Recent Changes in Patterns of Mammal Infection with Highly Pathogenic Avian Influenza A(H5N1) Virus Worldwide
Emerg Infect Dis. 2024 Mar;30(3):444-452. doi: 10.3201/eid3003.231098.ABSTRACTWe reviewed information about mammals naturally infected by highly pathogenic avian influenza A virus subtype H5N1 during 2 periods: the current panzootic (2020-2023) and previous waves of infection (2003-2019). In the current panzootic, 26 countries have reported >48 mammal species infected by H5N1 virus; in some cases, the virus has affected thousands of individual animals. The geographic area and the number of species affected by the current event are considerably larger than in previous waves of infection. The most plausible source of mamm...
Source: Emerging Infectious Diseases - February 26, 2024 Category: Infectious Diseases Authors: Pablo I Plaza V íctor Gamarra-Toledo Juan Rodr íguez Euguí Sergio A Lambertucci Source Type: research
Highly Pathogenic Avian Influenza A(H5N1) Virus Clade 2.3.4.4b in Domestic Ducks, Indonesia, 2022
Emerg Infect Dis. 2024 Mar;30(3):586-590. doi: 10.3201/eid3003.230973.ABSTRACTHighly pathogenic avian influenza A(H5N1) clade 2.3.4.4b viruses were isolated from domestic ducks in South Kalimantan, Indonesia, during April 2022. The viruses were genetically similar to those detected in East Asia during 2021-2022. Molecular surveillance of wild birds is needed to detect potential pandemic threats from avian influenza virus.PMID:38407163 | DOI:10.3201/eid3003.230973 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - February 26, 2024 Category: Infectious Diseases Authors: Hendra Wibawa Putut Eko Wibowo Arif Supriyadi Lestari Lestari Jessiaman Silaban Aziz Ahmad Fuadi Anna Januar Fiqri Retno Wulan Handayani Sri Handayani Irianingsih Zaza Fahmia Herdiyanto Mulyawan Syafrison Idris Nuryani Zainuddin Source Type: research
Recent Changes in Patterns of Mammal Infection with Highly Pathogenic Avian Influenza A(H5N1) Virus Worldwide
Emerg Infect Dis. 2024 Mar;30(3):444-452. doi: 10.3201/eid3003.231098.ABSTRACTWe reviewed information about mammals naturally infected by highly pathogenic avian influenza A virus subtype H5N1 during 2 periods: the current panzootic (2020-2023) and previous waves of infection (2003-2019). In the current panzootic, 26 countries have reported >48 mammal species infected by H5N1 virus; in some cases, the virus has affected thousands of individual animals. The geographic area and the number of species affected by the current event are considerably larger than in previous waves of infection. The most plausible source of mamm...
Source: Emerging Infectious Diseases - February 26, 2024 Category: Infectious Diseases Authors: Pablo I Plaza V íctor Gamarra-Toledo Juan Rodr íguez Euguí Sergio A Lambertucci Source Type: research
Highly Pathogenic Avian Influenza A(H5N1) Virus Clade 2.3.4.4b in Domestic Ducks, Indonesia, 2022
Emerg Infect Dis. 2024 Mar;30(3):586-590. doi: 10.3201/eid3003.230973.ABSTRACTHighly pathogenic avian influenza A(H5N1) clade 2.3.4.4b viruses were isolated from domestic ducks in South Kalimantan, Indonesia, during April 2022. The viruses were genetically similar to those detected in East Asia during 2021-2022. Molecular surveillance of wild birds is needed to detect potential pandemic threats from avian influenza virus.PMID:38407163 | DOI:10.3201/eid3003.230973 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - February 26, 2024 Category: Infectious Diseases Authors: Hendra Wibawa Putut Eko Wibowo Arif Supriyadi Lestari Lestari Jessiaman Silaban Aziz Ahmad Fuadi Anna Januar Fiqri Retno Wulan Handayani Sri Handayani Irianingsih Zaza Fahmia Herdiyanto Mulyawan Syafrison Idris Nuryani Zainuddin Source Type: research
Development of NP-Based Universal Vaccine for Influenza A Viruses
Vaccines (Basel). 2024 Feb 2;12(2):157. doi: 10.3390/vaccines12020157.ABSTRACTThe nucleoprotein (NP) is a vital target for the heterosubtypic immunity of CD8+ cytotoxic T lymphocytes (CTLs) due to its conservation among influenza virus subtypes. To further enhance the T cell immunity of NP, autophagy-inducing peptide C5 (AIP-C5) from the CFP10 protein of Mycobacterium tuberculosis was used. Mice were immunized intranasally (i.n.) with human adenoviral vectors, HAd-C5-NP(H7N9) or HAd-NP(H7N9), expressing NP of an H7N9 influenza virus with or without the AIP-C5, respectively. Both vaccines developed similar levels of NP-spec...
Source: Cancer Control - February 24, 2024 Category: Cancer & Oncology Authors: Ekramy E Sayedahmed Nelly O Elshafie Andrea P Dos Santos Chinnaswamy Jagannath Suryaprakash Sambhara Suresh K Mittal Source Type: research
Impact of the pandemic on various infectious diseases with different epidemiological patterns of seasonality, transmission and age
CONCLUSIONS: The impact of the pandemic is very different in these diseases. Pediatric and respiratory-transmitted seasonal viral infections are the ones that are most affected, but with different patterns of recovery to normality. Gastrointestinal bacterial infections suffer fewer variations, except for rotavirus. Gonorrhea do not interrupt its increasing trend seen in the pre-pandemic. Shingles show a slight post-pandemic increase. Several diseases with different epidemiological patterns have been studied for a sufficient period to observe how the acute phase of the pandemic emerges.PMID:38385502 (Source: Herpes)
Source: Herpes - February 22, 2024 Category: Infectious Diseases Authors: Juan Carlos Gasc ó-Laborda M Dolores Tirado-Balaguer Mar ía Gil-Fortuño Gabriela Dorina Deaconescu Oihana Sabalza-Bazt án Óscar Pérez-Olaso Iris G ómez-Alfaro Noelia Hern ández-Pérez Juan B Bellido-Blasco Source Type: research
The α-dystroglycan N-terminus is a broad-spectrum antiviral agent against SARS-CoV-2 and enveloped viruses
This study establishes soluble recombinant α-DGN as a broad-band, natural compound candidate therapeutic against enveloped viruses.PMID:38387750 | DOI:10.1016/j.antiviral.2024.105837 (Source: Antiviral Research)
Source: Antiviral Research - February 22, 2024 Category: Virology Authors: Maria Giulia Bigotti Katja Klein Esther S Gan Maria Anastasina Simon Andersson Olli Vapalahti Pekka Katajisto Maximilian Erdmann Andrew D Davidson Sarah J Butcher Ian Collinson Eng Eong Ooi Giuseppe Balistreri Andrea Brancaccio Yohei Yamauchi Source Type: research
The α-dystroglycan N-terminus is a broad-spectrum antiviral agent against SARS-CoV-2 and enveloped viruses
This study establishes soluble recombinant α-DGN as a broad-band, natural compound candidate therapeutic against enveloped viruses.PMID:38387750 | DOI:10.1016/j.antiviral.2024.105837 (Source: Cell Research)
Source: Cell Research - February 22, 2024 Category: Cytology Authors: Maria Giulia Bigotti Katja Klein Esther S Gan Maria Anastasina Simon Andersson Olli Vapalahti Pekka Katajisto Maximilian Erdmann Andrew D Davidson Sarah J Butcher Ian Collinson Eng Eong Ooi Giuseppe Balistreri Andrea Brancaccio Yohei Yamauchi Source Type: research
Impact of the pandemic on various infectious diseases with different epidemiological patterns of seasonality, transmission and age
CONCLUSIONS: The impact of the pandemic is very different in these diseases. Pediatric and respiratory-transmitted seasonal viral infections are the ones that are most affected, but with different patterns of recovery to normality. Gastrointestinal bacterial infections suffer fewer variations, except for rotavirus. Gonorrhea do not interrupt its increasing trend seen in the pre-pandemic. Shingles show a slight post-pandemic increase. Several diseases with different epidemiological patterns have been studied for a sufficient period to observe how the acute phase of the pandemic emerges.PMID:38385502 (Source: Herpes)
Source: Herpes - February 22, 2024 Category: Infectious Diseases Authors: Juan Carlos Gasc ó-Laborda M Dolores Tirado-Balaguer Mar ía Gil-Fortuño Gabriela Dorina Deaconescu Oihana Sabalza-Bazt án Óscar Pérez-Olaso Iris G ómez-Alfaro Noelia Hern ández-Pérez Juan B Bellido-Blasco Source Type: research
