In vitro assessment of selected Korean plants for antioxidant and antiacetylcholinesterase activities.
CONCLUSIONS: Considering complex multifactorial etiology of AD, the extracts of P. vulgaris var. lilacina (aerial part), O. biennis (seed) and P. nil (seed) may be safe and ideal candidates for future AD modifying therapies.
PMID: 29115888 [PubMed - in process] (Source: Pharmaceutical Biology)
Source: Pharmaceutical Biology - November 10, 2017 Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research
Pseudogracilibacillus endophyticus sp. nov., a moderately thermophilic and halophilic species isolated from plant root.
Abstract
A Gram-stain-positive strain, designated DT7-02(T), was isolated from the surface-sterilized root of Oenotherabiennis (evening primrose) and subjected to taxonomic characterization. Cells of DT7-02(T) were slender rod-shaped, motile by means of flagella, and oxidase- and catalase-positive. The colonies were circular, pinkish-yellow, opaque, glistering and 1-2 mm in diameter. The strain was moderately thermophilic and halophilic, as growth occurred at 20-44 °C (optimum 40 °C), pH 7-10 (optimum pH 8-9) and in the presence of 0-8 % of NaCl (optimum 4 %) in tryptic soy broth. The analysis ...
Source: International Journal of Systematic and Evolutionary Microbiology - November 10, 2017 Category: Microbiology Authors: Park J, Kim MK, Yun BR, Han JH, Kim SB Tags: Int J Syst Evol Microbiol Source Type: research
Effectiveness of Matricaria chamomilla (chamomile) extract on pain control of cyclic mastalgia: a double-blind randomised controlled trial.
This study was performed to determine the effectiveness of chamomile on pain control of cyclic mastalgia. This double-blind randomised controlled clinical trial was conducted on 60 patients with mastalgia referred to the breast clinic of an academic hospital, Mashhad University of Medical Sciences. The patients were randomly allocated into two groups: chamomile (n = 30) and placebo (n = 30). Primary outcomes were: (1) assessment of the visual analogue scale (VAS) and (2) assessment of the breast pain chart (BPC) 8 weeks after initial intervention. All the participants were asked to take drops three times a day ea...
Source: Journal of Obstetrics and Gynaecology - October 29, 2017 Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
Efficacy and Tolerability of Phytomedicines in Multiple Sclerosis Patients: A Review
AbstractMultiple sclerosis (MS) is a chronic inflammatory and demyelinating disorder of the central nervous system (CNS) that can cause cognition, mobility, and sensory impairments. It is considered one of the most common non-traumatic causes of disability in the world. The aim of the present article was to review the clinical evidence related to medicinal plants in the management of MS symptoms. Electronic databases, including the Cochrane Library, Pubmed, and Scopus, were searched for entries from 1966 to February 2017. Only clinical studies were included in this review. Different medicinal plants have positive effects o...
Source: CNS Drugs - September 25, 2017 Category: Neurology Source Type: research
Topical evening primrose oil as a possible therapeutic alternative in children with molluscum contagiosum
(Source: Clinical And Experimental Dermatology)
Source: Clinical And Experimental Dermatology - September 22, 2017 Category: Dermatology Authors: H. S. Kwon, J. H. Lee, G. M. Kim, E. H. Choi, J. M. Bae Tags: Correspondence Source Type: research
Drug-Herb Interactions in the Elderly Patient with IBD: a Growing Concern
Opinion statementInflammatory bowel disease (IBD), which includes conditions such as Crohn ’s disease and ulcerative colitis, is becoming more prevalent with the elderly being the fastest growing group. Parallel to this, there is an increasing interest in the use of complementary and alternative medicine (CAM). Nearly half of patients with IBD have used CAM at one time. The elderly pati ents, however, are burdened by comorbid conditions, polypharmacy, and altered functional status. With increasing use of complementary and alternative medicine in our elderly patients with IBD, it is vital for the provider to provide couns...
Source: Current Treatment Options in Gastroenterology - September 16, 2017 Category: Gastroenterology Source Type: research
Inhibition of nuclear factor-kappaB, cyclooxygenase-2, and metalloproteinase-9 expression by flavanols from evening primrose (Oenothera paradoxa) in human colon cancer SW-480 cells
Publication date: October 2017 Source:Journal of Functional Foods, Volume 37 Author(s): Katarzyna Owczarek, Elżbieta Hrabec, Jakub Fichna, Dorota Sosnowska, Maria Koziołkiewicz, Jacek Szymański, Urszula Lewandowska The present study examines the chemical composition of an evening primrose flavanol preparation (EPFP) and its chemopreventive activity in colon cancer SW-480 cells. EPFP was found to inhibit SW-480 cell viability by 67% vs. controls at 150µM catechin equivalents (CE) following 72h incubation (IC50 =65µM CE). EPFP decreased both NF-κB protein expression (33% vs. control at 100µM CE) and phosphory...
Source: Journal of Functional Foods - August 20, 2017 Category: Nutrition Source Type: research
The effects of vitamin D and evening primrose oil co-supplementation on lipid profiles and biomarkers of oxidative stress in vitamin D-deficient women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial
. (Source: Endocrine Research)
Source: Endocrine Research - July 25, 2017 Category: Endocrinology Authors: Khadijeh Nasri Sedighe Akrami Maryam Rahimi Mohsen Taghizadeh Masoud Behfar Mohammad Reza Mazandaranian Abbas Kheiry Mohammad Reza Memarzadeh Zatollah Asemi Source Type: research
Hydrocarbon degradation potential and plant growth-promoting activity of culturable endophytic bacteria of Lotus corniculatus and Oenothera biennis from a long-term polluted site.
Abstract
Many endophytic bacteria exert beneficial effects on their host, but still little is known about the bacteria associated with plants growing in areas heavily polluted by hydrocarbons. The aim of the study was characterization of culturable hydrocarbon-degrading endophytic bacteria associated with Lotus corniculatus L. and Oenothera biennis L. collected in long-term petroleum hydrocarbon-polluted site using culture-dependent and molecular approaches. A total of 26 hydrocarbon-degrading endophytes from these plants were isolated. Phylogenetic analyses classified the isolates into the phyla Proteobac...
Source: Environmental Science and Pollution Research International - July 6, 2017 Category: Environmental Health Authors: Pawlik M, Cania B, Thijs S, Vangronsveld J, Piotrowska-Seget Z Tags: Environ Sci Pollut Res Int Source Type: research
The Changes in Rats with Sciatic Nerve Crush Injury Supplemented with Evening Primrose Oil: Behavioural, Morphologic, and Morphometric Analysis.
In conclusion, EPO supplementation may be beneficial as a therapeutic option for disturbances of nerve interaction.
PMID: 28620418 [PubMed - in process] (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - June 19, 2017 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
What's the 'right' dose of a food supplement?
6 June 2017: Neal Patel, RPS spokesperson and pharmacist, appeared on Channel 4 ’s consumer programme Supershoppers to talk about the ‘right dose’ of vitamins and food supplements. Explaining why there is variation across retailers in the recommended doses of supplements like evening primrose oil, omega-3 fish oil and vitamin-B complex, Patel told viewers: “Supplements are regulated in the same way as foods, so they don’t have to have the same accurate dose as medicines. (Source: The Pharmaceutical Journal)
Source: The Pharmaceutical Journal - June 12, 2017 Category: Drugs & Pharmacology Source Type: research
Purification process for MUFA- and PUFA-based monoacylglycerols from edible oils.
Abstract
Important health benefits have been attributed to monoacylglycerols (MAGs) due to their various physiological functions, owing to which they become candidates for use as functional foods in order to prevent the onset of certain diseases such as colon cancer. In this work, six edible oils, namely: olive, linseed, sunflower, evening primrose, DHASCO(®) and ARASCO(®) have been processed to obtain different MUFA- and PUFA- based MAGs. First, the oils were hydrolyzed by means of an enzymatic process using porcine pancreatic lipase and then the reaction products were fractionated by using a liquid chr...
Source: Biochimie - June 5, 2017 Category: Biochemistry Authors: González-Fernández MJ, Ramos-Bueno RP, Rodríguez-García I, Guil-Guerrero JL Tags: Biochimie Source Type: research
Antiproliferative and antimicrobial efficacy of the compounds isolated from the roots of Oenothera biennis L.
ConclusionOenotheralanosterol B (3) exhibited stronger antiproliferative and antimicrobial potential with respect to the other compounds tested, whereas oenotheralanosterol A (1) was a potent inhibitor of ODC and CATD. Hence, it is suggested that these in‐vitro findings could be studied further in vivo for biological activity, safety evaluation and derivatization to enhance potency and efficacy. (Source: Journal of Pharmacy and Pharmacology)
Source: Journal of Pharmacy and Pharmacology - May 29, 2017 Category: Drugs & Pharmacology Authors: Shilpi Singh, Vijaya Dubey, Dhananjay Kumar Singh, Kaneez Fatima, Ateeque Ahmad, Suaib Luqman Tags: Research Paper Source Type: research
Therapeutic Effects of Korean Red Ginseng Extract in a Murine Model of Atopic Dermatitis: Anti-pruritic and Anti-inflammatory Mechanism.
Authors: Lee HJ, Cho SH
Abstract
Korean red ginseng (KRG) and ginsenosides exhibit diverse biological effects, including anti-inflammatory and anti-allergic. We aimed to investigate the therapeutic effect of KRG in a murine model of atopic dermatitis (AD) is mediated whether by diminishing the pruritus or by suppressing the inflammation. Thirty NC/Nga mice were randomly divided to 5 groups. AD-like skin lesions were induced by percutaneous challenge with 2,4,6-trinitro-1-chrolobenzene (TNCB) on the ears and backs of NC/Nga mice. KRG extract, evening primrose oil, cyclosporine, and phosphate-buffered saline...
Source: Journal of Korean Medical Science - March 2, 2017 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
