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[Arteriovenous fistula (AVF) of the kidney in a patient with Cowden's syndrome].
Authors: Jiménez Parra JD, García DG, Varas LT, Calvo JJ PMID: 27243078 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - June 1, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Renal injury grade IV: laceration and secondary urinoma. Conservative management].
Authors: Saez-Barranquero F, Herrera-Imbroda B, Sanchez-Soler N, Carmona-Sanchez EI, Castillo-Gallardo E, Machuc Santa-Cruz FJ PMID: 27243079 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - June 1, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Oncological results in high grade prostate cancer treated surgically.
Authors: Aguilera A, Alonso-Dorrego JM, Bañuelos B, Cisneros J, González P, Díez J Abstract OBJECTIVES: Prostate cancer is considered a tumour with a long natural history. However, its highrisk variants exhibit variable behaviour. We analyse the factors that affect BR and CSS (multivariate, Kaplan Meier). METHODS: From 1997 to 2013, 657 patients were operated of a high-grade prostate cancer (pT2b 7.2%, pT3a 73%, pT3b 18.3%, pT4 1.5%). Gleason score was ≥8 in 23% of cases. Percentage of PSMs was 46.1%. Mean follow-up was 113 months (24-192). RESULTS: BR occurred in 36.5%. Patients with Gleason score
Source: Archivos Espanoles de Urologia - May 27, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Usefulness of urodynamics in the treatment of mixed urinary incontinence in women with suburethral slings.
CONCLUSION: We demonstrated worst results in MUI in patients with urinary incontinence undergoing SS. The urodynamic study gives a better prognosis reliability in the treatment of female urinary incontinence with SS. PMID: 27225054 [PubMed - as supplied by publisher] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 27, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Practical refinaments in simplified laparoscopic pyeloplasty].
CONCLUSIONS: The LP is a feasible and safe technique for the surgical correction of UPJO, and maneuvers presented in this study simplify the procedure and may be applied in other laparoscopic procedures. PMID: 27225055 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 27, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

The effect of asymptomatic histological prostatitis on sexual function and lower urinary tract symptoms.
Authors: Urkmez A, Yuksel OH, Uruc F, Akan S, Yildirim C, Sahin A, Verit A Abstract OBJECTIVE: Prostatitis affects 10-14% of men of all ages and ethnicities. More than 50% of the men experience episodes of prostatitis at one time of their lives. Patients with CP typically have longlasting genitourinary/pelvic pain and obstructive and/or irritative voiding symptoms. Sexual dysfunction and psychological symptoms are frequently added to these symptoms. We also investigated the relationship between sexual functions, and lower urinary system symptoms, and asymptomatic histological prostatitis detected on transrectal ult...
Source: Archivos Espanoles de Urologia - May 27, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Hematologic neoplasms with testicular involvement.
CONCLUSIONS: Currently the mortality rate in cases of relapse of hematologic malignancy in the testicle has declined despite the sharp rise in its incidence. This is because of, as in our case, early diagnosis and the combined use of chemotherapy, radiotherapy and surgery. This has been achieved through an interdisciplinary collaboration of urologists, hematologists, oncologists and radiotherapists. PMID: 27225057 [PubMed - as supplied by publisher] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 27, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Clear cell renal cell carcinoma metastasized by a breast ductal carcinoma.
CONCLUSIONS: Awareness of this phenomenon should always be kept in mind by urologist in patients with a known history of a previous malignancy and by pathologists when finding a renal tumor with an unusual or dimorphic morphology. Immunohistochemistry plays an important role to establish the exact diagnosis. PMID: 27225058 [PubMed - as supplied by publisher] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - May 27, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Evolution of urinary lithiasis composition in a Spanish health care area over the last four decades.
Authors: Martín-Way DA, Puche-Sanz I, Pascual-Geler M, Vázquez-Alonso F, Flores-Martín JF, Cózar-Olmo JM Abstract OBJECTIVE: To provide an updated epidemiological description of urinary lithiasis in a health area in the Western hemisphere over the past four decades. METHODS: 2704 urinary lithiases analysed in our institution between 1980 and 2015 were retrospectively reviewed. They were analyzed using polarized light microscopy, and in the case this method had questionable results we used X-ray diffraction. The variables collected were the lithiasis chemical composition (oxalates, ph...
Source: Archivos Espanoles de Urologia - May 27, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

The fasting calcium/creatinine ratio in patients with calcium stones and the relation with hypercalciuria and phosphocalcium metabolism.
CONCLUSION: Increased fasting calcium/creatinine determines increased 24 hours calcium excretion, although the sensitivity and specificity to determine hypercalciuria is not high. PMID: 27068369 [PubMed - as supplied by publisher] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 14, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Cold ischemia and renal graft survival: A paired analysis comparing first and second grafts from the same donor.
Authors: Puche-Sanz I, Flores-Martín JF, Vázquez-Alonso F, Expósito-Ruiz M, Bravo-Soto J, Vicente-Prados J, Cózar-Olmo JM Abstract OBJECTIVE: To compare the characteristics, clinical course, and survival of pairs of renal grafts from the same donor, with special interest in cold ischemia times (CIT) as a risk factor for graft survival. METHODS: We retrospectively reviewed paired grafts originating from the same cadaver donor from our prospectively recorded database of kidney transplants, from 1987 to 2015. We selected and divided them into two groups depending on whether they corresp...
Source: Archivos Espanoles de Urologia - April 14, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Ventral corpora cavernosa corporoplasty for the treatment of severe penile incurvation in Pediatric Urology].
Authors: Mieles Cerchar MJ, Gosalbez Rafel R, Miguélez Lago C Abstract Hypospadias is a congenital pathology of the male genitalia that we diagnose and treat more every day. Due to an increase of case load we must have at hand a large quantity of surgical techniques for its correct treatment. Ventral corporoplasty of the corpora cavernosa is one of them that will help us to successfully treat the most severe cases within this variety which is the pathology itself. We performed a prospective study in Malaga, Spain between 2010-2015. We review the technic and its indications, and the authors personal series wi...
Source: Archivos Espanoles de Urologia - April 14, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Renal hemorrhage after ESWL: From small hematoma to renal blowout.
CONCLUSIONS: Even though hemorrhage is an infrequent complication after ESWL, it should be suspected when the patient presents compatible clinical symptoms, since even though most cases are resolved in a conservative manner, on some occasions specific treatments for the hemorrhage are necessary. Old age and the presence of vascular comorbidities seem to be related to a higher risk of hemorrhage after ESWL. PMID: 27068372 [PubMed - as supplied by publisher] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 14, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Prostatic biopsy: From organ biopsy to lesion biopsy. The role of MRI and MRI based biopsy systems].
CONCLUSIONS: Multiparametric MRI is already an essential test in diagnostic algorithms for prostate cancer and the systems that enable to biopsy the lesion identified are day by day a more integrated tool in the urological daily practice, and urological procedures that will enable a more precise diagnosis leading to a personalized treatment for each patient. PMID: 27068373 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - April 14, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Other radiological lesions of the Lower Urinary Tract in patients after isolated pelvic radiotherapy and combined with surgery.
Authors: Méndez Rubio S, Salinas Casado J, Vírseda Chamorro M, Gutiérrez Martín P, Esteban Fuertes M, Moreno Sierra J Abstract INTRODUCTION: The cystographic study of patients who have undergone radiotherapy (RT) and pelvic surgeries is uncommon in the literature, not described in patients without complications, and mostly related to urinary fistulae. OBJECTIVE: The study of the lower urinary tract (LUT) by cystography in these patients, with a description of some other types of radiation lesions. METHODS: 127 cystographies have been performed (88 men and 39 women) in consecutive...
Source: Archivos Espanoles de Urologia - March 11, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Comparative study for the efficacy and safety of percutaneous nefhrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS) for the treatment of 2-3,5 cm kidney stones.
CONCLUSION: RIRS was found to be a safe and efficient procedure with a short hospital stay. Overall, RIRS can be considered as an alternative to PCNL for the treatment of renal stones smaller than 3.5 cm. PMID: 26959965 [PubMed - as supplied by publisher] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - March 11, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Folic acid: Primary prevention of neural tube defects. Literature Review].
Authors: Llamas Centeno MJ, Miguélez Lago C Abstract Neural tube defects (NTD) are the most common congenital malformations of the nervous system, they have a multifactorial etiology, are caused by exposure to chemical, physical or biological toxic agents, factors deficiency, diabetes, obesity, hyperthermia, genetic alterations and unknown causes. Some of these factors are associated with malnutrition by interfering with the folic acid metabolic pathway, the vitamin responsible for neural tube closure. Its deficit produce anomalies that can cause abortions, stillbirths or newborn serious injuries that cause ...
Source: Archivos Espanoles de Urologia - March 11, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Scrotal tumors.
CONCLUSIONS: Scrotal lesions in the elderly should be excised and submitted for pathological examination. The basal cell carcinoma of the scrotum appears as a plaque, nodule or ulcer. Long-term surveillance is recommended for these patients. Leiomyoma of the scrotum is presented as a non-ulcerative nodule and his treatment is complete surgical excision. PMID: 26959967 [PubMed - as supplied by publisher] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - March 11, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Dermatological side effects of intravesical Mitomycin C: Delayed hypersensitivity.
CONCLUSIONS: Contact dermatitis of non-allergic origin is a common side effect described in many instances in the literature, on the other hand exists dermatitis secondary to delayed hypersensitivity type IV much less common, requiring treatment with corticosteroids. PMID: 26959968 [PubMed - as supplied by publisher] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - March 11, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Use of urinary concentrations in mg/dl in relation to absolute values in 24-hour samples for the evaluation of lithogenic factors in stone forming patients.
Authors: Arrabal-Polo MA, Cano-García MC, Hidalgo-Agullo G, Roletto-Salmo L Abstract OBJECTIVE: The aim of this study is to analyze urine concentrations (mg/dl) of different lithogenic factors in a sample of 24 h as a predictor of these changes rather than absolute values depend on the volume of diuresis. METHODS: A total of 131 patients from the North Almeria Health Management Area (Spain) with urinary calstone disease in whom a metabolic study was indicated were included from June 2014 to May 2015. The concentrations of calcium, oxalate, uric acid, citrate and magnesium were measured in the urine, and ...
Source: Archivos Espanoles de Urologia - March 11, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Prostatic specific antigen. From its early days until becoming a prostate cancer biomarker.
Authors: Dellavedova T Abstract Prostate-specific antigen (PSA) has been since the mid 80's the most commonly used biomarker for measuring current and future risk of prostate cancer, for its early detection and to measure response to treatments and detecting recurrence in all stages of the disease. PSA's early development came along with progress in the field of immunology, which allowed detection and study of antigens from different tissues and fluids when injecting them into rabbits to promote immune response. Rubin Flocks in 1960 was the first to investigate and discover prostate-specific antigens in benign and ...
Source: Archivos Espanoles de Urologia - February 11, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Anastomic urethroplasty in bulbar urethral stricture. 13 years experience in a department of urology.
Authors: Sáez-Barranquero F, Herrera-Imbroda B, Yáñez-Gálvez A, Sánchez-Soler N, Castillo-Gallardo E, Cantero-Mellado JA, Julve-Villalta E, Machuca-Santa Cruz FJ Abstract Urethral stenosis is a common disease in the clinical practice of urology, with a major impact on the quality of life of patients. The anastomotic urethroplasty is a technique with very precise indications usually membranous or bulbar urethra stenosis with a length of 3 cm or up to 7 cm when it is secondary to urethral disruptions (no stenosis) after pelvic trauma. OBJECTIVE: We review anastomotic urethroplas...
Source: Archivos Espanoles de Urologia - February 11, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Influence of barbed suture in laparoscopic radical prostatectomy.
CONCLUSIONS: The use of bidirectional barbed suture (Quill®) for vesicourethral anastomosis in laparoscopic radical prostatectomy, when compared with the conventional suture, shortens surgical time, reduces urinary fistula rate, catheter duration and hospital stay, as the anastomosis is easily performed and prevents leakage. PMID: 26856736 [PubMed - as supplied by publisher] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - February 11, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Diagnosis challenge of atypical spindle cells neoplasm of the spermatic cord.
CONCLUSIONS: Soft tissues neoplasms of the spermatic cord may occur in an unusual way and they may be a real challenge to diagnose. PMID: 26856737 [PubMed - as supplied by publisher] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - February 11, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Treatment with hydrochlorothiazide and alendronate in patients with stones and bone mineral density loss. Evolution of bone metabolism and calciuria with medical treatment.
Authors: Arrabal-Martín M, González-Torres S, Cano-García MC, Poyatos-Andújar A, Abad-Menor F, Arrabal-Polo MA Abstract OBJECTIVES: Treatment of calcium stones is based on diet and pharmacological measures such as the use of thiazides and other drugs. The aim of this study is to assess the effect of alendronate on hydrochlorothiazide on urinary calcium and bone mineral density in patients with calcium stones. METHODS: Prospective observational study involving 77 patients with relapsing calcium stones divided into 2 groups according to treatment received. Group 1: 36 patients treated ...
Source: Archivos Espanoles de Urologia - February 11, 2016 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Chairman of Clinical Departments planification, organizational and management portfolio].
Authors: Repullo JR, Oteo LA Abstract Portfolio methodology is widely applied to training, particularly in medical education and for medical trainees. Some Spanish Institutions (National University of Distance Learning and National School of Public Health) are using a seven dimension Portfolio in the field of Clinical Management, which could be used as conceptual framework and checklist for building up different documents for planning, programming and evaluating the new experiences of Clinical Units based on clinical management initiatives. This paper describe the Portfolio in short, takes into consideration its po...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Evaluation of the maturity of a Urology Department in terms of Quality. Management and Quality improvement operative objectives].
CONCLUSIONS: The management of a clinical department cannot be limited to continuous improvisation. A process management approach is necessary, finishing with the usual defects of the generated product (variability, errors, omissions, waiting lists). Excellence in the quality of health care is an essential objective in every healthcare organization and standardization models, such as 2009 ISO 9004 standard, are the right way for that purpose. PMID: 25688530 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Methodology for process documentation and stabilization].
Authors: Mora JR Abstract OBJECTIVES: The methodology for process management implantation consists of four phases with their corresponding stages: The first consists of mobilizing the organization and gaining support of the executive board of the center, as well as the people that will conform the working team. The second phase, once the processes have been identified and classified, is o document and implement them with their review performed. Once the process has been implanted, with time, there is a third phase that consists of its management control that ends with the evaluation. Once the processes are evaluate...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Architecture and design of a processes map in a Urology Department].
Authors: Mora JR, Luján M Abstract Every organization with the intention to be oriented to processes management must know it is a system and what are the factors that characterize it. Health care institutions are open and mixed systems. It is in this system where the chain of value of the productive process occurs, generating a very complex integrated management system, as the productive system main recipients are people with health needs. The process management approach in clinical centers, departments and units means that, once the processes have been identified, they have to be set depending on their miss...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Definition and stabilization of processes I. Management processes and support in a Urology Department].
Authors: Pascual C, Luján M, Mora JR, Chiva V, Gamarra M Abstract The implantation of total quality management models in clinical departments can better adapt to the 2009 ISO 9004 model. An essential part of implantation of these models is the establishment of processes and their stabilization. There are four types of processes: key, management, support and operative (clinical). Management processes have four parts: process stabilization form, process procedures form, medical activities cost estimation form and, process flow chart. In this paper we will detail the creation of an essential process in a surgic...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Definition and stabilization of processes II. Clinical Processes in a Urology Department].
Authors: Pascual C, Luján M, Mora JR, Diz MR, Martín C, López MC Abstract New models in clinical management seek a clinical practice based on quality, efficacy and efficiency, avoiding variability and improvisation. In this paper we have developed one of the most frequent clinical processes in our speciality, the process based on DRG 311 or transurethral procedures without complications. Along it we will describe its components: Stabilization form, clinical trajectory, cost calculation, and finally the process flowchart. PMID: 25688534 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[High resolution for all in the clinics área of a Urology Department].
[High resolution for all in the clinics área of a Urology Department]. Arch Esp Urol. 2015 Jan-Feb;68(1):96-104 Authors: Páez A, Molina R, González N Abstract OBJECTIVES: To evaluate the performance of a one-stop clinic in terms of proportion of diagnostic-therapeutic orientation during 2013. METHODS: All patients were referred from primary care facilities in the district of Fuenlabrada, Madrid, Spain (population 221.705). Previously, referral protocols were agreed. Seven senior urologists participated. 6674 referrals (January-December 2013) were eligible. RESULTS: 4534 ref...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Adequacy of urology departments in a health care model of hospitals network].
CONCLUSIONS: Belonging to a health care model in network involves a change of attitude. It creates an organizational change, based on the processes and the results, which enables control of the management analytically, detecting the points that need to be optimized as well as those that are satisfactory. It implies developing a culture of learning and cooperation, so that the processes are fluent and have quality, to create clinical and technological projects in favor of new resource-generating research, based on the needs of the joint management of the hospitals network. The complexity of this model requires a work focuse...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Inverse innovation models in the nurse clinic of a Urology Department].
CONCLUSIONS: Implication of urological nursing staff in certain care tasks traditionally reserved to the physician is possible without increase in quality defects, obtaining an advantage in terms of economic cost and flexibility in staff organization thanks to the expansion of the competence array. PMID: 25688537 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Management of non metastatic castration resistant prostate cancer.
CONCLUSIONS: Second-line hormonal maneuvers can be an alternative in the absence of effective therapies, as long as they are well tolerated in well informed patients who refused observation or clinical trial inclusion. PMID: 25774819 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

When should we perform a bone scintigraphy in patients with new diagnosis of asymptomatic prostate cancer in order to detect bone metastasis?
Authors: Márquez-López J, Gómez-Gómez E, Anaya-Henares F, Robles-Casilda R, Requena-Tapia MJ Abstract OBJECTIVE: To define, based on PSA value, Gleason score (GS), clinical stage and age, those patients diagnosed with asymptomatic prostate cancer whose cases warrant further study of bone metastasis (BMet). METHODS: From January 2006 to May 2010, we evaluated 263 patients diagnosed with prostate cancer who were chosen for further study of bone scintigraphy following the consensus protocol accepted by the Ministry of Health of Andalusia (Integrated Andalusian Process Prostate Cancer-BP...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Quality of life after brachytherapy or robot-assisted radical prostatectomy for localized prostate cancer.
Authors: Martín-López JE, Rodríguez-López R, Romero-Tabares A, Beltran-Calvo C, Molina-López T, Baena-González V Abstract OBJECTIVES: To perform a systematic bibliographic review of the literature assessing the quality of life and complications of robotic prostatectomy (RP) versus low-dose rate brachytherapy (LDR-BT) in patients with localized prostate cancer (PCa). PubMed, EMBASE and Cochrane, Centre for Reviews and Dissemination, Emergency Care Research Institute, Web of Knowledge, Technology Evaluation Center, Clinical Evidence, Uptodate, Hayes and Drug Effectiveness Rev...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Effectiveness of low-intensity extracorporeal shock wave therapy on patients with Erectile Dysfunction (ED) who have failed to respond to PDE5i therapy. A pilot study.
The objective of this paper is to assess the effectiveness and safety of LIESWT on patients with ED who have failed to respond to PDE5i treatment. METHODS: Open label, prospective, longitudinal observational study. The study involved an uncontrolled population of 25 patients. The treatment consisted in applying 20,000 shock waves during a period of four weeks. In each session the patient received 5000 shock waves of 0.09 mJ/mm2: 1800 were applied on the penis (900 on each corpus cavernosum), and 3200 were applied on the perineum (1600 on each crus). During the active treatment and follow-up phases, all patients remaine...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Clinical and urodynamic results of alpha-blocker drug treatment in patients with lower urinary tract symptoms and benign prostatic hyperplasia.
Authors: Salinas J, Grupo URAL Abstract OBJECTIVES: To analyse the improvement in both symptoms (IPSS questionnaire) and uroflowmetry parameters (Qmax) after treatment with different alpha-blockers in patients with LUTS and BPH. The efficacy of alpha-blocker treatment on urodynamic parameters was also analysed in some patients. METHODS: An epidemiological, retrospective, multi-centre, and observational study. Twenty-five (24) Spanish healthcare centres recruited 443 patients with LUTS and BPH, and no other concurrent urological disease, they were on treatment with alpha-blockers. The study variables (demographi...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

When routine D-J implantation necessary during PNL?
Authors: Bayrak O, Seckiner I, Erturhan SM, Bulut E, Demirbag A, Erbagci A Abstract OBJECTIVE: We investigated the characteristics of patients who underwent Double-J catheter (D-J) implantation, the risk factors for prolonged urine leakage (PUL), and prediction of patients who require medical treatment. METHODS: The data of 535 adult patients who underwent PNL due to kidney stone disease between January 2005 and December 2011 in our clinic were analyzed retrospectively. Patients were divided into 2 groups: Group 1 (n=77) (14.39%) included patients with Double-J catheter due to prolonged (> 24 h) urinary leak...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Urachal adenocarcinoma of the bladder, our experience in 20 years.
CONCLUSIONS: Urachal adenocarcinomas of the bladder are rare tumors the natural history of which has not changed during the last years. Open partial cystectomy with en bloc resection of the bladder dome, urachus and the umbilicus is the standard treatment in localized stages, although minimal invasive techniques appear to have the same oncological outcomes. Pelvic lymphadenectomy is advised. Most of the patients are diagnosed at an advanced local or metastatic stage. There is a need to improve diagnostic techniques for early treatment and to find new chemotherapy protocols that can help to improve these patients' survival....
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Management of chylous fistulas, a rare complication after urologic surgery.
CONCLUSIONS: The use of octreotide appears to be an effective treatment in the management of chylous fistulae, and it is suggested by some authors as first-line treatment in the management of these, thus decreasing the complications that can appear due to chyle loss. PMID: 25774826 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

Spontaneous enterocutaneous and rectovaginal fistula: potential complications during therapy with anti-angiogenic drugs in renal cancer.
We present two cases of enterovaginal and enterocutaneous fistulae associated to treatment with pazopanib, which is an angiogenesis inhibitor for the treatment of metastatic renal cancer. The times from drug administration and the first appearance of a fistula were 6 and 16 months, respectively. None of the cases had a history of surgery or radiotherapy in the area where the complication was observed. Enterovaginal and enterocutaneous fistula represent less than 1% of all published complications caused by the use of antiangiogenic drugs. However, they must be taken into account as the reported mortality rate is close to 30...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[What has changed in the epidemiology and screening of prostate cancer?].
CONCLUSIONS; Systematic screening, despite inconsistencies in some studies, seems to improve prostate cancer specific mortality. The introduction of new biomarkers, imaging techniques such as mpMRI as well as less aggressive therapeutic alternatives, probably open windows to the future for a better diagnosis and treatment of the disease. PMID: 25948794 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Current role of protatic specific antigen (PSA) and its by-products in the diagnosis of prostate cancer].
Authors: Placer J, Planas J, Celma A, Morote J Abstract Incorporation of prostatic specific antigen (PSA) to clinical practice was a revolution in the diagnosis and modified the epidemiology of prostate cancer (PCa). Although it lacks of many characteristics of an ideal tumor marker, it is the marker most used for diagnosis and follow up of any kind of cancer. It represents the best clinical tool we have available today for screening and staging of PCa. On the contrary, its greatest limitation is the lack of tumor specificity. The use of PSA by-products and molecular isoforms tries to solve, at least partially, its...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Non- PSA serum markers for the diagnosis of PCa].
Authors: Mengual L, Musquera M, Ciudin A, Ribal MJ Abstract Prostate cancer (PCa) is the most common male malignancy in our population. Over the past two decades, the prostate specific antigen (PSA) has been widely used for screening, diagnosis and monitoring of prostate cancer. Routine use of PSA has been continuing subject to controversy due to its limited specificity, which is derived from the fact that serum PSA levels are produced in a variety of non-neoplastic conditions. The shortcomings in sensitivity and specificity of PSA have promoted the search for new biomarkers to improve diagnostic performance. The u...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Update on the diagnosis of PCa in urine. The current role of urine markers].
Authors: Fernandez-Serra A, Casanova-Salas I, Rubio L, Calatrava A, García-Flores M, García-Casado Z, López-Guerrero JA, Rubio-Briones J Abstract Prostate cancer (PCa) is still a main health issue, in fact it is responsible for 10% of cancer deaths across Europe. The morphology of the prostate gland makes urine an ideal sample, non invasive, for determination both diagnostic and prognostic biomarkers. We use urinary PCA3 levels to indicate a prostate biopsy, and it is the only urinary biomarkers in PCa with FDA approval for clinical use. Many other biomarkers based on the expression of specific...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Role of tissue markers on diagnosis, prognosis and monitoring of prostate cancer].
CONCLUSIONS: Since prostate cancer is a heterogeneous disease, having a defined set of markers for early diagnosis, prognosis and follow-up, is clinically relevant. Some of these new markers can now be used to complement the conventional histopathologic diagnosis, as well as, to help already established parameters assessing prognosis. PMID: 25948798 [PubMed - in process] (Source: Archivos Espanoles de Urologia)
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Usefulness of clinical nomograms and predictive models for pca. Predictive clinical factors of tumor agressiveness].
Authors: Borque Á, Esteban LM, Sanz G, Rubio-Briones J, Gil Sanz MJ Abstract In this narrative review we present the natural evolution of predictive models to their presentation in the nomogram format. We show their clinical usefulness and the objective parameters that contribute to their clinical use: calibration, discrimination, decision curves and probability density functions. We continue detailing the various existing predictive models/nomograms in relation to prostate cancer aggressiveness before and after biopsy, before and after primary treatment, recurrence and castration resistance. Finally we incl...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research

[Conventional transrectal ultrasound guided biopsy. Current role, indications, techniques and limitations].
CONCLUSIONS: Ultrasound guided prostatic biopsy is the main diagnostic method for prostate cancer yet. The information it gives is greatly relevant for staging, prognostic evaluation and therapeutic decision-making. Nevertheless, its limitations are evident: low sensitivity, overdiagnosis, complicacions, patient's distress, etc. There are two lines of development to improve its efficiency. The one aiming to reduce the number of biopsies and cores by selectively targeting the findings of the MRI and the one that continues systematizing schemes with increasing number of cores to achieve the optimal sampling. Technical advanc...
Source: Archivos Espanoles de Urologia - December 21, 2015 Category: Urology & Nephrology Tags: Arch Esp Urol Source Type: research