Interaction and antiviral treatment of coinfection between SARS-CoV-2 and influenza in vitro
CONCLUSIONS: In coinfection, the replication of SARS-CoV-2 would be interfered by influenza H1N1. Compared with molnupiravir or baloxavir monotherapy, treatment with a combination of molnupiravir and baloxavir should be considered for early treatment in patients with SARS-CoV-2 and influenza coinfection.PMID:38621598 | DOI:10.1016/j.virusres.2024.199371 (Source: Virus Research)
Source: Virus Research - April 15, 2024 Category: Virology Authors: Danlei Liu Ka-Yi Leung Hoi-Yan Lam Ruiqi Zhang Yujing Fan Xiaochun Xie Kwok-Hung Chan Ivan Fan-Ngai Hung Source Type: research

SARS-CoV-2 and influenza virus coinfections in the Tuscan population during the 2021/2022 influenza season
The 2021/2022 influenza season was not characterised by a well-defined incidence peak. As reported by the Italian National Institute of Health, a high value of incidence of influenza cases was recorded in week 13, but it was still lower than in other influenza seasons. This abnormal circulation was probably due to relaxation of the COVID-19 pandemic restriction measures, which greatly reduced the circulation of respiratory-transmitted viruses, including human respiratory syncytial virus (HRSV). The symptoms of SARS-CoV-2 and influenza are quite similar, sharing the human-to-human transmission route via respiratory droplets...
Source: Journal of Preventive Medicine and Hygiene - April 15, 2024 Category: International Medicine & Public Health Authors: Ilaria Manini, Giovanna Milano, Serena Marchi, Ilaria Vicenti, Camilla Biba, Lia Fiaschi, Claudia Maria Trombetta, Giacomo Lazzeri, Emanuele Montomoli Source Type: research

Avian ‘Bird’ Flu – undue media panic or genuine concern for pandemic potential requiring global preparedness action?
epidemics, avian influenza, H5N1, highly pathogenic avian influenza, HPAI (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - April 15, 2024 Category: Infectious Diseases Authors: Eskild Petersen, Ziad A Memish, David S Hui, Alessandra Scagliarini, Lone Simonsen, Edgar Simulundu, Jennifer Bloodgood, Lucille Blumberg, Shui- Shan Lee, Alimuddin Zumla Tags: Editorial Source Type: research

Is HealthPathways viewed as a useful and trustworthy source of information by health professionals?
ConclusionsHealthPathways is viewed as a useful and trusted source of information for health professionals in the North Coast NSW region. HealthPathways provides an opportunity for timely dissemination of information during critical events, including natural disasters and emergencies.PMID:38616105 | DOI:10.1071/AH23107 (Source: Australian Health Review)
Source: Australian Health Review - April 14, 2024 Category: Hospital Management Authors: Rebecca Tretheway Victoria Visser Sarah Mollard Source Type: research

Is HealthPathways viewed as a useful and trustworthy source of information by health professionals?
ConclusionsHealthPathways is viewed as a useful and trusted source of information for health professionals in the North Coast NSW region. HealthPathways provides an opportunity for timely dissemination of information during critical events, including natural disasters and emergencies.PMID:38616105 | DOI:10.1071/AH23107 (Source: Australian Health Review)
Source: Australian Health Review - April 14, 2024 Category: Hospital Management Authors: Rebecca Tretheway Victoria Visser Sarah Mollard Source Type: research

Is HealthPathways viewed as a useful and trustworthy source of information by health professionals?
ConclusionsHealthPathways is viewed as a useful and trusted source of information for health professionals in the North Coast NSW region. HealthPathways provides an opportunity for timely dissemination of information during critical events, including natural disasters and emergencies.PMID:38616105 | DOI:10.1071/AH23107 (Source: Australian Health Review)
Source: Australian Health Review - April 14, 2024 Category: Hospital Management Authors: Rebecca Tretheway Victoria Visser Sarah Mollard Source Type: research

Is HealthPathways viewed as a useful and trustworthy source of information by health professionals?
ConclusionsHealthPathways is viewed as a useful and trusted source of information for health professionals in the North Coast NSW region. HealthPathways provides an opportunity for timely dissemination of information during critical events, including natural disasters and emergencies.PMID:38616105 | DOI:10.1071/AH23107 (Source: Australian Health Review)
Source: Australian Health Review - April 14, 2024 Category: Hospital Management Authors: Rebecca Tretheway Victoria Visser Sarah Mollard Source Type: research

Post-pandemic trends: Epidemiological and etiological insights into acute respiratory infections in southern China
This study provides valuable insights into the dynamic nature of respiratory pathogens post COVID-19 era.PMID:38598951 | DOI:10.1016/j.diagmicrobio.2024.116293 (Source: Adv Data)
Source: Adv Data - April 10, 2024 Category: Epidemiology Authors: Yuquan Gao Xudong Feng Ting Yuan Min Li Muyun Wei Shuangshuang Li Source Type: research

Generation and characterization of a nanobody against the avian influenza virus H7 subtype
This study screened a strain of Nb with high hemagglutination inhibition activity and enhanced its antiviral activity through oligomerization, which may have great potential for developing effective agents for the prevention, diagnosis, and treatment of AIV H7 subtype infection.PMID:38593899 | DOI:10.1016/j.ijbiomac.2024.131458 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 9, 2024 Category: Biochemistry Authors: Xiuqin Huang Weiye Li Xuewei Cao Qi Zhang Yizhen Lin Siqi Xu Xinying Dong Peiqi Liu Yutong Liu Ge He Kaijian Luo Saixiang Feng Source Type: research

A comparative analysis of knowledge, attitude, and practice (KAP) towards influenza and influenza vaccination among healthcare workers in Kyrgyzstan prior to and during the COVID-19 pandemic
CONCLUSION: Our investigation provides valuable insights into HCWs KAP concerning influenza vaccination in Kyrgyzstan, highlighting the need for targeted interventions addressing factors influencing vaccine acceptance. The study suggests policy implications, advocating for the revision of national strategies to strengthen capacity building for medical staff.PMID:38594119 | DOI:10.1016/j.vaccine.2024.04.008 (Source: Vaccine)
Source: Vaccine - April 9, 2024 Category: Allergy & Immunology Authors: Rakhat Akmatova Malembe S Ebama Sanjar Temirbekov Venera Alymkulova Dinara Otorbaeva Source Type: research

Generation and characterization of a nanobody against the avian influenza virus H7 subtype
This study screened a strain of Nb with high hemagglutination inhibition activity and enhanced its antiviral activity through oligomerization, which may have great potential for developing effective agents for the prevention, diagnosis, and treatment of AIV H7 subtype infection.PMID:38593899 | DOI:10.1016/j.ijbiomac.2024.131458 (Source: International Journal of Biological Macromolecules)
Source: International Journal of Biological Macromolecules - April 9, 2024 Category: Biochemistry Authors: Xiuqin Huang Weiye Li Xuewei Cao Qi Zhang Yizhen Lin Siqi Xu Xinying Dong Peiqi Liu Yutong Liu Ge He Kaijian Luo Saixiang Feng Source Type: research

A comparative analysis of knowledge, attitude, and practice (KAP) towards influenza and influenza vaccination among healthcare workers in Kyrgyzstan prior to and during the COVID-19 pandemic
CONCLUSION: Our investigation provides valuable insights into HCWs KAP concerning influenza vaccination in Kyrgyzstan, highlighting the need for targeted interventions addressing factors influencing vaccine acceptance. The study suggests policy implications, advocating for the revision of national strategies to strengthen capacity building for medical staff.PMID:38594119 | DOI:10.1016/j.vaccine.2024.04.008 (Source: Vaccine)
Source: Vaccine - April 9, 2024 Category: Allergy & Immunology Authors: Rakhat Akmatova Malembe S Ebama Sanjar Temirbekov Venera Alymkulova Dinara Otorbaeva Source Type: research

Avian Influenza A (H5N1) Outbreak 2024 in Cambodia: Worries Over the Possible Spread of the Virus to Other Asian Nations and the Strategic Outlook for its Control
Environ Health Insights. 2024 Apr 6;18:11786302241246453. doi: 10.1177/11786302241246453. eCollection 2024.ABSTRACTAsia has been alarmed by the resurgence of avian influenza A (H5N1) in Cambodia in 2024. H5N1 could be swiftly transmitted by wild birds to poultry populations along their migration route via infection. Circulation of endemic H5N1 in Asian poultry facilitates recurrent human transmission. Cambodia's role as a reservoir heightens the potential dangers of uncoordinated containment and surveillance across Southeast Asia. This correspondence addresses the risk factors, seasonal patterns, transmission dynamics, and...
Source: Environmental Health Insights - April 8, 2024 Category: Environmental Health Authors: Farhana Yesmin Nidra Mayesha Bintey Monir Syed Masudur Rahman Dewan Source Type: research

COVID-19 critical care triage across Canada: a narrative synthesis and ethical analysis of early provincial triage protocols
CONCLUSIONS: Early provincial COVID-19 triage protocols were developed by dedicated expert committees under challenging circumstances. Nonetheless, few were publicly available, and public consultation was limited. No protocols were ever implemented, including during periods of extreme critical care surge. A national approach to pandemic triage that incorporates additional aspects of procedural justice should be considered in preparation for future pandemics.PMID:38589739 | DOI:10.1007/s12630-024-02744-y (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - April 8, 2024 Category: Anesthesiology Authors: Sarah K Andersen Nathan Gamble Oleksa Rewa Source Type: research

Exploring viral aetiology in upper respiratory tract infections: insights from metagenomic next-generation sequencing in Swiss outpatients before and during the SARS-CoV-2 pandemic
CONCLUSIONS: Viral mNGS allowed the initial diagnosis to be retrospectively re-evaluated. Assuming reduced turnaround times, mNGS has the potential to directly guide the treatment of upper respiratory tract infections. On an epidemiological level, our study highlights the utility of mNGS in respiratory infection surveillance, allowing early detection of epidemics and providing information crucial for prevention.PMID:38587784 | DOI:10.57187/s.3797 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 8, 2024 Category: General Medicine Authors: Verena Kufner Andrea C Frey Sara H Burkhard Stefan Schmutz Gabriela Ziltener Maryam Zaheri Caroline V Wiedmer Andreas Plate Alexandra Trkola Michael Huber Nicolas J Mueller Source Type: research