Clinical features of anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis with macrophage activation syndrome

CONCLUSIONS: Among anti-MDA5-positive DM, Infection, DM typical rashes, and higher serum levels of ferritin, AST, LDH, and CK were more common in patients complicated with MAS. The mortality of patients with MAS was high, particularly among patients who were older, given more combination therapy with TOF, and had RP-ILD, infection, heart failure and renal impairment.PMID:38147318 | DOI:10.55563/clinexprheumatol/2537nv

Source: Clinical and Experimental Rheumatology - December 26, 2023 Category: Rheumatology Authors: Lu Yang Panpan Zhang Qihua Yang Chunyi Zhang Wenjuan Guan Shengyun Liu Source Type: research