Ginsenoside Rh4 Facilitates the Sensitivity of Renal Cell Carcinoma to Ferroptosis via the NRF2 Pathway
CONCLUSIONS: Rh4 made RCC cells more sensitive to ferroptosis by inhibiting the NRF2 signaling and suppressing the expression of antioxidant enzymes. Therefore, combining Rh4 with ferroptosis-inducing reagents to treat RCC had potential therapeutic application.PMID:38583003 | DOI:10.56434/j.arch.esp.urol.20247702.16 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Huandong Zhao Ruimin Ding Jiarui Han Source Type: research
Is Unilateral Lymphadenectomy an Option in Selected Patients with Prostate Cancer?
CONCLUSIONS: In our experience, the majority of patients with unilateral PCa had exclusively ipsilateral LNI. However, sparing contralateral LN dissection in unilateral PCa should not be an option. To date, extended pelvic LN dissection remains the gold standard for N-staging and cannot be replaced yet by unilateral pelvic LN dissection until high quality evidence supports this scenario.PMID:38583004 | DOI:10.56434/j.arch.esp.urol.20247702.17 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Baraa Nakdali Kassab Pedro De Pablos-Rodr íguez Álvaro Gómez Ferrer Antonio Coy Garc ía Ana Calatrava Fons Fuensanta Arag ón Juan Casanova Ram ón-Borja Miguel Ram írez-Backhaus Source Type: research
Effect of miR-590-3p/DKK1 Axis on the Progression of Wilms' Tumour
CONCLUSIONS: Through the regulation of DKK1, miR-590-3p accelerated the invasion and proliferation of Wilms' tumour. The study suggests that the miR-590-3p/DKK1 axis represents a novel mechanism in Wilms' tumour.PMID:38583005 | DOI:10.56434/j.arch.esp.urol.20247702.18 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Hong Wang Yiliang Zhang Source Type: research
Enhancing Sperm Motility Parameters in Patients with Asthenospermia: A Combined Approach of Acupuncture at Fusiguan Point and Tamoxifen Citrate Tablets
CONCLUSIONS: The combination of acupuncture at Fusiguan point and tamoxifen citrate tablets exerts a notably positive effect on sperm motility in individuals diagnosed with asthenospermia.PMID:38583006 | DOI:10.56434/j.arch.esp.urol.20247702.19 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Junyu Luo Yaohui Luo Chunlai Dong Guangli Qi Liang Zhong Fang Liu Weibo Wen Source Type: research
Analysis of the Clinicopathological Characteristics and Prognosis of Patients with Nonurothelial Bladder Cancer
CONCLUSIONS: NUBC is a rare pathological subtype of bladder cancer with a poor prognosis, and SqCC and AC are the most common histological subtypes of NUBC. Early diagnosis, radical cystectomy, and a focus on patients with lymph node metastasis, advanced pT stage, or SqCC may be helpful for ensuring the survival of NUBC patients.PMID:38583007 | DOI:10.56434/j.arch.esp.urol.20247702.20 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Haotian Ren Keruo Wang Chunyu Liu Source Type: research
The Impact of Delirium after Radical Prostatectomy on Cognitive Function and Health Perception during the Recovery Period
CONCLUSIONS: Patients experiencing delirium after radical prostatectomy are at a higher risk of cognitive function impairment and disease threat perception. A significant correlation exists between postoperative delirium and cognitive function as well as health perception.PMID:38583008 | DOI:10.56434/j.arch.esp.urol.20247702.21 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Shuang Qiao Xiaoqian Liu Ying Wang Shuang Chen Wenwen Tong Yueyu Zhang Source Type: research
The Prognostic Value of the Combination of the Prognostic Nutritional Index and the Lymphocyte:Monocyte Ratio for the Prediction of Patients with Muscle-Invasive Bladder Cancer
CONCLUSIONS: Low preoperative PNI and LMR values are indicative of poor prognosis in patients with MIBC. The efficacy of their combination was better than that of the factors independently.PMID:38583009 | DOI:10.56434/j.arch.esp.urol.20247702.22 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Xiaoping Zhang Quan Liu Kai Yi Shigui Liu Jie Lan Source Type: research
Long Non-Coding RNA NUTM2A-AS1/miR-376a-3p/PRMT5 Axis Promotes Prostate Cancer Progression
CONCLUSIONS: NUTM2A-AS1 promotes cancer stem cell-like traits in PCa cells by targeting PRMT5 through miR-376a-3p. Therefore, these NUTM2A-AS1-based novel insights into tumour therapy hold promise for patients with PCa.PMID:38583010 | DOI:10.56434/j.arch.esp.urol.20247702.23 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Hongfen Han Zheng Li Lei Bi Jing Zhang Source Type: research
Effect of miR-1297 on Kidney Injury in Rats with Diabetic Nephropathy through the PTEN/PI3K/AKT Pathway
CONCLUSIONS: AntagomiR-1297 can mitigate renal fibrosis, renal inflammation, apoptosis, and oxidative stress levels through the PTEN/PI3K/AKT pathway.PMID:38583011 | DOI:10.56434/j.arch.esp.urol.20247702.24 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Na Chen Hailing Liu Xiaobo Jiang Nina Tang Wenxing Fan Wenxuan Ji Zhu Zhou Source Type: research
Dishevelled Segment Polarity Protein 3 (DVL3) Induced by Bacterial LPS Promotes the Proliferation and Migration of Prostate Cancer Cells through the TLR4 Pathway
CONCLUSIONS: Bacterial LPS-induced DVL3 promoted the multiplication and migration of prostate cancer cells through the TLR4 pathway. This study offers a valuable reference for the development and clinical application of targeted drugs for prostate cancer.PMID:38583012 | DOI:10.56434/j.arch.esp.urol.20247702.25 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Yakun Zhang Na Lin Xianyan Liu Tingting Yao Source Type: research
Development of a Nomogram Model to Predict the Risk of Stricture Recurrence after Urethroplasty: A Retrospective Study
CONCLUSIONS: From the data of this study, it can be deduced that the influencing factors of stricture recurrence after urethroplasty include the length of stricture segment, history of urethroplasty and smoking history of 3 months before surgery. Using the above factors as a basis to construct a predictive nomogram model is helpful to screen high-risk patients with recurrence of stricture after urethroplasty.PMID:38583013 | DOI:10.56434/j.arch.esp.urol.20247702.26 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Hang Guo Zhenghao Dai Lichang Zhong Yiwen Jiang Yuting Lu Tao Liang Source Type: research
Influencing Factors of Delirium during Recovery in Urological Postoperative Patients Undergoing Sevoflurane Anaesthesia
CONCLUSIONS: Age, history of diabetes, operation time, ASA classification and sevoflurane inhalation concentration are the influencing factors.PMID:38583014 | DOI:10.56434/j.arch.esp.urol.20247702.27 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Chuan He Yuhong Sun Yu Meng Huanli Qian Source Type: research
Predictive Value of Magnetic Resonance Imaging Radiomics Combined with Serum PSA for the Extracapsular Extension of Prostate Cancer Prediction
CONCLUSIONS: The combination of MRI radiomics and PSA can accurately predict the extracapsular extension of prostate cancer; Thus, it is a favorable reference for subsequent precise diagnosis and treatment.PMID:38583015 | DOI:10.56434/j.arch.esp.urol.20247702.28 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Jialing Wu Xiang Yu Zhiwei Zuo Jianhao Li Feizhou Du Peng Wang Rui Jiang Source Type: research
Giant Midline Prostatic Cyst: An Unusual Cause of Acute Urinary Retention
We presented a striking case of a giant midline cyst and detailed its diagnosis, evolution, and treatment. From this case, we offered a comparison of congenital intraprostatic midline cysts, namely, Müller's cysts and utricle cysts. A 40-year-old male experienced recurrent urinary retention. A 10 × 11 mm2 cyst in the mid-prostatic region was diagnosed through transrectal ultrasound, leading to a transperineal puncture as a minimally invasive intervention. Seven years later, the cyst recurred, manifesting obstructive symptoms such as a weak urinary stream, frequent urination, and residual urine sensation. Laparoscopic sur...
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Mar ía Teresa Melgarejo Segura Miguel Arrabal Mart ín Source Type: research
Ginsenoside Rh4 Facilitates the Sensitivity of Renal Cell Carcinoma to Ferroptosis via the NRF2 Pathway
CONCLUSIONS: Rh4 made RCC cells more sensitive to ferroptosis by inhibiting the NRF2 signaling and suppressing the expression of antioxidant enzymes. Therefore, combining Rh4 with ferroptosis-inducing reagents to treat RCC had potential therapeutic application.PMID:38583003 | DOI:10.56434/j.arch.esp.urol.20247702.16 (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 7, 2024 Category: Urology & Nephrology Authors: Huandong Zhao Ruimin Ding Jiarui Han Source Type: research
