenza activity based on case counts per sentinel site in the National Epidemiological Surveillance of Infectious Diseases Program and test counts, case counts, and test positivity from the National Hospital Organization
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.368. Online ahead of print.ABSTRACTIn Japan, based on the National Epidemiological Surveillance of Infectious Diseases (NESID) Program, influenza cases from ~5,000 sentinel sites are monitored weekly as part of influenza surveillance (as number of influenza cases/sentinel site). One limitation is that the number of influenza tests conducted is not reported. Separately, the National Hospital Organization (NHO), with ~140 hospitals, routinely publishes three indicators: number of influenza tests, influenza-positive case counts, and test positivity. We used NESID and...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Takeshi Arashiro Yuzo Arima Takuri Takahashi Kiyosu Taniguchi Hiromasa Horiguchi Motoi Suzuki Source Type: research
Usefulness of a pluralistic approach in sentinel surveillance: seasonal influenza activity based on case counts per sentinel site in the National Epidemiological Surveillance of Infectious Diseases Program and test counts, case counts, and test positivity from the National Hospital Organization
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.368. Online ahead of print.ABSTRACTIn Japan, based on the National Epidemiological Surveillance of Infectious Diseases (NESID) Program, influenza cases from ~5,000 sentinel sites are monitored weekly as part of influenza surveillance (as number of influenza cases/sentinel site). One limitation is that the number of influenza tests conducted is not reported. Separately, the National Hospital Organization (NHO), with ~140 hospitals, routinely publishes three indicators: number of influenza tests, influenza-positive case counts, and test positivity. We used NESID and...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Takeshi Arashiro Yuzo Arima Takuri Takahashi Kiyosu Taniguchi Hiromasa Horiguchi Motoi Suzuki Source Type: research
Usefulness of a pluralistic approach in sentinel surveillance: seasonal influenza activity based on case counts per sentinel site in the National Epidemiological Surveillance of Infectious Diseases Program and test counts, case counts, and test positivity from the National Hospital Organization
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.368. Online ahead of print.ABSTRACTIn Japan, based on the National Epidemiological Surveillance of Infectious Diseases (NESID) Program, influenza cases from ~5,000 sentinel sites are monitored weekly as part of influenza surveillance (as number of influenza cases/sentinel site). One limitation is that the number of influenza tests conducted is not reported. Separately, the National Hospital Organization (NHO), with ~140 hospitals, routinely publishes three indicators: number of influenza tests, influenza-positive case counts, and test positivity. We used NESID and...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Takeshi Arashiro Yuzo Arima Takuri Takahashi Kiyosu Taniguchi Hiromasa Horiguchi Motoi Suzuki Source Type: research
Usefulness of a pluralistic approach in sentinel surveillance: seasonal influenza activity based on case counts per sentinel site in the National Epidemiological Surveillance of Infectious Diseases Program and test counts, case counts, and test positivity from the National Hospital Organization
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.368. Online ahead of print.ABSTRACTIn Japan, based on the National Epidemiological Surveillance of Infectious Diseases (NESID) Program, influenza cases from ~5,000 sentinel sites are monitored weekly as part of influenza surveillance (as number of influenza cases/sentinel site). One limitation is that the number of influenza tests conducted is not reported. Separately, the National Hospital Organization (NHO), with ~140 hospitals, routinely publishes three indicators: number of influenza tests, influenza-positive case counts, and test positivity. We used NESID and...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Takeshi Arashiro Yuzo Arima Takuri Takahashi Kiyosu Taniguchi Hiromasa Horiguchi Motoi Suzuki Source Type: research
