Molecules, Vol. 27, Pages 2391: Evening Primrose Oil Enhances Tamoxifen & rsquo;s Anticancer Activity against Breast Cancer Cells by Inducing Apoptosis, Inhibiting Angiogenesis, and Arresting the Cell Cycle
Conclusions: The most significant finding of this study was the confirmation of the anticancer activity of the natural product EPO, which potentiated the activity of the anticancer drug TAM against MCF-7 and MDA-MB-231 BC cell lines through the induction of apoptosis, inhibiting angiogenesis and halting cell proliferation. (Source: Molecules)
Source: Molecules - April 7, 2022 Category: Chemistry Authors: Mohammad M. Abd-Alhaseeb Sarah M. Massoud Fatma Elsayed Gamal A. Omran Ahmad Salahuddin Tags: Article Source Type: research

Differential gene expression associated with a floral scent polymorphism in the evening primrose Oenothera harringtonii (Onagraceae)
Plant volatiles play an important role in both plant-pollinator and plant-herbivore interactions. Intraspecific polymorphisms in volatile production are ubiquitous, but studies that explore underlying differen... (Source: BMC Genomics)
Source: BMC Genomics - February 12, 2022 Category: Genetics & Stem Cells Authors: Lindsey L. Bechen, Matthew G. Johnson, Geoffrey T. Broadhead, Rachel A. Levin, Rick P. Overson, Tania Jogesh, Jeremie B. Fant, Robert A. Raguso, Krissa A. Skogen and Norman J. Wickett Tags: Research Source Type: research

Molecules, Vol. 27, Pages 1221: Novel Evidence-Based Combination of Plant Extracts with Multitarget Mechanisms of Action for the Elimination of Hot Flashes during Menopause
a Andreadou Hot flashes are considered the most bothersome complaint during menopause. Although hormone therapy is an effective option to relieve hot flashes, it has been associated with significant side effects. The aim of our study is to suggest a novel combination of different plant extracts with distinct mechanisms of action against hot flashes. We selected the rhizome of Glycyrrhiza glabra L. (Fabaceae), the rhizome of Actaea racemosa L. (Ranunculaceae), the aerial parts of Hypericum perforatum L. (Hypericaceae) to produce extracts rich in bioactive phytochemicals and the seed oil of Oenothera biennis L. (Onagrace...
Source: Molecules - February 11, 2022 Category: Chemistry Authors: Maria Tsoumani Panagiota Efstathia Nikolaou Aikaterini Argyropoulou Ioulia Tseti Sofia Mitakou Ioanna Andreadou Tags: Article Source Type: research

Molecules, Vol. 26, Pages 7421: Herbal Products Used in Menopause and for Gynecological Disorders
OEMONOM Herbal products are often used as an alternative to pharmacological therapy. Menopausal symptoms and gynecological disorders (such as premenstrual syndrome and dysmenorrhea) are the indications where pharmacological therapy may have serious adverse events, hence many women prefer to use herbal products to help with these symptoms. Here, we reviewed plants and derived products, which are commonly used for the abovementioned indications, focusing on clinical data, safely profile and whether or not their use is justified. We noted that limited data are available on the use of some plants for alleviating the sympto...
Source: Molecules - December 8, 2021 Category: Chemistry Authors: Ma ša Kenda Nina Ko čevar Glavač Milan Nagy Marija Sollner Dolenc on behalf of the OEMONOM Tags: Review Source Type: research

Consensus Update for Systemic Treatment of Atopic Dermatitis
CONCLUSION: We look forward to implementing a new and updated consensus of systemic therapy in controlling patients with moderate-to-severe AD.PMID:34858001 | PMC:PMC8577915 | DOI:10.5021/ad.2021.33.6.497 (Source: Annals of Dermatology)
Source: Annals of Dermatology - December 3, 2021 Category: Dermatology Authors: Ji Hyun Lee Jung Eun Kim Gyeong-Hun Park Jung Min Bae Ji Yeon Byun Min Kyung Shin Tae Young Han Seung Phil Hong Yong Hyun Jang Hye One Kim Chan Ho Na Bark-Lynn Lew JiYoung Ahn Chang Ook Park Young-Joon Seo Yang Won Lee Sang Wook Son Eung Ho Choi Young Lip Source Type: research