COVID-19 vaccine perspectives and uptake among university students three years into the pandemic
CONCLUSIONS: The majority of university students agreed that COVID-19 vaccination is important and supported COVID-19 mandates. While the rate of fully vaccinated and up-to-date students was similar to the US adult population, the latter rate needs improvement. Receipt of the BA.4/BA.5 booster was particularly low. Further education is needed to improve vaccine knowledge, especially as we move to periodic boosters. Business majors, males, and younger students may benefit from increased on-campus vaccine education initiatives.PMID:38365478 | DOI:10.1016/j.vaccine.2024.02.015 (Source: Vaccine)
Source: Vaccine - February 16, 2024 Category: Allergy & Immunology Authors: Barbara J Kuter Kate Brien Susannah Anderson Sarah Bauerle Bass Linda Gutierrez Stella Winters Breanna Eichenlaub Carmelita Whitfield Walter Faig Source Type: research
Progress of Influenza Viruses and Inhibitors
Curr Med Chem. 2024 Feb 15. doi: 10.2174/0109298673268314231204061224. Online ahead of print.ABSTRACTInfluenza is an acute respiratory disease caused by influenza viruses. It has the characteristics of fast transmission and strong infectivity, and it does great harm to human health and survival. It is estimated that the seasonal influenza epidemics every year will cause about one billion cases of infections and hundreds of thousands of deaths worldwide, while influenza A virus is the leading cause of infection and death. Currently, the main drugs used in clinics to treat influenza viruses are neuraminidase inhibitors, and ...
Source: Current Medicinal Chemistry - February 16, 2024 Category: Chemistry Authors: Yuchen Xiao Jianping Yong Shaoji Lu Canzhong Lu Ruiwen Huang Source Type: research
Social contact patterns with acquaintances and strangers related to influenza in the post-pandemic era
ConclusionsSocial contact will increase the incidence rate of influenza. Therefore, when contacting with strangers, especially in recreation places, personal protective behavior should be strengthened. (Source: Journal of Public Health)
Source: Journal of Public Health - February 16, 2024 Category: Health Management Source Type: research
U.S. COVID-19 vaccine distribution strategies, systems, performance, and lessons learned, December 2020 - May 2023
This article describes the infrastructure supporting the distribution of U.S. government-purchased COVID-19 vaccines that was in place pre-pandemic, and the infrastructure, processes, and communications efforts developed to support the heightened demands of the COVID-19 vaccination program, and describes lessons learned.PMID:38360476 | DOI:10.1016/j.vaccine.2024.02.020 (Source: Vaccine)
Source: Vaccine - February 15, 2024 Category: Allergy & Immunology Authors: Christopher Duggar Jeanne M Santoli Cameron Noblit Lori B Moore Roua El Kalach Carolyn B Bridges Source Type: research
U.S. COVID-19 vaccine distribution strategies, systems, performance, and lessons learned, December 2020 - May 2023
This article describes the infrastructure supporting the distribution of U.S. government-purchased COVID-19 vaccines that was in place pre-pandemic, and the infrastructure, processes, and communications efforts developed to support the heightened demands of the COVID-19 vaccination program, and describes lessons learned.PMID:38360476 | DOI:10.1016/j.vaccine.2024.02.020 (Source: Vaccine)
Source: Vaccine - February 15, 2024 Category: Allergy & Immunology Authors: Christopher Duggar Jeanne M Santoli Cameron Noblit Lori B Moore Roua El Kalach Carolyn B Bridges Source Type: research
Month-to-month all-cause mortality forecasting: A method allowing for changes in seasonal patterns
In this study, we propose a flexible method to forecast all-cause mortality in real-time considering short-term changes in seasonal patterns within an epidemiological year. All-cause mortality data has the advantage of being available with less delay than cause-specific mortality data. We use all-cause monthly death counts from national statistical offices for Denmark, France, Spain, and Sweden from seasons 2012/13 through 2021/22 to demonstrate the performance of the proposed approach. The method forecasts the deaths one-month-ahead, based on their expected ratio to the next month. Prediction intervals are obtained via bo...
Source: Am J Epidemiol - February 12, 2024 Category: Epidemiology Authors: Ainhoa-Elena L éger Rizzi Silvia Source Type: research
Month-to-month all-cause mortality forecasting: A method allowing for changes in seasonal patterns
In this study, we propose a flexible method to forecast all-cause mortality in real-time considering short-term changes in seasonal patterns within an epidemiological year. All-cause mortality data has the advantage of being available with less delay than cause-specific mortality data. We use all-cause monthly death counts from national statistical offices for Denmark, France, Spain, and Sweden from seasons 2012/13 through 2021/22 to demonstrate the performance of the proposed approach. The method forecasts the deaths one-month-ahead, based on their expected ratio to the next month. Prediction intervals are obtained via bo...
Source: Am J Epidemiol - February 12, 2024 Category: Epidemiology Authors: Ainhoa-Elena L éger Rizzi Silvia Source Type: research
Month-to-month all-cause mortality forecasting: A method allowing for changes in seasonal patterns
In this study, we propose a flexible method to forecast all-cause mortality in real-time considering short-term changes in seasonal patterns within an epidemiological year. All-cause mortality data has the advantage of being available with less delay than cause-specific mortality data. We use all-cause monthly death counts from national statistical offices for Denmark, France, Spain, and Sweden from seasons 2012/13 through 2021/22 to demonstrate the performance of the proposed approach. The method forecasts the deaths one-month-ahead, based on their expected ratio to the next month. Prediction intervals are obtained via bo...
Source: Am J Epidemiol - February 12, 2024 Category: Epidemiology Authors: Ainhoa-Elena L éger Rizzi Silvia Source Type: research
Month-to-month all-cause mortality forecasting: A method allowing for changes in seasonal patterns
In this study, we propose a flexible method to forecast all-cause mortality in real-time considering short-term changes in seasonal patterns within an epidemiological year. All-cause mortality data has the advantage of being available with less delay than cause-specific mortality data. We use all-cause monthly death counts from national statistical offices for Denmark, France, Spain, and Sweden from seasons 2012/13 through 2021/22 to demonstrate the performance of the proposed approach. The method forecasts the deaths one-month-ahead, based on their expected ratio to the next month. Prediction intervals are obtained via bo...
Source: Am J Epidemiol - February 12, 2024 Category: Epidemiology Authors: Ainhoa-Elena L éger Rizzi Silvia Source Type: research
Viruses, Vol. 16, Pages 285: Genetic Characterization and Phylogeographic Analysis of the First H13N6 Avian Influenza Virus Isolated from Vega Gull in South Korea
This study identified and characterized the first isolate of the H13N6 subtype from a Vega gull (Larus vegae mongolicus) in South Korea. The amino acid sequence of hemagglutinin gene showed a low pathogenic AIV subtype and various amino acid substitutions were found in the sequence compared to the reference sequence and known H13 isolates. High sequence homology with other H13N6 isolates was found in HA, NA, PB1, and PA genes, but not for PB2, NP, M, and NS genes. Interestingly, various point amino acid mutations were found on all gene segments, and some are linked to an increased binding to human-type receptors, resistanc...
Source: Viruses - February 12, 2024 Category: Virology Authors: Rochelle A. Flores Paula Leona T. Cammayo-Fletcher Binh T. Nguyen Andrea Gail M. Villavicencio Seung Yun Lee Yongwoo Son Jae-Hoon Kim Kwang Il Park Won Gi Yoo Yeung Bae Jin Wongi Min Woo H. Kim Tags: Article Source Type: research
Disparities in Influenza, Pneumococcal, COVID-19 Vaccine Coverage in High-Risk Adults 19-64 Years of Age in Southeastern Minnesota, 2010-2021
Chest. 2024 Feb 9:S0012-3692(24)00145-4. doi: 10.1016/j.chest.2024.01.049. Online ahead of print.ABSTRACTBACKGROUND: Despite effective vaccines against influenza, pneumococcus and COVID-19, uptake has been suboptimal.RESEARCH QUESTION: While disparities in vaccination by race and ethnicity have been observed, what is the role of other sociodemographic in US vaccine uptake?STUDY DESIGN AND METHODS: We conducted a population-based study using Rochester Epidemiology Project (REP), a comprehensive medical records linkage system, to assess effects of sociodemographic factors including race, ethnicity, individual-level socioecon...
Source: Chest - February 11, 2024 Category: Respiratory Medicine Authors: Jamie R Felzer Amy Montgomery Allison M LeMahieu Lila J Finney Rutten Young J Juhn Chung-Il Wi Robert M Jacobson Cassie C Kennedy Source Type: research
Influenza vaccination during the 2021/22 season: A data-linkage test-negative case-control study of effectiveness against influenza requiring emergency care in England and serological analysis of primary care patients
We present England 2021/22 end-of-season adjusted vaccine effectiveness (aVE) against laboratory confirmed influenza related emergency care use in children aged 1-17 and in adults aged 50+, and serological findings in vaccinated vs unvaccinated adults by hemagglutination inhibition assay. Influenza vaccination has been routinely offered to all children aged 2-10 years and adults aged 65 years + in England. In 2021/22, the offer was extended to children to age 15 years, and adults aged 50-64 years. Influenza activity rose during the latter half of the 2021/22 season, while remaining comparatively low due to COVID-19 pandemi...
Source: Vaccine - February 11, 2024 Category: Allergy & Immunology Authors: Heather J Whitaker Katie Hassell Katja Hoschler Linda Power Julia Stowe Nicki L Boddington Camille Tsang Hongxin Zhao Ezra Linley Elizabeth Button Cecilia Okusi Carole Aspden Rachel Byford Simon deLusignan Gayatri Amirthalingam Maria Zambon Nick J Andrews Source Type: research
Tackling Influenza A virus by M2 ion channel blockers: Latest progress and limitations
Eur J Med Chem. 2024 Feb 3;267:116172. doi: 10.1016/j.ejmech.2024.116172. Online ahead of print.ABSTRACTInfluenza outbreaks cause pandemics in millions of people. The treatment of influenza remains a challenge due to significant genetic polymorphism in the influenza virus. Also, developing vaccines to protect against seasonal and pandemic influenza infections is constantly impeded. Thus, antibiotics are the only first line of defense against antigenically distinct strains or new subtypes of influenza viruses. Among several anti-influenza targets, the M2 protein of the influenza virus performs several activities. M2 protein...
Source: European Journal of Medicinal Chemistry - February 8, 2024 Category: Chemistry Authors: Gautam Kumar Kakade Aditi Sakharam Source Type: research
Unmasking the potential of secretory IgA and its pivotal role in protection from respiratory viruses
Antiviral Res. 2024 Feb 6:105823. doi: 10.1016/j.antiviral.2024.105823. Online ahead of print.ABSTRACTMucosal immunity has regained its spotlight amidst the ongoing Coronavirus Disease 19 (COVID-19) pandemic, with numerous studies highlighting the crucial role of mucosal secretory IgA (SIgA) in protection against SARS-CoV-2 infections. The observed limitations in the efficacy of currently authorized COVID-19 vaccines in inducing effective mucosal immune responses remind us of the limitations of systemic vaccination in promoting protective mucosal immunity. This resurgence of interest has motivated the development of vaccin...
Source: Antiviral Research - February 8, 2024 Category: Virology Authors: Divya Sinha Melyssa Yaugel-Novoa Louis Waeckel St éphane Paul St éphanie Longet Source Type: research
A cost-consequence analysis of the Xpert Xpress CoV-2/Flu/RSV plus test strategy for the diagnosis of influenza-like illnesses
CONCLUSION: The Xpert Xpress CoV-2/Flu/RSV plus test allows for rapid and accurate diagnostic results, leading to reductions in testing costs and downstream healthcare resource utilization compared to other testing strategies. Compared to POC antigen testing strategies, PCR strategies were more efficient due to improved diagnostic accuracy and reduced use of confirmatory testing.PMID:38328858 | DOI:10.1080/13696998.2024.2313391 (Source: Journal of Medical Economics)
Source: Journal of Medical Economics - February 8, 2024 Category: Health Management Authors: Shawn Davies Emily Boller Jordan Chase Anne Beaubrun Cynthia Miller Ivar Jensen Source Type: research
