Exploring viral aetiology in upper respiratory tract infections: insights from metagenomic next-generation sequencing in Swiss outpatients before and during the SARS-CoV-2 pandemic

CONCLUSIONS: Viral mNGS allowed the initial diagnosis to be retrospectively re-evaluated. Assuming reduced turnaround times, mNGS has the potential to directly guide the treatment of upper respiratory tract infections. On an epidemiological level, our study highlights the utility of mNGS in respiratory infection surveillance, allowing early detection of epidemics and providing information crucial for prevention.PMID:38587784 | DOI:10.57187/s.3797

Source: Swiss Medical Weekly - April 8, 2024 Category: General Medicine Authors: Verena Kufner Andrea C Frey Sara H Burkhard Stefan Schmutz Gabriela Ziltener Maryam Zaheri Caroline V Wiedmer Andreas Plate Alexandra Trkola Michael Huber Nicolas J Mueller Source Type: research