Nasal Rim Sign: A clinical manifestation of dermatomyositis
(Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - March 5, 2024 Category: Rheumatology Authors: Sweta Subhadarshani,
Madeline Hunt,
Kerith Spicknall Tags: Clinical Image Source Type: research
Quantitative whole-body muscle MRI in idiopathic inflammatory myopathies including polymyositis with mitochondrial pathology: indications for a disease spectrum
AbstractObjectiveInflammatory myopathies (IIM) include dermatomyositis (DM), sporadic inclusion body myositis (sIBM), immune-mediated necrotizing myopathy (IMNM), and overlap myositis (OLM)/antisynthetase syndrome (ASyS). There is also a rare variant termed polymyositis with mitochondrial pathology (PM-Mito), which is considered a sIBM precursor. There is no information regarding muscle MRI for this rare entity. The aim of this study was to compare MRI findings in IIM, including PM-Mito.MethodsThis retrospective analysis included 41 patients (7 PM-Mito, 11 sIBM, 11 PM/ASyS/OLM, 12 IMNM) and 20 healthy controls. Pattern of ...
Source: Journal of Neurology - March 5, 2024 Category: Neurology Source Type: research
Performance of the 2017 EULAR/ACR Classification Criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups: a scoping review
Clin Exp Rheumatol. 2024 Feb 28. doi: 10.55563/clinexprheumatol/vuc5py. Online ahead of print.ABSTRACTThe 2017 EULAR/ACR classification criteria for adult/juvenile idiopathic inflammatory myopathies (IIM) were established using a data-driven approach by an international group of myositis experts to allow classification of IIM and its major subtypes. Since their publication, the performance of the criteria has been tested in multiple cohorts worldwide and significant limitations have been identified. Moreover, the understanding and classification of IIM have evolved since 2017. This scoping review was undertaken as part of ...
Source: Clinical and Experimental Rheumatology - March 4, 2024 Category: Rheumatology Authors: Didem Saygin Stefanie Glaubitz Rachel Zeng Matteo Bottai Marianne de Visser Mazen M Dimachkie David Fiorentino Ingrid Gerhardson Masataka Kuwana Frederick W Miller Merrilee Needham Lisa G Rider Yasser Salem Silke Schl üter Samuel K Shinjo Guochun Wang Vi Source Type: research
Anti-synthetase syndrome is associated with a higher risk of hospitalization among patients with idiopathic inflammatory myopathy and COVID-19
ConclusionASyS and family oxygen supplement were first identified as risk factors for COVID-19-related hospitalization in patients with IIMs. JAKi pre-exposure might protect IIM patients against severe COVID-19 complications. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - March 4, 2024 Category: Allergy & Immunology Source Type: research
Spontaneous regression of acute fibrinous organizing pneumonia induced by COVID-19 vaccination: A case report
Respir Investig. 2024 Feb 28;62(3):356-359. doi: 10.1016/j.resinv.2024.01.014. Online ahead of print.ABSTRACTA 42-year-old woman visited our hospital with complaints of fever, muscle pain, and dyspnea one week after receiving the coronavirus disease 2019 (COVID-19) vaccine. Chest high-resolution computed tomography showed a patchy consolidation and ground-glass attenuation in the both lungs, consistent with acute interstitial pneumonia. Transbronchial lung cryobiopsy revealed organizing pneumonia with marked intra-alveolar fibrin, and pathologically diagnosed as acute fibrinous organizing pneumonia (AFOP). Other causative ...
Source: Pain Physician - February 29, 2024 Category: Anesthesiology Authors: Sanshiro Haga Ryota Otoshi Akimasa Sekine Taichi Kaneko Chieri Yamada Tomohisa Baba Shigeru Komatsu Tomoe Sawazumi Tamiko Takemura Takashi Ogura Source Type: research
Spontaneous regression of acute fibrinous organizing pneumonia induced by COVID-19 vaccination: A case report
Respir Investig. 2024 Feb 28;62(3):356-359. doi: 10.1016/j.resinv.2024.01.014. Online ahead of print.ABSTRACTA 42-year-old woman visited our hospital with complaints of fever, muscle pain, and dyspnea one week after receiving the coronavirus disease 2019 (COVID-19) vaccine. Chest high-resolution computed tomography showed a patchy consolidation and ground-glass attenuation in the both lungs, consistent with acute interstitial pneumonia. Transbronchial lung cryobiopsy revealed organizing pneumonia with marked intra-alveolar fibrin, and pathologically diagnosed as acute fibrinous organizing pneumonia (AFOP). Other causative ...
Source: Pain Physician - February 29, 2024 Category: Anesthesiology Authors: Sanshiro Haga Ryota Otoshi Akimasa Sekine Taichi Kaneko Chieri Yamada Tomohisa Baba Shigeru Komatsu Tomoe Sawazumi Tamiko Takemura Takashi Ogura Source Type: research
Myofascial edema of gastrocnemius: A prominent MRI characteristic in dermatomyositis patients with anti-transcriptional intermediate factor 1- γ antibody
CONCLUSIONS: Myofascial edema of gastrocnemius was a prominent characteristic of anti-TIF1-γ-positive DM. Early detection of muscle edema, as well as CK levels, may be helpful for monitoring disease activity.PMID:38385674 | PMC:PMC10883095 | DOI:10.1111/cns.14647 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - February 22, 2024 Category: Neuroscience Authors: Chao Zhen Bing Zhao Jingzhen He Li Wei Chuanzhu Yan Tingjun Dai Ying Hou Source Type: research
Myofascial edema of gastrocnemius: A prominent MRI characteristic in dermatomyositis patients with anti-transcriptional intermediate factor 1- γ antibody
CONCLUSIONS: Myofascial edema of gastrocnemius was a prominent characteristic of anti-TIF1-γ-positive DM. Early detection of muscle edema, as well as CK levels, may be helpful for monitoring disease activity.PMID:38385674 | PMC:PMC10883095 | DOI:10.1111/cns.14647 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - February 22, 2024 Category: Neuroscience Authors: Chao Zhen Bing Zhao Jingzhen He Li Wei Chuanzhu Yan Tingjun Dai Ying Hou Source Type: research
Myofascial edema of gastrocnemius: A prominent MRI characteristic in dermatomyositis patients with anti-transcriptional intermediate factor 1- γ antibody
CONCLUSIONS: Myofascial edema of gastrocnemius was a prominent characteristic of anti-TIF1-γ-positive DM. Early detection of muscle edema, as well as CK levels, may be helpful for monitoring disease activity.PMID:38385674 | PMC:PMC10883095 | DOI:10.1111/cns.14647 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - February 22, 2024 Category: Neuroscience Authors: Chao Zhen Bing Zhao Jingzhen He Li Wei Chuanzhu Yan Tingjun Dai Ying Hou Source Type: research
A bibliometric analysis of the research status and trends in studies on polymyositis and dermatomyositis with interstitial lung disease from 2000 to 2022 using Web of Science
ConclusionThis study found that research on PM/DM with ILD has increased over time, and scholars are paying more attention to this field. The development of new drugs for the management, treatment, and prevention of PM/DM with ILD is the primary task of researchers and a direction for future research in this field. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - February 20, 2024 Category: Allergy & Immunology Authors: Xiao ‐Na Ma,
Wei Feng,
Shu‐Lin Chen,
Xiao‐Qin Zhong,
Xue‐Xia Zheng,
Chang‐Song Lin,
Qiang Xu Tags: REVIEW ARTICLE Source Type: research
Treatment strategies in MDA5-positive clinically amyopathic dermatomyositis: a single-center retrospective analysis
AbstractMelanoma differentiation-associated protein 5 (MDA5) antibody positive amyopathic dermatomyositis (DM) is a rare inflammatory disease. So far, there is no official treatment guideline in MDA5 amyopathic dermatomyositis, but early and aggressive immunosuppressive combination treatment can induce a stable remission. We retrospectively analyzed a cohort of eight patients (malen = 5) that were diagnosed with MDA5-positive amyopathic DM. Patient data comprised demographics, CT-guided diagnosis of pulmonary involvement, pulmonary function testing including forced vital capacity (FVC) and diffusing capacity for carbon...
Source: Clinical and Experimental Medicine - February 17, 2024 Category: Research Source Type: research
