Nintedanib could potentially lead to improvements in anti-melanoma differentiation-associated 5 dermatomyositis-associated interstitial lung disease
CONCLUSIONS: Nintedanib may be effective for improving clinical symptoms, laboratory parameters, lung lesions, and survival in anti-MDA5+ DM. Diarrhoea was the most common adverse event associated with nintedanib, although the drug was well tolerated by most patients.PMID:38153137 | DOI:10.55563/clinexprheumatol/c0i032 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Xixia Chen Wei Jiang Qiwen Jin Sang Lin Lu Zhang Qinglin Peng Hongliang Sun Yuli Wang Xin Lu Aiping Song Guochun Wang Yongpeng Ge Source Type: research
Treatment of refractory psoriasis with dermatomyositis using upadacitinib
Clin Exp Rheumatol. 2023 Dec 27. doi: 10.55563/clinexprheumatol/ki4jbt. Online ahead of print.NO ABSTRACTPMID:38153132 | DOI:10.55563/clinexprheumatol/ki4jbt (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Zining Xu Bingyang Xu Bin Zhao Hailong Gao Shuhong Ye Jiawen Wu Source Type: research
Expansion of exhausted CD8+ T cells associates with increased pulmonary fungal infection risk in anti-melanoma differentiation associated gene 5 dermatomyositis
CONCLUSIONS: CD8 T cells from patients with anti-MDA5+ DM show significant exhausted phenotype, and increased exhausted CD8 T cells were associated with high risk of pulmonary fungal infection.PMID:38153165 | DOI:10.55563/clinexprheumatol/e51d3m (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Yue-Tong Xu Zheng-Yi Cao Sang Lin Xiao-Ming Shu Xin Lu Guo-Chun Wang Qing-Lin Peng Source Type: research
Nintedanib could potentially lead to improvements in anti-melanoma differentiation-associated 5 dermatomyositis-associated interstitial lung disease
CONCLUSIONS: Nintedanib may be effective for improving clinical symptoms, laboratory parameters, lung lesions, and survival in anti-MDA5+ DM. Diarrhoea was the most common adverse event associated with nintedanib, although the drug was well tolerated by most patients.PMID:38153137 | DOI:10.55563/clinexprheumatol/c0i032 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Xixia Chen Wei Jiang Qiwen Jin Sang Lin Lu Zhang Qinglin Peng Hongliang Sun Yuli Wang Xin Lu Aiping Song Guochun Wang Yongpeng Ge Source Type: research
Treatment of refractory psoriasis with dermatomyositis using upadacitinib
Clin Exp Rheumatol. 2023 Dec 27. doi: 10.55563/clinexprheumatol/ki4jbt. Online ahead of print.NO ABSTRACTPMID:38153132 | DOI:10.55563/clinexprheumatol/ki4jbt (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Zining Xu Bingyang Xu Bin Zhao Hailong Gao Shuhong Ye Jiawen Wu Source Type: research
Nintedanib could potentially lead to improvements in anti-melanoma differentiation-associated 5 dermatomyositis-associated interstitial lung disease
CONCLUSIONS: Nintedanib may be effective for improving clinical symptoms, laboratory parameters, lung lesions, and survival in anti-MDA5+ DM. Diarrhoea was the most common adverse event associated with nintedanib, although the drug was well tolerated by most patients.PMID:38153137 | DOI:10.55563/clinexprheumatol/c0i032 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Xixia Chen Wei Jiang Qiwen Jin Sang Lin Lu Zhang Qinglin Peng Hongliang Sun Yuli Wang Xin Lu Aiping Song Guochun Wang Yongpeng Ge Source Type: research
Expansion of exhausted CD8+ T cells associates with increased pulmonary fungal infection risk in anti-melanoma differentiation associated gene 5 dermatomyositis
CONCLUSIONS: CD8 T cells from patients with anti-MDA5+ DM show significant exhausted phenotype, and increased exhausted CD8 T cells were associated with high risk of pulmonary fungal infection.PMID:38153165 | DOI:10.55563/clinexprheumatol/e51d3m (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Yue-Tong Xu Zheng-Yi Cao Sang Lin Xiao-Ming Shu Xin Lu Guo-Chun Wang Qing-Lin Peng Source Type: research
Treatment of refractory psoriasis with dermatomyositis using upadacitinib
Clin Exp Rheumatol. 2023 Dec 27. doi: 10.55563/clinexprheumatol/ki4jbt. Online ahead of print.NO ABSTRACTPMID:38153132 | DOI:10.55563/clinexprheumatol/ki4jbt (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Zining Xu Bingyang Xu Bin Zhao Hailong Gao Shuhong Ye Jiawen Wu Source Type: research
Expansion of exhausted CD8+ T cells associates with increased pulmonary fungal infection risk in anti-melanoma differentiation associated gene 5 dermatomyositis
CONCLUSIONS: CD8 T cells from patients with anti-MDA5+ DM show significant exhausted phenotype, and increased exhausted CD8 T cells were associated with high risk of pulmonary fungal infection.PMID:38153165 | DOI:10.55563/clinexprheumatol/e51d3m (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Yue-Tong Xu Zheng-Yi Cao Sang Lin Xiao-Ming Shu Xin Lu Guo-Chun Wang Qing-Lin Peng Source Type: research
Nintedanib could potentially lead to improvements in anti-melanoma differentiation-associated 5 dermatomyositis-associated interstitial lung disease
CONCLUSIONS: Nintedanib may be effective for improving clinical symptoms, laboratory parameters, lung lesions, and survival in anti-MDA5+ DM. Diarrhoea was the most common adverse event associated with nintedanib, although the drug was well tolerated by most patients.PMID:38153137 | DOI:10.55563/clinexprheumatol/c0i032 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 28, 2023 Category: Rheumatology Authors: Xixia Chen Wei Jiang Qiwen Jin Sang Lin Lu Zhang Qinglin Peng Hongliang Sun Yuli Wang Xin Lu Aiping Song Guochun Wang Yongpeng Ge Source Type: research
Clinical features of anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis with macrophage activation syndrome
CONCLUSIONS: Among anti-MDA5-positive DM, Infection, DM typical rashes, and higher serum levels of ferritin, AST, LDH, and CK were more common in patients complicated with MAS. The mortality of patients with MAS was high, particularly among patients who were older, given more combination therapy with TOF, and had RP-ILD, infection, heart failure and renal impairment.PMID:38147318 | DOI:10.55563/clinexprheumatol/2537nv (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 26, 2023 Category: Rheumatology Authors: Lu Yang Panpan Zhang Qihua Yang Chunyi Zhang Wenjuan Guan Shengyun Liu Source Type: research
The clinical characteristics of subcutaneous and mediastinal emphysema in anti-melanoma differentiation-associated 5 positive dermatomyositis associated with interstitial lung disease
CONCLUSIONS: 1. SE/ME is not uncommon in anti-MDA5-positive DM-ILD and is an important factor associated with poor patient prognosis. 2. The occurrence of SE/ME is correlated with high levels of serum ferritin and is not related to anti-Ro-52 antibodies. 3. Rheumatologists should pay close attention to SE/ME caused by positive pressure ventilation in anti-MDA5-positive DM-ILD patients.PMID:38147317 | DOI:10.55563/clinexprheumatol/84kd56 (Source: Clinical and Experimental Rheumatology)
Source: Clinical and Experimental Rheumatology - December 26, 2023 Category: Rheumatology Authors: Wenhan Huang Dandan Chen Feifeng Ren Lei Luo Jun Zhou Dongmei Huang Mengxue Tian Kechen Qian Yanqiu Jiang Lin Tang Source Type: research
A rare case of cutaneous lupus erythematosus presenting with periorbital erythema and edema
In conclusion, it should be kept in mind that periorbital erythema can develop as a rare variant of CLE and can be misdiagnosed as contact dermatitis, dermatomyositis, sarcoidosis, or cutaneous lymphoma. Additionally, the ANA and anti-dsDNA antibodies are often found to be negative in these cases. In establishing the diagnosis, firstly considering the disease, followed by histopathological examinations and laboratory tests, is crucial.PMID:38148123 | DOI:10.1177/09612033231224767 (Source: Lupus)
Source: Lupus - December 26, 2023 Category: Rheumatology Authors: Fatmanur Hac ınecipoğlu Beng ü Çevirgen Cemil Selda Pelin Kartal Sehbal Arslankoz Source Type: research
