Am J Epidemiol; +46 new citations
46 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Epidemiol These pubmed results were generated on 2020/02/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Am J Epidemiol)
Source: Am J Epidemiol - February 12, 2020 Category: Epidemiology Tags: Report Source Type: research

Beware violated assumptions of an instrument variable fixed effects analysis.
PMID: 32025694 [PubMed - as supplied by publisher] (Source: Am J Epidemiol)
Source: Am J Epidemiol - February 5, 2020 Category: Epidemiology Authors: Blakely T, Kavanagh A, Kavanagh R, Petrie D Tags: Am J Epidemiol Source Type: research

The Authors Reply.
rino L, van Lenthe FJ, Avendano M PMID: 32025697 [PubMed - as supplied by publisher] (Source: Am J Epidemiol)
Source: Am J Epidemiol - February 5, 2020 Category: Epidemiology Authors: Authors Reply. Tags: Am J Epidemiol Source Type: research

Beta 2 agonists and the incidence of Parkinson's disease.
Abstract A recent study found a decreased risk of Parkinson's disease (PD) associated with the β2 agonist salbutamol. However, other mechanisms may explain this apparent association. Using the United Kingdom Clinical Practice Research Datalink, we formed a cohort of 2,430,884 patients aged 50 or over between 1995 and 2016. During follow-up, 8,604 cases of PD were identified and matched to 86,040 controls on sex, age, date of cohort entry, and duration of follow-up, after applying a one-year latency time window. Incidence rate ratios (RRs) of PD associated with use of β2 agonists were estimated using cond...
Source: Am J Epidemiol - February 4, 2020 Category: Epidemiology Authors: Giorgianni F, Ernst P, Dell'Aniello S, Suissa S, Renoux C Tags: Am J Epidemiol Source Type: research

Perspectives on the Future of Epidemiology: a Framework for Training.
DD Abstract Over the past century, the field of epidemiology has evolved and adapted to the changing public health needs. Challenges include newly emerging public health concerns across broad and diverse content areas, new methods, and vast data sources. We recognize the need to engage and educate the next generation of epidemiologists and prepare them to tackle these issues of the 21st century. In this commentary, we suggest a skeleton framework upon which departments of epidemiology should build their curriculum. We propose domains thatinclude: applied epidemiology, biological and social determinants of health,...
Source: Am J Epidemiol - January 31, 2020 Category: Epidemiology Authors: Lau B, Duggal P, Ehrhardt S, Armenian H, Branas CC, Colditz GA, Fox MP, Hawes SE, He J, Hofman A, Keyes K, Ko AI, Lash TL, Levy D, Lu M, Morabia A, Ness R, Nieto FJ, Schisterman EF, Stürmer T, Szklo M, Werler M, Wilcox AJ, Celentano DD Tags: Am J Epidemiol Source Type: research

Can Confidence Intervals be Interpreted?
PMID: 31994696 [PubMed - as supplied by publisher] (Source: Am J Epidemiol)
Source: Am J Epidemiol - January 29, 2020 Category: Epidemiology Authors: Naimi AI, Whitcomb BW Tags: Am J Epidemiol Source Type: research

The Association Between Unemployment and Mortality: a Cohort Study of Workplace Downsizing and Closure.
This study compared mortality for individuals unemployed from stable, downsized and closed workplaces to a reference group unexposed to unemployment. We examined nationally representative register data of residents of Finland aged 25-63 in 1990-2009 (n= 275,738). Compared to the control group, the hazard ratio for substance use-related mortality among men unemployed from stable workplaces was 2.43 (95% confidence interval [CI]: 2.22-2.67), 1.85 (CI: 1.65-2.08) from downsized workplaces and 2.16 (CI: 1.84-2.53) from closed workplaces. Among women, the corresponding estimates were 3.01 (CI: 2.42-3.74), 2.39 (CI: 1.75-3.27) a...
Source: Am J Epidemiol - January 24, 2020 Category: Epidemiology Authors: Junna L, Moustgaard H, Huttunen K, Martikainen P Tags: Am J Epidemiol Source Type: research

Smoking and Risk of Colorectal Cancer may differ by Anatomical Subsite and Sex.
Abstract The purpose of this study was to examine if the increased risk of colorectal cancer due to cigarette smoking differed by anatomical subsite and sex. We analyzed data from 188,052 participants (45% men, aged 45-75 years), who were enrolled in the Multiethnic Cohort Study in 1993-1996. During a mean follow-up of 16.7 years, we identified 4,879 incident cases of invasive colorectal adenocarcinoma. In multivariate Cox regression models, compared with never smokers of the same sex, male ever smokers had a 39% [hazard ratio (HR) =1.39; 95% Confidence interval (CI): 1.16,1.67] higher risk of left, but not of rig...
Source: Am J Epidemiol - January 23, 2020 Category: Epidemiology Authors: Gram IT, Park SY, Wilkens LR, Haiman CA, Le Marchand L Tags: Am J Epidemiol Source Type: research

Designing a Study of Correlates of Risk for Ebola Vaccination.
Abstract The rVSV Ebola vaccine was shown to be very efficacious in a novel ring vaccination trial in Guinea. However, no correlates of vaccine protection have been established for Ebola vaccines. Several Ebola vaccine candidates are available, but conducting randomized trials of additional candidates in outbreaks is difficult. Establishing correlates of vaccine protection is essential. Here we explore power and sample size calculations to evaluate potential correlates of risk during an Ebola vaccination campaignin an outbreak. The method requires a blood draw be made at a predetermined time after vaccination. The...
Source: Am J Epidemiol - January 23, 2020 Category: Epidemiology Authors: Halloran ME, Longini IM, Gilbert PB Tags: Am J Epidemiol Source Type: research

Nine-year Ethanol Intake Trajectories and Their Association With 15-year Cognitive Decline Among African-American and White Adults: The Atherosclerosis Risk in Communities Neurocognitive Study.
PMID: 31971233 [PubMed - as supplied by publisher] (Source: Am J Epidemiol)
Source: Am J Epidemiol - January 23, 2020 Category: Epidemiology Authors: Love SM, North KE, Zeng D, Petruski-Ivleva N, Kucharska-Newton A, Palta P, Graff M, Loehr L, Jones SB, Heiss G Tags: Am J Epidemiol Source Type: research

a Nationwide Case-Cohort Study.
We examined whether the use of antiasthmatic drugs was associated with the development of type 1 diabetes in childhood in a nationwide, register-based case-cohort study. We identified all children who were born 1.1.1995-31.12.2008 in Finland and diagnosed with type 1 diabetes by 2010 (n = 3,342). A 10% random sample from each birth year cohort was selected as a reference cohort (n = 80,909). Information on all dispensed antiasthmatic drugs (the Anatomical Therapeutic Chemical classification system code R03) during 1995-2009 were obtained, and the associations between the use of antiasthmatic drugs and the development of ty...
Source: Am J Epidemiol - January 23, 2020 Category: Epidemiology Authors: Metsälä J, Lundqvist A, Virta LJ, Kaila M, Gissler M, Virtanen SM, Nevalainen J Tags: Am J Epidemiol Source Type: research

Retaining Hispanics: Lessons from the Hispanic Community Health Study / Study of Latinos (HCHS/SOL).
This study aimed to examine the retention of Hispanic/Latinos participating in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), a prospective cohort study of 16,415 adults living in four US cities between 2008-2011. We summarized retention strategies and examined contact, response, and participation rates over five years of annual follow-up interviews. We then evaluated motivations for participation and satisfaction with retention efforts among participants who completed a second in-person interview approximately 6.5 years after their baseline interview. Finally, we estimated logistic regressions on associa...
Source: Am J Epidemiol - January 23, 2020 Category: Epidemiology Authors: Perreira KM, Los Angeles Abreu M, Zhao B, Youngblood ME, Alvarado C, Cobo N, Crespo-Figueroa M, Garcia ML, Giachello AL, Pattany MS, Talavera AC, Talavera GA Tags: Am J Epidemiol Source Type: research

An Innovative Prospective Hybrid Cohort-Cluster Study Design To Characterize Dengue Virus Transmission In Multigenerational Households In Kamphaeng Phet, Thailand.
Abstract Difficulties inherent in the identification of immune correlates of protection or severe disease have challenged the development and evaluation of dengue vaccines. There persist substantial gaps in knowledge about the complex effects of age and sequential dengue virus (DENV) exposures on these correlations. To address these gaps, we are conducting a novel family-based cohort-cluster study for DENV transmission in Kamphaeng Phet, Thailand. The study began in 2015 and is funded until at least 2023. As of May 2019, 2870 individuals in 485 families are actively enrolled. The families comprise at least one chi...
Source: Am J Epidemiol - January 23, 2020 Category: Epidemiology Authors: Anderson KB, Buddhari D, Srikiatkhachorn A, Ponlawat A, Gromowski GD, Iamsirithaworn S, Weg AL, Ellison DW, Macareo L, Cummings DAT, Yoon IK, Nisalak A, Thomas SJ, Fernandez S, Jarman RG, Rothman AL, Endy TP Tags: Am J Epidemiol Source Type: research

Well: What We Need to Talk About When We Talk About Health by Sandro Galea.
PMID: 31971574 [PubMed - as supplied by publisher] (Source: Am J Epidemiol)
Source: Am J Epidemiol - January 23, 2020 Category: Epidemiology Authors: Robinson LA Tags: Am J Epidemiol Source Type: research

Cohort difference in the risk of selected candidate genes on all-cause mortality at advanced ages.
Abstract Considerable efforts have been made in search of the genetic basis of human longevity but with only limited progress achieved. One important drawback of current genetic studies on human longevity is the ignorance of gene-environment interaction. Using two cohorts of long-lived individuals born in 1905 and 1915 in Denmark, we performed survival analysis to estimate risk on mortality of major candidate genes of aging and longevity and their cohort effects. Through statistical modelling that combines individual genetic and survival information with cohort-specific survival data, we estimated the relative ris...
Source: Am J Epidemiol - January 23, 2020 Category: Epidemiology Authors: Tan Q, Jacobsen R, Nygaard M, Soerensen M, Mengel-From J, Christiansen L, Christensen K Tags: Am J Epidemiol Source Type: research

Flexibly Accounting For Exposure Misclassification with External Validation Data.
Abstract Measurement error is common in epidemiology, but few studies use quantitative methods to account for bias due to mismeasurement. One barrier may be that some intuitive approaches that readily combine with methods to account for other sources of bias, like multiple imputation for measurement error (MIME), rely on internal validation data, which are rarely available. Here, we present a reparameterized imputation approach for measurement error (RIME) that can be used with internal or external validation data. We illustrate the advantages of RIME over a naïve approach that ignores measurement error and M...
Source: Am J Epidemiol - January 23, 2020 Category: Epidemiology Authors: Edwards JK, Cole SR, Fox MP Tags: Am J Epidemiol Source Type: research

JUMBO, MRFIT, and the Making of Public Health Epidemiology.
PMID: 31942923 [PubMed - as supplied by publisher] (Source: Am J Epidemiol)
Source: Am J Epidemiol - January 15, 2020 Category: Epidemiology Authors: Morabia A Tags: Am J Epidemiol Source Type: research

Invited commentary: Adult child US migration status and cognitive decline among older parents who remain in Mexico - a new perspective on loneliness and social isolation.
Abstract There is a growing body of research on the link between social isolation, loneliness and health outcomes in later life, including cognitive decline and dementia. In the current issue of the Journal, Torres et al (Am J Epidemiol) have studied the association between adult child migration status and cognitive performance in parents staying behind in Mexico, using longitudinal data from the Mexican Health and Aging Study. This is an excellent example of the role that emotional and social factors may play in the development of cognitive impairment among older adults. In their study, having an adult child in t...
Source: Am J Epidemiol - January 13, 2020 Category: Epidemiology Authors: Holwerda TJ, Hoogendijk EO Tags: Am J Epidemiol Source Type: research

Galaxy Plot: A New Visualization Tool of Bivariate Meta-Analysis Studies.
Abstract Funnel plots have been widely used to detect small study effects in the results of univariate meta-analyses. However, there is no existing visualization tool that is the counterpart of the funnel plot in the multivariate setting. We propose a new visualization method, the galaxy plot, which can simultaneously present the effect sizes of bivariate outcomes and their standard errors in a two-dimensional space. We illustrate the use of galaxy plot by two case studies, including a meta-analysis of hypertension trials with studies from 1979 to 1991, and a meta-analysis of structured telephone support or non-in...
Source: Am J Epidemiol - January 13, 2020 Category: Epidemiology Authors: Hong C, Duan R, Zeng L, Hubbard RA, Lumley T, Riley R, Chu H, Kimmel SE, Chen Y Tags: Am J Epidemiol Source Type: research

Adult Child US Migration Status and Cognitive Decline Among Older Parents Who Remain in Mexico.
Abstract Low and middle-income countries (LMICs) are experiencing rapid aging, growing dementia burden, and relatively high rates of out-migration among working age adults. Family-member migration status may be a unique societal determinant of cognitive aging in LMIC settings. We aimed to evaluate the effect of adult child United States migration status on change in cognitive performance scores using data from the Mexican Health and Aging Study, a population-based, national-level cohort of adults in Mexico> 50 years old at baseline (2001), with 2, 11, and 14-year follow-up waves (2003, 2012, 2015). 5972 and 493...
Source: Am J Epidemiol - January 13, 2020 Category: Epidemiology Authors: Torres JM, Sofrygin O, Rudolph KE, Haan MN, Wong R, Glymour MM Tags: Am J Epidemiol Source Type: research

Characterizing Cross-Culturally Relevant Metrics of Stigma among Men who have Sex with Men across Eight Sub-Saharan African Countries and the United States.
This study explored the underlying factor structure and psychometric properties of 13 sexual behavior stigma items among 10,396 MSM across eight sub-Saharan African countries and the United States (U.S.) using cross-sectional data collected between 2012 and 2016. Exploratory factor analyses were used to examine the number and composition of underlying stigma factors. A three-factor model was found to be an adequate fit in all countries (Root Mean Square Error of Approximation = 0.02-0.05; Comparative Fit Index/Tucker Lewis Index = 0.97-1.00/0.94-1.00; Standardized Root Mean Square Residual = 0.04-0.08), consisting of "...
Source: Am J Epidemiol - January 13, 2020 Category: Epidemiology Authors: Augustinavicius JL, Baral SD, Murray SM, Jackman K, Xue QL, Sanchez TH, Nowak RG, Crowell TA, Zlotorzynska M, Olawore O, Lyons CE, Njindam IM, Tamoufe U, Diouf D, Drame F, Kouanda S, Kouame A, Charurat ME, Anato S, Mothopeng T, Mnisi Z, Kane JC Tags: Am J Epidemiol Source Type: research

Using Evidence Factors to Clarify Exposure Biomarkers.
Abstract A study has two evidence factors if it permits two statistically independent inferences about one treatment effect such that each factor is immune to some bias that would invalidate the other factor. Because the two factors are statistically independent, the evidence they provide may be combined using methods associated with meta-analysis for independent studies, despite using the same data twice in different ways. We illustrate evidence factors, applying them in a new way in investigations that have both an exposure biomarker and a coarse external measure of exposure to a treatment. To illustrate, we con...
Source: Am J Epidemiol - January 8, 2020 Category: Epidemiology Authors: Karmakar B, Small DS, Rosenbaum PR Tags: Am J Epidemiol Source Type: research

PTC1 and PTC2: New Indices of Blood Pressure Waveforms and Cardiovascular Disease.
Abstract Systolic and diastolic blood pressures provide information about cardiovascular disease (CVD) but are only extremes of the pressure waveform during the cardiac cycle. We developed summaries of the pressure decay, PTC1 and PTC2, that are related to arterial compliance and to an existing proprietary summary which has been shown to predict CVD. We derived the summaries from a Windkessel model (consisting of a decaying exponential plus a dampened cosine, and an intercept so they are independent of calibration with blood pressure, unlike the proprietary measures), and estimated them using nonlinear least squar...
Source: Am J Epidemiol - January 7, 2020 Category: Epidemiology Authors: Brumback LC, Jacobs DR, Duprez DA Tags: Am J Epidemiol Source Type: research

Assessing Representation and Perceived Inclusion among Members in the Society for Epidemiologic Research.
Abstract Using web-based survey data collected June - August 2018 from the Society for Epidemiologic Research (SER) members, we characterized numerous dimensions of social identity and lived experience, and assessed relationships between these characteristics and perceptions of inclusion and society participation. We quantified associations between characteristics, feeling very welcomed, high (top 25th percentile) self-initiated participation, and any (top 10th percentile) society-initiated participation. Racial/ethnic and religious minority categories were blinded to preserve anonymity and we accounted for missin...
Source: Am J Epidemiol - January 7, 2020 Category: Epidemiology Authors: DeVilbiss EA, Weuve J, Fink DS, Morris MD, Arah OA, Radoc JG, Datta GD, Abuelezam NN, Lopez DS, Johnson DA, Branas CC, Schisterman EF Tags: Am J Epidemiol Source Type: research

Childbearing is Associated with a Short-term Reduced Risk of Crohn's Disease in Mothers.
ash;ivik ML Abstract The aim was to analyse the importance of childbearing for inflammatory bowel disease risks. Using data from the Norwegian Population Register and the Norwegian Patient Register, discrete-time hazard models for diagnosis of Crohn's disease (CD) or ulcerative colitis (UC) were estimated for men and women of age 18-81 in 2011-2016. Year and various socio-demographic factors were controlled for. The data included 4304 CD and 8866 UC cases. Women whose youngest child was 0-4 years old had lower CD risk the following year than the childless (OR 0.73, CI: 0.62, 0.86). There was no such reduction in C...
Source: Am J Epidemiol - January 7, 2020 Category: Epidemiology Authors: Kravdal Ø, Magnus P, Moum B, Høivik ML Tags: Am J Epidemiol Source Type: research

Neighborhood Privilege, Preterm Delivery, and Related Racial/Ethnic Disparities: An Intergenerational Application of the Index of Concentration at the Extremes.
Abstract Neighborhood conditions are linked to preterm delivery and related racial/ethnic disparities. We assessed whether early childhood and adulthood experiences of neighborhood privilege, measured by the Index of Concentration at the Extremes (ICE), were associated with preterm delivery and related disparities using intergenerationally linked birth records of 379,794 California-born primiparous mothers (born 1982-1997) and their infants (born 1997-2011). ICE measures during early childhood and adulthood approximated racial/ethnic and economic dimensions of neighborhood privilege and disadvantage separately (IC...
Source: Am J Epidemiol - January 7, 2020 Category: Epidemiology Authors: Shrimali BP, Pearl M, Karasek D, Reid C, Abrams B, Mujahid M Tags: Am J Epidemiol Source Type: research

Long-Term Exposure to Ambient Fine Particulate Matter and Mortality from Renal Failure: A Retrospective Cohort Study in Hong Kong.
Abstract Numerous studies have indicated the ambient particulate matter is closely associated with increased cardiovascular disease, yet the evidence for its association with the renal disease remains under-recognized. We aimed to estimate the association between long-term exposure to fine particulate matter (PM2.5) and renal failure (RF) mortality among participants of the Elderly Health Service Cohort in Hong Kong from 1998 to 2010. PM2.5 concentration at the residential address of each participant was estimated based on a satellite-based spatiotemporal model. We used Cox proportional hazards regression to estim...
Source: Am J Epidemiol - January 6, 2020 Category: Epidemiology Authors: Ran J, Yang A, Sun S, Han L, Li J, Guo F, Zhao S, Yang Y, Mason TG, Chan KP, Lee RS, Qiu H, Tian L Tags: Am J Epidemiol Source Type: research

Early Educational Experiences and Trajectories of Cognitive Functioning Among Mid-Life and Older U.S. Adults.
Abstract Educational attainment is often considered the most important protective factor against cognitive impairment and dementia, yet significant variation in early educational experiences exists among mid-life and older U.S. adults. We use prospective data from the Health and Retirement Study (HRS) along with information on respondents' early educational experiences collected in the 2015 and 2017 HRS Life History Mail Survey (HRS-LHMS) to examine if school context, educational content, and academic ability are associated with trajectories of cognitive functioning and whether educational attainment explains this...
Source: Am J Epidemiol - January 6, 2020 Category: Epidemiology Authors: Walsemann KM, Ailshire JA Tags: Am J Epidemiol Source Type: research

Social Support and Positive Coping Skills Act as Mediators Buffering the Impact of Childhood Maltreatment on Psychological Distress and Positive Mental Health in Adulthood: Analysis of a National Population-Based Sample.
Abstract There is little research on how childhood maltreatment influences the use of resilience mechanisms that are key to mental health outcomes in the face of adversity. We assessed the mediating roles of social support and positive coping skills in the relationships between childhood maltreatment and both psychological distress and positive mental health. Data analyzed were from a national population survey-the 2012 Canadian Community Health Survey-Mental Health (CCHS-MH 2012, N=25,113). Confirmatory factor analysis and structural equation modeling were used to model the relationships between childhood maltrea...
Source: Am J Epidemiol - January 6, 2020 Category: Epidemiology Authors: Su Y, D'Arcy C, Meng X Tags: Am J Epidemiol Source Type: research

Adaptive Treatment Strategies with Survival Outcomes: An Application to the Treatment of Type 2 Diabetes using a Large Observational Database.
Abstract Sequences of treatments that adapt to a patient's changing condition over time are often needed for the management of chronic diseases. An adaptive treatment strategy (ATS) consists of personalized treatment rules to be applied through the course of a disease that input the patient's characteristics at the time of decision-making and output a recommended treatment. An optimal ATS is the sequence of tailored treatments that yields the best clinical outcome for patients sharing similar characteristics. Methods to estimate optimal adaptive treatment strategies, which must disentangle short- and long-term tre...
Source: Am J Epidemiol - January 3, 2020 Category: Epidemiology Authors: Simoneau G, Moodie EEM, Azoulay L, Platt RW Tags: Am J Epidemiol Source Type: research

Hospital Records of Pain, Fatigue, or Circulatory Symptoms in Girls Exposed to Human Papillomavirus Vaccination: Cohort, Self-controlled Case Series, and Population Time Trend Studies.
This study with nationwide coverage showed no evidence of a causal link between HPV vaccination and diffuse autonomic symptoms leading to hospital contact. PMID: 31899791 [PubMed - as supplied by publisher] (Source: Am J Epidemiol)
Source: Am J Epidemiol - January 3, 2020 Category: Epidemiology Authors: Thomsen RW, Öztürk B, Pedersen L, Nicolaisen SK, Petersen I, Olsen J, Sørensen HT Tags: Am J Epidemiol Source Type: research

Gastric Atrophy and its Interaction with Poor Oral Health Elevate the Risk for Esophageal Squamous Cell Carcinoma in a High-risk Region of China: a Population-based Case-control Study.
Abstract Previous findings concerning gastric atrophy as a potential risk factor for esophageal squamous cell carcinoma (ESCC) have been inconsistent. Our aim was to test whether gastric atrophy, and further its interaction with poor oral health, elevate the risk for ESCC in a high-risk region of China. Our population-based case-control study in Taixing, China from 2010-2014, recruited cases from local hospitals and the local cancer registry. Controls were selected randomly from the local population registry. Ultimately, 1210 cases and 1978 controls answered questionnaire and provided blood samples for assay of pe...
Source: Am J Epidemiol - January 3, 2020 Category: Epidemiology Authors: Ekheden I, Yang X, Chen H, Chen X, Yuan Z, Jin L, Lu M, Ye W Tags: Am J Epidemiol Source Type: research

Am J Epidemiol; +35 new citations
35 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Epidemiol These pubmed results were generated on 2019/12/25PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Am J Epidemiol)
Source: Am J Epidemiol - December 25, 2019 Category: Epidemiology Tags: Report Source Type: research

Evaluating the Utility of Coarsened Exact Matching for Pharmacoepidemiology using Real and Simulated Claims Data.
Abstract Coarsened exact matching (CEM) is a matching method proposed as an alternative to other techniques commonly used to control confounding. We compared CEM with 3 techniques that have been used in pharmacoepidemiology: propensity score matching, Mahalanobis distance matching and fine stratification by propensity score (FS). We evaluated confounding control and effect estimate precision using insurance claims data from the Pharmaceutical Assistance Contract for the Elderly (1999-2002) and Medicaid Analytic eXtract (2000-2007) databases (United States), and from simulated claims-based cohorts. CEM generally ac...
Source: Am J Epidemiol - December 17, 2019 Category: Epidemiology Authors: Ripollone JE, Huybrechts KF, Rothman KJ, Ferguson RE, Franklin JM Tags: Am J Epidemiol Source Type: research

Women's reproductive lifespan and subsequent inflammatory profile, how to best measure reproductive lifespan and the need for baseline assessments.
Abstract Inflammatory processes are known to drive the pathogenesis of several chronic diseases, including cardiovascular disease, Alzheimer's disease, and all-cause mortality. Emerging research indicates that women who have a longer reproductive lifespan, roughly age of menarche to age of menopause or lifetime ovulatory cycles after accounting for anovulatory timespans, are at lower risk for these same inflammation-related chronic diseases. The paradox is that ovulation is known to induce acute inflammation. Given the limited research that has assessed the relationship between reproductive lifespan and later infl...
Source: Am J Epidemiol - December 17, 2019 Category: Epidemiology Authors: Schliep KC Tags: Am J Epidemiol Source Type: research

Organophosphate Pesticide Exposures and Menstrual Cycle Characteristics in Chinese Preconception Women.
Abstract Organophosphates (OPs) are the most heavily used pesticides in China. The Chinese population, including preconception women, is highly exposed. Yet, little is known regarding the associations of OPs on menstruation in humans. We conducted a cross-sectional analysis in women preparing for pregnancy to investigate the relationship between biomarkers of OP exposure and menstrual cycle characteristics. From 2013 to 2015, 627 women attended free preconception care clinics at two maternity hospitals in Shanghai were included. Information on menstrual cycle characteristics was obtained through questionnaires. OP...
Source: Am J Epidemiol - December 17, 2019 Category: Epidemiology Authors: Zhang Y, Ji L, Hu Y, Tse LA, Wang Y, Qin K, Ding G, Zhou Y, Yu X, Ouyang F, Zhang J, Gao Y, Tian Y, Shanghai Birth Cohort Study Tags: Am J Epidemiol Source Type: research

Learning from Our Past to Build on Our Future: Lessons Learned from MRFIT and "JUMBO".
Learning from Our Past to Build on Our Future: Lessons Learned from MRFIT and "JUMBO". Am J Epidemiol. 2019 Dec 17;: Authors: Odoms-Young A, Thorpe RJ Abstract In this invited commentary, we propose that Blackburn (XXXX) ignores several important issues that need to be considered in the context of a historic reflection of MRFIT and JUMBO. A key focus of this commentary is to offer an alternative perspective on both studies using our current understanding of the impact of social and structural determinants of health, evidence that policy, systems, and environmental interventions are needed to...
Source: Am J Epidemiol - December 17, 2019 Category: Epidemiology Authors: Odoms-Young A, Thorpe RJ Tags: Am J Epidemiol Source Type: research

Response to Commentaries by Schildkraut and Schliep.
PMID: 31845727 [PubMed - as supplied by publisher] (Source: Am J Epidemiol)
Source: Am J Epidemiol - December 17, 2019 Category: Epidemiology Authors: Huang T, Shafrir AL, Eliassen AH, Rexrode KM, Tworoger SS Tags: Am J Epidemiol Source Type: research

Estimated Lifetime Ovulatory Years and Its Determinants in Relation to Circulating Inflammatory Biomarkers.
Abstract Reproductive events, such as ovulation, trigger an inflammatory cascade. Few studies have examined their long-term influence on inflammatory profiles. We included 3,393 premenopausal and 3,915 postmenopausal women with intact ovaries/uterus from the Nurses' Health Studies, and estimated lifetime ovulatory years (LOY) as age at menopause (age at blood collection for premenopausal women) minus age at menarche, years of oral contraceptive (OC) use, and one year per pregnancy. After adjusting for other inflammation-related factors (e.g., BMI, exercise, diet, etc.), every 5-year increase in LOY was associated ...
Source: Am J Epidemiol - December 17, 2019 Category: Epidemiology Authors: Huang T, Shafrir AL, Eliassen AH, Rexrode KM, Tworoger SS Tags: Am J Epidemiol Source Type: research

Commentary: Estimated Lifetime Ovulatory Years and Its Determinants in Relation to Circulating Inflammatory Markers.
Abstract In this issue of the American Journal of Epidemiology, Huang et al. report an inverse relationship between lifetime ovulatory cycle years (LOY) and circulating C-reactive protein (CRP), counter to their hypothesis. CRP is a non-specific systemic marker of chronic inflammation and there is evidence that there are other drivers of systemic inflammation as measured by CRP. There also is a body of evidence supporting that ovulation may be responsible for a localized inflammatory response. As ovarian cancer is the fifth most common cause of cancer death in women, preventive strategies are urgently needed. The ...
Source: Am J Epidemiol - December 17, 2019 Category: Epidemiology Authors: Schildkraut JM Tags: Am J Epidemiol Source Type: research

Head and Neck Cancer Risk Prediction Models for the US Population from the INHANCE Consortium.
Boffetta P, Hashibe M Abstract Head and neck cancer (HNC) risk prediction models based on risk factor profiles have not yet been developed. We took advantage of the large database including 14 studies (1981-2010) in the US from the International Head and Neck Cancer Epidemiology (INHANCE) Consortium to develop risk prediction models. Seventy percent of the data were used to develop HNC risk prediction models; the remaining 30% were used to validate the models. We used competing risk models to calculate absolute risks. The predictors included age, sex, education, race/ethnicity, alcohol drinking intensity, cigarett...
Source: Am J Epidemiol - November 29, 2019 Category: Epidemiology Authors: Lee YA, Al-Temimi M, Ying J, Muscat J, Olshan AF, Zevallos JP, Winn DM, Li G, Sturgis EM, Morgenstern H, Zhang ZF, Smith E, Kelsey K, McClean M, Vaughan TL, Lazarus P, Chen C, Schwartz SM, Gillison M, Schantz S, Yu GP, D'Souza G, Gross N, Monroe M, Kim J, Tags: Am J Epidemiol Source Type: research

Observational Study of the Association between Participation in High School Football and Self-Rated Health, Obesity, and Pain in Adulthood.
In conclusion, our findings suggest that playing football in high school was not significantly associated with poor or fair self-related health at the age of 65 but was associated with the risk of being obese as an adult compared to not playing football in high school. Our findings provide needed information about the risk of playing football to broader set of health outcomes. PMID: 31781744 [PubMed - as supplied by publisher] (Source: Am J Epidemiol)
Source: Am J Epidemiol - November 29, 2019 Category: Epidemiology Authors: Gaulton TG, Deshpande SK, Small DS, Neuman MD Tags: Am J Epidemiol Source Type: research

Long-Term Trajectories of Body Weight, Diet, and Physical Activity From Midlife Through Late-Life and Subsequent Cognitive Decline in Women.
In conclusion, maintaining healthy lifestyle since midlife may help reduce cognitive decline in aging. At older ages, both deceleration of weight gain and decrease in physical activity may reflect early signs of cognitive impairment. PMID: 31781745 [PubMed - as supplied by publisher] (Source: Am J Epidemiol)
Source: Am J Epidemiol - November 29, 2019 Category: Epidemiology Authors: Wagner M, Grodstein F, Proust-Lima C, Samieri C Tags: Am J Epidemiol Source Type: research

Evaluation of the Normality Assumption in Meta-analyses.
We present a standardization framework for evaluation of the normality assumption and examine its performance in random-effects meta-analyses with simulation studies and real examples. We use both a formal statistical test and a quantile-quantile plot for visualization. Simulation studies show that our normality test has well-controlled type I error rates and reasonable power. We also illustrate the real-world significance of examining the normality assumption with examples. Investigating the normality assumption can provide valuable information for further analysis or clinical application. We recommend routine examination...
Source: Am J Epidemiol - November 29, 2019 Category: Epidemiology Authors: Wang CC, Lee WC Tags: Am J Epidemiol Source Type: research

Am J Epidemiol; +52 new citations
52 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Epidemiol These pubmed results were generated on 2019/11/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Am J Epidemiol)
Source: Am J Epidemiol - November 20, 2019 Category: Epidemiology Tags: Report Source Type: research

The Dynamic Relationship between Asthma and Obesity in School Children.
In conclusion, childhood asthma drives an increase in the onset of obesity among school children, while the onset of obesity does not necessarily imply the future onset of asthma at least in the short term. PMID: 31712801 [PubMed - as supplied by publisher] (Source: Am J Epidemiol)
Source: Am J Epidemiol - November 12, 2019 Category: Epidemiology Authors: Zhang Y, Chen Z, Berhane K, Urman R, Chatzi VL, Breton C, Gilliland FD Tags: Am J Epidemiol Source Type: research

A Randomized Trial to Evaluate the Effects of Folic Acid and Zinc Supplementation on Male Fertility and Live Birth: Design and Baseline Characteristics.
Abstract The Folic Acid and Zinc Supplementation Trial (FAZST) was a multi-center, double-blind, block-randomized, placebo-controlled trial to determine whether folic acid and zinc supplementation in men improves semen quality and increases live birth rate among couples seeking infertility treatment (2013-2017). Eligible men were ages 18 years or older with their female partners ages 18-45 seeking infertility treatment. Men were randomized (1:1) to 5 mg folic acid and 30 mg elemental zinc daily or matching placebo for six months. Randomization was stratified by site and intended infertility treatment (in vitro fer...
Source: Am J Epidemiol - November 12, 2019 Category: Epidemiology Authors: Schisterman EF, Clemons T, Peterson CM, Johnstone E, Hammoud AO, Lamb D, Carrell DT, Perkins NJ, Sjaarda LA, Van Voorhis BJ, Ryan G, Summers K, Campbell B, Robins J, Chaney K, Mills JL, Mendola P, Chen Z, DeVilbiss EA, Mumford SL Tags: Am J Epidemiol Source Type: research

Association of Infection with Chronic Hepatitis C Virus and Myocardial Infarction in People Living with HIV in the United States.
We examined the association between HCV and MI in the Centers for Acquired Immunodeficiency Syndrome Research Network of Integrated Clinical Systems, a multi-center clinical cohort of PLWH. MIs were centrally adjudicated and categorized by type using the Universal MI definition. We estimated the association between chronic HCV (RNA+) and time to MI adjusting for demographic characteristics, cardiovascular risk factors, clinical characteristics and history of injecting drug use. Among 23,407 PLWH aged ≥18, there were 336 T1MI and 330 T2MI during a median of 4.7 years of follow-up during 1998 through 2016. HCV was associa...
Source: Am J Epidemiol - November 12, 2019 Category: Epidemiology Authors: Williams-Nguyen J, Hawes SE, Nance RM, Lindström S, Heckbert SR, Kim HN, Mathews WC, Cachay ER, Budoff M, Hurt CB, Hunt PW, Geng E, Moore RD, Mugavero MJ, Peter I, Kitahata MM, Saag MS, Crane HM, Delaney JA Tags: Am J Epidemiol Source Type: research

Re: Religion as a social determinant of health.
PMID: 31712808 [PubMed - as supplied by publisher] (Source: Am J Epidemiol)
Source: Am J Epidemiol - November 12, 2019 Category: Epidemiology Authors: VanderWeele TJ, Chen Y Tags: Am J Epidemiol Source Type: research

Pre-Pregnancy Diabetes and Perinatal Mental Illness: A Population-Based Latent Class Analysis.
We examined the risk of any perinatal mental illness associated with pre-pregnancy diabetes and identified how diabetes duration, complexity, and intensity of care affect this risk. We performed a population-based study of 15 to 49-year-old women with (n=14,186) and without (n=843,818) pre-pregnancy diabetes who had a singleton livebirth (Ontario, Canada, 2005-2015) and no recent mental illness. Modified Poisson regression estimated perinatal mental illness risk between conception and 1 year postpartum in women with vs. without diabetes and in diabetes groups, defined by a latent class analysis of diabetes duration, comple...
Source: Am J Epidemiol - November 12, 2019 Category: Epidemiology Authors: Brown HK, Cairncross ZF, Lipscombe LL, Wilton AS, Dennis CL, Ray JG, Guttmann A, Vigod SN Tags: Am J Epidemiol Source Type: research