[Comparative analysis of the treatment of mid-shaft and distal hypospadias according to Snodgrass surgical repair and Mathieu technique.]
CONCLUSIONS: The exhaustive selection of patients seems the key in the succesful correction of these types of hypospadias. Despite both techniques are comparable in terms of the type of patient in which they could be applied and both techniques present similar rates in terms of fistulas and stenosis/retractions of the neomeatus (most frequent complications in this type of repairs), we consider that the characteristics of the patient should be prioritized before the preference of the surgeon to reach higher success rates. PMID: 31223122 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - June 23, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Prognostic factors of mortality in patients with urothelial bladder tumor treated with radical cistectomy.]
CONCLUSIONS: Age, anesthetic risk, presence of hydronephrosis, pT and pN stage were identified as independent predictors of GM, as well as pT and pN stage for CSM. PMID: 31223123 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - June 23, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Diagnostic and therapeutic management in a series of 1156 patients with the diagnosis of prostate cancer in Castilla y Leon during 2014.]
CONCLUSIONS: Differed strategies still accounted for a small percentage of treatments. PR and RT/BT were of choice in patients with localized stages of the disease and younger than 70 years. More advanced stages and older patients were treated with HT mainly. Age is postulated as the main factor involved in therapeutic decision making. PMID: 31223124 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - June 23, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Circulating prostate cells and bone marrow micrometastasis are determinant in risk and time to biochemical progression in localized prostate cancer.]
Authors: Murray NP, Aedo S, Fuentealba C, Reyes E, Minzer S, Salazar A Abstract INTRODUCTION: Minimal residual disease (MRD) is that which remains after curative therapy for prostate cancer. It has the potential for growth and later cause metastasis. After radical prostatectomy, the detection of circulating prostate cells (CPCs) and bone marrow micro-metastasis could represent different types of MRD. We proposed to determine the biochemical failure free survival rates, the time to biochemical failure after 10 years of follow-up and the presence of CPCs and micro-metastasis in patients treated with RP for pathologic...
Source: Archivos Espanoles de Urologia - June 23, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Spanish consensus document for the diagnosis, treatment and management of neurogenic bladder.]
CONCLUSIONS: This article presents a version of guidelines for patients with NB. The guidelines define the clinical profile of patients to provide the best evidence- based care and also an overview of the current drug and surgical treatments of NB. PMID: 31223126 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - June 23, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Radium 223 for the treatment of metastatic castration-resistant prostate cancer.
Authors: Miranda J, Viñal D, Pinto Á Abstract The treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) has evolved dramatically in the recent years with the approval of several new drugs. Together with other treatment modalities including chemotherapy, hormonal therapy and immunotherapy, radiopharmaceuticals have recently been incorporated to the therapeutic scenario of prostate cancer with the approval of Radium 223 dichloride (Ra-223) for the treatment of mCRPC patients with symptomatic bone metastasis and no visceral metastases. Radiopharmaceuticals have long been used...
Source: Archivos Espanoles de Urologia - June 23, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Laparoscopic donor nephrectomy versus open donor nephrectomy: Outcomes from a single transplant center.
CONCLUSIONS: Data from our series demonstrate that outcomes and renal function follow up over time were similar among both groups. In expert hands, this altruistic procedure can be performed with a minimally invasive approach without an increased complication rate or compromising renal function in donors. PMID: 31223128 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - June 23, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Application of ureteral access sheath under direct visualization: Description of a technique for difficult ureters.
Authors: Ebiloglu T, Kaya E, Zor M, Kopru B, Tomruk H, Sarikaya S, Bedir S Abstract OBJECTIVES: To introduce a new technique for the placement of ureteral access sheaths (UAS) when there is failure in standard UAS placement. MATERIALS AND METHODS: Between March 2014 and June 2016, a total of 25 patients had difficulty while UAS placement during F-URS procedures. The placement of UAS in these patients was accomplished by utilizing the technique outlined in this study. The causes of difficulty in UAS placement, kinds of UAS deformation, ureteric injuries, and operation time were recorded for all procedures condu...
Source: Archivos Espanoles de Urologia - June 23, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Do success rate, complications of transobturator tape procedure differ based on experienced surgeon or residents?
CONCLUSIONS: There was statistically significant increased groin pain in the early period in TOT procedures performed by the residents. However, the complications observed in both groups did not affect the success rate or patient satisfaction. PMID: 31223130 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - June 23, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Acute urine retention due to herlyn-Werner-Wunderlinch syndrome.]
CONCLUSIONS: In this case, as in others, nonspecific and variable symptoms may delay the diagnosis, which may lead to late complications such as endometriosis, adhesion syndrome, collections and infertility. Treatment suppresses pain, improves reproductive capacity and prevents late complications. PMID: 31223131 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - June 23, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Renal cell carcinoma with (tubule) papillary architecture. Report of three cases and bibliographic review.]
CONCLUSION: The RCCtpcc is usually a low grade and stage subtype of epithelial RCC. It predominates in the sixth decade of life, although cases have already been described in children and young adults. It has a typical immunohistochemical pattern with positive CK7, vimentine, VT and smooth muscle antigen, and negative CD10. They usually have a low malignant potential. PMID: 31223132 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - June 23, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Treatment of uretero-renal stones with shock wave lithotripsy. Results and complications with the dornier gemini emse 220f-XXP.]
CONCLUSIONS: Treatment with extracorporeal lithotripsy in small lithiasis and in well-selected patients obtains good results with a low rate of complications regardless of sex and body mass index. PMID: 31070130 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Axitinib in real life, analysis of our results.]
CONCLUSIONS: Axitinib is a drug that has been shown to increase PFS after 1st line progression, with a tolerable toxic profile. With the approval of nivolumab and cabozantinib, the place of Axitinib in sequential therapy is yet to be defined. PMID: 31070131 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Evaluation of our series of first biopsies and rebiopsies by applying a prostate cancer risk calculator.]
CONCLUSIONS: The application of a prostate cancer risk calculator in candidates for first biopsy allows optimization of the test, although it loses effectiveness in patients with previous negative PB. PMID: 31070132 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Multiparametric magnetic resonance imaging in prostate cancer detection.
CONCLUSIONS: The identification of highly suspicious lesions in prostate mpMRI examination has moderate sensitivity and high specificity in the detection of prostate cancer in patients with multiple previous negative biopsies. The use of mpMRI should be considered as a screening tool for prostate cancer in routine clinical practice. PMID: 31070133 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Long-term functional outcome and complications of male suburethral slings in the management of post-prostatectomy incontinence: A prospective five-year follow-up study.
CONCLUSIONS: Male slings are safe and effective. Although we observed an increase in "de novo" urgency, in our experience, slings seemed to maintain their efficacy during long-term follow-up, and the risks of urethral erosion are low. PMID: 31070134 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Incidence of genitourinary pathology in the emergency department.]
CONCLUSIONS: Age over 60 years, hospital admission as final resolution and infection/sepsis diagnosis were independent features for further waiting time in the Emergency Department. Persistent pain and symptoms of infection/sepsis behaved as independent features for hospital admission. PMID: 31070135 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Vaginal repair of vesico-vaginal fistula: Experience at a tertiary care center in Venezuela.]
CONCLUSION: The vaginal technique for the treatment of VVF is safe and effective with low recurrence rate and complications. PMID: 31070136 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Does preoperative hydronephrosis affect the stone-free rate of micro-percutaneous nephrolithotomy?
In this study, 66 consecutive patients were included and divided into 2 groups:patients without preoperative hydronephrosis (group-1) and patients with preoperative hydronephrosis (group-2).Both groups were compared for age, gender, body mass index (BMI), stone burden, stone location, fluoroscopy and operative time, blood loss, stone-free rate and perioperative and postoperative complication rates. Parameters were analyzed using univariate and multivariate analyses for the stone-free rate. RESULTS: The mean age, gender, BMI, stone location, and blood loss were similar in both groups (p>0.05). Stone burden in group-2...
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Dermal graft surgery for Peyronie's disease: Long term results at a 15 years follow-up.
CONCLUSIONS: Dermal graft substitution surgery for Peyronie's disease allows to obtain good functional results with durable satisfaction of the patients on long term follow up. PMID: 31070138 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Laparoscopic renal cyst excision: Large simple renal cyst treatment with renal cell carcinoma cells in its wall. Histogenetic considerations and bibliographic review.]
CONCLUSION: The development of a renal cell carcinoma in simple renal cysts is a very infrequent pathology.Laparoscopic total cystectomy is a minimally invasive therapeutic option for the treatment of renal cell carcinoma originating in a simple renal cyst, although it is of an important size. We establish the hypothesis of migration of the cells of the renal collecting tubes into the cyst wall to explain the malignant transformation of the renal simple cyst. PMID: 31070139 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Post-hysterectomy uretero-vaginal fistula: Laparoscopic management with ureteroneocystostomy and psoas hitch.]
CONCLUSION: Laparoscopic ureteroneocystostomy with a psoas hitch for ureterovaginal fistula secondary to hysterectomy is a safe and feasible option for patients with gynecologic distal ureteral injury, with excellent results and low morbidity. PMID: 31070140 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

A unique case of aggressive uterine cancer in a 45-year-old man with persistent M ├╝llerian duct syndrome.
CONCLUSIONS: Persistent mullerian duct syndrome can be associated with aggressive non-testicular malignancies, especially uterine cancer, in normally virilized males. PMID: 31070141 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Cutaneous penile necrosis after Nesbit corporoplasty.]
Authors: Elizalde Benito FX, Urra Palos M, Ramírez Fabián M, Blasco Beltrán B, Elizalde Benito ÁG, Quintana Martínez I Abstract PMID: 31070142 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Acute pyelonephritis and renal abscess due to ureteral stone.
Authors: Otaola Arca H, Rodríguez Sánchez L, Rodríguez Sánchez L, Páez Borda Á Abstract PMID: 31070143 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 11, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Current status of robotic surgery in urology.
Authors: Ogaya-Piniés G Abstract A few decades ago, minimal invasive  surgery changed the way we understand and perform surgery. Before the revolution of minimal invasive techniques, we accepted and justified a certain degree of trauma on the tissues in order to provide benefit and healing  to the patient. With the adoption of new technologies, we realized that we could achieve  the same or even better results with fewer side  effects. PMID: 30945648 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

How to build a robotic program.
CONCLUSIONS: Individual economic factors of local healthcare settings must be evaluated when planning for a new robotics program. The high cost of the robotic surgical platform is best offset with a large surgical volumen,interdisciplinary utilization of the technology may be the solution. A mature, experienced surgeon is integral to the success of a new robotics program. Define procedures to be performed, necessary training, staff involved,equipment, facilities, setting-up, economical resources and marketing are important issues to be teaken into account before acquiring a surgical robotic system. PMID: 30945649 [PubM...
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Robotic-assisted radical prostatectomy: The teaching.
CONCLUSIONS: Virtual models in Robotic surgery has changed the perspective teaching process of medicine. Theoretical knowledge, virtual training and Proctor's advice are essential steps in the learning curve. Future directions,evolution of virtual models in a similar fashion to the real scenario. PMID: 30945650 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Technical features and the demonstrated advantages of the Retzius sparing robotic prostatectomy.
CONCLUSION: Long-term, prospective, comparative,  and possibly randomized studies are needed but RSP is  now spreading all over the world thanks to the different advantages that offers to patients. The most recognized benefit is surely the achievement of early continence, as well documented in multiple studies and papers, without compromising the oncological outcomes. PMID: 30945651 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Robot-assisted extended pelvic lymph node dissection in prostate cancer. When and how?
CONCLUSION: Extended pelvic lymph node dissection is recommended to be performed at the time of RARP in intermediate and high-risk patients and cannot be replaced by other modalities. A benefit in terms of oncologic outcomes remains to be established. The robot assisted approach offers shorter length of hospital stay, lower transfusion rates and comparable outcomes compared to other surgical approaches. PMID: 30945652 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Complications of robot assisted radical prostatectomy.
Authors: Moncada I, López I, Ascencios J, Krishnappa P, Subirá D Abstract The urology community has adopted robot-assisted radical prostatectomy (RARP) as the most preferred surgical therapeutic approach in the management of localized prostate cancer. Safety and potential complications of RARP should be clearly known prior to attempting the surgery. The complications have been categorized as anesthesia & patient positioning related, vascular, non-vascular and delayed. European Associationof Urology guidelines recommend the use of Clavien-Dindo grading to report surgical complications.The medi...
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Salvage robot-assisted radical prostatectomy following failed local treatments.
Authors: Linares Espinós E, Ogaya-Piniés G, Martínez-Salamanca JI Abstract Prostate cancer represents the most commonly diagnosed cancer in men and is the second-leading cause of cancer related death in the United States. Primary treatment for prostate cancer includes radiotherapy or ablative procedures such as cryotherapy, and high-intensity focused ultrasound (HIFU). Unfortunately, a large proportion of these patients, especially with high risk features, may experience disease recurrence within 10 years. Management of recurrent localized prostate cancer is heterogeneous, and radical surgery r...
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

What's new in robotic partial nephrectomy.
CONCLUSION: RAPN can be considered to be the gold standard approach to minimally invasive nephronsparing surgery with equivalent oncological and  renal functional outcomes and superior perioperative outcomes when compared to OPN. Newer techniques and developments in robotic technology have contributed to improved outcomes following RAPN. PMID: 30945655 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Robotic radical cystectomy.
CONCLUSIONS: RARC is a technically feasible and safe approach, with oncological, pathological and perioperative results, at least, equivalent to ORC. PMID: 30945656 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Robotic intracorporeal ileal conduit: Technical aspects.
CONCLUSIONS: The advantages of the robotic platform concerning postoperative outcomes may be more evident if the procedure is done in an intracorporeal fashion. Proper knowledge and mastery of the technical aspects of this procedure are critical. PMID: 30945657 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Intracorporeal neobladder.
CONCLUSIONS: The results from the intraorporeal neobladders series appear to be promising, but high-quality randomized controlled trials comparing to ICUD to ECUD should be performed in order to define the advantages and  disadvantages of totally intracorporeal urinary diversion and its future role in the treatment of invasive bladder cancer. PMID: 30945658 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Intracorporeal orthotopic neobladder formation: Why not to do it?
CONCLUSIONS: Herein we review the studies that propose advantages of the intracorporeal diversion, as well as the studies that do not demonstrate any advantage to this approach. Some of the proposedadvantages addressed include decreased stricture rate, lower complications and shorter hospitalization. Furthermore, we address the issues of the steep learningcurve and the impact on resident education. We conclude that the proposed benefits of an intracorporeal approach to urinary diversion are not substantiated and it is the preference of the authors to primarily perform extracorporeal urinary diversions. PMID: 30945659 [...
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Role of robotic surgery in functional urology.
Authors: Moscatiello P, Sánchez Gallego MD, Carracedo Calvo D Abstract Three-dimensional, high-definition images, small instruments with endowrist technology, ergonomic position and the easiness to teach, are possibly the main reasons why robotic surgery will continue to gain ground to others forms of surgery. The current applications of robotics in functional urology are: the correction of pelvic organ prolapse, the correction of female stress urinary incontinence (artificial urinary sphincter) and the treatment of chronic pelvic pain (pudendal nerveneurolysis). In this paper, we explain our robotic techniq...
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Current status of robotic kidney transplant and its future.
CONCLUSION: Despite its limitations, RAKT seems to be an attractive, feasible, safe, and reproducible surgery. It offers surgical advantages and a lower complication rate, especially in obese patients, and delivers functional outcomes comparable to those achieved using OKT. PMID: 30945661 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

3D imaging and urology: Why 3D reconstruction will be mandatory before performing surgery.
CONCLUSION: 3D surgical planning should be mandatory in pediatric urology to perform the safest, the most accurate and effective surgery as possible. PMID: 30945662 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 5, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

New paradigms in prostate cancer.
Authors: Álvarez-Maestro M, Gómez Rivas J Abstract Prostate cancer remains the most common malignancy diagnosed in men andis the third leading cause of cancer death among men in the United States and Europe.On this basis, it is anticipated by many that the rates of prostate cancer mortality may rise in the years to come. As a result, a number of new challenges have emerged in prostate cancer, forcing urologists to consider new paradigms in the disease management: both to improve methods of detection and to be more effective in managing the likely increasing numbers of men with advanced disease. PM...
Source: Archivos Espanoles de Urologia - March 12, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

DIAGNOSIS. Screening: Actual trends on PSA marker. When, who, how?
Authors: Baccaglini W, Cathelineau X, Araújo Glina FP, Medina LG, Sotelo R, Carneiro A, Sanchez-Salas R Abstract Prostate cancer (PCa) is the most common non-skin malignancy among men world-wide. PCa incidence is higher among African American (AA) menin comparison to the white population. Men with a previous history of PCa in first-line relatives carry also an increased risk for this disease. The incidence of PCa diminished in United States (US) since the publication in 2012 of US Preventive Service Task Force (USPSTF), in which PCa screening was bestowed with a grade D of recommendation. Nonetheless, locall...
Source: Archivos Espanoles de Urologia - March 12, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Biomarkers in prostate cancer management. Is there something new?
CONCLUSIONS: The use of genetic PCa biomarkers has a unique role in screening, diagnosis, surveillance, risk stratification and treatment for this disease. It is important that providers be able to recommend the appropriatetest for each individual patient and circumstance within the disease. In the present time, no biomarker can be recommended over another, and large-scale and multi-institutional studies are required to validate the efficacy and cost utility of these new technologies. PMID: 30855011 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - March 12, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

New markers in prostate cancer: Genomics.
Authors: Fuessel S, Wirth MP Abstract Prostate cancer (PCa) is a very heterogeneous disease with unknown outcome at the time of first diagnosis. Multiple clinicopathological parameters andmodern imaging approaches are currently used to detect PCa and to assess the necessity of early or delayed treatment according to the predicted aggressivenessof the tumor. Despite regular adjustments of predictive systems based on histopathological factors such as the Gleason grading system or based on prostate MRI such as the Prostate Imaging Reporting and Data System (PIRADS)these tools for risk stratification of PCa patients st...
Source: Archivos Espanoles de Urologia - March 12, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

New markers in prostate cancer: Inmunohistochemical.
Authors: Compérat E Abstract Although pathology is the gold standard for confirming the diagnosis of prostate cancer (PCa), several marker for diagnosis may be useful and will helpin doubtful cases to confirm the diagnosis of PCa. Therfore it is important to spread the knowledge of immunomarker, in order to improve the clinicians understanding of stains and their usefulness.Like in other organs, clinicians and pathologists would like not to rely only on pathological criteria such as PSA, Gleason score, tumor size and pT stage, but also on tumor stains, permitting to predict prognosis and patients outcome, es...
Source: Archivos Espanoles de Urologia - March 12, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Magnetic resonance imaging and prostate cancer: Perspectives from the UK, Europe and USA.
In this report we will discuss the use of mpMRI in the United Kingdom, Europe and in the United States of America, comparing the most important guidelines and majorpapers over the last few years. PMID: 30855014 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - March 12, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

New standards in prostate biopsy.
CONCLUSION: The introduction of multiparametric prostate MRI has the potential to change the way that we diagnose men with prostate cancer. PMID: 30855015 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - March 12, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

The future of molecular and functional imaging in prostate cancer.
Authors: Renard-Penna R, Gauthé M Abstract The major goal of prostate cancer imaging in the next decade will be more accurate disease diagnostic, characterization and staging through the synthesisof anatomic, functional and molecular imaging.Changes are happening regarding the use of prostate MRI for evaluating primary prostate cancer and PET CT for the staging and recurrence staging of prostate cancer.This review presents a multidisciplinary perspective of the role of prostate MRI and molecular imaging in prostate cancer. PMID: 30855016 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - March 12, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

TREATMENT. Active surveillance in intermediate risk prostate cancer.
CONCLUSION: Active surveillance for men at the favorable end of intermediate risk prostate cancer is an appealing alternative to radical therapy, but carries amodest but increased risk of metastatic disease compared to low risk cancer. Many biomarkers are currently being evaluated to enhance precise risk stratification of this important subgroup of patients. PMID: 30855017 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - March 12, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Future of focal therapy for the treatment of prostate cancer- european section of urotechnology (ESUT) position.
CONCLUSION: Focal therapy is a new option in the armamentarium of PCa. Technological improvements and the development of novel energy sources should make it possible to treat lesions with even greater precision, while limiting the risk of side effects. In the future, we should probably be able to effectively expand the indications of this technique to include more aggressive tumours. PMID: 30855018 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - March 12, 2019 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research