Pharmacological Chemolysis of Uric Acid Lithiasis in A Patient with Crohn's Disease
We present the case of a male patient with Crohn's disease and carrying an ileostomy. He was diagnosed with uric acid urolithiasis (stone size of 11 mm located in the left pyeloureteral junction) after presenting to the emergency room during an episode of left renal colic. Results of the 24-hour urinalysis showed an acidic pH (pH <5), consistent with hyperuricosuria. The suspicion of uric acid lithiasis was confirmed after performing an X-ray diffraction analysis of a lithiasic fragment that passed during acute renal colic. The patient was prescribed with urinary alkalinisers (medical treatment) and dietary recommendati...
Source: Archivos Espanoles de Urologia - January 8, 2024 Category: Urology & Nephrology Authors: Rosa Mar ía Gras Martínez Marta Diranzo Garc ía Ariana Álvarez Barrera Miguel Beltr án Puig Fernando Mart ínez Martínez Emilio L ópez Alcina Source Type: research
Prevalence of intestinal parasites in HIV/AIDS-infected patients with correlation to CD4+ T-cell count at hospital in Eastern India
CONCLUSIONS: This study has shed light that low CD4+ T-cell count appears to be a factor for intestinal parasitic infections and development of diarrhoea. Regular screening and treatment of intestinal parasitic infections is very important in overall improvement in quality of life of HIV/AIDS patients. Nevertheless, sanitary hygiene practices and deworming are needed to enhance the control of infection in the affected areas.PMID:38186830 | PMC:PMC10771173 | DOI:10.4103/jfmpc.jfmpc_806_23 (Source: Primary Care)
Source: Primary Care - January 8, 2024 Category: Primary Care Authors: Kumari Seema Abhay Kumar Manju Boipai Manoj Kumar Ashok Kumar Sharma Source Type: research
Pharmacological Chemolysis of Uric Acid Lithiasis in A Patient with Crohn's Disease
We present the case of a male patient with Crohn's disease and carrying an ileostomy. He was diagnosed with uric acid urolithiasis (stone size of 11 mm located in the left pyeloureteral junction) after presenting to the emergency room during an episode of left renal colic. Results of the 24-hour urinalysis showed an acidic pH (pH <5), consistent with hyperuricosuria. The suspicion of uric acid lithiasis was confirmed after performing an X-ray diffraction analysis of a lithiasic fragment that passed during acute renal colic. The patient was prescribed with urinary alkalinisers (medical treatment) and dietary recommendati...
Source: Archivos Espanoles de Urologia - January 8, 2024 Category: Urology & Nephrology Authors: Rosa Mar ía Gras Martínez Marta Diranzo Garc ía Ariana Álvarez Barrera Miguel Beltr án Puig Fernando Mart ínez Martínez Emilio L ópez Alcina Source Type: research
Effect of rapid colonic transit on stool microbiome and short-chain fatty acids in diarrhoea-predominant irritable bowel syndrome
In a recent article in GUT,1 we showed that, among 194 patients with diarrhoea-predominant irritable bowel syndrome (IBS-D), 43 had altered bile acid (BA) metabolism (ABAM) (serum 7αC4>52 ng/mL). Patients with ABAM, had faster colonic transit (CT), lower α diversity and a different microbial compositional profile based on β diversity compared with IBS-D without ABAM. There were no significant differences in the stool short-chain fatty acid (SCFA) concentrations between the two groups.1 There is evidence that transit impacts gut microbiome composition and diversity.2 We wish to extend the previous analys...
Source: Gut - January 5, 2024 Category: Gastroenterology Authors: BouSaba, J., Zheng, T., Dilmaghani, S., Johnson, S., Chen, J., Camilleri, M. Tags: Gut PostScript Source Type: research
Clostridioides difficile infections, recurrences, and clinical outcomes in real-world settings from 2015 –2019: The RECUR England study
Clostridioides difficile infection (CDI) is one of the most common causes of healthcare-associated diarrhoea and is being increasingly acquired in the community [1,2]. Clinical manifestations range from mild diarrhoea to life-threatening complications, including colitis, toxic megacolon, colon perforation, and sepsis [1]. Risk factors for CDI include antibiotic use, old age ( ≥65 years), hospitalisations, and immunocompromised conditions [1]. Use of proton-pump inhibitors (PPIs), H2-receptor blockers, and gastrointestinal procedures (e.g. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - January 5, 2024 Category: Infectious Diseases Authors: Subrata Ghosh, Ana Antunes, Hanna Rinta-Kokko, Elena Chaparova, Sarah Lay-Flurrie, Aurore Tricotel, Fredrik L Andersson Source Type: research
Comparative Genomics of Clostridioides difficile
Adv Exp Med Biol. 2024;1435:199-218. doi: 10.1007/978-3-031-42108-2_10.ABSTRACTClostridioides difficile, a Gram-positive spore-forming anaerobic bacterium, has rapidly emerged as the leading cause of nosocomial diarrhoea in hospitals. The availability of large numbers of genome sequences, mainly due to the use of next-generation sequencing methods, has undoubtedly shown their immense advantages in the determination of C. difficile population structure. The implementation of fine-scale comparative genomic approaches has paved the way for global transmission and recurrence studies, as well as more targeted studies, such as t...
Source: Advances in Experimental Medicine and Biology - January 4, 2024 Category: Research Authors: Sandra Janezic Julian R Garneau Marc Monot Source Type: research
Ribotypes and New Virulent Strains Across Europe
Adv Exp Med Biol. 2024;1435:151-168. doi: 10.1007/978-3-031-42108-2_8.ABSTRACTClostridioides (formerly Clostridium) difficile is a major bacterial cause of post-antibiotic diarrhoea. The epidemiology of C. difficile infections (CDIs) has dramatically changed since the early 2000s, with an increasing incidence and severity across Europe. This trend is partly due to the emergence and rapid worldwide spread of the hypervirulent and epidemic PCR ribotype 027. Profiles of patients with CDI have also evolved, with description of community-acquired (CA) infections in patients with no traditional risk factors for CDI. However, epi...
Source: Advances in Experimental Medicine and Biology - January 4, 2024 Category: Research Authors: Jeanne Couturier Kerrie Davies Fr édéric Barbut Source Type: research
Comparative Genomics of Clostridioides difficile
Adv Exp Med Biol. 2024;1435:199-218. doi: 10.1007/978-3-031-42108-2_10.ABSTRACTClostridioides difficile, a Gram-positive spore-forming anaerobic bacterium, has rapidly emerged as the leading cause of nosocomial diarrhoea in hospitals. The availability of large numbers of genome sequences, mainly due to the use of next-generation sequencing methods, has undoubtedly shown their immense advantages in the determination of C. difficile population structure. The implementation of fine-scale comparative genomic approaches has paved the way for global transmission and recurrence studies, as well as more targeted studies, such as t...
Source: Advances in Experimental Medicine and Biology - January 4, 2024 Category: Research Authors: Sandra Janezic Julian R Garneau Marc Monot Source Type: research
Ribotypes and New Virulent Strains Across Europe
Adv Exp Med Biol. 2024;1435:151-168. doi: 10.1007/978-3-031-42108-2_8.ABSTRACTClostridioides (formerly Clostridium) difficile is a major bacterial cause of post-antibiotic diarrhoea. The epidemiology of C. difficile infections (CDIs) has dramatically changed since the early 2000s, with an increasing incidence and severity across Europe. This trend is partly due to the emergence and rapid worldwide spread of the hypervirulent and epidemic PCR ribotype 027. Profiles of patients with CDI have also evolved, with description of community-acquired (CA) infections in patients with no traditional risk factors for CDI. However, epi...
Source: Advances in Experimental Medicine and Biology - January 4, 2024 Category: Research Authors: Jeanne Couturier Kerrie Davies Fr édéric Barbut Source Type: research
Comparative Genomics of Clostridioides difficile
Adv Exp Med Biol. 2024;1435:199-218. doi: 10.1007/978-3-031-42108-2_10.ABSTRACTClostridioides difficile, a Gram-positive spore-forming anaerobic bacterium, has rapidly emerged as the leading cause of nosocomial diarrhoea in hospitals. The availability of large numbers of genome sequences, mainly due to the use of next-generation sequencing methods, has undoubtedly shown their immense advantages in the determination of C. difficile population structure. The implementation of fine-scale comparative genomic approaches has paved the way for global transmission and recurrence studies, as well as more targeted studies, such as t...
Source: Advances in Experimental Medicine and Biology - January 4, 2024 Category: Research Authors: Sandra Janezic Julian R Garneau Marc Monot Source Type: research
Ribotypes and New Virulent Strains Across Europe
Adv Exp Med Biol. 2024;1435:151-168. doi: 10.1007/978-3-031-42108-2_8.ABSTRACTClostridioides (formerly Clostridium) difficile is a major bacterial cause of post-antibiotic diarrhoea. The epidemiology of C. difficile infections (CDIs) has dramatically changed since the early 2000s, with an increasing incidence and severity across Europe. This trend is partly due to the emergence and rapid worldwide spread of the hypervirulent and epidemic PCR ribotype 027. Profiles of patients with CDI have also evolved, with description of community-acquired (CA) infections in patients with no traditional risk factors for CDI. However, epi...
Source: Advances in Experimental Medicine and Biology - January 4, 2024 Category: Research Authors: Jeanne Couturier Kerrie Davies Fr édéric Barbut Source Type: research
