Safety of Popular Herbal Supplements in Lactating Women
The objectives of this review were to evaluate the safety of popular dietary supplements in breastfeeding mothers and the effects on the infants. Nine of the most popular herbal dietary supplements were identified based on the 2011 US market report of the top 10 selling botanicals and the most frequently received inquiries by the Ruth A. Lawrence Lactation Study Center at the University of Rochester Medical Center. Relevant publications were identified through June 2014 using PubMed and EMBASE; tertiary references, including the Drugs and Lactation Database and Natural Medicine Comprehensive Database, were also reviewed. T...
Source: Journal of Human Lactation - July 16, 2015 Category: Nursing Authors: Amer, M. R., Cipriano, G. C., Venci, J. V., Gandhi, M. A. Tags: Reviews Source Type: research

Paenibacillus oenotherae sp. nov. and Paenibacillus hemerocallicola sp. nov., Isolated from the Root of Herbaceous Plants.
Abstract Two Gram-staining-positive, aerobic, endospore-forming and motile bacteria designated DT7-4T and DLE-12T were isolated from the root of evening primrose (Oenothera biennis) and day lily (Hemerocallis fulva) respectively, and subjected to taxonomic characterization. The analysis of 16S rRNA gene sequences indicated that the two strains fell into two distinct phylogenetic clusters belonging to the genus Paenibacillus. Strain DT7-4T was mostly related to Paenibacillus phyllosphaerae PALXIL04T and Paenibacillus taihuensis THMBG22T with 96.3% 16S rRNA gene sequence similarity, and strain DLE-12T to Pae...
Source: International Journal of Systematic and Evolutionary Microbiology - May 14, 2015 Category: Microbiology Authors: Kim TS, Han JH, Joung Y, Kim SB Tags: Int J Syst Evol Microbiol Source Type: research

Use and perceived efficacy of complementary and alternative medicines after discontinuation of hormone therapy: a nested United Kingdom Collaborative Trial of Ovarian Cancer Screening cohort study
Conclusions: Although more women use over-the-counter medicines, behavioral/lifestyle approaches seem to provide better relief of VMS. There is a pressing need for better evidence-based lay information to support decision-making on CAM use for relief of VMS. (Source: Menopause)
Source: Menopause - March 28, 2015 Category: OBGYN Tags: Original Articles Source Type: research

Singlet oxygen autoxidation of vegetable oils: Evidences for lack of synergy between β-carotene and tocopherols
Publication date: 1 September 2015 Source:Food Chemistry, Volume 182 Author(s): Bogdan Smyk The synergy between β-carotene and tocopherols – antioxidants protecting oils from oxidation, was analyzed in a model system. The model used stripped borage and evening primrose oils. A chlorophyll extract, β-carotene and one of the tocopherols were added together or separately to the oils. Oil oxidation was initiated by singlet oxygen that was produced by chlorophylls irradiated with the use of a xenon lamp equipped with the cut-off 600nm filter. Experiments were carried out at two mole ratios of tocopherols to β-carotene...
Source: Food Chemistry - March 19, 2015 Category: Food Science Source Type: research

What's new in atopic eczema? An analysis of systematic reviews published in 2012 and 2013. Part 2. Treatment and prevention
Summary This review provides a summary of key findings from 22 systematic reviews on atopic eczema (AE) published over the 2‐year period from January 2012 to 31 December 2013, focusing on prevention and treatment of AE. For an update of systematic reviews on the epidemiology, mechanisms of disease and methodological issues, see Part 1 of this update. Based on current systematic review evidence, the most promising intervention for the prevention of AE is the use of probiotics (and possibly prebiotics) during the late stages of pregnancy and early life. Exposure to household pets, especially dogs, may also be protective, b...
Source: Clinical And Experimental Dermatology - January 27, 2015 Category: Dermatology Authors: V. Madhok, M. Futamura, K. S. Thomas, S. Barbarot Tags: Clinical dermatology ● Review article Source Type: research

The Effect of Evening Primrose Oil for the Prevention of Xerotic Cheilitis in Acne Patients Being Treated with Isotretinoin: A Pilot Study.
CONCLUSION: Our study suggests that the addition of EPO improved xerotic cheilitis in acne patients being treated with oral isotretinoin. However, besides TEWL and corneometry assessments, additional studies are required for a complete understanding of the role of EPO in xerotic cheilitis in acne patients being treated with oral isotretinoin. PMID: 25473222 [PubMed - as supplied by publisher] (Source: Annals of Dermatology)
Source: Annals of Dermatology - December 6, 2014 Category: Dermatology Tags: Ann Dermatol Source Type: research

Activity of liver enzymes in multiple sclerosis patients with Hot-nature diet and co-supplemented hemp seed, evening primrose oils intervention.
CONCLUSION: Selecting foods according to their Total antioxidant capacity such as co-supplemented hemp seed and evening primrose oils with Hot-nature diet affects antioxidant intake and can have beneficial effects on improving EDSS score and activity of liver enzymes in RRMS patients. PMID: 25453518 [PubMed - in process] (Source: Complementary Therapies in Medicine)
Source: Complementary Therapies in Medicine - December 1, 2014 Category: Complementary Medicine Authors: Rezapour-Firouzi S, Arefhosseini SR, Ebrahimi-Mamaghani M, Baradaran B, Sadeghihokmabad E, Torbati M, Mostafaei S, Chehreh M, Zamani F Tags: Complement Ther Med Source Type: research

The sterols isolated from evening primrose oil inhibit human colon adenocarcinoma cell proliferation and induce cell cycle arrest through upregulation of LXR
Publication date: January 2015 Source:Journal of Functional Foods, Volume 12 Author(s): S. Montserrat-de la Paz , M.A. Fernández-Arche , B. Bermúdez , M.D. García-Giménez Evening primrose oil (EPO) is widely used as a dietary supplement from which beneficial effects have been reported in rheumatic and arthritic conditions, atopic dermatitis, psoriasis, premenstrual and menopausal syndrome, and diabetic neuropathy. The aim of this study was to determine whether phytosterols isolated from evening primrose oil (PS-EPO), and its main components β-sitosterol and campesterol, affect proliferation, cell death, and th...
Source: Journal of Functional Foods - November 29, 2014 Category: Nutrition Source Type: research

Evening primrose oil ameliorates platelet aggregation and improves cardiac recovery in myocardial-infarct hypercholesterolemic rats.
This study was designed to examine its cholesterol lowering, antithrombotic and anti-inflammatory effects. High fat diet was administered for 4 weeks then MI was induced by isoproterenol (85 mg/kg/s.c./24 h). Treatment with EPO (5 or 10 gm/kg/day) for 6 weeks improved the electrocardiographic pattern, serum lipid profile, cardiac biomarkers as well as Platelet aggregation percent. We reported decreased serum level of TNF-α, IL-6 and COX-2 with attenuation of TNF-α and TGF-β in the cardiac homogenate. Moreover, histopathology revealed marked amelioration. Finally, we provide evidence that EPO improve cardiac recovery in ...
Source: International Journal of Physiology, Pathophysiology and Pharmacology - November 16, 2014 Category: Physiology Tags: Int J Physiol Pathophysiol Pharmacol Source Type: research

Local Topography Shapes Fine-Scale Spatial Genetic Structure in the Arkansas Valley Evening Primrose, Oenothera harringtonii (Onagraceae)
In this study, we explore fine-scale spatial genetic structure in Oenothera harringtonii (Onagraceae), an insect-pollinated, gravity-dispersed herb endemic to the grasslands of south-central and southeastern Colorado, USA. We genotyped 315 individuals with 11 microsatellite markers and utilized a combination of spatial autocorrelation analyses and landscape genetic models to relate life history traits and landscape features to dispersal processes. Spatial genetic structure was consistent with theoretical expectations of isolation by distance, but this pattern was weak (Sp = 0.00374). Anisotropic analyses indicated that spa...
Source: Journal of Heredity - October 17, 2014 Category: Research Authors: Rhodes, M. K., Fant, J. B., Skogen, K. A. Tags: Original Article Source Type: research

Evening primrose oil and celecoxib inhibited pathological angiogenesis, inflammation, and oxidative stress in adjuvant-induced arthritis: novel role of angiopoietin-1
Abstract Rheumatoid arthritis is a chronic inflammatory disease characterized by overproduction of inflammatory mediators along with undermined oxidative defensive mechanisms. Pathological angiogenesis was found to play a critical role in the progression of this disease. The current study was carried out to evaluate the anti-angiogenic, anti-inflammatory, and anti-oxidant effects of evening primrose oil (EPO), rich in gamma linolenic acid (GLA), either alone or in combination with aspirin or celecoxib, on adjuvant-induced arthritis. Arthritis was induced by subcutaneous injection of complete Freu...
Source: Inflammopharmacology - September 25, 2014 Category: Drugs & Pharmacology Source Type: research

Review of evidence for dietary influences on atopic dermatitis.
Abstract Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting children and adolescents worldwide. The relationship of AD to diet has been a matter of curiosity for many years. Here we look at the evidence in the literature of the association between AD and diet, and the effectiveness of elimination diets and diet supplementation in the management of AD. Several studies have found an association between clinical food allergy and AD, and more recent investigations have also suggested that dietary elements may promote late AD exacerbations. Diet elimination trials in select patients who are...
Source: Skin Therapy Letter - August 1, 2014 Category: Dermatology Authors: Mohajeri S, Newman SA Tags: Skin Therapy Lett Source Type: research

Arcadia Biosciences safflower oil product boosts omega-6 fatty acid
Davis-based Arcadia Biosciences Inc. is launching its product Sonova Ultra GLA Safflower Oil, which contains 55 percent of the omega-6 fatty acid that benefits skin health, weight management and women’s hormonal balance. Arcadia doesn’t sell it retail; rather it supplies the makers of supplements, energy bars and dietary aids. The primary traditional sources of omega-6 fatty acid are evening primrose or borage (starflower), both of which are difficult to cultivate. Arcadia genetically modified… (Source: bizjournals.com Health Care:Hospitals headlines)
Source: bizjournals.com Health Care:Hospitals headlines - June 17, 2014 Category: Hospital Management Authors: Mark Anderson Source Type: research

Gamma-Linolenic Acid Levels Correlate with Clinical Efficacy of Evening Primrose Oil in Patients with Atopic Dermatitis.
CONCLUSION: The clinical disease activity under EPO treatment correlates with the individual increase in plasma GLA levels. Thus, the results of this pilot study indicate that an increase in plasma GLA might be used as predictive parameter for responsiveness of AD to EPO therapy. PMID: 24435467 [PubMed - as supplied by publisher] (Source: Advances in Therapy)
Source: Advances in Therapy - January 17, 2014 Category: Drugs & Pharmacology Authors: Simon D, Eng PA, Borelli S, Kägi R, Zimmermann C, Zahner C, Drewe J, Hess L, Ferrari G, Lautenschlager S, Wüthrich B, Schmid-Grendelmeier P Tags: Adv Ther Source Type: research

Comparison of the antioxidant capacity of lipid‐soluble compounds in selected cold‐pressed oils using photochemiluminescence assay (PCL) and DPPH method
The paper describes the use of photochemiluminescence assay (PCL) and DPPH method for the measurement of lipid‐soluble antioxidants capacity (ACL) of six commercially available cold‐pressed, non‐refined flaxseed, walnut, rapeseed, pumpkin seed, evening primrose and black cumin oils. The cold‐pressed plant oils are rich in various valuable bioactive compounds e.g. tocopherols, tocotrienols, carotenoids, sterols, phospholipids and may reveal the antioxidant properties. The photochemiluminescence analysis (PCL) and free radical scavenging activity towards DPPH• were fully applicable for the evaluation of the antioxi...
Source: European Journal of Lipid Science and Technology - December 24, 2013 Category: Lipidology Authors: Maria Sielicka, Maria Małecka, Małgorzata Purłan Tags: Research Article Source Type: research