Clostridioides difficile infections, recurrences, and clinical outcomes in real-world settings from 2015 –2019: The RECUR England study

Clostridioides difficile infection (CDI) is one of the most common causes of healthcare-associated diarrhoea and is being increasingly acquired in the community [1,2]. Clinical manifestations range from mild diarrhoea to life-threatening complications, including colitis, toxic megacolon, colon perforation, and sepsis [1]. Risk factors for CDI include antibiotic use, old age ( ≥65 years), hospitalisations, and immunocompromised conditions [1]. Use of proton-pump inhibitors (PPIs), H2-receptor blockers, and gastrointestinal procedures (e.g.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research