Colonic spider naevi in a middle-aged man
Introduction A 59-year-old man was seen in outpatient clinic with a 1-year history of abdominal cramping and non-bloody diarrhoea. His only medical history comprised hypercholesterolaemia and oesophagogastric reflux, for which he took simvastatin and lansoprazole. He did not show cutaneous spider naevi and there was no history of liver disease or use of oestrogen or hormone replacement medications. CT of the abdomen and pelvis showed a long segment of moderate sigmoid colonic wall thickening (figure 1A) with perifocal fat stranding and free fluid in keeping with acute sigmoiditis. Feeding vessels were patent with no eviden...
Source: Gut - February 23, 2024 Category: Gastroenterology Authors: Hunter, H., Johnston, A. J., Said, W., Wong, N. A. Tags: GUT Snapshot, Gut Editor ' s quiz: GI snapshot Source Type: research
Tirzepatide: A Review in Type 2 Diabetes
In conclusion, tirzepatide i s a valuable addition to the treatment options for T2DM. (Source: Drugs)
Source: Drugs - February 23, 2024 Category: Drugs & Pharmacology Source Type: research
Salmonella Typhi sternoclavicular abscess with osteomyelitis —a rare case report
We present a case of Salmonella osteomyelitis and discuss the importance of microbiological diagnosis of osteomyelitis in diagnosing unusual pathogens from unusual sites. This case report is unique due to its site and difference in clinical presentation. The difference in presentation in an elderly immunocompetent male with no major comorbidities was different from other reported cases. Our patient was successfully managed with surgical debridement followed by a series of vacuum dressings and intravenous antibiotics for 6 weeks. (Source: Indian Journal of Thoracic and Cardiovascular Surgery)
Source: Indian Journal of Thoracic and Cardiovascular Surgery - February 20, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research
Effective coverage of curative child health services in Ethiopia: analysis of the Demographic and Health Survey and Service Provision Assessment survey
Conclusions
System-wide interventions are required to address both demand-side and supply-side bottlenecks in the provision of child health services if child health-related targets are to be achieved in Ethiopia. (Source: BMJ Open)
Source: BMJ Open - February 20, 2024 Category: General Medicine Authors: Haile, T. G., Benova, L., Mirkuzie, A. H., Asefa, A. Tags: Open access, Health services research Source Type: research
A survey into the utilization of probiotics and medicinal plants among individuals afflicted with gastrointestinal disorders in healthcare institutions in Sa ïda, Algeria
Conclusion: The understanding of probiotics is still in its infancy, whereas phytotherapy is more widely accepted by patients. Nonetheless, patients are open to the exploration of natural alternatives to conventional medicines.PMID:38369815 | DOI:10.1080/19932820.2024.2317492 (Source: Libyan Journal of Medicine)
Source: Libyan Journal of Medicine - February 19, 2024 Category: General Medicine Authors: Lamia Abir Tazi Yasmina Benabdesslem Sabrina Amara Kadda Hachem Source Type: research
A survey into the utilization of probiotics and medicinal plants among individuals afflicted with gastrointestinal disorders in healthcare institutions in Sa ïda, Algeria
Conclusion: The understanding of probiotics is still in its infancy, whereas phytotherapy is more widely accepted by patients. Nonetheless, patients are open to the exploration of natural alternatives to conventional medicines.PMID:38369815 | PMC:PMC10878339 | DOI:10.1080/19932820.2024.2317492 (Source: Libyan Journal of Medicine)
Source: Libyan Journal of Medicine - February 19, 2024 Category: General Medicine Authors: Lamia Abir Tazi Yasmina Benabdesslem Sabrina Amara Kadda Hachem Source Type: research
Comparative evaluation of the detection rate, workflow and associated costs of a multiplex PCR panel versus conventional methods in diagnosis of infectious gastroenteritis
Conclusion. Multiplex PCR panels are valuable tools for laboratory identification of infectious agents causing diarrhoea. The higher costs of such a multiplex PCR panel might be outweighed by the higher detection rate, ease of handling, rapid results and most likely improved patient management. However, these panels do not provide information on antimicrobial susceptibility testing. Therefore, if this is necessary for targeted therapy or if outbreak monitoring and control is required, specimens must still be cultured.PMID:38362908 | DOI:10.1099/jmm.0.001795 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - February 16, 2024 Category: Microbiology Authors: J Ambrosius-Eichner M Hogardt A Berger G Dultz R Idris V A J Kempf T A Wichelhaus Source Type: research
Comparative evaluation of the detection rate, workflow and associated costs of a multiplex PCR panel versus conventional methods in diagnosis of infectious gastroenteritis
Conclusion. Multiplex PCR panels are valuable tools for laboratory identification of infectious agents causing diarrhoea. The higher costs of such a multiplex PCR panel might be outweighed by the higher detection rate, ease of handling, rapid results and most likely improved patient management. However, these panels do not provide information on antimicrobial susceptibility testing. Therefore, if this is necessary for targeted therapy or if outbreak monitoring and control is required, specimens must still be cultured.PMID:38362908 | DOI:10.1099/jmm.0.001795 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - February 16, 2024 Category: Microbiology Authors: J Ambrosius-Eichner M Hogardt A Berger G Dultz R Idris V A J Kempf T A Wichelhaus Source Type: research
Comparative evaluation of the detection rate, workflow and associated costs of a multiplex PCR panel versus conventional methods in diagnosis of infectious gastroenteritis
Conclusion. Multiplex PCR panels are valuable tools for laboratory identification of infectious agents causing diarrhoea. The higher costs of such a multiplex PCR panel might be outweighed by the higher detection rate, ease of handling, rapid results and most likely improved patient management. However, these panels do not provide information on antimicrobial susceptibility testing. Therefore, if this is necessary for targeted therapy or if outbreak monitoring and control is required, specimens must still be cultured.PMID:38362908 | DOI:10.1099/jmm.0.001795 (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - February 16, 2024 Category: Microbiology Authors: J Ambrosius-Eichner M Hogardt A Berger G Dultz R Idris V A J Kempf T A Wichelhaus Source Type: research
Estimating excess mortality and economic burden of Clostridioides difficile infections and recurrences during 2015 –2019: The RECUR England study
Clostridioides difficile is a common source of healthcare-associated infection, with symptoms ranging from mild diarrhoea to life-threatening colon damage [1,2]. While most C. difficile infection (CDI) cases are acquired in healthcare facilities, the incidence of community-associated CDIs has been increasing [1,3]. Nearly a quarter of patients experience a recurrent CDI (rCDI) episode. The recurrence rate increases with each subsequent episode, and 40% –65% of patients with one recurrence experience ≥2 recurrences [4]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - February 15, 2024 Category: Infectious Diseases Authors: Subrata Ghosh, Ana Antunes, Hanna Rinta-Kokko, Elena Chaparova, Sarah Lay-Flurrie, Aurore Tricotel, Fredrik L Andersson Source Type: research
Diarrhoea of unknown cause: medical treatment in a stepwise mannerManagement of Idiopathic Diarrhoea Based on Experience of Step-Up Medical Treatment
Scand J Gastroenterol. 2024 Feb 11:1-4. doi: 10.1080/00365521.2024.2313061. Online ahead of print.ABSTRACTThe basic principle for the treatment of idiopathic diarrhoea (functional diarrhoea K59.1) is to delay transit through the gut in order to promote the absorption of electrolytes and water. Under mild conditions, bulking agents may suffice. With increasing severity, antidiarrhoeal pharmaceuticals may be added in a stepwise manner. In diarrhoea of unknown aetiology, peripherally-acting opioid receptor agonists, such as loperamide, are first-line treatment and forms the pharmaceutical basis of antidiarrheal treatment. As ...
Source: Scandinavian Journal of Gastroenterology - February 12, 2024 Category: Gastroenterology Authors: Ann-Sofie Jansson-Rehnberg Asbj ørn Mohr Drewes Jon Sponheim Christer Borgfelt Andreas M ünch Wilhelm Graf Magnus Simr én Greger Lindberg Per M Hellstr öm Source Type: research
Microscopic colitis: what's in a name? An overview from clinical and histological perspectives
Microscopic colitis presents as chronic watery diarrhoea and leads to a significant disease burden. Specific histological characteristics are key to diagnosing microscopic colitis and to specify its subtypes collagenous colitis or lymphocytic colitis. Histological hallmarks of microscopic colitis are an increased inflammatory infiltrate in the lamina propria without significant crypt architectural distortion and intraepithelial lymphocytosis, which is generally more prominent in lymphocytic colitis. (Source: Diagnostic Histopathology)
Source: Diagnostic Histopathology - February 10, 2024 Category: Pathology Authors: Chella S van der Post, Danny Goudkade, Bas PM Verhaegh Tags: Mini-symposium: gastrointestinal and hepato-pancreato-biliary pathology Source Type: research
Disaster after disaster: the outbreak of infectious diseases in Pakistan in the wake of 2022 floods
Ann Med Surg (Lond). 2023 Dec 8;86(2):891-898. doi: 10.1097/MS9.0000000000001597. eCollection 2024 Feb.ABSTRACTIn June 2022, Pakistan witnessed catastrophic floods, affecting millions of people. The ensuing epidemics of cholera, cryptosporidiosis, rotavirus infections, generalized diarrhoea, typhoid and paratyphoid fevers, as well as the frequency of vector-borne diseases including malaria and dengue fever, are studied in this investigation. It also explores the latest outbreak of poliomyelitis and the frequency of respiratory diseases such COVID-19, diphtheria, and tuberculosis, as well as how floods have contributed to s...
Source: Annals of Medicine - February 9, 2024 Category: Internal Medicine Authors: Marcel Alied Abdus Salam Sayed Mansoor Sediqi Patrick Amanning Kwaah Linh Tran Nguyen Tien Huy Source Type: research
